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Improving the health of adolescents
While in the Nordic countries we have well-developed welfare policies and several structural, statutory measures in place aiming to promote public health, studies from these countries are often absent from systematic reviews of...
Phenotyping Genetic Diseases Using an Extension of ?-Scores for Multivariate Data
As the field of genomics matures, more complex genotypes and phenotypes are being studied. Fanconi anemia (FA), for example, is an inherited chromosome instability syndrome with a complex array of variable disease phenotypes...
Published by: http://hdl.handle.net/10209/490
U-Scores for Multivariate Data In Sports
In many sport competitions athletes, teams, or countries are evaluated based on several variables. The strong assumptions underlying traditional 'linear weight' scoring systems (that the relative importance, interactions and...
statistics performance Ability triathalon baseball Olympics Soccer Tour-de-France multivariate Ranking Voting Medicine and Health Sciences
Published by: Rockefeller University
Improving the health of adolescents
While in the Nordic countries we have well-developed welfare policies and several structural, statutory measures in place aiming to promote public health, studies from these countries are often absent from systematic reviews of...
Biofilm streamers cause catastrophic disruption of flow with consequences for environmental and medical systems.
Biofilms are antibiotic-resistant, sessile bacterial communities that occupy most moist surfaces on Earth and cause chronic and medical device-associated infections. Despite their importance, basic information about biofilm...
Primary prevention of overweight and obesity in adolescents
Summary The aim of this overview of systematic reviews was to summarize evidence from up-to-date reviews of the effectiveness of interventions aimed at preventing overweight and obesity in adolescents aged 10 to 19 years. We...
Promoting Physical Activity Policy
Kate Oldridge-Turner, Margarita Kokkorou, Fiona Sing, Knut-Inge Klepp, Harry Rutter, Arnfinn Helleve, Bryony Sinclair, Louise Meincke, Giota Mitrou, Martin Wiseman, Kate Allen
Apr 30, 2022
From Single-SNP to Wide-Locus: Genome-Wide Association Studies Identifying Functionally Related Genes and Intragenic Regions in Small Sample Studies
Knut M Wittkowski, Vikas Sonakya, Tingting Song, Martin P Seybold, Mehdi Keddache, Martina Durner
Jan 01, 0001
Background: Genome Wide Association Studies (GWAS) have had limited success when applied to complex diseases. Analyzing SNPs individually requires several large studies to integrate the often divergent results. In the presence...
common disease Epilepsy Epistasis Genome-Wide Association Study GWAS Phase III trials ras-pathway u-statistics Life Sciences
Published by: Future Medicine
Promoting Physical Activity Policy
Kate Oldridge-Turner, Margarita Kokkorou, Fiona Sing, Knut-Inge Klepp, Harry Rutter, Arnfinn Helleve, Bryony Sinclair, Louise Meincke, Giota Mitrou, Martin Wiseman, Kate Allen
Apr 30, 2022
Primary prevention of overweight and obesity in adolescents
Summary The aim of this overview of systematic reviews was to summarize evidence from up-to-date reviews of the effectiveness of interventions aimed at preventing overweight and obesity in adolescents aged 10 to 19 years. We...
Changes in diet through adolescence and early adulthood
Eleanor M Winpenny, Esther Mf van Sluijs, Martin White, Knut-Inge Klepp, Bente Wold, Nanna Lien
Nov 19, 2018
BACKGROUND: Early adulthood is a period associated with poor diet and rapid weight gain. This is also an age of transition, including environmental, social and lifestyle changes which may be associated with changes in diet. We...
Copynumber
Gro Nilsen, Knut Liestøl, Peter Van Loo, Hans Kristian Moen Vollan, Marianne B Eide, Oscar M Rueda, Suet-Feung Chin, Roslin Russell, Lars O Baumbusch, Carlos Caldas, Anne-Lise Børresen-Dale, Ole Christian Lingjaerde
Feb 26, 2013
DNA copy number motifs are strong and independent predictors of survival in breast cancer.
