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Results: 26
Proton magnetic resonance spectroscopy in frontotemporal lobar degeneration-related syndromes.
Alexander G Murley, Kamen A Tsvetanov, Matthew A Rouse, P Simon Jones, Katrine Sværke, Win Li, Adrian Carpenter, James B Rowe
Nov 19, 2021
There is an urgent need for a better understanding of the pathophysiology of cognitive impairment in syndromes associated with frontotemporal lobar degeneration. Here, we used magnetic resonance spectroscopy to quantify...
Behavioral variant frontotemporal dementia Corticobasal syndrome Frontotemporal Lobar Degeneration Glutamate progressive supranuclear palsy spectroscopy Aged Aspartic Acid Behavior Cognition Executive Function Female Frontotemporal Lobar Degeneration Glutamates Humans Male Middle Aged Prefrontal Cortex Primary visual cortex Proton Magnetic Resonance Spectroscopy Temporal Lobe
Magnetoelastic coupling in the cobalt adipate metal–organic framework from quasi-harmonic lattice dynamics
Magnetic interactions in hybrid materials are poorly understood compared to those in purely inorganic materials. The high flexibility of many metal–organic systems introduces a strong temperature dependence of the magnetic...
Performance of the ImmuView and BinaxNOW assays for the detection of urine and cerebrospinal fluid Streptococcus pneumoniae and Legionella pneumophila serogroup 1 antigen in patients with Legionnaires' disease or pneumococcal pneumonia and meningitis.
The performances of the ImmuView Streptococcus pneumoniae (Sp) and Legionella pneumophila (Lp) urinary antigen test were compared to that of the BinaxNOW Sp and Lp assays, using frozen urine from 166 patients with Legionnaires'...
The nature of UK supermarkets' policies on checkout food and associations with healthfulness and type of food displayed
BACKGROUND: Food choices are often determined by stimuli from our immediate surroundings, including strategic placement in shops to encourage impulse purchases. One example of this is food in shop checkout areas. Recently a...
Magnetoelastic coupling in the cobalt adipate metal–organic framework from quasi-harmonic lattice dynamics
Magnetic interactions in hybrid materials are poorly understood compared to those in purely inorganic materials. The high flexibility of many metal–organic systems introduces a strong temperature dependence of the magnetic...
Microscopic origin of entropy-driven polymorphism in hybrid organic-inorganic perovskite materials
Entropy is a critical, but often overlooked, factor in determining the relative stabilities of crystal phases. The importance of entropy is most pronounced in softer materials, where small changes in free energy can drive...
Free Energy of Ligand Removal in the Metal-Organic Framework UiO-66
Jessica Bristow, Katrine Svane, Davide Tiana, Jonathan Skelton, Julian D. Gale, Aron Walsh
May 05, 2016
We report an investigation of the `missing-linker phenomenon' in the Zr-based metal-organic framework UiO-66 using atomistic forcefield and quantum chemical methods. For a vacant benzene dicarboxylate ligand, the lowest energy...
Microscopic origin of entropy-driven polymorphism in hybrid organic-inorganic perovskite materials
Entropy is a critical, but often overlooked, factor in determining the relative stabilities of crystal phases. The importance of entropy is most pronounced in softer materials, where small changes in free energy can drive...
Free Energy of Ligand Removal in the Metal-Organic Framework UiO-66
Jessica Bristow, Katrine Svane, Davide Tiana, Jonathan Skelton, Julian D. Gale, Aron Walsh
May 05, 2016
We report an investigation of the `missing-linker phenomenon' in the Zr-based metal-organic framework UiO-66 using atomistic forcefield and quantum chemical methods. For a vacant benzene dicarboxylate ligand, the lowest energy...
Physical Activity and Abdominal Fat Distribution in Greenland.
