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Results: 43
Laboratory-Assessed Markers of Cardiometabolic Health and Associations with GIS-Based Measures of Active-Living Environments.
Active-living-friendly environments have been linked to physical activity, but their relationships with specific markers of cardiometabolic health remain unclear. We estimated the associations between active-living environments...
blood pressure body-mass index cardiometabolic health neighborhood physical-activity environments physical activity Biomarkers Canada Cardiovascular Diseases Cross-Sectional Studies Exercise Female Geographic Information Systems Health Surveys Humans Male Metabolic Diseases Middle Aged Protective factors Residence Characteristics Risk Factors
Lexical neutrality in environmental health research
Neighbourhood environments have important implications for human health. In this piece, we reflect on the environments and health literature and argue that precise use of language is critical for acknowledging the complex and...
Steps, moderate-to-vigorous physical activity, and cardiometabolic profiles.
The relative benefits of meeting the current moderate-to-vigorous intensity physical activity (MVPA) and active step count recommendations are unknown. Using robust linear regressions, we compared cardiometabolic marker...
The Economics of Biodiversity
Abstract This Afterword to The Economics of Biodiversity: The Dasgupta Review discusses (i) the ideas in the Review that have been accepted...
Partha Dasgupta
Nov 24, 2022
Impediments in Transitioning to Agile Time-boxing Testing Efforts
Taniya Dasgupta
Jan 01, 0001
In agile framework, the system is developed in sprints. Some value-based products for the customers are created with completion of work in a sprint. There are firm dates of commencement and end in sprints, and duration of each...
Agile Project Management Traditional Testing Efforts transition Methodology Management Information Systems
Published by: Harrisburg University of Science and Technology
Mergers and its Effects in Select Indian Iron and Steel Companies - A Study
Madhumita Dasgupta
Aug 31, 2022
As an important sphere of corporate strategy, Mergers and Acquisitions have been undergoing a sea change within the economic set -up since liberalization in India. Massive growth in both Foreign Direct Investment and Foreign...
Published by: Singh Publication
Population, Ecological Footprint and the Sustainable Development Goals.
The Anthropocene can be read as being the era when the demand humanity makes on the biosphere's goods and services-humanity's 'ecological footprint'-vastly exceeds its ability to supply it on a sustainable basis. Because the...
Dual role of nanoparticles as drug carrier and drug.
Hirak Kumar Patra, Anjan Kr Dasgupta, Sounik Sarkar, Indranil Biswas, Arnab Chattopadhyay
Jul 31, 2019
The conventional chemotherapeutic agents used in the treatment of human malignancies are directed nonspecifically against both malignant and nonmalignant cells, often limiting their efficacy with having serious side effects....
Mergers and its Effects in Select Indian Iron and Steel Companies - A Study
Madhumita Dasgupta
Aug 31, 2022
As an important sphere of corporate strategy, Mergers and Acquisitions have been undergoing a sea change within the economic set -up since liberalization in India. Massive growth in both Foreign Direct Investment and Foreign...
Published by: Singh Publication
Beyond a standardised urban lexicon
Urban vocabulary has been influenced by global patterns of modernity, capitalism and anglophone academia. These lexicons are increasingly standardised and shape dominant conceptual approaches in city debates. However...
Social dimensions of fertility behavior and consumption patterns in the Anthropocene.
Scott Barrett, Aisha Dasgupta, Partha Dasgupta, W Neil Adger, John Anderies, Jeroen van den Bergh, Caroline Bledsoe, John Bongaarts, Stephen Carpenter, F Stuart Chapin, Anne-Sophie Crépin, Gretchen Daily, Paul Ehrlich, Carl Folke, Nils Kautsky, Eric F Lambin, Simon A Levin, Karl-Göran Mäler, Rosamond Naylor, Karine Nyborg, Stephen Polasky, Marten Scheffer, Jason Shogren, Peter Søgaard Jørgensen, Brian Walker, James Wilen
Apr 13, 2020
We consider two aspects of the human enterprise that profoundly affect the global environment: population and consumption. We show that fertility and consumption behavior harbor a class of externalities that have not been much...
Dramatic response of metastatic cutaneous angiosarcoma to an immune checkpoint inhibitor in a patient with xeroderma pigmentosum
Sophie Momen, Hiva Fassihi, Helen R Davies, Christos Nikolaou, Andrea Degasperi, Catherine M Stefanato, Joao ML Dias, Dhruba Dasgupta, Emma Craythorne, Robert Sarkany, Sophie Papa, Serena Nik-Zainal
Nov 13, 2019
"Mutational signatures" are patterns of mutations that report DNA damage and subsequent repair processes that have occurred. Whole-genome sequencing (WGS) can provide additional information to standard diagnostic techniques and...
