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The Bull-James assembly
Chiral molecules are widely used in many fields of research and so practically simple, accurate methods to measure their enantiopurities are required. This review's initial focus is on one such method, the Bull-James...
The Bull-James assembly
Chiral molecules are widely used in many fields of research and so practically simple, accurate methods to measure their enantiopurities are required. This review's initial focus is on one such method, the Bull-James...
Organoid Sample Preparation and Extraction for LC-MS Peptidomics.
Emily L Miedzybrodzka, Rachel E Foreman, Sam G Galvin, Pierre Larraufie, Amy L George, Deborah A Goldspink, Frank Reimann, Fiona M Gribble, Richard G Kay
Mar 18, 2021
This protocol describes the peptidomic analysis of organoid lysates, FACS-purified cell populations, and 2D culture secretions by liquid chromatography mass spectrometry (LC-MS). Currently, most peptides are quantified by ELISA...
James Darnell, Jr., 1973
The Rockefeller University
Jan 01, 0001
James E. Darnell, Jr. The origins of mRNA and the structure of the mammalian chromosome
Lecture delivered September 20, 1973
Posted with permission
Published by: Academic Press
Research priorities in mesothelioma
RJ Stephens, C Whiting, K Cowan, James Lind Alliance Mesothelioma Priority Setting Partnership Steering Committee
Aug 17, 2021
BACKGROUND: In the UK, despite the import and use of all forms of asbestos being banned more than 15 years ago, the incidence of mesothelioma continues to rise. Mesothelioma is almost invariably fatal, and more research is...
LC–MS Lipidomics
Typical lipidomics methods incorporate a liquid−liquid extraction with LC−MS quantitation; however, the classic sample extraction methods are not high-throughput and do not perform well at extracting the full range of lipids...
Henry James At Any Rate
RM Wilson
Mar 13, 2017
This essay discusses James’s prefaces to the New York Edition as instances of the development of the form of the preface for James’s critical purposes. In particular, it focuses on the deployment of James’s frequent and...
Bilirubin deficiency renders mice susceptible to hepatic steatosis in the absence of insulin resistance.
Weiyu Chen, Sergey Tumanov, Daniel J Fazakerley, James Cantley, David E James, Louise L Dunn, Taqi Shaik, Cacang Suarna, Roland Stocker
Nov 05, 2021
BACKGROUND & AIMS: Plasma concentrations of bilirubin, a product of heme catabolism formed by biliverdin reductase A (BVRA), inversely associate with the risk of metabolic diseases including hepatic steatosis and diabetes...
Westminster Abbey Organist James O'Donnell Featured at Feb. 14 Recital
Winthrop University
Jan 01, 0001
Westminster Abbey Organist James O'Donnell looks forward to playing Winthrop's famed D.B. Johnson Memorial Organ for the Feb. 14 concert at Byrnes Auditorium. Tickets are $10 for the general public and $5 for those over 65 or...
Published by: Winthrop University
Noradrenergic-dependent functions are associated with age-related locus coeruleus signal intensity differences.
Kathy Y Liu, Rogier A Kievit, Kamen A Tsvetanov, Matthew J Betts, Emrah Düzel, James B Rowe, Robert Howard, Dorothea Hämmerer
May 06, 2020
The locus coeruleus (LC), the origin of noradrenergic modulation of cognitive and behavioral function, may play an important role healthy ageing and in neurodegenerative conditions. We investigated the functional significance of...
Published by: Nature Communications
Measurement of the total angiotensinogen and its reduced and oxidised forms in human plasma using targeted LC-MS/MS.
Lina A Dahabiyeh, David Tooth, Robin W Carrell, Randy J Read, Yahui Yan, Fiona Broughton Pipkin, David A Barrett
Dec 11, 2018
Angiotensinogen (AGT) is a critical protein in the renin-angiotensin-aldosterone system and may have an important role in the pathogenesis of pre-eclampsia. The disulphide linkage between cysteines 18 and 138 has a key role in...
‘The most remarkable man’
Kevin J Edwards
Apr 04, 2022
ABSTRACT: The year 2021 marked the bicentenary of the birth of James Croll (1821–1890), the self‐educated son of a crofter‐stonemason, whose life was characterised by a dizzying range of occupations and homes, poor health and...
James Croll and geological archives
ABSTRACT James Croll's Physical Theory of Secular Changes of Climate emerged during an age of revolution in geology that included the rise of the glacial theory and the search for its underlying...