Inger Katrine Dahl-Petersen, Søren Brage, Peter Bjerregaard, Janne Schurmann Tolstrup, Marit Eika Jørgensen
Nov 23, 2017
PURPOSE: We examined how total volume of physical activity and reallocation of time spent at various objectively measured intensities of physical activity (PA) were associated with overall and abdominal fat distribution in adult...
Voluntary policies on checkout foods and healthfulness of foods displayed at, or near, supermarket checkout areas
OBJECTIVE: To determine if voluntary policies on supermarket checkout foods are associated with a difference in the healthfulness of foods displayed at, or near, supermarket checkout areas. DESIGN: Cross-sectional survey of...
Socio-economic and age variations in response to supermarket-led checkout food policies
Katrine Ejlerskov, Stephen J Sharp, Martine Stead, Ashley J Adamson, Martin White, Jean Adams
Dec 21, 2018
The Influence of Maternal Obesity and Breastfeeding on Infant Appetite- and Growth-Related Hormone Concentrations
Anni Larnkjær, Ken K Ong, Emma M Carlsen, Katrine T Ejlerskov, Christian Mølgaard, Kim F Michaelsen
Oct 03, 2018
BACKGROUND/AIMS: Exposure to obesity during pregnancy may lead to adverse changes in the offspring's metabolic profile. We compared appetite- and growth-related hormones in a cohort of infants born to obese mothers (SKOT-II)...
Supermarket policies on less-healthy food at checkouts
Katrine T Ejlerskov, Stephen J Sharp, Martine Stead, Ashley J Adamson, Martin White, Jean Adams
Dec 21, 2018
BACKGROUND: In response to public concerns and campaigns, some United Kingdom supermarkets have implemented policies to reduce less-healthy food at checkouts. We explored the effects of these policies on purchases of...
Parasitic infections and resource economy of Danish Iron Age settlement through ancient DNA sequencing.
Katrine Wegener Tams, Martin Jensen Søe, Inga Merkyte, Frederik Valeur Seersholm, Peter Steen Henriksen, Susanne Klingenberg, Eske Willerslev, Kurt H Kjær, Anders Johannes Hansen, Christian Moliin Outzen Kapel
Sep 11, 2018
In this study, we screen archaeological soil samples by microscopy and analyse the samples by next generation sequencing to obtain results with parasites at species level and untargeted findings of plant and animal DNA. Three...
Age-associated Impairment of the Mucus Barrier Function is Associated with Profound Changes in Microbiota and Immunity.
Bruno Sovran, Floor Hugenholtz, Marlies Elderman, Adriaan A Van Beek, Katrine Graversen, Myrte Huijskes, Mark V Boekschoten, Huub FJ Savelkoul, Paul De Vos, Jan Dekker, Jerry M Wells
Jul 16, 2019
Aging significantly increases the vulnerability to gastrointestinal (GI) disorders but there are few studies investigating the key factors in aging that affect the GI tract. To address this knowledge gap, we used 10-week- and...
An integrated analysis of Maglemose bone points reframes the Early Mesolithic of Southern Scandinavia
Theis Zetner Trolle Jensen, Arne Sjöström, Anders Fischer, Erika Rosengren, Liam Thomas Lanigan, Ole Bennike, Kristine Korzow Richter, Kurt Joseph Gron, Meaghan Mackie, Morten Fischer Mortensen, Lasse Sørensen, David Chivall, Katrine Højholt Iversen, Alberto John Taurozzi, Jesper Olsen, Hannes Schroeder, Nicky Milner, Mikkel Sørensen, Matthew James Collins
Oct 14, 2020
Abstract: The extensive peat bogs of Southern Scandinavia have yielded rich Mesolithic archaeological assemblages, with one of the most iconic artefacts being the bone point. Although great in number they remain understudied....
An integrated analysis of Maglemose bone points reframes the Early Mesolithic of Southern Scandinavia.