metastatic angiosarcoma Adult Antibodies Monoclonal Antibodies Monoclonal Humanized B7-H1 Antigen DNA Mutational Analysis DNA Polymerase II Hemangiosarcoma Humans Male Microsatellite Instability Mutation Poly-ADP-Ribose Binding Proteins Programmed Cell Death 1 Receptor Skin Neoplasms whole genome sequencing Xeroderma Pigmentosum
Targeting chondroitinase ABC to axons enhances the ability of chondroitinase to promote neurite outgrowth and sprouting
Priscilla Day, Nuno Alves, Esther Daniell, Debayan Dasgupta, Rosalie Ogborne, Ashley Steeper, Mansoor Raza, Clare Ellis, James Fawcett, Roger Keynes, Elizabeth Muir
Jan 21, 2020
Background: There is currently no effective treatment for promoting regeneration of injured nerves in patients who have sustained injury to the central nervous system such as spinal cord injury. Chondroitinase ABC is an enzyme...
Re-arranging the urban
A Abdullah, R Cardoso, S Dasgupta, S Pati, R Plueckhahn, T Shafique, AM Simone, SSK Teo, J Ye, Y Zhao
Mar 13, 2023
This intervention is by a collective of scholars working on various facets of urbanisation in Asia. Focusing on the notion of arrangements/re‐arrangements, it seeks to extend the consideration of urban politics as a matter of...
Targeting chondroitinase ABC to axons enhances the ability of chondroitinase to promote neurite outgrowth and sprouting.
Priscilla Day, Nuno Alves, Esther Daniell, Debayan Dasgupta, Rosalie Ogborne, Ashley Steeper, Mansoor Raza, Clare Ellis, James Fawcett, Roger Keynes, Elizabeth Muir
Feb 21, 2020
BACKGROUND:There is currently no effective treatment for promoting regeneration of injured nerves in patients who have sustained injury to the central nervous system such as spinal cord injury. Chondroitinase ABC is an enzyme...
Published by: PLOS ONE
Frontiers in Prebiotic Chemistry and Early Earth Environments.
Ulrich F Müller, Jamie Elsila, Dustin Trail, Saurja DasGupta, Claudia-Corina Giese, Craig R Walton, Zachary R Cohen, Tomislav Stolar, Ramanarayanan Krishnamurthy, Timothy W Lyons, Karyn L Rogers, Loren Dean Williams
Aug 07, 2022
The Prebiotic Chemistry and Early Earth Environments (PCE3) Consortium is a community of researchers seeking to understand the origins of life on Earth and in the universe. PCE3 is one of five Research Coordination Networks...
Trafficking and processing of bacterial proteins by mammalian cells
Elizabeth Muir, Mansoor Raza, Clare Ellis, Emily Burnside, Fiona Love, Simon Heller, Matthew Elliot, Esther Daniell, Debayan Dasgupta, Nuno Alves, Priscilla Day, James Fawcett, Roger Keynes
Feb 07, 2018
BACKGROUND: There is very little reported in the literature about the relationship between modifications of bacterial proteins and their secretion by mammalian cells that synthesize them. We previously reported that the...
Our future in the Anthropocene biosphere.
Carl Folke, Stephen Polasky, Johan Rockström, Victor Galaz, Frances Westley, Michèle Lamont, Marten Scheffer, Henrik Österblom, Stephen R Carpenter, F Stuart Chapin, Karen C Seto, Elke U Weber, Beatrice I Crona, Gretchen C Daily, Partha Dasgupta, Owen Gaffney, Line J Gordon, Holger Hoff, Simon A Levin, Jane Lubchenco, Will Steffen, Brian H Walker
Mar 22, 2021
Addressing our planetary crisis
Jim Falk, Faten Attig-Bahar, Rita R Colwell, Swadhin K Behera, Adel S El-Beltagy, Joachim von Braun, Partha Dasgupta, Peter H Gleick, Ryuichi Kaneko, Charles F Kennel, Phoebe Koundouri, Yuan Tseh Lee, Thomas E Lovejoy, Amy Luers, Cherry A Murray, Rattan Lal, Ismail Serageldin, Youba Sokona, Kazuhiko Takeuchi, Makoto Taniguchi, Chiho Watanabe, Tetsuzo Yasunari
Jan 07, 2022
Ruxolitinib-induced defects in DNA repair cause sensitivity to PARP inhibitors in myeloproliferative neoplasms.
Margaret Nieborowska-Skorska, Silvia Maifrede, Yashodhara Dasgupta, Katherine Sullivan, Sylwia Flis, Bac Viet Le, Martyna Solecka, Elizaveta A Belyaeva, Lucia Kubovcakova, Morgan Nawrocki, Martin Kirschner, Huaqing Zhao, Josef T Prchal, Katarzyna Piwocka, Alison R Moliterno, Mariusz Wasik, Steffen Koschmieder, Tony R Green, Radek C Skoda, Tomasz Skorski
May 31, 2018
Myeloproliferative neoplasms (MPNs) often carry JAK2(V617F), MPL(W515L), or CALR(del52) mutations. Current treatment options for MPNs include cytoreduction by hydroxyurea and JAK1/2 inhibition by ruxolitinib, both of which are...
