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Results: 12127
Mi-2/NuRD complex protects stem cell progeny from mitogenic Notch signaling.
To progress towards differentiation, progeny of stem cells need to extinguish expression of stem-cell maintenance genes. Failures in such mechanisms can drive tumorigenesis. In Drosophila neural stem cell (NSC) lineages...
D. melanogaster Notch NuRD Complex Chromosomes developmental biology Gene Expression Stem Cells Adenosine Triphosphatases Animals Autoantigens Basic Helix-Loop-Helix Transcription Factors Carcinogenesis Cell Differentiation Cell Lineage Cell Proliferation Drosophila Proteins Drosophila melanogaster Gene Expression Regulation Developmental Humans Hyperplasia Models Biological Neural Stem Cells Neurons Protein Binding Receptors Notch Repressor Proteins Signal Transduction
Almost global convergence to practical synchronization in the generalized Kuramoto model on networks over the n-sphere
Abstract From the flashing of fireflies to autonomous robot swarms, synchronization phenomena are ubiquitous in nature and technology. They are commonly described by the Kuramoto model that, in...
Hydration and N-acetyl-l-cysteine alter the microstructure of human nail and bovine hoof
This work aimed to (a) characterize the microstructure and porosity of human nail and bovine hoof by mercury intrusion porosimetry and SEM image analysis, (b) study the effects of hydration and of N-acetyl-l-cysteine treatment...
Corinna PMG 655 (= P.Oxy. 2370) fr.1 l. 13 κόσμ[εισα λόγυ]ς
L Prauscello
May 02, 2017
0. Fr. 1 of P.Oxy. 2370 (= MP3
249; LDAB 573), published by Lobel in 1956, is so far the only papyrus
fragment among those extant in Boeotian dialect1
whose authorship can be securely ascribed to
Corinna thanks to the overlap...
Floer Simple Manifolds and L-Space Intervals
An oriented three-manifold with torus boundary admits either no L-space Dehn filling, a unique L-space filling, or an interval of L-space fillings. In the latter case, which we call “Floer simple,” we construct an invariant...
Hydration and N-acetyl-l-cysteine alter the microstructure of human nail and bovine hoof
This work aimed to (a) characterize the microstructure and porosity of human nail and bovine hoof by mercury intrusion porosimetry and SEM image analysis, (b) study the effects of hydration and of N-acetyl-l-cysteine treatment...
Eugene L. Opie, 1910
The Rockefeller University
Jan 01, 0001
Eugene L. Opie, M.D. Inflammation
Lecture delivered February 10th, 1910
Bacterial Infection inflammation reaction macrophage Lymphatic Vessels polynuclear leucocytes enzyme
Published by: J.B. Lippincott Company
L q -spectra of self-affine measures
Abstract: We study L q -spectra of planar self-affine measures generated by diagonal matrices. We introduce a new technique for constructing and understanding examples based on combinatorial estimates for the exponential growth...
S-2-Amino-4-cyanobutanoic acid (β-cyanomethyl-L-Ala) as an atom-efficient solubilising synthon for L-glutamine
Glutamine (Gln) is often a difficult amino acid to incorporate during solution-phase peptide synthesis, owing to poor solubility and unwanted dehydrations as side-reactions. Current approaches to solving these problems are...
Endothelial Cell Indoleamine 2, 3-Dioxygenase 1 Alters Cardiac Function After Myocardial Infarction Through Kynurenine.
Nada Joe Melhem, Mouna Chajadine, Ingrid Gomez, Kiave-Yune Howangyin, Marion Bouvet, Camille Knosp, Yanyi Sun, Marie Rouanet, Ludivine Laurans, Olivier Cazorla, Mathilde Lemitre, José Vilar, Ziad Mallat, Alain Tedgui, Hafid Ait-Oufella, Jean-Sébastien Hulot, Jacques Callebert, Jean-Marie Launay, Jeremy Fauconnier, Jean-Sébastien Silvestre, Soraya Taleb
Dec 07, 2020
BACKGROUND: Ischemic cardiovascular diseases, particularly acute myocardial infarction (MI), is one of the leading causes of mortality worldwide. Indoleamine 2, 3-dioxygenase 1 (IDO) catalyzes 1 rate-limiting step of...
