Search
Results: 272
CYP2D6 phenotype, tamoxifen, and risk of contralateral breast cancer in the WECARE Study.
Jennifer D Brooks, Elizabeth A Comen, Anne S Reiner, Irene Orlow, Siok F Leong, Xiaolin Liang, Lene Mellemkjær, Julia A Knight, Charles F Lynch, Esther M John, Leslie Bernstein, Meghan Woods, David R Doody, WECARE Study Collaborative Group, Kathleen E Malone, Jonine L Bernstein
Feb 18, 2019
BACKGROUND: Tamoxifen treatment greatly reduces a woman's risk of developing a second primary breast cancer. There is, however, substantial variability in treatment response, some of which may be attributed to germline genetic...
CYP2D6 Contralateral breast cancer Tamoxifen Adult Aged Antineoplastic Agents Hormonal Breast Neoplasms Case-Control Studies Cytochrome P-450 CYP2D6 Female Follow-Up Studies Humans Middle Aged Neoplasms Second Primary Pharmacogenomic Variants Polymorphism Single Nucleotide Tamoxifen Treatment Outcome
Societal Need for Interdisciplinary Ageing Research
Nicolas Cherbuin, Katsuya Iijima, Sebastiana Kalula, Rahul Malhotra, Lene Juel Rasmussen, Angelique Chan, Louise Lafortune, Sarah Harper, Xiaoying Zheng, David Lindeman, Erin Walsh, Rafat Hussain, Richard Burns, Maria Kristiansen, Ikuko Sugawara, Bokyung Son, Tomoki Tanaka, Stefanie Buckner, Jaco Hoffman, Marc Combrinck
Apr 14, 2021
Ageing is a global concern with major social, health, and economic implications. While individual countries seek to develop responses to immediate, pressing needs, international attention and collaboration is required to most...
Hormone receptor status of a first primary breast cancer predicts contralateral breast cancer risk in the WECARE study population
Anne S Reiner, Charles F Lynch, Julia S Sisti, Esther M John, Jennifer D Brooks, Leslie Bernstein, Julia A Knight, Li Hsu, Patrick Concannon, Lene Mellemkjær, Marc Tischkowitz, Robert W Haile, Ronglai Shen, Kathleen E Malone, Meghan Woods, Xiaolin Liang, Monica Morrow, Jonine L Bernstein
Jul 20, 2017
Abstract
Background
Previous population-based studies have described first primary breast cancer tumor characteristics and their association with contralateral breast cancer...
A Kallikrein 15 (KLK15) single nucleotide polymorphism located close to a novel exon shows evidence of association with poor ovarian cancer survival.
Jyotsna Batra, Christina M Nagle, Tracy O'Mara, Melanie Higgins, Ying Dong, Olivia L Tan, Felicity Lose, Lene Marie Skeie, Srilakshmi Srinivasan, Kelly L Bolton, Honglin Song, Susan J Ramus, Simon A Gayther, Paul DP Pharoah, Mary-Anne Kedda, Amanda B Spurdle, Judith A Clements
Jun 16, 2011
Tracing the origin of adult intestinal stem cells.
Jordi Guiu, Edouard Hannezo, Shiro Yui, Samuel Demharter, Svetlana Ulyanchenko, Martti Maimets, Anne Jørgensen, Signe Perlman, Lene Lundvall, Linn Salto Mamsen, Agnete Larsen, Rasmus H Olesen, Claus Yding Andersen, Lea Langhoff Thuesen, Kristine Juul Hare, Tune H Pers, Konstantin Khodosevich, Benjamin D Simons, Kim B Jensen
Apr 18, 2019
Hormone receptor status of a first primary breast cancer predicts contralateral breast cancer risk in the WECARE study population.