Theis Zetner Trolle Jensen, Arne Sjöström, Anders Fischer, Erika Rosengren, Liam Thomas Lanigan, Ole Bennike, Kristine Korzow Richter, Kurt Joseph Gron, Meaghan Mackie, Morten Fischer Mortensen, Lasse Sørensen, David Chivall, Katrine Højholt Iversen, Alberto John Taurozzi, Jesper Olsen, Hannes Schroeder, Nicky Milner, Mikkel Sørensen, Matthew James Collins
Sep 29, 2020
An integrated analysis of Maglemose bone points reframes the Early Mesolithic of Southern Scandinavia
Theis Zetner Trolle Jensen, Arne Sjöström, Anders Fischer, Erika Rosengren, Liam Thomas Lanigan, Ole Bennike, Kristine Korzow Richter, Kurt Joseph Gron, Meaghan Mackie, Morten Fischer Mortensen, Lasse Sørensen, David Chivall, Katrine Højholt Iversen, Alberto John Taurozzi, Jesper Olsen, Hannes Schroeder, Nicky Milner, Mikkel Sørensen, Matthew James Collins
Oct 18, 2021
Abstract: The extensive peat bogs of Southern Scandinavia have yielded rich Mesolithic archaeological assemblages, with one of the most iconic artefacts being the bone point. Although great in number they remain understudied....
A 5700 year-old human genome and oral microbiome from chewed birch pitch.
Theis ZT Jensen, Jonas Niemann, Katrine Højholt Iversen, Anna K Fotakis, Shyam Gopalakrishnan, Åshild J Vågene, Mikkel Winther Pedersen, Mikkel-Holger S Sinding, Martin R Ellegaard, Morten E Allentoft, Liam T Lanigan, Alberto J Taurozzi, Sofie Holtsmark Nielsen, Michael W Dee, Martin N Mortensen, Mads C Christensen, Søren A Sørensen, Matthew J Collins, M Thomas P Gilbert, Martin Sikora, Simon Rasmussen, Hannes Schroeder
Feb 13, 2020
The rise of ancient genomics has revolutionised our understanding of human prehistory but this work depends on the availability of suitable samples. Here we present a complete ancient human genome and oral microbiome sequenced...
A 5700 year-old human genome and oral microbiome from chewed birch pitch
Theis Z. T. Jensen, Jonas Niemann, Katrine Højholt Iversen, Anna K. Fotakis, Shyam Gopalakrishnan, Åshild J. Vågene, Mikkel Winther Pedersen, Mikkel-Holger S. Sinding, Martin R. Ellegaard, Morten E. Allentoft, Liam T. Lanigan, Alberto J. Taurozzi, Sofie Holtsmark Nielsen, Michael W. Dee, Martin N. Mortensen, Mads C. Christensen, Søren A. Sørensen, Matthew J. Collins, M. Thomas P. Gilbert, Martin Sikora, Simon Rasmussen, Hannes Schroeder
Dec 22, 2020
Abstract: The rise of ancient genomics has revolutionised our understanding of human prehistory but this work depends on the availability of suitable samples. Here we present a complete ancient human genome and oral microbiome...
The first horse herders and the impact of early Bronze Age steppe expansions into Asia.
Peter de Barros Damgaard, Rui Martiniano, Jack Kamm, J Víctor Moreno-Mayar, Guus Kroonen, Michaël Peyrot, Gojko Barjamovic, Simon Rasmussen, Claus Zacho, Nurbol Baimukhanov, Victor Zaibert, Victor Merz, Arjun Biddanda, Ilja Merz, Valeriy Loman, Valeriy Evdokimov, Emma Usmanova, Brian Hemphill, Andaine Seguin-Orlando, Fulya Eylem Yediay, Inam Ullah, Karl-Göran Sjögren, Katrine Højholt Iversen, Jeremy Choin, Constanza de la Fuente, Melissa Ilardo, Hannes Schroeder, Vyacheslav Moiseyev, Andrey Gromov, Andrei Polyakov, Sachihiro Omura, Süleyman Yücel Senyurt, Habib Ahmad, Catriona McKenzie, Ashot Margaryan, Abdul Hameed, Abdul Samad, Nazish Gul, Muhammad Hassan Khokhar, OI Goriunova, Vladimir I Bazaliiskii, John Novembre, Andrzej W Weber, Ludovic Orlando, Morten E Allentoft, Rasmus Nielsen, Kristian Kristiansen, Martin Sikora, Alan K Outram, Richard Durbin, Eske Willerslev
Oct 30, 2020
The Yamnaya expansions from the western steppe into Europe and Asia during the Early Bronze Age (~3000 BCE) are believed to have brought with them Indo-European languages and possibly horse husbandry. We analyzed 74 ancient...
