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Results: 135
Fossils reveal the complex evolutionary history of the mammalian regionalized spine.
KE Jones, KD Angielczyk, PD Polly, JJ Head, V Fernandez, JK Lungmus, S Tulga, SE Pierce
Jan 10, 2019
A unique characteristic of mammals is a vertebral column with anatomically distinct regions, but when and how this trait evolved remains unknown. We reconstructed vertebral regions and their morphological disparity in the...
Human cytomegalovirus-specific cytotoxic T cells. Relative frequency of stage-specific CTL recognizing the 72-kD immediate early protein and glycoprotein B expressed by recombinant vaccinia viruses.
CTL are held to be an important host defense mechanism in persistent herpes-virus infections. We have therefore studied the nature and specificity of human cytomegalovirus (HCMV)-specific CTL in normal persistently infected...
Identification of Sex and Aging Differences in C57BL/6-NClr Mice on the Ketogenic Diet
Ken Sprankle
Jan 01, 0001
The ketogenic diet (KD) is a high-fat, low-carbohydrate diet that results in the elevation of serum ketone bodies, known as ketosis. This metabolic consequence has been suggested as a method for treating neurological conditions...
ketogenic diet Mice adipose Motor Cognition Exercise Biology Life Sciences Medicine and Health Sciences Public Health
Published by: Ursinus College
Sex- and Age-Specific Differences in Mice Fed a Ketogenic Diet
Kenyon W. Sprankle, Mya Knappenberger, Erica J. Locke, Jack Thompson, Madison Vinovrski, Kaylin Knapsack, Stephen C. Kolwicz, Jr.
Jan 01, 0001
The ketogenic diet (KD) is a high-fat, low-carbohydrate diet that results in the elevation of serum ketone bodies, known as ketosis. This metabolic consequence has been suggested as a method for treating neurological conditions...
Published by: Ursinus College
King-Devick concussion test performs poorly as a screening tool in elite rugby union players
BACKGROUND: The King-Devick (KD) test is an objective clinical test of eye movements that has been used to screen for concussion. We characterised the accuracy of the KD test and the World Rugby Head Injury Assessment (HIA-1)...
The evolution of the tetrapod humerus
The present study explores the macroevolutionary dynamics of shape changes in the humeri of all major grades and clades of early tetrapods and their fish-like forerunners. Coordinate point eigenshape analysis applied to...
Insights into the Substrate Specificity of Archaeal Entner-Doudoroff Aldolases
Viatcheslav Zaitsev, Ulrike Johnsen, Matthias Reher, Marius Ortjohann, Garry Taylor, Michael Danson, Peter Schönheit, Susan Crennell
Jul 03, 2018
The thermoacidophilic archaea Picrophilus torridus and Sulfolobus solfataricus catabolize glucose via a nonphosphorylative Entner-Doudoroff pathway and a branched Entner-Doudoroff pathway, respectively. Key enzymes for these...
Insights into the Substrate Specificity of Archaeal Entner-Doudoroff Aldolases
Viatcheslav Zaitsev, Ulrike Johnsen, Matthias Reher, Marius Ortjohann, Garry Taylor, Michael Danson, Peter Schönheit, Susan Crennell
Jul 03, 2018
The thermoacidophilic archaea Picrophilus torridus and Sulfolobus solfataricus catabolize glucose via a nonphosphorylative Entner-Doudoroff pathway and a branched Entner-Doudoroff pathway, respectively. Key enzymes for these...
The evolution of the tetrapod humerus
The present study explores the macroevolutionary dynamics of shape changes in the humeri of all major grades and clades of early tetrapods and their fish-like forerunners. Coordinate point eigenshape analysis applied to...
King-Devick concussion test performs poorly as a screening tool in elite rugby union players
BACKGROUND: The King-Devick (KD) test is an objective clinical test of eye movements that has been used to screen for concussion. We characterised the accuracy of the KD test and the World Rugby Head Injury Assessment (HIA-1)...