Arne V Pladsen, Gro Nilsen, Oscar M Rueda, Miriam R Aure, Ørnulf Borgan, Knut Liestøl, Valeria Vitelli, Arnoldo Frigessi, Anita Langerød, Anthony Mathelier, OSBREAC, Olav Engebråten, Vessela Kristensen, David C Wedge, Peter Van Loo, Carlos Caldas, Anne-Lise Børresen-Dale, Hege G Russnes, Ole Christian Lingjaerde
May 29, 2020
Somatic copy number alterations are a frequent sign of genome instability in cancer. A precise characterization of the genome architecture would reveal underlying instability mechanisms and provide an instrument for outcome...
Disturbed neuronal ER-Golgi sorting of unassembled glycine receptors suggests altered subcellular processing is a cause of human hyperekplexia.
Natascha Schaefer, Christoph J Kluck, Kerry L Price, Heike Meiselbach, Nadine Vornberger, Stephan Schwarzinger, Stephanie Hartmann, Georg Langlhofer, Solveig Schulz, Nadja Schlegel, Knut Brockmann, Bryan Lynch, Cord-Michael Becker, Sarah CR Lummis, Carmen Villmann
Sep 02, 2015
assembly biogenesis glycine receptor human hyperekplexia rescue of function subcompartimentalization Amino Acid Sequence Animals COS Cells Child Chlorocebus aethiops Endoplasmic Reticulum Female Golgi Apparatus HEK293 Cells Humans Infant Intracellular Space Male Mice Molecular Sequence Data Neurons Pedigree Protein Structure Secondary Protein Structure Tertiary Receptors Glycine Stiff-Person Syndrome
Proteinase-3 and myeloperoxidase serotype in relation to demographic factors and geographic distribution in anti-neutrophil cytoplasmic antibody-associated glomerulonephritis.
Maria Weiner, Rune Bjørneklett, Zdenka Hrušková, Bruce Mackinnon, Caroline J Poulton, Leo Sindelar, Aladdin J Mohammad, Per Eriksson, Loreto Gesualdo, Duvuru Geetha, Matija Crnogorac, David Jayne, Susan L Hogan, Colin Geddes, Vladimir Tesar, Knut Aasarød, Mårten Segelmark
May 13, 2019
BACKGROUND: In anti-neutrophil cytoplasmic antibody (ANCA)-associated glomerulonephritis, antigen specificity varies between myeloperoxidase (MPO) and proteinase 3 (PR3). This has been reported to vary in relation to age...
Aged Anti-Neutrophil Cytoplasmic Antibody-Associated Vasculitis Antibodies Antineutrophil Cytoplasmic Antibody Specificity Biopsy Czech Republic Demography Female Geography glomerulonephritis Humans Italy Male Middle Aged Myeloblastin Norway Peroxidase Registries Serogroup Sweden United Kingdom United States
Catalogue of the Diptera (Insecta) of Morocco- an annotated checklist, with distributions and a bibliography.
Kawtar Kettani, Martin J Ebejer, David M Ackland, Gerhard Bächli, David Barraclough, Miroslav Barták, Miguel Carles-Tolrá, Milos Černý, Pierfilippo Cerretti, Peter Chandler, Mohamed Dakki, Christophe Daugeron, Herman De Jong, Josef Dils, Henry Disney, Boris Droz, Neal Evenhuis, Paul Gatt, Gustavo Graciolli, Igor Y Grichanov, Jean-Paul Haenni, Martin Hauser, Oumnia Himmi, Iain MacGowan, Bruno Mathieu, Mohamed Mouna, Lorenzo Munari, Emilia P Nartshuk, Oleg P Negrobov, Pjotr Oosterbroek, Thomas Pape, Adrian C Pont, Grigory V Popov, Knut Rognes, Marcela Skuhravá, Vaclav Skuhravý, Martin Speight, Guy Tomasovic, Bouchra Trari, Hans-Peter Tschorsnig, Jean-Claude Vala, Michael von Tschirnhaus, Rüdiger Wagner, Daniel Whitmore, Andrzej J Woźnica, Tadeusz Zatwarnicki, Peter Zwick
Aug 14, 2022
The faunistic knowledge of the Diptera of Morocco recorded from 1787 to 2021 is summarized and updated in this first catalogue of Moroccan Diptera species. A total of 3057 species, classified into 948 genera and 93 families (21...