Anne S Reiner, Charles F Lynch, Julia S Sisti, Esther M John, Jennifer D Brooks, Leslie Bernstein, Julia A Knight, Li Hsu, Patrick Concannon, Lene Mellemkjær, Marc Tischkowitz, Robert W Haile, Ronglai Shen, Kathleen E Malone, Meghan Woods, Xiaolin Liang, Monica Morrow, Jonine L Bernstein, WECARE Study Collaborative Group
Jul 20, 2017
BACKGROUND: Previous population-based studies have described first primary breast cancer tumor characteristics and their association with contralateral breast cancer (CBC) risk. However, information on influential covariates...
Contralateral breast cancer estrogen receptor Hormone receptor population-based Progesterone receptor Adult Aged BRCA1 Protein BRCA2 Protein Breast Neoplasms Case-Control Studies Female Humans Middle Aged Mutation Neoplasm Grading Neoplasm Staging Population Surveillance Receptors Estrogen Receptors Progesterone Risk Factors SEER Program Tumor Burden
A systematic review of measurement properties of patient reported outcome measures in psoriatic arthritis
Pil Højgaard, Louise Klokker, Ana-Maria Orbai, Kim Holmsted, Else M Bartels, Ying Ying Leung, Niti Goel, Maarten de Wit, Dafna D Gladman, Philip J Mease, Lene Dreyer, Lars E Kristensen, Oliver FitzGerald, William Tillett, Laure Gossec, Philip Helliwell, Vibeke Strand, Alexis Ogdie, Caroline B Terwee, Robin Christensen
Apr 01, 2018
BACKGROUND: An updated psoriatic arthritis (PsA) core outcome set (COS) for randomized controlled trials (RCTs) was endorsed at the Outcome Measures in Rheumatology (OMERACT) meeting in 2016.
OBJECTIVES: To synthesize...
A case-control study of the joint effect of reproductive factors and radiation treatment for first breast cancer and risk of contralateral breast cancer in the WECARE study.
Jennifer D Brooks, John D Boice, Roy E Shore, Anne S Reiner, Susan A Smith, Leslie Bernstein, Julia A Knight, Charles F Lynch, Esther M John, Kathleen E Malone, Lene Mellemkjær, Rikke Langballe, Xiaolin Liang, Meghan Woods, Marc Tischkowitz, Patrick Concannon, Daniel O Stram, WECARE Study Collaborative Group
Oct 23, 2020
OBJECTIVE: To examined the impact of reproductive factors on the relationship between radiation treatment (RT) for a first breast cancer and risk of contralateral breast cancer (CBC). METHODS: The Women's Environmental Cancer...
A systematic review of measurement properties of patient reported outcome measures in psoriatic arthritis
Pil Højgaard, Louise Klokker, Ana-Maria Orbai, Kim Holmsted, Else M Bartels, Ying Ying Leung, Niti Goel, Maarten de Wit, Dafna D Gladman, Philip J Mease, Lene Dreyer, Lars E Kristensen, Oliver FitzGerald, William Tillett, Laure Gossec, Philip Helliwell, Vibeke Strand, Alexis Ogdie, Caroline B Terwee, Robin Christensen
Apr 01, 2018
BACKGROUND: An updated psoriatic arthritis (PsA) core outcome set (COS) for randomized controlled trials (RCTs) was endorsed at the Outcome Measures in Rheumatology (OMERACT) meeting in 2016.
OBJECTIVES: To synthesize...
Breast Cancer Family History and Contralateral Breast Cancer Risk in Young Women
Anne S Reiner, Julia Sisti, Esther M John, Charles F Lynch, Jennifer D Brooks, Lene Mellemkjær, John D Boice, Julia A Knight, Patrick Concannon, Marinela Capanu, Marc Tischkowitz, Mark Robson, Xiaolin Liang, Meghan Woods, David V Conti, David Duggan, Roy Shore, Daniel O Stram, Duncan C Thomas, Kathleen E Malone, Leslie Bernstein, WECARE Study Collaborative Group, Jonine L Bernstein
Dec 07, 2020
Purpose The Women's Environmental Cancer and Radiation Epidemiology (WECARE) study demonstrated the importance of breast cancer family history on contralateral breast cancer (CBC) risk, even for noncarriers of deleterious...