Diffusion and sorption of trace organic micropollutants in biofilm with varying thickness
Elena Torresi, Fabio Polesel, Kai Bester, Magnus Christensson, Barth F. Smets, Stefan Trapp, Henrik R. Andersen, Benedek Gy. Plosz
Oct 15, 2017
Solid-liquid partitioning is one of the main fate processes determining the removal of micropollutants in wastewater. Little is known on the sorption of micropollutants in biofilms, where molecular diffusion may significantly...
Ketogenic Diets and Exercise Performance
The ketogenic diet (KD) has gained a resurgence in popularity due to its purported reputation for fighting obesity. The KD has also acquired attention as an alternative and/or supplemental method for producing energy in the form...
Ketosis endurance exercise ketone supplements obesity ketone bodies metabolism Dietetics and Clinical Nutrition Exercise Science Medicine and Health Sciences
Published by: Ursinus College
The Effects of Fasting or Ketogenic Diet on Endurance Exercise Performance and Metabolism in Female Mice
The promotion of ketone body (KB) metabolism via ketosis has been suggested as a strategy to increase exercise performance. However, studies in humans and animals have yielded inconsistent results. The purpose of the current...
nutritional ketosis Lipid Metabolism ketone body metabolism Glycogen Triglycerides Exercise Physiology
Published by: Ursinus College
The Contributions of Ketogenic Diet to Behavioral Alterations and Brain Development in C57BL/6-NClr Mice
Mya Knappenberger
Jan 01, 0001
The prevalence of obesity and hyperactivity in children have increased over the last several years. However, research has yet to establish a known association between the development of obesity and behavioral disorders. The...
Published by: Ursinus College
Spastin couples microtubule severing to membrane traffic in completion of cytokinesis and secretion.
Mutations in the gene encoding the microtubule (MT)-severing protein spastin are the most common cause of hereditary spastic paraplegia, a genetic condition in which axons of the corticospinal tracts degenerate. We show that not...
Prioritised challenges in the management of acute knee dislocations are stiffness, obesity, treatment delays and associated limb-threatening injuries
Michael Held, Robert C Schenck, Vikas Khanduja, Túlio Vinícius de Oliveira Campos, Sachin Tapasvi, Andy Williams, Wai Pan Yau, Christopher Harner, Authorship group ‘Knee surgery in LRS’
Mar 09, 2021
OBJECTIVES: Heterogeneous patient factors and injury mechanisms result in a great variety of injury patterns encountered in knee dislocations (KD). Attempts to improve outcome can focus on a wide range of challenges. The aim of...
Diffusion and sorption of trace organic micropollutants in biofilm with varying thickness
Elena Torresi, Fabio Polesel, Kai Bester, Magnus Christensson, Barth F. Smets, Stefan Trapp, Henrik R. Andersen, Benedek Gy. Plosz
Oct 15, 2017
Solid-liquid partitioning is one of the main fate processes determining the removal of micropollutants in wastewater. Little is known on the sorption of micropollutants in biofilms, where molecular diffusion may significantly...
Effect of the early-life nutritional environment on fecundity and fertility of mammals.
The early-life developmental environment is instrumental in shaping our overall adult health and well-being. Early-life diet and endocrine exposure may independently, or in concert with our genetic constitution, induce a...
π-Clamp-Mediated Homo- and Heterodimerization of Single-Domain Antibodies via Site-Specific Homobifunctional Conjugation.
Ross J Taylor, Mauricio Aguilar Rangel, Michael B Geeson, Pietro Sormanni, Michele Vendruscolo, Gonçalo JL Bernardes
Aug 14, 2022
Post-translational protein-protein conjugation produces bioconjugates that are unavailable via genetic fusion approaches. A method for preparing protein-protein conjugates using π-clamp-mediated cysteine arylation with...
Creature of Habit
Our daily lives involve high levels of repetition of activities within similar contexts. We buy the same foods from the same grocery store, cook with the same spices, and typically sit at the same place at the dinner table....
Interventions to increase physical activity in children 0-5 years old
OBJECTIVE: The objective of the study is to evaluate the effectiveness of interventions to increase physical activity (PA) in 0-5 year olds and to determine what works, for whom, in what circumstances. DESIGN: Systematic review...
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