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Results: 105
Amino acid variants of SARS-CoV-2 papain-like protease have impact on drug binding.
Agata P Perlinska, Adam Stasiulewicz, Mai Lan Nguyen, Karolina Swiderska, Mikolaj Zmudzinski, Alicja W Maksymiuk, Marcin Drag, Joanna I Sulkowska
Dec 08, 2022
The novel severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) has caused both a health and economic crisis around the world. Its papain-like protease (PLpro) is one of the protein targets utilized in designing new drugs...
Amino acid variants of SARS-CoV-2 papain-like protease have impact on drug binding.
Agata P Perlinska, Adam Stasiulewicz, Mai Lan Nguyen, Karolina Swiderska, Mikolaj Zmudzinski, Alicja W Maksymiuk, Marcin Drag, Joanna I Sulkowska
Dec 22, 2022
The novel severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) has caused both a health and economic crisis around the world. Its papain-like protease (PLpro) is one of the protein targets utilized in designing new drugs...
The Geology of the Middle Cam Valley, Cambridgeshire, UK
This study offers a new understanding of the stratigraphy and context of the Pleistocene (including Elsterian and Weichselian) and Holocene deposits of the Middle Cam valley, Cambridgeshire, United Kingdom, and provides...
Doping Engineering of Single-Walled Carbon Nanotubes by Nitrogen Compounds Using Basicity and Alignment.
Bogumiła Kumanek, Karolina Z Milowska, Łukasz Przypis, Grzegorz Stando, Karolina Matuszek, Douglas MacFarlane, Mike C Payne, Dawid Janas
Jun 29, 2022
Charge transport properties in single-walled carbon nanotubes (SWCNTs) can be significantly modified through doping, tuning their electrical and thermoelectric properties. In our study, we used more than 40 nitrogen-bearing...
Solving the wave equation with multifrequency oscillations
We explore a new asymptotic-numerical solver for the time-dependent wave equation with an interaction term that is oscillating in time with a very high frequency. The method involves representing the solution as an asymptotic...
Enhancing thermoelectric properties of single-walled carbon nanotubes using halide compounds at room temperature and above
Bogumiła Kumanek, Grzegorz Stando, Paweł Stando, Karolina Matuszek, Karolina Z. Milowska, Maciej Krzywiecki, Marta Gryglas-Borysiewicz, Zuzanna Ogorzałek, Mike C. Payne, Douglas MacFarlane, Dawid Janas
Apr 21, 2021
Abstract: Carbon nanotubes (CNTs) are materials with exceptional electrical, thermal, mechanical, and optical properties. Ever since it was demonstrated that they also possess interesting thermoelectric properties, they have...
<em>Homo homini lupus</em>? Explaining antisocial punishment
Punishing group members who parasitize their own group’s resources is an almost universal human behavior, as evidenced by multiple cross-cultural and theoretical studies. Recently, researchers in social and behavioral sciences...
Revisiting the Impact of Local Leptin Signaling in Folliculogenesis and Oocyte Maturation in Obese Mothers.
The complex nature of folliculogenesis regulation accounts for its susceptibility to maternal physiological fitness. In obese mothers, progressive expansion of adipose tissue culminates with severe hyperestrogenism and...
Enhancing thermoelectric properties of single-walled carbon nanotubes using halide compounds at room temperature and above.
Bogumiła Kumanek, Grzegorz Stando, Paweł Stando, Karolina Matuszek, Karolina Z Milowska, Maciej Krzywiecki, Marta Gryglas-Borysiewicz, Zuzanna Ogorzałek, Mike C Payne, Douglas MacFarlane, Dawid Janas
Apr 26, 2021
Carbon nanotubes (CNTs) are materials with exceptional electrical, thermal, mechanical, and optical properties. Ever since it was demonstrated that they also possess interesting thermoelectric properties, they have been...
Revisiting the Impact of Local Leptin Signaling in Folliculogenesis and Oocyte Maturation in Obese Mothers
The complex nature of folliculogenesis regulation accounts for its susceptibility to maternal physiological fitness. In obese mothers, progressive expansion of adipose tissue culminates with severe hyperestrogenism and...
<em>Homo homini lupus</em>? Explaining antisocial punishment
Punishing group members who parasitize their own group’s resources is an almost universal human behavior, as evidenced by multiple cross-cultural and theoretical studies. Recently, researchers in social and behavioral sciences...
Visual identifier systems for patients with cognitive impairment in healthcare settings
Abstract: Background: People with dementia and other forms of cognitive impairment form a substantial proportion of patients admitted to hospitals, but problems in their care are persistent. One widely proposed improvement...
Original Article COGNITIVE IMPAIRMENT Dementia hospital care identification Patient Care person‐centred care Survey
Published by: International Journal of Older People Nursing
Effective Approximation for the Semiclassical Schrödinger Equation
The computation of the semiclassical Schrödinger equation presents major challenges because of the presence of a small parameter. Assuming periodic boundary conditions, the standard approach consists of semi-discretisation...