DNA glycosylase Neil3 regulates vascular smooth muscle cell biology during atherosclerosis development.
Ana Quiles-Jiménez, Ida Gregersen, Filip M Segers, Tonje Skarpengland, Penelope Kroustallaki, Kuan Yang, Xiang Yi Kong, Knut H Lauritzen, Maria B Olsen, Tom Rune Karlsen, Tuula A Nyman, Ellen L Sagen, Vigdis Bjerkeli, Rajikala Suganthan, Ståle Nygård, Katja Scheffler, Jurriën Prins, Eric Van der Veer, Jonas Ds Øgaard, Yngvar Fløisand, Helle F Jørgensen, Kirsten B Holven, Erik A Biessen, Hilde Nilsen, Tuva B Dahl, Sverre Holm, Martin R Bennett, Pål Aukrust, Magnar Bjørås, Bente Halvorsen
Mar 17, 2021
BACKGROUND AND AIMS: Atherogenesis involves a complex interaction between immune cells and lipids, processes greatly influenced by the vascular smooth muscle cell (VSMC) phenotype. The DNA glycosylase NEIL3 has previously been...
Akt signaling Atherosclerosis DNA damage repair NEIL3 Phenotypic transdifferentiation Vascular smooth muscle cells Animals Atherosclerosis Cell Proliferation Cells Cultured DNA Glycosylases Endodeoxyribonucleases Humans Mice Mice Inbred C57BL Mice Knockout ApoE Muscle Smooth Vascular Myocytes Smooth Muscle N-Glycosyl Hydrolases Phenotype Plaque Atherosclerotic
Variations in accelerometry measured physical activity and sedentary time across Europe - harmonized analyses of 47,497 children and adolescents.
Jostein Steene-Johannessen, Bjørge Herman Hansen, Knut Eirik Dalene, Elin Kolle, Kate Northstone, Niels Christian Møller, Anders Grøntved, Niels Wedderkopp, Susi Kriemler, Angie S Page, Jardena J Puder, John J Reilly, Luis B Sardinha, Esther M F van Sluijs, Lars Bo Andersen, Hidde van der Ploeg, Wolfgang Ahrens, Claudia Flexeder, Marie Standl, Holger Shculz, Luis A Moreno, Stefaan De Henauw, Nathalie Michels, Greet Cardon, Francisco B Ortega, Jonatan Ruiz, Susana Aznar, Mikael Fogelholm, Andrew Decelis, Line Grønholt Olesen, Mads Fiil Hjorth, Rute Santos, Susana Vale, Lars Breum Christiansen, Russ Jago, Laura Basterfield, Christopher G Owen, Claire M Nightingale, Gabriele Eiben, Angela Polito, Fabio Lauria, Jeremy Vanhelst, Charalambos Hadjigeorgiou, Kenn Konstabel, Dénes Molnár, Ole Sprengeler, Yannis Manios, Jaanus Harro, Anthony Kafatos, Sigmund Alfred Anderssen, Ulf Ekelund
Apr 19, 2020
BACKGROUND:Levels of physical activity and variation in physical activity and sedentary time by place and person in European children and adolescents are largely unknown. The objective of the study was to assess the variations...
Variations in accelerometry measured physical activity and sedentary time across Europe - harmonized analyses of 47,497 children and adolescents.
