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Prospective Assessment of Tumour Burden and Bone Disease in Plasma Cell Dyscrasias Using DW-MRI and Exploratory Bone Biomarkers.
Gaurav Agarwal, Guido Nador, Sherin Varghese, Hiwot Getu, Charlotte Palmer, Edmund Watson, Claudio Pereira, Germana Sallemi, Karen Partington, Neel Patel, Rajkumar Soundarajan, Rebecca Mills, Richard Brouwer, Marina Maritati, Aarti Shah, Delia Peppercorn, Udo Oppermann, Claire M Edwards, Christopher T Rodgers, Muhammad Kassim Javaid, Sarah Gooding, Karthik Ramasamy
Feb 09, 2023
Maximizing Operational Efficiency in Healthcare
Private equity investment in the healthcare sector has emerged as a powerful tool for growth and development. Healthcare organizations are increasingly turning to PE investors for strategic, operational, and financial expertise...
Published by: IGI Global Scientific Publishing
An RF Approach to Modelling Gallium Nitride Power Devices Using Parasitic Extraction
This paper begins with a comprehensive review into the existing GaN device models. Secondly, it identifies the need for a more accurate GaN switching model. A simple practical process based on radio frequency techniques...
Prospective Assessment of Tumour Burden and Bone Disease in Plasma Cell Dyscrasias Using DW-MRI and Exploratory Bone Biomarkers
Gaurav Agarwal, Guido Nador, Sherin Varghese, Hiwot Getu, Charlotte Palmer, Edmund Watson, Claudio Pereira, Germana Sallemi, Karen Partington, Neel Patel, Rajkumar Soundarajan, Rebecca Mills, Richard Brouwer, Marina Maritati, Aarti Shah, Delia Peppercorn, Udo Oppermann, Claire M Edwards, Christopher T Rodgers, Muhammad Kassim Javaid, Sarah Gooding, Karthik Ramasamy
Jan 04, 2023
Risk and response adapted therapy following autologous stem cell transplant in patients with newly diagnosed multiple myeloma (RADAR (UK-MRA Myeloma XV Trial)
Kara-Louise Royle, Amy Beth Coulson, Karthik Ramasamy, David A Cairns, Anna Hockaday, Sergio Quezada, Mark Drayson, Martin Kaiser, Roger Owen, Holger W Auner, Gordon Cook, David Meads, Catherine Olivier, Lorna Barnard, Rhiannon Lambkin, Andrea Paterson, Bryony Dawkins, Mike Chapman, Guy Pratt, Rakesh Popat, Graham Jackson, Ceri Bygrave, Jonathan Sive, Ruth de Tute, Andrew Chantry, Christopher Parrish, Mark Cook, Samir Asher, Kwee Yong
Dec 18, 2022
INTRODUCTION: Multiple myeloma is a plasma cell malignancy that accounts for 1%-2% of newly diagnosed cancers.At diagnosis, approximately 20% of patients can be identified, using cytogenetics, to have inferior survival...
CANCER GENETICS Clinical Trials myeloma Protocols & guidelines statistics & research methods Humans multiple myeloma Transplantation Autologous Hematopoietic Stem Cell Transplantation Stem Cell Transplantation neoplasm Residual United Kingdom Randomized Controlled Trials as Topic Multicenter Studies as Topic Clinical Trials Phase II as Topic
Strategies for Conditional Regulation of Proteins.
Karthik Nadendla, Grant G Simpson, Julie Becher, Toby Journeaux, Mar Cabeza-Cabrerizo, Gonçalo JL Bernardes
Feb 28, 2023
Design of the next-generation of therapeutics, biosensors, and molecular tools for basic research requires that we bring protein activity under control. Each protein has unique properties, and therefore, it is critical to tailor...
Anti-VEGF intervention in neovascular AMD
OBJECTIVE: Clear information is essential to properly determine preference in medical intervention. In neovascular age-related macular degeneration, patients need to understand the balance of risk and benefit of anti-vascular...