Adolescent Adult Age Factors BRCA1 Protein BRCA2 Protein Breast Neoplasms Canada Case-Control Studies Checkpoint Kinase 2 Denmark Fanconi Anemia Complementation Group N Protein Female Genetic Predisposition to Disease Genotype Humans Middle Aged Neoplasm Invasiveness Polymorphism Single Nucleotide Risk Factors United States
Determinants of diet and physical activity (DEDIPAC)
Johannes Brug, Hidde P van der Ploeg, Anne Loyen, Wolfgang Ahrens, Oliver Allais, Lene F Andersen, Greet Cardon, Laura Capranica, Sebastien Chastin, Ilse De Bourdeaudhuij, Marieke De Craemer, Alan Donnelly, Ulf Ekelund, Paul Finglas, Marion Flechtner-Mors, Antje Hebestreit, Thomas Kubiak, Massimo Lanza, Nanna Lien, Ciaran MacDonncha, Mario Mazzocchi, Pablo Monsivais, Marie Murphy, Mary Nicolaou, Ute Nöthlings, Donal J O'Gorman, Britta Renner, Gun Roos, Matthijs van den Berg, Matthias B Schulze, Jürgen M Steinacker, Karien Stronks, Dorothee Volkert, Jeroen Lakerveld, DEDIPAC consortium
Feb 13, 2018
The establishment of the Determinants of Diet and Physical Activity (DEDIPAC) Knowledge Hub, 2013–2016, was the first action taken by the ‘Healthy Diet for a Healthy Life’ European Joint Programming Initiative. DEDIPAC aimed to...
Flavonoid and lignan intake and pancreatic cancer risk in the European prospective investigation into cancer and nutrition cohort.
Esther Molina-Montes, María-José Sánchez, Raul Zamora-Ros, HB As Bueno-de-Mesquita, Petra A Wark, Mireia Obon-Santacana, Tilman Kühn, Verena Katzke, Ruth C Travis, Weimin Ye, Malin Sund, Alessio Naccarati, Amalia Mattiello, Vittorio Krogh, Caterina Martorana, Giovanna Masala, Pilar Amiano, José-María Huerta, Aurelio Barricarte, José-Ramón Quirós, Elisabete Weiderpass, Lene Angell Åsli, Guri Skeie, Ulrika Ericson, Emily Sonestedt, Petra H Peeters, Isabelle Romieu, Augustin Scalbert, Kim Overvad, Matthias Clemens, Heiner Boeing, Antonia Trichopoulou, Eleni Peppa, Pavlos Vidalis, Kay-Tee Khaw, Nick Wareham, Anja Olsen, Anne Tjønneland, Marie-Christine Boutroun-Rualt, Françoise Clavel-Chapelon, Amanda J Cross, Yunxia Lu, Elio Riboli, Eric J Duell
May 12, 2016
Pre-diagnostic meat and fibre intakes in relation to colorectal cancer survival in the European Prospective Investigation into Cancer and Nutrition
Heather A Ward, Teresa Norat, Kim Overvad, Christina C Dahm, H Bas Bueno-De-Mesquita, Mazda Jenab, Veronika Fedirko, Duijnhoven Fränzel JB van, Guri Skeie, Dora Romaguera-Bosch, Anne Tjønneland, Anja Olsen, Franck Carbonnel, Aurélie Affret, Marie-Christine Boutron-Ruault, Verena Katzke, Tilman Kühn, Krassimira Aleksandrova, Heiner Boeing, Antonia Trichopoulou, Pagona Lagiou, Christina Bamia, Domenico Palli, Sabina Sieri, Rosario Tumino, Alessio Naccarati, Amalia Mattiello, Petra H Peeters, Elisabete Weiderpass, Lene Angell Åsli, Paula Jakszyn, J Ramón Quirós, María-José Sánchez, Miren Dorronsoro, José-María Huerta, Aurelio Barricarte, Karin Jirström, Ulrika Ericson, Ingegerd Johansson, Björn Gylling, Kathryn E Bradbury, Kay-Tee Khaw, Nicholas John Wareham, Magdalena Stepien, Heinz Freisling, Neil Murphy, Amanda J Cross, Elio Riboli
Aug 09, 2017
Colorectal cancers Cancer survival Diets Cohorts European Prospective Investigation into Cancer and Nutrition
Published by: British Journal of Nutrition
Joint sequencing of human and pathogen genomes reveals the genetics of pneumococcal meningitis.
