De novo SIX2 activation in human kidneys treated with neonatal kidney stem/progenitor cells.
Fanny Oliveira Arcolino,
Sarah Hosgood,
Sara Akalay,
Nina Jordan,
Jean Herman,
Tegwen Elliott,
Koenraad Veys,
Kurt Vermeire,
Ben Sprangers,
Michael Nicholson,
Lambertus van den Heuvel,
Elena Levtchenko
Aug 11, 2022
During development, nephron structures are derived from a SIX2+ stem cell population. After 36 weeks of gestation, these cells are exhausted, and no new nephrons are formed. We have previously described a non-invasive strategy...