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The Nested Kingman Coalescent
The nested Kingman coalescent describes the ancestral tree of a population undergoing neutral evolution at the level of individuals and at the level of species, simultaneously. We study the speed at which the number of...
The Nested Kingman Coalescent
The nested Kingman coalescent describes the ancestral tree of a population undergoing neutral evolution at the level of individuals and at the level of species, simultaneously. We study the speed at which the number of...
Emergence of condensation in Kingman's model of selection and mutation
We describe the onset of condensation in the simple model for the balance between selection and mutation given by Kingman in terms of a scaling limit theorem. Loosely speaking, this shows that the wave moving towards genes of...
Emergence of condensation in Kingman's model of selection and mutation
We describe the onset of condensation in the simple model for the balance between selection and mutation given by Kingman in terms of a scaling limit theorem. Loosely speaking, this shows that the wave moving towards genes of...
Budding-like division of all-aqueous emulsion droplets modulated by networks of protein nanofibrils.
Yang Song, Thomas CT Michaels, Qingming Ma, Zhou Liu, Hao Yuan, Shuichi Takayama, Tuomas PJ Knowles, Ho Cheung Shum
Sep 29, 2018
Networks of natural protein nanofibrils, such as cytoskeletal filaments, control the shape and the division of cells, yet mimicking this functionality in a synthetic setting has proved challenging. Here, we demonstrate that...
Hippocampal lesions facilitate instrumental learning with delayed reinforcement but induce impulsive choice in rats.
BACKGROUND: Animals must frequently act to influence the world even when the reinforcing outcomes of their actions are delayed. Learning with action-outcome delays is a complex problem, and little is known of the neural...
Sibe
BACKGROUND: Evolutionary information contained in the amino acid sequences of proteins specifies the biological function and fold, but exactly what information contained in the protein sequence drives both of these processes?...
The benefits of explicit teaching of language for curriculum learning in the Physical Education classroom
Among the many subjects taught at primary, secondary and tertiary institutions physical education (PE) has had limited discussion with respect to the language of PE. As an examination subject in secondary school, physical...
The benefits of explicit teaching of language for curriculum learning in the Physical Education classroom
Among the many subjects taught at primary, secondary and tertiary institutions physical education (PE) has had limited discussion with respect to the language of PE. As an examination subject in secondary school, physical...
Banking System Incidents Analysis Using Knowledge Graph
Risk incidents in the banks' systems have caused significant social impacts and economic losses. This study proposes a risk incident knowledge modeling and analysis approach based on the knowledge graphs to realize the effective...
Published by: IGI Global Scientific Publishing
Civic Crowdfunding for Social Work Research
Civic crowdfunding for research purposes has been an emerging trend in scientific fields over the past few years. This article presents findings from a mixed methods analysis of 152 social science research projects that...
Myocardin overexpression is sufficient for promoting the development of a mature smooth muscle cell-like phenotype from human embryonic stem cells.
BACKGROUND: Myocardin is thought to have a key role in smooth muscle cell (SMC) development by acting on CArG-dependent genes. However, it is unclear whether myocardin-induced SMC maturation and increases in agonist-induced...
Generation of human vascular smooth muscle subtypes provides insight into embryological origin-dependent disease susceptibility.
Christine Cheung, Andreia S Bernardo, Matthew WB Trotter, Roger A Pedersen, Sanjay Sinha
Jan 23, 2018
Heterogeneity of embryological origins is a hallmark of vascular smooth muscle cells (SMCs) and may influence the development of vascular disease. Differentiation of human pluripotent stem cells (hPSCs) into developmental...
Civic Crowdfunding for Social Work Research
Civic crowdfunding for research purposes has been an emerging trend in scientific fields over the past few years. This article presents findings from a mixed methods analysis of 152 social science research projects that...
Fractures in the education-economy relationship
This paper undertakes a critical theoretical and empirical analysis of the traditional approach to analysing the education-economy relationship: skill bias technological change theory. It argues that while leading skill bias...
Fractures in the education-economy relationship
This paper undertakes a critical theoretical and empirical analysis of the traditional approach to analysing the education-economy relationship: skill bias technological change theory. It argues that while leading skill bias...
Systematic bias in high-throughput sequencing data and its correction by BEADS.
Genomic sequences obtained through high-throughput sequencing are not uniformly distributed across the genome. For example, sequencing data of total genomic DNA show significant, yet unexpected enrichments on promoters and...
Syntactic computations in the language network
The core human capacity of syntactic analysis involves a left hemisphere network involving left inferior frontal gyrus (LIFG) and posterior middle temporal gyrus (LMTG) and the anatomical connections between them. Here we use...
Can achievement at medical admission tests predict future performance in postgraduate clinical assessments? A UK-based national cohort study.
OBJECTIVE: To determine whether scores on two undergraduate admissions tests (BioMedical Admissions Test (BMAT) and University Clinical Aptitude Test (UCAT)) predict performance on the postgraduate Membership of the Royal...
Modelling semi-attributable toxicity in dual-agent phase I trials with non-concurrent drug administration.
Bayesian methods adaptive designs dose-toxicity modelling Drug Combinations phase I trials Algorithms Antineoplastic Agents Antineoplastic Combined Chemotherapy Protocols Biostatistics Clinical Trials Phase I as Topic Cohort Studies Computer Simulation Dose-Response Relationship Drug Drug Administration Schedule Humans Interatrial Block Models Statistical Neoplasms
Longitudinal touchscreen use across early development is associated with faster exogenous and reduced endogenous attention control
Childhood screen time is associated with both attentional difficulties (for television viewing) and benefits (in action video gamers), but few studies have investigated today’s pervasive touchscreen devices (e.g. smartphones and...
Longitudinal touchscreen use across early development is associated with faster exogenous and reduced endogenous attention control
Childhood screen time is associated with both attentional difficulties (for television viewing) and benefits (in action video gamers), but few studies have investigated today’s pervasive touchscreen devices (e.g. smartphones and...
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