Three Winthrop Alumni Selected as 2016 James E. Clyburn Political Fellows
Winthrop University
Jan 01, 0001
The 2016 James E. Clyburn Political Fellowship will develop the next generation of leadership and talent within the South Carolina Democratic Party. Adams, Allen and Jeter will participate in five three-day seminars/training...
Published by: Winthrop University
Functionalized graphene oxide tablets for sample preparation of drugs in biological fluids
Zeynab Zohdijamil, Mahdi Hashemi, Abbi Abdel-Rehim, Karthik Laxman, Abdusalam Uheida, Joydeep Dutta, Mohamed Abdel-Rehim
Jun 04, 2021
In this work, graphene oxide-based tablets (GO-Tabs) were prepared by applying a thin layer of functionalized GO on a polyethylene substrate. The GO was functionalized with amine groups (-NH2 ) by poly(ethylene...
Westminster Abbey Organist James O'Donnell to Give Recital on Winthrop's Famed Organ on Feb. 14
Winthrop University
Jan 01, 0001
James O'Donnell, world renowned organist and master of the choristers of Westminster Abbey in London, England, will perform a recital on Winthrop's famed organ. The recital is the first of The Friends of the D.B. Johnson...
Published by: Winthrop University
Into the Wood
Tamara L Follini
Jan 08, 2020
Abstract: This article performs a close reading of James’s 1874/1875 neglected Italian travelogue “Ravenna,” approaching it as a disguised parable of difficulties he confronted as an aspiring writer, in particular those...
Isolation, identification and quantitation of hydroxycinnamic acid conjugates, potential platform chemicals, in the leaves and stems of Miscanthus x giganteus using LC-ESI-MS(n)
Miscanthus x giganteus is a source of platform chemicals and bioethanol through fermentation. Cinnamates in leaves and stems were analysed by LC-ESI-MS(n). Free phenols were extracted and separated chromatographically. More than...
IPR Policy Brief - The cost of binge drinking in the UK
Much is known about the effects and costs of sustained heavy drinking, such as the increased risk of chronic disease and injury to individuals, the damage to social relationships and the additional burden on public services...
Published by: University of Bath
Isolation, identification and quantitation of hydroxycinnamic acid conjugates, potential platform chemicals, in the leaves and stems of Miscanthus x giganteus using LC-ESI-MS(n)
Miscanthus x giganteus is a source of platform chemicals and bioethanol through fermentation. Cinnamates in leaves and stems were analysed by LC-ESI-MS(n). Free phenols were extracted and separated chromatographically. More than...
An in vivo probabilistic atlas of the human locus coeruleus at ultra-high field.
Rong Ye, Catarina Rua, Claire O'Callaghan, P Simon Jones, Frank H Hezemans, Sanne S Kaalund, Kamen A Tsvetanov, Christopher T Rodgers, Guy Williams, Luca Passamonti, James B Rowe
Oct 20, 2020
Early and profound pathological changes are evident in the locus coeruleus (LC) in dementia and Parkinson's disease, with effects on arousal, attention, cognitive and motor control. The LC can be identified in vivo using...
IPR Policy Brief - The cost of binge drinking in the UK
Much is known about the effects and costs of sustained heavy drinking, such as the increased risk of chronic disease and injury to individuals, the damage to social relationships and the additional burden on public services...
Published by: University of Bath
A novel method for quantification of gemcitabine and its metabolites 2',2'-difluorodeoxyuridine and gemcitabine triphosphate in tumour tissue by LC-MS/MS
Tashinga E Bapiro, Frances M Richards, Mae A Goldgraben, Kenneth P Olive, Basetti Madhu, Kristopher K Frese, Natalie Cook, Michael A Jacobetz, Donna-Michelle Smith, David A Tuveson, John R Griffiths, Duncan I Jodrell
Nov 30, 2017
PURPOSE: To develop a sensitive analytical method to quantify gemcitabine (2',2'-difluorodeoxycytidine, dFdC) and its metabolites 2',2'-difluorodeoxyuridine (dFdU) and 2',2'-difluorodeoxycytidine-5'-triphosphate (dFdCTP)...
The Mystery of “Collaboration” in Henry James
This article argues for the importance of collaboration as a species of literary relation in Henry James’s work. Collaboration was increasingly popular towards the end of the nineteenth century, and yet, James’s interest...
James Lello
Apr 14, 2021
Health benefits of policies to reduce carbon emissions.
James Milner, Ian Hamilton, James Woodcock, Martin Williams, Mike Davies, Paul Wilkinson, Andy Haines
Oct 21, 2020
James Milner and colleagues argue that carefully considered policies to lower carbon emissions can also improve health, and we should use these benefits to push for strong climate action
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