Hepatobiliary phenotypes of adults with alpha-1 antitrypsin deficiency.
Malin Fromme, Carolin V Schneider, Vitor Pereira, Karim Hamesch, Monica Pons, Matthias C Reichert, Federica Benini, Paul Ellis, Katrine H Thorhauge, Mattias Mandorfer, Barbara Burbaum, Vivien Woditsch, Joanna Chorostowska-Wynimko, Jef Verbeek, Frederik Nevens, Joan Genesca, Marc Miravitlles, Alexa Nuñez, Benedikt Schaefer, Heinz Zoller, Sabina Janciauskiene, Nélia Abreu, Luís Jasmins, Rui Gaspar, Rodrigo Liberal, Guilherme Macedo, Ravi Mahadeva, Catarina Gomes, Kai Markus Schneider, Michael Trauner, Aleksander Krag, Bibek Gooptu, Douglas Thorburn, Aileen Marshall, John R Hurst, David A Lomas, Frank Lammert, Nadine T Gaisa, Virginia Clark, William Griffiths, Christian Trautwein, Alice M Turner, Noel G McElvaney, Pavel Strnad
Mar 02, 2021
OBJECTIVE: Alpha-1 antitrypsin deficiency (AATD) is a common, potentially lethal inborn disorder caused by mutations in alpha-1 antitrypsin (AAT). Homozygosity for the 'Pi*Z' variant of AAT (Pi*ZZ genotype) causes lung and liver...
Population genomics of the Viking world.
Ashot Margaryan, Daniel J Lawson, Martin Sikora, Fernando Racimo, Simon Rasmussen, Ida Moltke, Lara M Cassidy, Emil Jørsboe, Andrés Ingason, Mikkel W Pedersen, Thorfinn Korneliussen, Helene Wilhelmson, Magdalena M Buś, Peter de Barros Damgaard, Rui Martiniano, Gabriel Renaud, Claude Bhérer, J Víctor Moreno-Mayar, Anna K Fotakis, Marie Allen, Raili Allmäe, Martyna Molak, Enrico Cappellini, Gabriele Scorrano, Hugh McColl, Alexandra Buzhilova, Allison Fox, Anders Albrechtsen, Berit Schütz, Birgitte Skar, Caroline Arcini, Ceri Falys, Charlotte Hedenstierna Jonson, Dariusz Błaszczyk, Denis Pezhemsky, Gordon Turner-Walker, Hildur Gestsdóttir, Inge Lundstrøm, Ingrid Gustin, Ingrid Mainland, Inna Potekhina, Italo M Muntoni, Jade Cheng, Jesper Stenderup, Jilong Ma, Julie Gibson, Jüri Peets, Jörgen Gustafsson, Katrine H Iversen, Linzi Simpson, Lisa Strand, Louise Loe, Maeve Sikora, Marek Florek, Maria Vretemark, Mark Redknap, Monika Bajka, Tamara Pushkina, Morten Søvsø, Natalia Grigoreva, Tom Christensen, Ole Kastholm, Otto Uldum, Pasquale Favia, Per Holck, Sabine Sten, Símun V Arge, Sturla Ellingvåg, Vayacheslav Moiseyev, Wiesław Bogdanowicz, Yvonne Magnusson, Ludovic Orlando, Peter Pentz, Mads Dengsø Jessen, Anne Pedersen, Mark Collard, Daniel G Bradley, Marie Louise Jørkov, Jette Arneborg, Niels Lynnerup, Neil Price, M Thomas P Gilbert, Morten E Allentoft, Jan Bill, Søren M Sindbæk, Lotte Hedeager, Kristian Kristiansen, Rasmus Nielsen, Thomas Werge, Eske Willerslev
Nov 05, 2020
The maritime expansion of Scandinavian populations during the Viking Age (about AD 750-1050) was a far-flung transformation in world history1,2. Here we sequenced the genomes of 442 humans from archaeological sites across Europe...
