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NASH limits anti-tumour surveillance in immunotherapy-treated HCC
Dominik Pfister, Nicolás Gonzalo Núñez, Roser Pinyol, Olivier Govaere, Matthias Pinter, Marta Szydlowska, Revant Gupta, Mengjie Qiu, Aleksandra Deczkowska, Assaf Weiner, Florian Müller, Ankit Sinha, Ekaterina Friebel, Thomas Engleitner, Daniela Lenggenhager, Anja Moncsek, Danijela Heide, Kristin Stirm, Jan Kosla, Eleni Kotsiliti, Valentina Leone, Michael Dudek, Suhail Yousuf, Donato Inverso, Indrabahadur Singh, Ana Teijeiro, Florian Castet, Carla Montironi, Philipp K. Haber, Dina Tiniakos, Pierre Bedossa, Simon Cockell, Ramy Younes, Michele Vacca, Fabio Marra, Jörn M. Schattenberg, Michael Allison, Elisabetta Bugianesi, Vlad Ratziu, Tiziana Pressiani, Antonio D’Alessio, Nicola Personeni, Lorenza Rimassa, Ann K. Daly, Bernhard Scheiner, Katharina Pomej, Martha M. Kirstein, Arndt Vogel, Markus Peck-Radosavljevic, Florian Hucke, Fabian Finkelmeier, Oliver Waidmann, Jörg Trojan, Kornelius Schulze, Henning Wege, Sandra Koch, Arndt Weinmann, Marco Bueter, Fabian Rössler, Alexander Siebenhüner, Sara De Dosso, Jan-Philipp Mallm, Viktor Umansky, Manfred Jugold, Tom Luedde, Andrea Schietinger, Peter Schirmacher, Brinda Emu, Hellmut G. Augustin, Adrian Billeter, Beat Müller-Stich, Hiroto Kikuchi, Dan G. Duda, Fabian Kütting, Dirk-Thomas Waldschmidt, Matthias Philip Ebert, Nuh Rahbari, Henrik E. Mei, Axel Ronald Schulz, Marc Ringelhan, Nisar Malek, Stephan Spahn, Michael Bitzer, Marina Ruiz de Galarreta, Amaia Lujambio, Jean-Francois Dufour, Thomas U. Marron, Ahmed Kaseb, Masatoshi Kudo, Yi-Hsiang Huang, Nabil Djouder, Katharina Wolter, Lars Zender, Parice N. Marche, Thomas Decaens, David J. Pinato, Roland Rad, Joachim C. Mertens, Achim Weber, Kristian Unger, Felix Meissner, Susanne Roth, Zuzana Macek Jilkova, Manfred Claassen, Quentin M. Anstee, Ido Amit, Percy Knolle, Burkhard Becher, Josep M. Llovet, Mathias Heikenwalder
Apr 14, 2021
Abstract: Hepatocellular carcinoma (HCC) can have viral or non-viral causes1–5. Non-alcoholic steatohepatitis (NASH) is an important driver of HCC. Immunotherapy has been approved for treating HCC, but biomarker-based...
Impact of global PTP1B deficiency on the gut barrier permeability during NASH in mice.
Carmen Rubio, Marta Puerto, Juan J García-Rodríquez, Van B Lu, Irma García-Martínez, Rosa Alén, Patricia Sanmartín-Salinas, M Val Toledo-Lobo, Jorge Saiz, Javier Ruperez, Coral Barbas, Luis Menchén, Fiona M Gribble, Frank Reimann, Luis G Guijarro, Jose M Carrascosa, Ángela M Valverde
May 05, 2020
OBJECTIVE:Non-alcoholic steatohepatitis (NASH) is characterized by a robust pro-inflammatory component at both hepatic and systemic levels together with a disease-specific gut microbiome signature. Protein tyrosine phosphatase...
Published by: Molecular metabolism
NASH limits anti-tumour surveillance in immunotherapy-treated HCC.