John A Lees, Bart Ferwerda, Philip HC Kremer, Nicole E Wheeler, Mercedes Valls Serón, Nicholas J Croucher, Rebecca A Gladstone, Hester J Bootsma, Nynke Y Rots, Alienke J Wijmega-Monsuur, Elisabeth AM Sanders, Krzysztof Trzciński, Anne L Wyllie, Aeilko H Zwinderman, Leonard H Van den Berg, Wouter Van Rheenen, Jan H Veldink, Zitta B Harboe, Lene F Lundbo, Lisette CPGM de Groot, Natasja M van Schoor, Nathalie van der Velde, Lars H Ängquist, Thorkild IA Sørensen, Ellen A Nohr, Alexander J Mentzer, Tara C Mills, Julian C Knight, Mignon Du Plessis, Susan Nzenze, Jeffrey N Weiser, Julian Parkhill, Shabir Madhi, Thomas Benfield, Anne von Gottberg, Arie van der Ende, Matthijs C Brouwer, Jeffrey C Barrett, Stephen D Bentley, Diederik van de Beek
Jul 25, 2019
Streptococcus pneumoniae is a common nasopharyngeal colonizer, but can also cause life-threatening invasive diseases such as empyema, bacteremia and meningitis. Genetic variation of host and pathogen is known to play a role in...
Unpacking the behavioural components and delivery features of early childhood obesity prevention interventions in the TOPCHILD Collaboration
Brittany J Johnson, Kylie E Hunter, Rebecca K Golley, Paul Chadwick, Angie Barba, Mason Aberoumand, Sol Libesman, Lisa Askie, Rachael W Taylor, Kristy P Robledo, Seema Mihrshahi, Denise A O'Connor, Alison J Hayes, Luke Wolfenden, Charles T Wood, Louise A Baur, Chris Rissel, Lukas P Staub, Sarah Taki, Wendy Smith, Michelle Sue-See, Ian C Marschner, David Espinoza, Jessica L Thomson, Junilla K Larsen, Vera Verbestel, Cathleen Odar Stough, Sarah-Jeanne Salvy, Sharleen L O'Reilly, Levie T Karssen, Finn E Rasmussen, Mary Jo Messito, Rachel S Gross, Maria Bryant, Ian M Paul, Li Ming Wen, Kylie D Hesketh, Carolina González Acero, Karen Campbell, Nina Cecilie Øverby, Ana M Linares, Heather M Wasser, Kaumudi J Joshipura, Cristina Palacios, Claudio Maffeis, Amanda L Thompson, Ata Ghaderi, Rajalakshmi Lakshman, Jinan C Banna, Emily Oken, Maribel Campos Rivera, Ana B Pérez-Expósito, Barry J Taylor, Jennifer S Savage, Margrethe Røed, Michael Goran, Kayla de la Haye, Stephanie Anzman-Frasca, Anna Lene Seidler, Transforming Obesity Prevention for CHILDren (TOPCHILD) Collaboration
Feb 21, 2022
INTRODUCTION: Little is known about how early (eg, commencing antenatally or in the first 12 months after birth) obesity prevention interventions seek to change behaviour and which components are or are not effective. This study...
