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Multi-Solitons, Multi-Breathers and Multi-Rational Solutions of Integrable Extensions of the Kadomtsev–Petviashvili Equation in Three Dimensions
The celebrated Korteweg–de Vries and Kadomtsev–Petviashvili (KP) equations are prototypical examples of integrable evolution equations in one and two spatial dimensions, respectively. The question of constructing...
p140Cap Controls Female Fertility in Mice Acting via Glutamatergic Afference on Hypothalamic Gonadotropin-Releasing Hormone Neurons.
Mattia Camera, Isabella Russo, Valentina Zamboni, Alessandra Ammoni, Simona Rando, Alessandro Morellato, Irene Cimino, Costanza Angelini, Paolo Giacobini, Roberto Oleari, Federica Amoruso, Anna Cariboni, Isabelle Franceschini, Emilia Turco, Paola Defilippi, Giorgio R Merlo
Feb 28, 2022
p140Cap, encoded by the gene SRCIN1 (SRC kinase signaling inhibitor 1), is an adaptor/scaffold protein highly expressed in the mouse brain, participating in several pre- and post-synaptic mechanisms. p140Cap knock-out (KO)...
A Comparative Analysis of Deep Learning Approaches for Network Intrusion Detection Systems (N-IDSs)
Recently, due to the advance and impressive results of deep learning techniques in the fields of image recognition, natural language processing and speech recognition for various long-standing artificial intelligence (AI) tasks...
Published by: IGI Global Scientific Publishing
Dysregulation at multiple points of the kynurenine pathway is a ubiquitous feature of renal cancer
Nick Hornigold, Karen R Dunn, Rachel A Craven, Alexandre Zougman, Sebastian Trainor, Rebecca Shreeve, Joanne Brown, Helen Sewell, Michael Shires, Margaret Knowles, Tsutomu Fukuwatari, Eamonn R Maher, Julie Burns, Selina Bhattarai, Mini Menon, Alvis Brazma, Ghislaine Scelo, Lara Feulner, Yasser Riazalhosseini, Mark Lathrop, Adrian Harris, Peter J Selby, Rosamonde E Banks, Naveen S Vasudev
May 22, 2020
BACKGROUND: Indoleamine 2,3-dioxygenase (IDO), the first step in the kynurenine pathway (KP), is upregulated in some cancers and represents an attractive therapeutic target given its role in tumour immune evasion. However, the...
Integrable nonlinear evolution equations in three spatial dimensions.
AS Fokas
Jul 27, 2022
There are integrable nonlinear evolution equations in two spatial variables. The solution of the initial value problem of these equations necessitated the introduction of novel mathematical formalisms. Indeed, the classical...
Possible Consequences of Climate Change on Survival, Productivity and Reproductive Performance, and Welfare of Himalayan Yak (Bos grunniens).
Yak are adapted to the extreme cold, low oxygen, and high solar radiation of the Himalaya. Traditionally, they are kept at high altitude pastures during summer, moving lower in the winter. This system is highly susceptible to...
An Ising machine based on networks of subharmonic electrical resonators
Abstract Combinatorial optimization problems are difficult to solve with conventional algorithms. Here we explore networks of nonlinear electronic oscillators evolving dynamically towards the...
Clifford lattices and a conformal generalization of Desargues' theorem
Lattices composed of Clifford point–circle configurations provide a geometric representation of the discrete Schwarzian KP (dSKP) equation. Based on an An perspective on such lattices, it is shown that their integrability, and...
Integrable nonlinear evolution equations in three spatial dimensions.
AS Fokas
Sep 02, 2022
There are integrable nonlinear evolution equations in two spatial variables. The solution of the initial value problem of these equations necessitated the introduction of novel mathematical formalisms. Indeed, the classical...
Mechanistic insights into the more potent effect of KP-54 compared to KP-10 in vivo
Possible Consequences of Climate Change on Survival, Productivity and Reproductive Performance, and Welfare of Himalayan Yak (Bos grunniens).
Yak are adapted to the extreme cold, low oxygen, and high solar radiation of the Himalaya. Traditionally, they are kept at high altitude pastures during summer, moving lower in the winter. This system is highly susceptible to...
SIRS Triggered by Acute Right Ventricular Function, Mimicked Septic Shock.
