Meta-analysis identifies common and rare variants influencing blood pressure and overlapping with metabolic trait loci.
Chunyu Liu,
Aldi T Kraja,
Jennifer A Smith,
Jennifer A Brody,
Nora Franceschini,
Joshua C Bis,
Kenneth Rice,
Alanna C Morrison,
Yingchang Lu,
Stefan Weiss,
Xiuqing Guo,
Walter Palmas,
Lisa W Martin,
Yii-Der Ida Chen,
Praveen Surendran,
Fotios Drenos,
James P Cook,
Paul L Auer,
Audrey Y Chu,
Ayush Giri,
Wei Zhao,
Johanna Jakobsdottir,
Li-An Lin,
Jeanette M Stafford,
Najaf Amin,
Hao Mei,
Jie Yao,
Arend Voorman,
CHD Exome+ Consortium,
ExomeBP Consortium,
GoT2DGenes Consortium,
T2D-GENES Consortium,
Martin G Larson,
Megan L Grove,
Albert V Smith,
Shih-Jen Hwang,
Han Chen,
Tianxiao Huan,
Gulum Kosova,
Nathan O Stitziel,
Sekar Kathiresan,
Nilesh Samani,
Heribert Schunkert,
Panos Deloukas,
Myocardial Infarction Genetics and CARDIoGRAM Exome Consortia,
Man Li,
Christian Fuchsberger,
Cristian Pattaro,
Mathias Gorski,
CKDGen consortium,
Charles Kooperberg,
George J Papanicolaou,
Jacques E Rossouw,
Jessica D Faul,
Sharon LR Kardia,
Claude Bouchard,
Leslie J Raffel,
André G Uitterlinden,
Oscar H Franco,
Ramachandran S Vasan,
Christopher J O'Donnell,
Kent D Taylor,
Kiang Liu,
Erwin P Bottinger,
Omri Gottesman,
E Warwick Daw,
Franco Giulianini,
Santhi Ganesh,
Elias Salfati,
Tamara B Harris,
Lenore J Launer,
Marcus Dörr,
Stephan B Felix,
Rainer Rettig,
Henry Völzke,
Eric Kim,
Wen-Jane Lee,
I-Te Lee,
Wayne H-H Sheu,
Krystal S Tsosie,
Digna R Velez Edwards,
Yongmei Liu,
Adolfo Correa,
David R Weir,
Uwe Völker,
Paul M Ridker,
Eric Boerwinkle,
Vilmundur Gudnason,
Alexander P Reiner,
Cornelia M van Duijn,
Ingrid B Borecki,
Todd L Edwards,
Aravinda Chakravarti,
Jerome I Rotter,
Bruce M Psaty,
Ruth JF Loos,
Myriam Fornage,
Georg B Ehret,
Christopher Newton-Cheh,
Daniel Levy,
Daniel I Chasman
Nov 20, 2017
Meta-analyses of association results for blood pressure using exome-centric single-variant and gene-based tests identified 31 new loci in a discovery stage among 146,562 individuals, with follow-up and meta-analysis in 180,726...