Frank L. Horsfall, Jr., 1952
The Rockefeller University
Jan 01, 0001
Frank L. Horsfall, Jr. Experiments on chemical alteration of virus infections.
Lecture delivered November 20, 1952
Posted with permission
Published by: Academic Press Inc., Publishers
Encompassing new use cases - level 3.0 of the HUPO-PSI format for molecular interactions.
M Sivade Dumousseau, D Alonso-López, M Ammari, G Bradley, NH Campbell, A Ceol, G Cesareni, C Combe, J De Las Rivas, N Del-Toro, J Heimbach, H Hermjakob, I Jurisica, M Koch, L Licata, RC Lovering, DJ Lynn, BHM Meldal, G Micklem, S Panni, P Porras, S Ricard-Blum, B Roechert, L Salwinski, A Shrivastava, J Sullivan, N Thierry-Mieg, Y Yehudi, K Van Roey, S Orchard
Sep 08, 2018
BACKGROUND: Systems biologists study interaction data to understand the behaviour of whole cell systems, and their environment, at a molecular level. In order to effectively achieve this goal, it is critical that researchers...
Rapid sensing of l-leucine by human and murine hypothalamic neurons
Nicholas Heeley, Peter Kirwan, Tamana Darwish, Marion Arnaud, Mark L Evans, Florian T Merkle, Frank Reimann, Fiona M Gribble, Clemence Blouet
Apr 05, 2018
OBJECTIVE: Dietary proteins are sensed by hypothalamic neurons and strongly influence multiple aspects of metabolic health, including appetite, weight gain, and adiposity. However, little is known about the mechanisms by which...
S-2-Amino-4-cyanobutanoic acid (β-cyanomethyl-L-Ala) as an atom-efficient solubilising synthon for L-glutamine
Glutamine (Gln) is often a difficult amino acid to incorporate during solution-phase peptide synthesis, owing to poor solubility and unwanted dehydrations as side-reactions. Current approaches to solving these problems are...
Microbial regulation of the L cell transcriptome.
Tulika Arora, Rozita Akrami, Ramona Pais, Linda Bergqvist, Bengt R Johansson, Thue W Schwartz, Frank Reimann, Fiona M Gribble, Fredrik Bäckhed
Apr 26, 2018
L cells are an important class of enteroendocrine cells secreting hormones such as glucagon like peptide-1 and peptide YY that have several metabolic and physiological effects. The gut is home to trillions of bacteria affecting...
On the Shores of Politics
RORY O'BRYEN
Apr 20, 2018
This article explores discourses surrounding the modernisation of the state and the formation of national literature in nineteenth‐century Colombia, examining the racism at the heart of both, particularly in their representation...
Riociguat reduces infarct size and post-infarct heart failure in mouse hearts
Carmen Methner, Guido Buonincontri, Chou-Hui Hu, Ana Vujic, Axel Kretschmer, Stephen Sawiak, Adrian Carpenter, Johannes-Peter Stasch, Thomas Krieg
Oct 16, 2020
AIM: Stimulation of the nitric oxide (NO)--soluble guanylate (sGC)--protein kinase G (PKG) pathway confers protection against acute ischaemia/reperfusion injury, but more chronic effects in reducing post-myocardial infarction...