Risk and response adapted therapy following autologous stem cell transplant in patients with newly diagnosed multiple myeloma (RADAR (UK-MRA Myeloma XV Trial)
Kara-Louise Royle, Amy Beth Coulson, Karthik Ramasamy, David A Cairns, Anna Hockaday, Sergio Quezada, Mark Drayson, Martin Kaiser, Roger Owen, Holger W Auner, Gordon Cook, David Meads, Catherine Olivier, Lorna Barnard, Rhiannon Lambkin, Andrea Paterson, Bryony Dawkins, Mike Chapman, Guy Pratt, Rakesh Popat, Graham Jackson, Ceri Bygrave, Jonathan Sive, Ruth de Tute, Andrew Chantry, Christopher Parrish, Mark Cook, Samir Asher, Kwee Yong
Nov 22, 2022
Population genomics reveals that an anthropophilic population of $\textit{Aedes aegypti}$ mosquitoes in West Africa recently gave rise to American and Asian populations of this major disease vector
JE Crawford, JM Alves, WJ Palmer, JP Day, M Sylla, R Ramasamy, SN Surendran, WC Black, A Pain, FM Jiggins
May 05, 2017
Functionalized graphene oxide tablets for sample preparation of drugs in biological fluids
Zeynab Zohdijamil, Mahdi Hashemi, Abbi Abdel-Rehim, Karthik Laxman, Abdusalam Uheida, Joydeep Dutta, Mohamed Abdel-Rehim
Jun 04, 2021
In this work, graphene oxide-based tablets (GO-Tabs) were prepared by applying a thin layer of functionalized GO on a polyethylene substrate. The GO was functionalized with amine groups (-NH2 ) by poly(ethylene...
Diffusion MRI approaches for investigating microstructural complexity in a rat model of traumatic brain injury.
Karthik Chary, Eppu Manninen, Jade Claessens, Alonso Ramirez-Manzanares, Olli Gröhn, Alejandra Sierra
Feb 09, 2023
Our study explores the potential of conventional and advanced diffusion MRI techniques including diffusion tensor imaging (DTI), and single-shell 3-tissue constrained spherical deconvolution (SS3T-CSD) to investigate complex...
A Service Architecture Using Machine Learning to Contextualize Anomaly Detection
This article introduces a service that helps provide context and an explanation for the outlier score given to any network flow record selected by the analyst. The authors propose a service architecture for the delivery of...
Published by: IGI Global Scientific Publishing
Fuzzy Drug Targets
Suman Saurabh, Karthik Nadendla, Shubh Sanket Purohit, Ponnurengam Malliappan Sivakumar, Sibel Cetinel
Apr 17, 2023
Intrinsically disordered proteins (IDPs) and regions (IDRs) form a large part of the eukaryotic proteome. Contrary to the structure-function paradigm, the disordered proteins perform a myriad of functions in vivo. Consequently...
Inhibition of proteasome rescues a pathogenic variant of respiratory chain assembly factor COA7.
Evaluation of Factors Affecting Job Satisfaction Pathways for Improved Sustainable Business Performance in Emerging Economies
Job satisfaction is one of the vital needs of almost every employee in any well-structured organization. Any shortfall in the anticipated level of employee job satisfaction would affect the employees' contribution to...
Published by: IGI Global Scientific Publishing
Time-Series Forecasting and Analysis of COVID-19 Outbreak in Highly Populated Countries
A novel corona virus, COVID-19 is spreading across different countries in an alarming proportion and it has become a major threat to the existence of human community. With more than eight lakh death count within a very short...
Published by: IGI Global Scientific Publishing
Event-Based Social Networking System With Recommendation Engine
For over a decade, social networking has been ruling over the internet and plays a vital role in day-to-day life. However, for a new network to survive in this market, exclusivity is a necessity. As a result, the goal of this...
Published by: IGI Global Scientific Publishing
Population genomics reveals that an anthropophilic population of $\textit{Aedes aegypti}$ mosquitoes in West Africa recently gave rise to American and Asian populations of this major disease vector
JE Crawford, JM Alves, WJ Palmer, Jonathan Day, M Sylla, R Ramasamy, SN Surendran, WC Black, A Pain, Francis Jiggins
Apr 03, 2017
Content-Based Image Retrieval Using Hybrid Densenet121-Bilstm and Harris Hawks Optimization Algorithm
In the field of digital data management, content-based image retrieval (CBIR) has become one of the most important research areas, and it is used in many fields. This system searches a database of images to retrieve most...
