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Eukaryotic Transcriptional Activation Mechanism: Protein-Protein Interactions
Tae Kook Kim
Jan 01, 0001
Various in vivo and in vitro assays have been employed to analyze how activators communicate with the general transcription machinery to stimulate transcription. As a first step, I analyzed the function of distinct kinds of...
Published by: Rockefeller University
Ensuring Core Competencies for Cybersecurity Specialists
Within an organization, it is critical that all employees possess a security awareness and thus play a part in the protection of said organization's information assets. Some employees will have key roles and responsibilities and...
Published by: IGI Global Scientific Publishing
Vitamin D3 Supplementation Reduces the Symptoms of Upper Respiratory Tract Infection during Winter Training in Vitamin D-Insufficient Taekwondo Athletes
Vitamin D insufficiency may be associated with increased risk of upper respiratory tract infection (URTI) in athletes. This study examined the effects of vitamin D3 supplementation on salivary immune functions and symptoms of...
high-intensity training respiratory immune function secretory immunoglobulin vitamin D Exercise Science Kinesiology
Published by: Digital Commons @ Texas A&M University-San Antonio
Vitamin D3 Supplementation Reduces the Symptoms of Upper Respiratory Tract Infection during Winter Training in Vitamin D-Insufficient Taekwondo Athletes
Vitamin D insufficiency may be associated with increased risk of upper respiratory tract infection (URTI) in athletes. This study examined the effects of vitamin D3 supplementation on salivary immune functions and symptoms of...
high-intensity training respiratory immune function secretory immunoglobulin vitamin D Exercise Science Kinesiology
Published by: Digital Commons @ Texas A&M University-San Antonio
Vitamin D3 Supplementation Reduces the Symptoms of Upper Respiratory Tract Infection during Winter Training in Vitamin D-Insufficient Taekwondo Athletes
Vitamin D insufficiency may be associated with increased risk of upper respiratory tract infection (URTI) in athletes. This study examined the effects of vitamin D3 supplementation on salivary immune functions and symptoms of...
high-intensity training respiratory immune function secretory immunoglobulin vitamin D Exercise Science Kinesiology
Published by: Digital Commons @ Texas A&M University-San Antonio
The IKKbeta subunit of IkappaB kinase (IKK) is essential for nuclear factor kappaB activation and prevention of apoptosis.
The IkappaB kinase (IKK) complex is composed of three subunits, IKKalpha, IKKbeta, and IKKgamma (NEMO). While IKKalpha and IKKbeta are highly similar catalytic subunits, both capable of IkappaB phosphorylation in vitro, IKKgamma...
Concentration-Dependent Activity of Hydromethylthionine on Clinical Decline and Brain Atrophy in a Randomized Controlled Trial in Behavioral Variant Frontotemporal Dementia.
Helen Shiells, Bjoern O Schelter, Peter Bentham, Thomas C Baddeley, Christopher M Rubino, Harish Ganesan, Jeffrey Hammel, Vesna Vuksanovic, Roger T Staff, Alison D Murray, Luc Bracoud, Damon J Wischik, Gernot Riedel, Serge Gauthier, Jianping Jia, Hans J Moebius, Jiri Hardlund, Christopher M Kipps, Karin Kook, John MD Storey, Charles R Harrington, Claude M Wischik
Oct 09, 2020
BACKGROUND: Hydromethylthionine is a potent inhibitor of pathological aggregation of tau and TDP-43 proteins. OBJECTIVE: To compare hydromethylthionine treatment effects at two doses and to determine how drug exposure is related...
Behavioral variant frontotemporal dementia TDP-43 Clinical Trials hydromethylthionine leucomethylthioninium Tau protein Adult Aged Atrophy Brain Disease Progression Dose-Response Relationship Drug Double-Blind Method Female frontotemporal dementia Humans Magnetic Resonance Imaging Male Methylene blue Middle Aged Treatment Outcome
Musicians’ views on the role of reading music in learning, performance, and understanding
Reading music notation is not an easy skill to acquire and can take years of training to master. In addition, it is not strictly necessary to be able to read music to make music. Nevertheless, music teaching and learning in the...
Citizen Adoption in E-Government Systems
Electronic Government (e-Government) refers to a system of information, communication and interaction between government and its citizens. E-Government adoption has been studied for more than a decade with several meta-analytic...
Published by: IGI Global Scientific Publishing
Non-smooth Hopf-type bifurcations arising from impact–friction contact events in rotating machinery
We analyse the novel dynamics arising in a nonlinear rotor dynamic system by investigating the discontinuity-induced bifurcations corresponding to collisions with the rotor housing (touchdown bearing surface interactions). The...