Transforming Obesity Prevention for CHILDren (TOPCHILD) Collaboration
Kylie E Hunter, Brittany J Johnson, Lisa Askie, Rebecca K Golley, Louise A Baur, Ian C Marschner, Rachael W Taylor, Luke Wolfenden, Charles T Wood, Seema Mihrshahi, Alison J Hayes, Chris Rissel, Kristy P Robledo, Denise A O'Connor, David Espinoza, Lukas P Staub, Paul Chadwick, Sarah Taki, Angie Barba, Sol Libesman, Mason Aberoumand, Wendy A Smith, Michelle Sue-See, Kylie D Hesketh, Jessica L Thomson, Maria Bryant, Ian M Paul, Vera Verbestel, Cathleen Odar Stough, Li Ming Wen, Junilla K Larsen, Sharleen L O'Reilly, Heather M Wasser, Jennifer S Savage, Ken K Ong, Sarah-Jeanne Salvy, Mary Jo Messito, Rachel S Gross, Levie T Karssen, Finn E Rasmussen, Karen Campbell, Ana Maria Linares, Nina Cecilie Øverby, Cristina Palacios, Kaumudi J Joshipura, Carolina González Acero, Rajalakshmi Lakshman, Amanda L Thompson, Claudio Maffeis, Emily Oken, Ata Ghaderi, Maribel Campos Rivera, Ana B Pérez-Expósito, Jinan C Banna, Kayla de la Haye, Michael Goran, Margrethe Røed, Stephanie Anzman-Frasca, Barry J Taylor, Anna Lene Seidler, Transforming Obesity Prevention for CHILDren (TOPCHILD) Collaboration
Feb 21, 2022
INTRODUCTION: Behavioural interventions in early life appear to show some effect in reducing childhood overweight and obesity. However, uncertainty remains regarding their overall effectiveness, and whether effectiveness differs...
Germline polymorphisms in an enhancer of PSIP1 are associated with progression-free survival in epithelial ovarian cancer.
Juliet D French, Sharon E Johnatty, Yi Lu, Jonathan Beesley, Bo Gao, Murugan Kalimutho, Michelle J Henderson, Amanda J Russell, Siddhartha Kar, Xiaoqing Chen, Kristine M Hillman, Susanne Kaufmann, Haran Sivakumaran, Martin O'Reilly, Chen Wang, Darren J Korbie, Australian Ovarian Cancer Study Group, Australian Ovarian Cancer Study, Diether Lambrechts, Evelyn Despierre, Els Van Nieuwenhuysen, Sandrina Lambrechts, Ignace Vergote, Beth Karlan, Jenny Lester, Sandra Orsulic, Christine Walsh, Peter A Fasching, Matthias W Beckmann, Arif B Ekici, Alexander Hein, Keitaro Matsuo, Satoyo Hosono, Jacobus Pisterer, Peter Hillemanns, Toru Nakanishi, Yasushi Yatabe, Marc T Goodman, Galina Lurie, Rayna K Matsuno, Pamela J Thompson, Tanja Pejovic, Yukie Bean, Florian Heitz, Philipp Harter, Andreas du Bois, Ira Schwaab, Estrid Hogdall, Susanne K Kjaer, Allan Jensen, Claus Hogdall, Lene Lundvall, Svend Aage Engelholm, Bob Brown, James M Flanagan, Michelle D Metcalf, Nadeem Siddiqui, Thomas Sellers, Brooke Fridley, Julie Cunningham, Joellen M Schildkraut, Ed Iversen, Rachel Palmieri Weber, Donal Brennan, Andrew Berchuck, Paul Pharoah, Paul Harnett, Murray D Norris, Michelle Haber, Ellen L Goode, Jason S Lee, Kum Kum Khanna, Kerstin B Meyer, Georgia Chenevix-Trench, Anna DeFazio, Stacey L Edwards, Stuart MacGregor, Ovarian Cancer Association Consortium
Mar 16, 2016
PSIP1 chromosome conformation capture epithelial ovarian cancer Genome-Wide Association Study progression free survival Adaptor Proteins Signal Transducing Apoptosis Biomarkers Tumor Cell Proliferation Chromatin Immunoprecipitation Cohort Studies Cystadenocarcinoma Serous Electrophoretic Mobility Shift Assay Enhancer Elements Genetic Fallopian Tube Neoplasms Female Follow-Up Studies Germ-Line Mutation Humans Ovarian Neoplasms Peritoneal Neoplasms Polymorphism Single Nucleotide Prognosis RNA Messenger Real-Time Polymerase Chain Reaction Reverse Transcriptase Polymerase Chain Reaction Survival Rate Transcription Factors Tumor Cells Cultured