Animals Biomarkers Echocardiography Guanylate Cyclase Heart Failure Hemodynamics Image Processing Computer-Assisted Magnetic Resonance Imaging Male Mice Mice Inbred C57BL Myocardial Infarction Myocardial Reperfusion Injury Positron-Emission Tomography Pyrazoles Pyrimidines Receptors Cytoplasmic and Nuclear Soluble Guanylyl Cyclase
Dr. Herman L. Frick Promotion
Winthrop News Service
Jan 01, 0001
Dr. Herman L. Frick, superintendent of Winthrop Training School, was named Director of Teacher Education and Graduate Study at Winthrop in October 1946 Dr. Frick worked at Winthrop from 1941 to 1949 except for 1944-1946 when he...
Winthrop College of Education Winthrop Training School Higher Education Teacher Education and Professional Development
Published by: Winthrop University
Predicting risk of cardiovascular events 1 to 3 years post-myocardial infarction using a global registry.
Stuart J Pocock, David Brieger, John Gregson, Ji Y Chen, Mauricio G Cohen, Shaun G Goodman, Christopher B Granger, Richard Grieve, Jose C Nicolau, Tabassome Simon, Dirk Westermann, Satoshi Yasuda, Katarina Hedman, Kirsten L Rennie, Karolina Andersson Sundell, TIGRIS Study Investigators
Jan 16, 2020
BACKGROUND: Risk prediction tools are lacking for patients with stable disease some years after myocardial infarction (MI). HYPOTHESIS: A practical long-term cardiovascular risk index can be developed. METHODS: The long-Term...
M2 Do patients and informal carers agree on symptom burden in advanced copd?
Objective: Accurate informal carer assessment of patient symptoms is likely to be valuable for decision-making in managing the high symptom burden of chronic obstructive pulmonary disease (COPD) in the home setting. Few studies...
Hyperpolarized [1,4-13C2]Fumarate Enables Magnetic Resonance-Based Imaging of Myocardial Necrosis.
Jack J Miller, Angus Z Lau, Per Mose Nielsen, Giles McMullen-Klein, Andrew J Lewis, Nichlas Riise Jespersen, Vicky Ball, Ferdia A Gallagher, Carolyn A Carr, Christoffer Laustsen, Hans Erik Bøtker, Damian J Tyler, Marie A Schroeder
Feb 11, 2019
OBJECTIVES: The aim of this study was to determine if hyperpolarized [1,4-13C2]malate imaging could measure cardiomyocyte necrosis after myocardial infarction (MI). BACKGROUND: MI is defined by an acute burst of cellular...
cardiac MRI Energy Metabolism hyperpolarized MR Magnetic Resonance Spectroscopy Necrosis Animals Carbon Isotopes Carbon-13 Magnetic Resonance Spectroscopy Contrast Media Energy Metabolism Fumarates Isolated Heart Preparation Magnetic Resonance Imaging Cine Malates Male Molecular Imaging Myocardial Infarction Myocytes Cardiac Necrosis Predictive Value of Tests Rats Wistar
L(3)mbt and the LINT complex safeguard cellular identity in the Drosophila ovary.
Maintenance of cellular identity is essential for tissue development and homeostasis. At the molecular level, cell identity is determined by the coordinated activation and repression of defined sets of genes. The tumor...
Do patients and carers agree on symptom burden in advanced COPD?
Emma Mi, Ella Mi, Gail Ewing, Patrick White, Ravi Mahadeva, A Carole Gardener, Morag Farquhar
Apr 16, 2019
OBJECTIVE: Accurate informal carer assessment of patient symptoms is likely to be valuable for decision making in managing the high symptom burden of COPD in the home setting. Few studies have investigated agreement between...
COPD agreement Informal carers symptom Adaptation Psychological Aged Caregivers Cost of Illness Cross-Sectional Studies Female Health Knowledge Attitudes practice health status Humans Male Mental Health Middle Aged Patients Prognosis Prospective Studies Pulmonary Disease Chronic Obstructive Quality of life Risk Factors Severity of Illness Index
L<sup>q</sup>-spectra of self-affine measures
Abstract
We study L
q
-spectra of planar...
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