Surveillance recommendations for DICER1 pathogenic variant carriers
Jette J Bakhuizen, Helen Hanson, Karin van der Tuin, Fiona Lalloo, Marc Tischkowitz, Karin Wadt, Marjolijn CJ Jongmans, SIOPE Host Genome Working Group, CanGene-CanVar Clinical Guideline Working Group, Expert Network Members
Oct 01, 2021
DICER1 syndrome is a rare genetic disorder that predisposes to a wide spectrum of tumors. Developing surveillance protocols for this syndrome is challenging because uncertainty exists about the clinical efficacy of surveillance...
Relations between the Sizes of Galaxies and Their Dark Matter Halos at Redshifts 0 <z <3
Kuang Han Huang, S. Michael Fall, Henry C. Ferguson, Arjen van der Wel, Norman Grogin, Anton Koekemoer, Seong-Kook Lee, Pablo G. Pérez-González, Stijn Wuyts
Mar 17, 2017
We derive relations between the effective radii R eff of galaxies and the virial radii R 200c of their dark matter halos over the redshift range 0 <z <3. For galaxies, we use the measured sizes...
Hearing where the eyes see
To reduce sensory uncertainty, humans combine cues from multiple senses. However, in everyday life, many co‐occurring cues are irrelevant to the task at hand. How do humans know which cues to ignore? And does this ability change...
The Effects of Explicit and Implicit Cognitive Factors on the Learning Patterns in the Iowa Gambling Task
The Iowa Gambling Task (IGT) has become a standard tool in the area of decision making, but recent studies have indicated that cognitive factors might distort the implicit learning expected from the original design of the task....
Published by: Digital Commons @ Texas A&M University-San Antonio
High Trait Anxiety Enhances Optimal Integration of Auditory and Visual Threat Cues
Background
Emotion perception is essential to human interaction and relies on effective integration of emotional cues across sensory modalities. Despite initial evidence for anxiety-related biases in multisensory...
Emotion perception is essential to human interaction and relies on effective integration of emotional cues across sensory modalities. Despite initial evidence for anxiety-related biases in multisensory...
Anxiety emotion maximum likelihood estimation Multisensory processing negative bias race model /dk/atira/pure/subjectarea/asjc/3200/3205 name=Experimental and Cognitive Psychology /dk/atira/pure/subjectarea/asjc/1200/1201 name=Arts and Humanities (miscellaneous) /dk/atira/pure/subjectarea/asjc/3200/3203 name=Clinical Psychology /dk/atira/pure/subjectarea/asjc/2700/2738 name=Psychiatry and Mental health /dk/atira/pure/sustainabledevelopmentgoals/good_health_and_well_being name=SDG 3 - Good Health and Well-being
Relations between the Sizes of Galaxies and Their Dark Matter Halos at Redshifts 0 <z <3
Kuang Han Huang, S. Michael Fall, Henry C. Ferguson, Arjen van der Wel, Norman Grogin, Anton Koekemoer, Seong-Kook Lee, Pablo G. Pérez-González, Stijn Wuyts
Mar 17, 2017
We derive relations between the effective radii R eff of galaxies and the virial radii R 200c of their dark matter halos over the redshift range 0 <z <3. For galaxies, we use the measured sizes...
Human autoantibodies against the 54 kDa protein of the signal recognition particle block function at multiple stages.
Non-smooth Hopf-type bifurcations arising from impact–friction contact events in rotating machinery
We analyse the novel dynamics arising in a nonlinear rotor dynamic system by investigating the discontinuity-induced bifurcations corresponding to collisions with the rotor housing (touchdown bearing surface interactions). The...
Three ancient hormonal cues co-ordinate shoot branching in a moss.
Yoan Coudert, Wojtek Palubicki, Karin Ljung, Ondrej Novak, Ottoline Leyser, C Jill Harrison
Jun 26, 2015
Physcomitrella apical dominance branching developmental biology gametophyte plant biology Stem Cells Biological Transport Body Patterning Bryopsida Cytokinins Gene Expression Regulation Plant Indoleacetic Acids Lactones Models Biological Morphogenesis Mutation Plant Epidermis Plant Growth Regulators Plant Proteins Plant Shoots Plants Genetically Modified
Experience in judging intent to harm modulates parahippocampal activity
Does visual experience in judging intent to harm change our brain responses? And if it does, what are the mechanisms affected? We addressed these questions by studying the abilities of Closed Circuit Television (CCTV) operators...
A Comparison of the Representation of Women in Editor Positions at Major Medical Journals in 2021 vs 2011.
Christina Starchl, Vianca Shah, Ines Zollner-Schwetz, Jovana Knezevic, Simon Geiger, Karin Amrein
Jan 27, 2023
PURPOSE: There continues to be a disparity in the representation of women across medicine, including in editor positions at major medical journals. The authors repeated a study they had conducted in 2011 to compare the...
Musicians’ views on the role of reading music in learning, performance, and understanding
Reading music notation is not an easy skill to acquire and can take years of training to master. In addition, it is not strictly necessary to be able to read music to make music. Nevertheless, music teaching and learning in the...
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