Discovery of rare variants associated with blood pressure regulation through meta-analysis of 1.3 million individuals.
Praveen Surendran, Elena V Feofanova, Najim Lahrouchi, Ioanna Ntalla, Savita Karthikeyan, James Cook, Lingyan Chen, Borbala Mifsud, Chen Yao, Aldi T Kraja, James H Cartwright, Jacklyn N Hellwege, Ayush Giri, Vinicius Tragante, Gudmar Thorleifsson, Dajiang J Liu, Bram P Prins, Isobel D Stewart, Claudia P Cabrera, James M Eales, Artur Akbarov, Paul L Auer, Lawrence F Bielak, Joshua C Bis, Vickie S Braithwaite, Jennifer A Brody, E Warwick Daw, Helen R Warren, Fotios Drenos, Sune Fallgaard Nielsen, Jessica D Faul, Eric B Fauman, Cristiano Fava, Teresa Ferreira, Christopher N Foley, Nora Franceschini, He Gao, Olga Giannakopoulou, Franco Giulianini, Daniel F Gudbjartsson, Xiuqing Guo, Sarah E Harris, Aki S Havulinna, Anna Helgadottir, Jennifer E Huffman, Shih-Jen Hwang, Stavroula Kanoni, Jukka Kontto, Martin G Larson, Ruifang Li-Gao, Jaana Lindström, Luca A Lotta, Yingchang Lu, Jian'an Luan, Anubha Mahajan, Giovanni Malerba, Nicholas GD Masca, Hao Mei, Cristina Menni, Dennis O Mook-Kanamori, David Mosen-Ansorena, Martina Müller-Nurasyid, Guillaume Paré, Dirk S Paul, Markus Perola, Alaitz Poveda, Rainer Rauramaa, Melissa Richard, Tom G Richardson, Nuno Sepúlveda, Xueling Sim, Albert V Smith, Jennifer A Smith, James R Staley, Alena Stanáková, Patrick Sulem, Sébastien Thériault, Unnur Thorsteinsdottir, Stella Trompet, Tibor V Varga, Digna R Velez Edwards, Giovanni Veronesi, Stefan Weiss, Sara M Willems, Jie Yao, Robin Young, Bing Yu, Weihua Zhang, Jing-Hua Zhao, Wei Zhao, Wei Zhao, Evangelos Evangelou, Stefanie Aeschbacher, Eralda Asllanaj, Stefan Blankenberg, Lori L Bonnycastle, Jette Bork-Jensen, Ivan Brandslund, Peter S Braund, Stephen Burgess, Kelly Cho, Cramer Christensen, John Connell, Renée de Mutsert, Anna F Dominiczak, Marcus Dörr, Gudny Eiriksdottir, Aliki-Eleni Farmaki, J Michael Gaziano, Niels Grarup, Megan L Grove, Göran Hallmans, Torben Hansen, Christian T Have, Gerardo Heiss, Marit E Jørgensen, Pekka Jousilahti, Eero Kajantie, Mihir Kamat, AnneMari Käräjämäki, Fredrik Karpe, Heikki A Koistinen, Csaba P Kovesdy, Kari Kuulasmaa, Tiina Laatikainen, Lars Lannfelt, I-Te Lee, Wen-Jane Lee, Lifelines Cohort Study, Allan Linneberg, Lisa W Martin, Marie Moitry, Girish Nadkarni, Matt J Neville, Colin NA Palmer, George J Papanicolaou, Oluf Pedersen, James Peters, Neil Poulter, Asif Rasheed, Katrine L Rasmussen, N William Rayner, Reedik Mägi, Frida Renström, Rainer