Jostein Steene-Johannessen, Bjørge Herman Hansen, Knut Eirik Dalene, Elin Kolle, Kate Northstone, Niels Christian Møller, Anders Grøntved, Niels Wedderkopp, Susi Kriemler, Angie S Page, Jardena J Puder, John J Reilly, Luis B Sardinha, Esther Mf van Sluijs, Lars Bo Andersen, Hidde van der Ploeg, Wolfgang Ahrens, Claudia Flexeder, Marie Standl, Holger Shculz, Luis A Moreno, Stefaan De Henauw, Nathalie Michels, Greet Cardon, Francisco B Ortega, Jonatan Ruiz, Susana Aznar, Mikael Fogelholm, Andrew Decelis, Line Grønholt Olesen, Mads Fiil Hjorth, Rute Santos, Susana Vale, Lars Breum Christiansen, Russ Jago, Laura Basterfield, Christopher G Owen, Claire M Nightingale, Gabriele Eiben, Angela Polito, Fabio Lauria, Jeremy Vanhelst, Charalambos Hadjigeorgiou, Kenn Konstabel, Dénes Molnár, Ole Sprengeler, Yannis Manios, Jaanus Harro, Anthony Kafatos, Sigmund Alfred Anderssen, Ulf Ekelund, Determinants of Diet and Physical Activity knowledge hub (DEDIPAC)
Jan 14, 2021
BACKGROUND: Levels of physical activity and variation in physical activity and sedentary time by place and person in European children and adolescents are largely unknown. The objective of the study was to assess the variations...
Variations in accelerometry measured physical activity and sedentary time across Europe – harmonized analyses of 47,497 children and adolescents
Jostein Steene-Johannessen, Bjørge Herman Hansen, Knut Eirik Dalene, Elin Kolle, Kate Northstone, Niels Christian Møller, Anders Grøntved, Niels Wedderkopp, Susi Kriemler, Angie S. Page, Jardena J. Puder, John J. Reilly, Luis B. Sardinha, Esther M. F. van Sluijs, Lars Bo Andersen, Hidde van der Ploeg, Wolfgang Ahrens, Claudia Flexeder, Marie Standl, Holger Shculz, Luis A. Moreno, Stefaan De Henauw, Nathalie Michels, Greet Cardon, Francisco B. Ortega, Jonatan Ruiz, Susana Aznar, Mikael Fogelholm, Andrew Decelis, Line Grønholt Olesen, Mads Fiil Hjorth, Rute Santos, Susana Vale, Lars Breum Christiansen, Russ Jago, Laura Basterfield, Christopher G. Owen, Claire M. Nightingale, Gabriele Eiben, Angela Polito, Fabio Lauria, Jeremy Vanhelst, Charalambos Hadjigeorgiou, Kenn Konstabel, Dénes Molnár, Ole Sprengeler, Yannis Manios, Jaanus Harro, Anthony Kafatos, Sigmund Alfred Anderssen, Ulf Ekelund, L. B. Andersen, S. Anderssen, A. J. Atkin, G. Cardon, R. Davey, U. Ekelund, D. W. Esliger, P. Hallal, B. H. Hansen, K. F. Janz, S. Kriemler, N. Møller, K. Northstone, R. Pate, J. J. Puder, J. Reilly, J. Salmon, L. B. Sardinha, L. B. Sherar, E. M. F. van Sluijs
Jun 06, 2020
Variations in accelerometry measured physical activity and sedentary time across Europe – harmonized analyses of 47,497 children and adolescents