Dominik Pfister, Nicolás Gonzalo Núñez, Roser Pinyol, Olivier Govaere, Matthias Pinter, Marta Szydlowska, Revant Gupta, Mengjie Qiu, Aleksandra Deczkowska, Assaf Weiner, Florian Müller, Ankit Sinha, Ekaterina Friebel, Thomas Engleitner, Daniela Lenggenhager, Anja Moncsek, Danijela Heide, Kristin Stirm, Jan Kosla, Eleni Kotsiliti, Valentina Leone, Michael Dudek, Suhail Yousuf, Donato Inverso, Indrabahadur Singh, Ana Teijeiro, Florian Castet, Carla Montironi, Philipp K Haber, Dina Tiniakos, Pierre Bedossa, Simon Cockell, Ramy Younes, Michele Vacca, Fabio Marra, Jörn M Schattenberg, Michael Allison, Elisabetta Bugianesi, Vlad Ratziu, Tiziana Pressiani, Antonio D'Alessio, Nicola Personeni, Lorenza Rimassa, Ann K Daly, Bernhard Scheiner, Katharina Pomej, Martha M Kirstein, Arndt Vogel, Markus Peck-Radosavljevic, Florian Hucke, Fabian Finkelmeier, Oliver Waidmann, Jörg Trojan, Kornelius Schulze, Henning Wege, Sandra Koch, Arndt Weinmann, Marco Bueter, Fabian Rössler, Alexander Siebenhüner, Sara De Dosso, Jan-Philipp Mallm, Viktor Umansky, Manfred Jugold, Tom Luedde, Andrea Schietinger, Peter Schirmacher, Brinda Emu, Hellmut G Augustin, Adrian Billeter, Beat Müller-Stich, Hiroto Kikuchi, Dan G Duda, Fabian Kütting, Dirk-Thomas Waldschmidt, Matthias Philip Ebert, Nuh Rahbari, Henrik E Mei, Axel Ronald Schulz, Marc Ringelhan, Nisar Malek, Stephan Spahn, Michael Bitzer, Marina Ruiz de Galarreta, Amaia Lujambio, Jean-Francois Dufour, Thomas U Marron, Ahmed Kaseb, Masatoshi Kudo, Yi-Hsiang Huang, Nabil Djouder, Katharina Wolter, Lars Zender, Parice N Marche, Thomas Decaens, David J Pinato, Roland Rad, Joachim C Mertens, Achim Weber, Kristian Unger, Felix Meissner, Susanne Roth, Zuzana Macek Jilkova, Manfred Claassen, Quentin M Anstee, Ido Amit, Percy Knolle, Burkhard Becher, Josep M Llovet, Mathias Heikenwalder
May 05, 2021
Hepatocellular carcinoma (HCC) can have viral or non-viral causes1-5. Non-alcoholic steatohepatitis (NASH) is an important driver of HCC. Immunotherapy has been approved for treating HCC, but biomarker-based stratification of...
Random-settlement arbitration and the generalized Nash solution:
We study bilateral bargaining á la Nash (Econometrica 21:128–140, 1953) but where players face two sources of uncertainty when demands are mutually incompatible. First, there is complete breakdown of negotiations with players...
Random-settlement arbitration and the generalized Nash solution:
We study bilateral bargaining á la Nash (Econometrica 21:128–140, 1953) but where players face two sources of uncertainty when demands are mutually incompatible. First, there is complete breakdown of negotiations with players...
Climate change and modern slavery in public procurement
This is a summary of the report from the project entitled: Intersecting sustainabilities: Protecting both people and planet in public sector supply chains, based on research conducted by Michael Rogerson (University of Sussex)...
Climate change and modern slavery in public procurement
This is a summary of the report from the project entitled: Intersecting sustainabilities: Protecting both people and planet in public sector supply chains, based on research conducted by Michael Rogerson (University of Sussex)...
The Grizzly, April 22, 2004
Lauren A. Perotti, Lindsey Fund, Kyle Kauffman, Brandie Salenetri, Whitney Roper, Michael Castiglione, Kelly Gray, Johanna Nash, Brian Grzymkowski, Bart Brooks, Monica Delaney, Marie DiFeliciantonio, Bill Stiles, Eden Swick
Jan 01, 0001
A Booming Economy Gives Way to a Promising Job Outlook Spotlights on 2004 Salutatorians: Jacqueline Carrick and Quinn Dinsmore Politics in Action: Photo Essay Opinions: Business Degree = Job?; "Cool" Defined; Condoleeza Rice...
Ursinus College Collegeville Pennsylvania newspaper softball Erin Skinner baseball Tommy Herrmann Ryan Bown gospel choir Concert Band Dance Company Donald Trump theater Spring Fling Nicole Borocci John Kerry Jacqueline Carrick Quinn Dinsmore cultural history Higher Education Liberal Studies Social History United States History
Published by: Ursinus College
The Grizzly, March 25, 2004
Lauren A. Perotti, Lindsey Fund, Brian Grzymkowski, Brandie Salenetri, Monica Delaney, Eden Swick, Kyle Kauffman, Tia Larese, Michael Castiglione, Johanna Nash
Jan 01, 0001
Ursinus College Bookstore now Under New Management Bombing in Madrid Causes Concern for Students' Safety The Real World Said Goodbye to Philadelphia It's Registration Time Again Opinions: How to Land that Perfect Job; Good...