Systems & Software Design Computer Science and Information Technology Systems and Software Engineering
Published by: IGI Global Scientific Publishing
Strategies for Conditional Regulation of Proteins.
Karthik Nadendla, Grant G Simpson, Julie Becher, Toby Journeaux, Mar Cabeza-Cabrerizo, Gonçalo J L Bernardes
Apr 05, 2023
Design of the next-generation of therapeutics, biosensors, and molecular tools for basic research requires that we bring protein activity under control. Each protein has unique properties, and therefore, it is critical to tailor...
Published by: JACS Au
Bias polarization study of steam electrolysis by composite oxygen electrode Ba<sub>0.5</sub>Sr<sub>0.5</sub>Co<sub>0.8</sub>Fe<sub>0.2</sub>O<sub>3-δ</sub>/BaCe<sub>0.4</sub>Zr<sub>0.4</sub>Y<sub>0.2</sub>O<sub>3-δ</sub>
Tao Yang, Aliaksandr Shaula, D. Pukazhselvan, Devaraj Ramasamy, Jiguang Deng, E. L. da Silva, Ricardo Duarte, Jorge A. Saraiva
Dec 01, 2017
The polarization behavior of Ba0.5Sr0.5Co0.8Fe0.2O3-δ-BaCe0.4Zr0.4Y0.2O3-δ (BSCF-BCZY) electrode under steam electrolysis...
Bias polarization study of steam electrolysis by composite oxygen electrode Ba<sub>0.5</sub>Sr<sub>0.5</sub>Co<sub>0.8</sub>Fe<sub>0.2</sub>O<sub>3-δ</sub>/BaCe<sub>0.4</sub>Zr<sub>0.4</sub>Y<sub>0.2</sub>O<sub>3-δ</sub>
Tao Yang, Aliaksandr Shaula, D. Pukazhselvan, Devaraj Ramasamy, Jiguang Deng, E. L. da Silva, Ricardo Duarte, Jorge A. Saraiva
Dec 01, 2017
The polarization behavior of Ba0.5Sr0.5Co0.8Fe0.2O3-δ-BaCe0.4Zr0.4Y0.2O3-δ (BSCF-BCZY) electrode under steam electrolysis...
Maternal antecedents of adiposity and studying the transgenerational role of hyperglycemia and insulin (MAASTHI): a prospective cohort study
Giridhara R Babu, Gvs Murthy, R Deepa, Yamuna, Prafulla, H Kiran Kumar, Maithili Karthik, Keerti Deshpande, Sara E Benjamin Neelon, D Prabhakaran, Anura Kurpad, Sanjay Kinra
Jan 10, 2018
BACKGROUND: India is experiencing an epidemic of obesity-hyperglycaemia, which coincides with child bearing age for women. The epidemic can be sustained and augmented through transgenerational transmission of adiposity and...
Birth cohort Gestational diabetes Hyperglycemia Lifecourse epidemiology obesity Protocol Adiposity Adult Birth Weight Blood Glucose Child Preschool Clinical Protocols Female Humans Hyperglycemia india Infant Infant Newborn Insulin Male Maternal Nutritional Physiological Phenomena obesity Pilot Projects Pregnancy Pregnancy Complications prenatal exposure delayed effects Prospective Studies Risk Factors Skinfold Thickness
Hydrodynamic voltammetry at a rocking disc electrode
Sunyhik D. Ahn, Karthik Somasundaram, H. Viet Nguyen, Erik Birgersson, Jim Yang Lee, Xiangming Gao, Adrian C. Fisher, Paul E. Frith, Frank Marken
Jan 10, 2016
Rocking disc electrode voltammetry (RoDE) is introduced as an experimentally convenient and versatile alternative to rotating disc voltammetry. A 1.6 mm diameter disc electrode is employed with an overall rocking angle of θ =...
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