Jostein Steene-Johannessen, Bjørge Herman Hansen, Knut Eirik Dalene, Elin Kolle, Kate Northstone, Niels Christian Møller, Anders Grøntved, Niels Wedderkopp, Susi Kriemler, Angie S. Page, Jardena J. Puder, John J. Reilly, Luis B. Sardinha, Esther M. F. van Sluijs, Lars Bo Andersen, Hidde van der Ploeg, Wolfgang Ahrens, Claudia Flexeder, Marie Standl, Holger Shculz, Luis A. Moreno, Stefaan De Henauw, Nathalie Michels, Greet Cardon, Francisco B. Ortega, Jonatan Ruiz, Susana Aznar, Mikael Fogelholm, Andrew Decelis, Line Grønholt Olesen, Mads Fiil Hjorth, Rute Santos, Susana Vale, Lars Breum Christiansen, Russ Jago, Laura Basterfield, Christopher G. Owen, Claire M. Nightingale, Gabriele Eiben, Angela Polito, Fabio Lauria, Jeremy Vanhelst, Charalambos Hadjigeorgiou, Kenn Konstabel, Dénes Molnár, Ole Sprengeler, Yannis Manios, Jaanus Harro, Anthony Kafatos, Sigmund Alfred Anderssen, Ulf Ekelund, L. B. Andersen, S. Anderssen, A. J. Atkin, G. Cardon, R. Davey, U. Ekelund, D. W. Esliger, P. Hallal, B. H. Hansen, K. F. Janz, S. Kriemler, N. Møller, K. Northstone, R. Pate, J. J. Puder, J. Reilly, J. Salmon, L. B. Sardinha, L. B. Sherar, E. M. F. van Sluijs
Mar 18, 2021
Genome-wide analysis of 53,400 people with irritable bowel syndrome highlights shared genetic pathways with mood and anxiety disorders
Chris Eijsbouts, Tenghao Zheng, Nicholas A. Kennedy, Ferdinando Bonfiglio, Carl A. Anderson, Loukas Moutsianas, Joanne Holliday, Jingchunzi Shi, Suyash Shringarpure, Alexandru-Ioan Voda, Gianrico Farrugia, Andre Franke, Matthias Hübenthal, Gonçalo Abecasis, Matthew Zawistowski, Anne Heidi Skogholt, Eivind Ness-Jensen, Kristian Hveem, Tõnu Esko, Maris Teder-Laving, Alexandra Zhernakova, Michael Camilleri, Guy Boeckxstaens, Peter J. Whorwell, Robin Spiller, Gil McVean, Mauro D’Amato, Luke Jostins, Miles Parkes, Michelle Agee, Stella Aslibekyan, Adam Auton, Robert K. Bell, Katarzyna Bryc, Sarah K. Clark, Sarah L. Elson, Kipper Fletez-Brant, Pierre Fontanillas, Nicholas A. Furlotte, Pooja M. Gandhi, Karl Heilbron, Barry Hicks, David A. Hinds, Karen E. Huber, Ethan M. Jewett, Yunxuan Jiang, Aaron Kleinman, Keng-Han Lin, Nadia K. Litterman, Marie K. Luff, Jey C. McCreight, Matthew H. McIntyre, Kimberly F. McManus, Joanna L. Mountain, Sahar V. Mozaffari, Priyanka Nandakumar, Elizabeth S. Noblin, Carrie A. M. Northover, Jared O’Connell, Aaron A. Petrakovitz, Steven J. Pitts, G. David Poznik, J. Fah Sathirapongsasuti, Anjali J. Shastri, Janie F. Shelton, Chao Tian, Joyce Y. Tung, Robert J. Tunney, Vladimir Vacic, Xin Wang, Amir S. Zare, Purna Kashyap, Lin Chang, Emeran Mayer, Margaret Heitkemper, Gregory S. Sayuk, Tamar Ringel-Kulka, Yehuda Ringel, William D. Chey, Shanti Eswaran, Juanita L. Merchant, Robert J. Shulman, Luis Bujanda, Koldo Garcia-Etxebarria, Aldona Dlugosz, Greger Lindberg, Peter T. Schmidt, Pontus Karling, Bodil Ohlsson, Susanna Walter, Åshild O. Faresjö, Magnus Simren, Jonas Halfvarson, Piero Portincasa, Giovanni Barbara, Paolo Usai-Satta, Matteo Neri, Gerardo Nardone, Rosario