Ursinus College Collegeville Pennsylvania newspaper Basketball softball Dennis Stanton Airband Habitat for Humanity MTV bookstore cultural history Higher Education Liberal Studies Social History United States History
Published by: Ursinus College
The Grizzly, February 5, 2004
Lauren A. Perotti, Lindsey Fund, Quinn Dinsmore, Bart Brooks, Monica Delaney, Johanna Nash, Kelly Gray, Brandie Salenetri, Dana D. Yancey, Kyle Kauffman, Glenn Carter
Jan 01, 0001
Take Notice of New Member Education Standards AES Team with Upromise to Help Ease the Repayment of Student Loans Unpredictable Democratic Primaries Myrin Library Update: Media Services Re-opens Opinions: New Member...
Ursinus College Collegeville Pennsylvania newspaper lacrosse pledging American Education Services cultural history Higher Education Liberal Studies Social History United States History
Published by: Ursinus College
On Distributed Scheduling of Flexible Demand and Nash Equilibria in the Electricity Market
This paper presents a novel game theory approach for large-scale deployment of price-responsive electrical appliances. In the proposed distributed control scheme, each appliance independently schedules its power consumption on...
The Grizzly, February 19, 2004
Lauren A. Perotti, Lindsey Fund, Kerri Landis, Tia Larese, Kelly Gray, Monica Delaney, Johanna Nash, Antwan Wolaniuk, Greg Pellish, Brandie Salenetri, Brian Grzymkowski, Bill Stiles, Kyle Kauffman, Michael Castiglione
Jan 01, 0001
Campus Safety and S.E.R.V. to Sponsor Lecture at Ursinus College Ursinus Club Spotlight: Campus Activities Board Impress Recruiters at the 2004 Ursinus College Job & Internship Fair Sign the Beam! Opinions: Ridiculous...
Ursinus College Collegeville Pennsylvania newspaper gymnastics Basketball Dan Luciano Performing Arts Center Campus Activities Board campus safety cultural history Higher Education Liberal Studies Social History United States History
Published by: Ursinus College
Genome-wide association analysis identifies variants associated with nonalcoholic fatty liver disease that have distinct effects on metabolic traits.
Elizabeth K Speliotes, Laura M Yerges-Armstrong, Jun Wu, Ruben Hernaez, Lauren J Kim, Cameron D Palmer, Vilmundur Gudnason, Gudny Eiriksdottir, Melissa E Garcia, Lenore J Launer, Michael A Nalls, Jeanne M Clark, Braxton D Mitchell, Alan R Shuldiner, Johannah L Butler, Marta Tomas, Udo Hoffmann, Shih-Jen Hwang, Joseph M Massaro, Christopher J O'Donnell, Dushyant V Sahani, Veikko Salomaa, Eric E Schadt, Stephen M Schwartz, David S Siscovick, NASH CRN, GIANT Consortium, MAGIC Investigators, Benjamin F Voight, J Jeffrey Carr, Mary F Feitosa, Tamara B Harris, Caroline S Fox, Albert V Smith, WH Linda Kao, Joel N Hirschhorn, Ingrid B Borecki, GOLD Consortium
Jan 23, 2018
Nonalcoholic fatty liver disease (NAFLD) clusters in families, but the only known common genetic variants influencing risk are near PNPLA3. We sought to identify additional genetic variants influencing NAFLD using genome-wide...
Adaptor Proteins Signal Transducing Adult Aged Aged 80 and over Blood Glucose Case-Control Studies Chondroitin Sulfate Proteoglycans Cohort Studies Fatty Liver Genome-Wide Association Study Humans Insulin Lectins C-Type LIPASE Male Membrane Proteins Middle Aged Mutation Missense Nerve Tissue Proteins Neurocan non-alcoholic fatty liver disease Polymorphism Single Nucleotide Quantitative Trait Loci Tomography X-Ray Computed
On Distributed Scheduling of Flexible Demand and Nash Equilibria in the Electricity Market
This paper presents a novel game theory approach for large-scale deployment of price-responsive electrical appliances. In the proposed distributed control scheme, each appliance independently schedules its power consumption on...