Eligibility for clinical trials in primary Sjögren's syndrome
Clare Oni, Sheryl Mitchell, Katherine James, Wan-Fai Ng, Bridget Griffiths, Victoria Hindmarsh, Elizabeth Price, Colin T Pease, Paul Emery, Peter Lanyon, Adrian Jones, Michele Bombardieri, Nurhan Sutcliffe, Costantino Pitzalis, John Hunter, Monica Gupta, John McLaren, Annie Cooper, Marian Regan, Ian Giles, David Isenberg, Vadivelu Saravanan, David Coady, Bhaskar DasGupta, Neil McHugh, Steven Young-Min, Robert Moots, Nagui Gendi, Mohammed Akil, Francesca Barone, Ben Fisher, Saaeha Rauz, Andrea Richards, Simon J Bowman
Mar 01, 2016
OBJECTIVE: To identify numbers of participants in the UK Primary Sjögren's Syndrome Registry (UKPSSR) who would fulfil eligibility criteria for previous/current or potential clinical trials in primary SS (pSS) in order to...
Eligibility for clinical trials in primary Sjögren's syndrome
Clare Oni, Sheryl Mitchell, Katherine James, Wan-Fai Ng, Bridget Griffiths, Victoria Hindmarsh, Elizabeth Price, Colin T Pease, Paul Emery, Peter Lanyon, Adrian Jones, Michele Bombardieri, Nurhan Sutcliffe, Costantino Pitzalis, John Hunter, Monica Gupta, John McLaren, Annie Cooper, Marian Regan, Ian Giles, David Isenberg, Vadivelu Saravanan, David Coady, Bhaskar DasGupta, Neil McHugh, Steven Young-Min, Robert Moots, Nagui Gendi, Mohammed Akil, Francesca Barone, Ben Fisher, Saaeha Rauz, Andrea Richards, Simon J Bowman
Mar 01, 2016
OBJECTIVE: To identify numbers of participants in the UK Primary Sjögren's Syndrome Registry (UKPSSR) who would fulfil eligibility criteria for previous/current or potential clinical trials in primary SS (pSS) in order to...
A Transcriptional Signature of Fatigue Derived from Patients with Primary Sjögren's Syndrome
Katherine James, Shereen Al-Ali, Jessica Tarn, Simon J Cockell, Colin S Gillespie, Victoria Hindmarsh, James Locke, Sheryl Mitchell, Dennis Lendrem, Simon Bowman, Elizabeth Price, Colin T Pease, Paul Emery, Peter Lanyon, John A Hunter, Monica Gupta, Michele Bombardieri, Nurhan Sutcliffe, Costantino Pitzalis, John McLaren, Annie Cooper, Marian Regan, Ian Giles, David Isenberg, Vadivelu Saravanan, David Coady, Bhaskar DasGupta, Neil McHugh, Steven Young-Min, Robert Moots, Nagui Gendi, Mohammed Akil, Bridget Griffiths, Anil Wipat, Julia Newton, David E Jones, John Isaacs, Jennifer Hallinan, Wan-Fai Ng
Jan 01, 0001
BACKGROUND: Fatigue is a debilitating condition with a significant impact on patients' quality of life. Fatigue is frequently reported by patients suffering from primary Sjögren's Syndrome (pSS), a chronic autoimmune...
The 2022 Europe report of the Lancet Countdown on health and climate change
Kim R van Daalen, Marina Romanello, Joacim Rocklöv, Jan C Semenza, Cathryn Tonne, Anil Markandya, Niheer Dasandi, Slava Jankin, Hicham Achebak, Joan Ballester, Hannah Bechara, Max W Callaghan, Jonathan Chambers, Shouro Dasgupta, Paul Drummond, Zia Farooq, Olga Gasparyan, Nube Gonzalez-Reviriego, Ian Hamilton, Risto Hänninen, Aleksandra Kazmierczak, Vladimir Kendrovski, Harry Kennard, Gregor Kiesewetter, Simon J Lloyd, Martin Lotto Batista, Jaime Martinez-Urtaza, Carles Milà, Jan C Minx, Mark Nieuwenhuijsen, Julia Palamarchuk, Marcos Quijal-Zamorano, Elizabeth JZ Robinson, Daniel Scamman, Oliver Schmoll, Maquins Odhiambo Sewe, Henrik Sjödin, Mikhail Sofiev, Balakrishnan Solaraju-Murali, Marco Springmann, Joaquin Triñanes, Josep M Anto, Maria Nilsson, Rachel Lowe
Nov 28, 2022
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