Rettig, Jacques Rossouw, Pamela J Schreiner, Peter S Sever, Emil L Sigurdsson, Tea Skaaby, Yan V Sun, Johan Sundstrom, Gudmundur Thorgeirsson, Tõnu Esko, Elisabetta Trabetti, Philip S Tsao, Tiinamaija Tuomi, Stephen T Turner, Ioanna Tzoulaki, Ilonca Vaartjes, Anne-Claire Vergnaud, Cristen J Willer, Peter WF Wilson, Daniel R Witte, Ekaterina Yonova-Doing, He Zhang, Naheed Aliya, Peter Almgren, Philippe Amouyel, Folkert W Asselbergs, Michael R Barnes, Alexandra I Blakemore, Michael Boehnke, Michiel L Bots, Erwin P Bottinger, Julie E Buring, John C Chambers, Yii-Der Ida Chen, Rajiv Chowdhury, David Conen, Adolfo Correa, George Davey Smith, Rudolf A de Boer, Ian J Deary, George Dedoussis, Panos Deloukas, Emanuele Di Angelantonio, Paul Elliott, EPIC-CVD, EPIC-InterAct, Stephan B Felix, Jean Ferrières, Ian Ford, Myriam Fornage, Paul W Franks, Stephen Franks, Philippe Frossard, Giovanni Gambaro, Tom R Gaunt, Leif Groop, Vilmundur Gudnason, Tamara B Harris, Caroline Hayward, Branwen J Hennig, Karl-Heinz Herzig, Erik Ingelsson, Jaakko Tuomilehto, Marjo-Riitta Järvelin, J Wouter Jukema, Sharon LR Kardia, Frank Kee, Jaspal S Kooner, Charles Kooperberg, Lenore J Launer, Lars Lind, Ruth JF Loos, Abdulla Al Shafi Majumder, Markku Laakso, Mark I McCarthy, Olle Melander, Karen L Mohlke, Alison D Murray, Børge Grønne Nordestgaard, Marju Orho-Melander, Chris J Packard, Sandosh Padmanabhan, Walter Palmas, Ozren Polasek, David J Porteous, Andrew M Prentice, Michael A Province, Caroline L Relton, Kenneth Rice, Paul M Ridker, Olov Rolandsson, Frits R Rosendaal, Jerome I Rotter, Igor Rudan, Veikko Salomaa, Nilesh J Samani, Naveed Sattar, Wayne H-H Sheu, Blair H Smith, Nicole Soranzo, Timothy D Spector, John M Starr, Sylvain Sebert, Kent D Taylor, Timo A Lakka, Nicholas J Timpson, Martin D Tobin, Understanding Society Scientific Group, Pim van der Harst, Peter van der Meer, Vasan S Ramachandran, Niek Verweij, Jarmo Virtamo, Uwe Völker, David R Weir, Eleftheria Zeggini, Fadi J Charchar, Million Veteran Program, Nicholas J Wareham, Claudia Langenberg, Maciej Tomaszewski, Adam S Butterworth, Mark J Caulfield, John Danesh, Todd L Edwards, Hilma Holm, Adriana M Hung, Cecilia M Lindgren, Chunyu Liu, Alisa K Manning, Andrew P Morris, Alanna C Morrison, Christopher J O'Donnell, Bruce M Psaty, Danish Saleheen, Kari Stefansson, Eric Boerwinkle, Daniel I Chasman, Daniel Levy, Christopher Newton-Cheh, Patricia B Munroe, Joanna MM Howson
Nov 04, 2020
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