The Grizzly, October 16, 2003
Lauren A. Perotti, Lindsey Fund, Ellen Calhoun, Turquoise Johnson, Maria Rivera, Vincent DePasquale, Amanda Bryman, Monica Delaney, Bart Brooks, Stephanie Tammany, Brandie Salenetri, Trevor Mohr, Kyle Kauffman, Alexis Witt, Susannah Fisher, Crystal McCarney, Nicole Borocci, Eden Swick, Kristen Grimmel, Jon Herting, Bill Stiles, Marie DiFeliciantonio, Rebecca Cohen, Katherine Jones, Johanna Nash, Brendan Bell
Jan 01, 0001
Feeling Drained for a Good Cause: Omega Chi Blood Drive CAB Laugh-off Left Students Rolling in the Aisles UC in the City Program Announces Easier Access to Philly Political Pagemakers: Democratic Candidates for President ...
Ursinus College Collegeville Pennsylvania newspaper Volleyball Rugby field hockey Soccer Swimming Sue Hadfield Homecoming Philip Zwerling theater sycamore tree Patterson Field Myrin Library Omega Chi Philadelphia Sprankle Hall forensics team Campus Activities Board cultural history Higher Education Liberal Studies Social History United States History
Published by: Ursinus College
Focality and Asymmetry in Multi-battle Contests
This article examines the influence of focality in Colonel Blotto games with a lottery contest success function, where the equilibrium is unique and in pure strategies. We hypothesize that the salience of battlefields affects...
Mapping neuronal inputs to Kiss1 neurons in the arcuate nucleus of the mouse.
The normal function of the mammalian reproductive axis is strongly influenced by physiological, metabolic and environmental factors. Kisspeptin neuropeptides, encoded by the Kiss1 gene, are potent regulators of the mammalian...
The Grizzly, November 13, 2003
Lauren A. Perotti, Lindsey Fund, Turquoise Johnson, Lauren Melton, Meg Gallagher, Vincent DePasquale, Peter Bregman, Kyle Kauffman, Brandie Salenetri, Ellen Calhoun, Anthony Virtue, Johanna Nash, Eden Swick, Maria Rivera, John Herting, Kimberly Salmon, Brendan Bell, Alexis Witt, Nicole Frates, Stephanie Tammany, Ray Baker, Bart Brooks, Meghan Jarrett, Noelle Bolletino, Patricia Gruver
Jan 01, 0001
The Power of Puppets: Spiral Q at Ursinus Registration Frustration Philly Re-elects John Street as Mayor First Injectable Male Contraceptive Campus Connection: Spotlight on NYU and Student Suicide Rush Begins at Ursinus ...
Ursinus College Collegeville Pennsylvania newspaper Football field hockey Soccer recycling Halloween career planning Randy Pogue John Street cell phones pledging Spiral Q class registration cultural history Higher Education Liberal Studies Social History United States History
Published by: Ursinus College
Focality and Asymmetry in Multi-battle Contests
This article examines the influence of focality in Colonel Blotto games with a lottery contest success function, where the equilibrium is unique and in pure strategies. We hypothesize that the salience of battlefields affects...
Joanne Doran, Cara Walters, Victoria Kyle, Peter Wooding, Rebecca Hammett-Burke, William Henry Colledge
May 05, 2016
The Grizzly, November 8, 2007
Matt Flyntz, Lane Taylor, Salia Zouande, Caitlin Dalik, Ashley McComeskey, Ashley Higgins, Andy Lane, Zach Shamberg, Kristin O'Brassill, Laura Glace, Katie Callahan, Zakary Arnhold, Christopher Schaeffer, Kelsey Threatte, Alex Ernst, Jason Davis, Matt Campbell
Jan 01, 0001
Campus Safety Offers Tips to Stay Alert, Aware "Lost Boy" Speaks on Civil War in Sudan, Genocide in Darfur "Car for a Cause" Pulls Into Ursinus UC Democrats Kick Off Montgomery County Campaign Invasion If Nobody Speaks of...
Ursinus College Collegeville Pennsylvania newspaper campus safety Michael Kuch Kristen Collins College Democrats anti-genocide coalition Smoking Kyle Rush Soccer Football cultural history Higher Education Liberal Studies Social History United States History
Published by: Ursinus College
Unmet needs in pediatric NAFLD research
Pediatric nonalcoholic fatty liver disease (NAFLD) is common disorder that has complex pathophysiology and unquantified clinical significance. Though there have been major advances in the field, there is much yet to be...
Nonalcoholic fatty liver disease fatty liver disease hepatology Microbiome Pediatrics Adolescent Biomedical Research Cardiovascular Diseases Child Child Preschool Dysbiosis Gastrointestinal Microbiome Host Microbial Interactions Humans Infant Infant Newborn Metabolic Syndrome non-alcoholic fatty liver disease Risk Assessment
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