Cuomo, Francesca Galeazzi, Massimo Bellini, Anna Latiano, Lesley Houghton, Daisy Jonkers, Alexander Kurilshikov, Rinse K. Weersma, Mihai Netea, Jonas Tesarz, Annika Gauss, Miriam Goebel-Stengel, Viola Andresen, Thomas Frieling, Christian Pehl, Rainer Schaefert, Beate Niesler, Wolfgang Lieb, Kurt Hanevik, Nina Langeland, Knut-Arne Wensaas, Sverre Litleskare, Maiken E. Gabrielsen, Laurent Thomas, Vincent Thijs, Robin Lemmens, Lukas Van Oudenhove, Mira Wouters
Nov 06, 2021
Genome-wide analysis of 53,400 people with irritable bowel syndrome highlights shared genetic pathways with mood and anxiety disorders
Chris Eijsbouts, Tenghao Zheng, Nicholas A. Kennedy, Ferdinando Bonfiglio, Carl A. Anderson, Loukas Moutsianas, Joanne Holliday, Jingchunzi Shi, Suyash Shringarpure, Alexandru-Ioan Voda, Gianrico Farrugia, Andre Franke, Matthias Hübenthal, Gonçalo Abecasis, Matthew Zawistowski, Anne Heidi Skogholt, Eivind Ness-Jensen, Kristian Hveem, Tõnu Esko, Maris Teder-Laving, Alexandra Zhernakova, Michael Camilleri, Guy Boeckxstaens, Peter J. Whorwell, Robin Spiller, Gil McVean, Mauro D’Amato, Luke Jostins, Miles Parkes, Michelle Agee, Stella Aslibekyan, Adam Auton, Robert K. Bell, Katarzyna Bryc, Sarah K. Clark, Sarah L. Elson, Kipper Fletez-Brant, Pierre Fontanillas, Nicholas A. Furlotte, Pooja M. Gandhi, Karl Heilbron, Barry Hicks, David A. Hinds, Karen E. Huber, Ethan M. Jewett, Yunxuan Jiang, Aaron Kleinman, Keng-Han Lin, Nadia K. Litterman, Marie K. Luff, Jey C. McCreight, Matthew H. McIntyre, Kimberly F. McManus, Joanna L. Mountain, Sahar V. Mozaffari, Priyanka Nandakumar, Elizabeth S. Noblin, Carrie A. M. Northover, Jared O’Connell, Aaron A. Petrakovitz, Steven J. Pitts, G. David Poznik, J. Fah Sathirapongsasuti, Anjali J. Shastri, Janie F. Shelton, Chao Tian, Joyce Y. Tung, Robert J. Tunney, Vladimir Vacic, Xin Wang, Amir S. Zare, Purna Kashyap, Lin Chang, Emeran Mayer, Margaret Heitkemper, Gregory S. Sayuk, Tamar Ringel-Kulka, Yehuda Ringel, William D. Chey, Shanti Eswaran, Juanita L. Merchant, Robert J. Shulman, Luis Bujanda, Koldo Garcia-Etxebarria, Aldona Dlugosz, Greger Lindberg, Peter T. Schmidt, Pontus Karling, Bodil Ohlsson, Susanna Walter, Åshild O. Faresjö, Magnus Simren, Jonas Halfvarson, Piero Portincasa, Giovanni Barbara, Paolo Usai-Satta, Matteo Neri, Gerardo Nardone, Rosario Cuomo, Francesca Galeazzi, Massimo Bellini, Anna Latiano, Lesley Houghton, Daisy Jonkers, Alexander Kurilshikov, Rinse K. Weersma, Mihai Netea, Jonas Tesarz, Annika Gauss, Miriam Goebel-Stengel, Viola Andresen, Thomas Frieling, Christian Pehl, Rainer Schaefert, Beate Niesler, Wolfgang Lieb, Kurt Hanevik, Nina Langeland, Knut-Arne Wensaas, Sverre Litleskare, Maiken E. Gabrielsen, Laurent Thomas, Vincent Thijs, Robin Lemmens, Lukas Van Oudenhove, Mira Wouters
Nov 22, 2021
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