Exponential splittings Krylov subspace methods Semiclassical Schrödinger equation Spectral collocation Zassenhaus splitting /dk/atira/pure/subjectarea/asjc/2600/2603 name=Analysis /dk/atira/pure/subjectarea/asjc/2600/2605 name=Computational Mathematics /dk/atira/pure/subjectarea/asjc/1700/1703 name=Computational Theory and Mathematics /dk/atira/pure/subjectarea/asjc/2600/2604 name=Applied Mathematics
Solving the wave equation with multifrequency oscillations
We explore a new asymptotic-numerical solver for the time-dependent wave equation with an interaction term that is oscillating in time with a very high frequency. The method involves representing the solution as an asymptotic...
Effective Approximation for the Semiclassical Schrödinger Equation
The computation of the semiclassical Schrödinger equation presents major challenges because of the presence of a small parameter. Assuming periodic boundary conditions, the standard approach consists of semi-discretisation...
Exponential splittings Krylov subspace methods Semiclassical Schrödinger equation Spectral collocation Zassenhaus splitting /dk/atira/pure/subjectarea/asjc/2600/2603 name=Analysis /dk/atira/pure/subjectarea/asjc/2600/2605 name=Computational Mathematics /dk/atira/pure/subjectarea/asjc/1700/1703 name=Computational Theory and Mathematics /dk/atira/pure/subjectarea/asjc/2600/2604 name=Applied Mathematics
Serious physical assault and subsequent risk for rehospitalization in individuals with severe mental illness
Abstract: Background: Victimization is associated with worse social and clinical outcomes of individuals with severe mental illness (SMI). A relapse of SMI may be one of the clinical consequences of assaultive trauma. As far as...
Will the making of plasmacytoid dendritic cells in vitro help unravel their mysteries?
[No abstract available]
Published by: Rockefeller University
Regionalization of the mouse visceral endoderm as the blastocyst transforms into the egg cylinder.
Aitana Perea-Gomez, Sigolène M Meilhac, Karolina Piotrowska-Nitsche, Dionne Gray, Jérôme Collignon, Magdalena Zernicka-Goetz
Jun 14, 2011
Effective Communication Following Pregnancy Loss
Louise Austin, Jeannette Littlemore, Sheelagh McGuinness, Sarah Turner, Danielle Fuller, Karolina Kuberska
Oct 15, 2020
Each year in the UK there are approximately 250,000 miscarriages, 3,000 stillbirths and 3,000 terminations following a diagnosis of fetal-abnormality. This paper draws from original empirical research into the experience of...
Serious physical assault and subsequent risk for rehospitalization in individuals with severe mental illness
BACKGROUND: Victimization is associated with worse social and clinical outcomes of individuals with severe mental illness (SMI). A relapse of SMI may be one of the clinical consequences of assaultive trauma. As far as we know...
R.ROSETTA
Mateusz Garbulowski, Klev Diamanti, Karolina Smolińska, Nicholas Baltzer, Patricia Stoll, Susanne Bornelöv, Aleksander Øhrn, Lars Feuk, Jan Komorowski
Mar 07, 2021
Efficient Magnus-type integrators for solar energy conversion in Hubbard models
Winfried Auzinger, Juliette Dubois, Karsten Held, Harald Hofstätter, Tobias Jawecki, Anna Kauch, Othmar Koch, Karolina Kropielnicka, Pranav Singh, Clemens Watzenböck
Jan 31, 2022
Strongly interacting electrons in solids are generically described by Hubbardtype models, and the impact of solar light can be modeled by an additional time-dependence. This yields a finite dimensional system of ordinary...
Keep nice and carry on
Olga Bialobrzeska, Justyna Baba, Sylwia Bedynska, Aleksandra Cichocka, Aleksandra Cislak, Magdalena Formanowicz, Gosia Goclowska, Zuzanna Jakubik, Karolina Kozakiewicz
Dec 31, 2023
Practicing acts of kindness is beneficial to one’s well-being, but is simply being nice to others also beneficial? In a correlational Study 1 (N=497), self-reported behavioral niceness was positively correlated with happiness...
Leptin Signaling in the Ovary of Diet-Induced Obese Mice Regulates Activation of NOD-Like Receptor Protein 3 Inflammasome.
Marek Adamowski, Karolina Wołodko, Joana Oliveira, Juan Castillo-Fernandez, Daniel Murta, Gavin Kelsey, António M Galvão
Nov 22, 2021
Obesity leads to ovarian dysfunction and the establishment of local leptin resistance. The aim of our study was to characterize the levels of NOD-like receptor protein 3 (NLRP3) inflammasome activation in ovaries and liver of...
Efficient Magnus-type integrators for solar energy conversion in Hubbard models
Winfried Auzinger, Juliette Dubois, Karsten Held, Harald Hofstätter, Tobias Jawecki, Anna Kauch, Othmar Koch, Karolina Kropielnicka, Pranav Singh, Clemens Watzenböck
Jan 31, 2022
Strongly interacting electrons in solids are generically described by Hubbardtype models, and the impact of solar light can be modeled by an additional time-dependence. This yields a finite dimensional system of ordinary...
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