BACKGROUND: The systemic inflammatory response syndrome (SIRS) is a complex immune response which can be precipitated by non-infectious aetiologies such as trauma, burns or pancreatitis. Addressing the underlying cause is...
Amyloid-Like Aggregation in Native Protein and its Suppression in the Bio-Conjugated Counterpart
Prevention of protein aggregation and thus stabilization of proteins has large biological and biotechnological implications. Here we introduce Dynamic Light Scattering (DLS) and DLS-based microrheology to show how native...
Clifford lattices and a conformal generalization of Desargues' theorem
Lattices composed of Clifford point–circle configurations provide a geometric representation of the discrete Schwarzian KP (dSKP) equation. Based on an An perspective on such lattices, it is shown that their integrability, and...
Efficient Triplet Exciton Fusion in Molecularly Doped Polymer Light-Emitting Diodes.
D Di, L Yang, JM Richter, L Meraldi, RM Altamimi, AY Alyamani, D Credgington, KP Musselman, JL MacManus-Driscoll, RH Friend
Mar 08, 2017
A novel method for quantification of gemcitabine and its metabolites 2',2'-difluorodeoxyuridine and gemcitabine triphosphate in tumour tissue by LC-MS/MS
Tashinga E Bapiro, Frances M Richards, Mae A Goldgraben, Kenneth P Olive, Basetti Madhu, Kristopher K Frese, Natalie Cook, Michael A Jacobetz, Donna-Michelle Smith, David A Tuveson, John R Griffiths, Duncan I Jodrell
Nov 30, 2017
PURPOSE: To develop a sensitive analytical method to quantify gemcitabine (2',2'-difluorodeoxycytidine, dFdC) and its metabolites 2',2'-difluorodeoxyuridine (dFdU) and 2',2'-difluorodeoxycytidine-5'-triphosphate (dFdCTP)...
Perspective
RLZ Hoye, RE Brandt, Y Ievskaya, S Heffernan, KP Musselman, T Buonassisi, JL MacManus-Driscoll
May 06, 2015
Colonisation with ESBL-producing and carbapenemase-producing Enterobacteriaceae, vancomycin-resistant enterococci, and meticillin-resistant Staphylococcus aureus in a long-term care facility over one year.
Catherine Ludden, Martin Cormican, Akke Vellinga, James R Johnson, Bernie Austin, Dearbháile Morris
Sep 29, 2016
BACKGROUND: This study examined colonisation with and characteristics of antimicrobial-resistant organisms among residents of a long-term care facility (LTCF) over one year, including strain persistence and molecular diversity...
Aged Aged 80 and over Bacterial Proteins Carrier State Electrophoresis Gel Pulsed-Field Enterobacteriaceae Enterobacteriaceae Infections Escherichia coli Escherichia coli Infections Female Gram-Negative Bacterial Infections Gram-Positive Bacterial Infections Humans Klebsiella Infections Klebsiella pneumoniae Long-Term Care Male Methicillin Methicillin-Resistant Staphylococcus aureus molecular epidemiology Nursing Homes Polymerase Chain Reaction Staphylococcal Infections Vancomycin-Resistant Enterococci beta-Lactamases
Glucagon-Like Peptide-1 and its Analogues Act in the Dorsal Raphe and Modulate Central Serotonin to Reduce Appetite and Body Weight.
RH Anderberg, JE Richard, K Eerola, LL Ferreras, EB Nordbeck, C Hansson, H Nissbrandt, F Berqquist, FM Gribble, F Reimann, I Wernstedt-Asterholm, C Lamy, KP Skibicka
Mar 22, 2017
Single-nucleus RNA-seq2 reveals functional crosstalk between liver zonation and ploidy.
ML Richter, IK Deligiannis, K Yin, A Danese, E Lleshi, P Coupland, CA Vallejos, KP Matchett, NC Henderson, M Colome-Tatche, CP Martinez-Jimenez
Aug 13, 2021
Animals Biomarkers Cell Nucleus Chronic Disease frozen sections Gene Expression Profiling Gene Expression Regulation Gene Ontology Hepatocytes Liver Liver Diseases Mice Inbred C57BL Ploidies Regeneration Sequence Analysis RNA Single-Cell Analysis Stem Cells Transcription Factors Transcription Genetic
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