Unpacking the behavioural components and delivery features of early childhood obesity prevention interventions in the TOPCHILD Collaboration
Brittany J Johnson, Kylie E Hunter, Rebecca K Golley, Paul Chadwick, Angie Barba, Mason Aberoumand, Sol Libesman, Lisa Askie, Rachael W Taylor, Kristy P Robledo, Seema Mihrshahi, Denise A O'Connor, Alison J Hayes, Luke Wolfenden, Charles T Wood, Louise A Baur, Chris Rissel, Lukas P Staub, Sarah Taki, Wendy Smith, Michelle Sue-See, Ian C Marschner, David Espinoza, Jessica L Thomson, Junilla K Larsen, Vera Verbestel, Cathleen Odar Stough, Sarah-Jeanne Salvy, Sharleen L O'Reilly, Levie T Karssen, Finn E Rasmussen, Mary Jo Messito, Rachel S Gross, Maria Bryant, Ian M Paul, Li Ming Wen, Kylie D Hesketh, Carolina González Acero, Karen Campbell, Nina Cecilie Øverby, Ana M Linares, Heather M Wasser, Kaumudi J Joshipura, Cristina Palacios, Claudio Maffeis, Amanda L Thompson, Ata Ghaderi, Rajalakshmi Lakshman, Jinan C Banna, Emily Oken, Maribel Campos Rivera, Ana B Pérez-Expósito, Barry J Taylor, Jennifer S Savage, Margrethe Røed, Michael Goran, Kayla de la Haye, Stephanie Anzman-Frasca, Anna Lene Seidler, Transforming Obesity Prevention for CHILDren (TOPCHILD) Collaboration
Jan 28, 2022
INTRODUCTION: Little is known about how early (eg, commencing antenatally or in the first 12 months after birth) obesity prevention interventions seek to change behaviour and which components are or are not effective. This study...
Transforming Obesity Prevention for CHILDren (TOPCHILD) Collaboration
Kylie E Hunter, Brittany J Johnson, Lisa Askie, Rebecca K Golley, Louise A Baur, Ian C Marschner, Rachael W Taylor, Luke Wolfenden, Charles T Wood, Seema Mihrshahi, Alison J Hayes, Chris Rissel, Kristy P Robledo, Denise A O'Connor, David Espinoza, Lukas P Staub, Paul Chadwick, Sarah Taki, Angie Barba, Sol Libesman, Mason Aberoumand, Wendy A Smith, Michelle Sue-See, Kylie D Hesketh, Jessica L Thomson, Maria Bryant, Ian M Paul, Vera Verbestel, Cathleen Odar Stough, Li Ming Wen, Junilla K Larsen, Sharleen L O'Reilly, Heather M Wasser, Jennifer S Savage, Kenneth Ong, Sarah-Jeanne Salvy, Mary Jo Messito, Rachel S Gross, Levie T Karssen, Finn E Rasmussen, Karen Campbell, Ana Maria Linares, Nina Cecilie Øverby, Cristina Palacios, Kaumudi J Joshipura, Carolina González Acero, Rajalakshmi Lakshman, Amanda L Thompson, Claudio Maffeis, Emily Oken, Ata Ghaderi, Maribel Campos Rivera, Ana B Pérez-Expósito, Jinan C Banna, Kayla de la Haye, Michael Goran, Margrethe Røed, Stephanie Anzman-Frasca, Barry J Taylor, Anna Lene Seidler, Transforming Obesity Prevention for CHILDren (TOPCHILD) Collaboration
Jan 28, 2022
INTRODUCTION: Behavioural interventions in early life appear to show some effect in reducing childhood overweight and obesity. However, uncertainty remains regarding their overall effectiveness, and whether effectiveness differs...
Clinical and pathological associations of PTEN expression in ovarian cancer
Filipe Correia Martins, Dominique-Laurent Couturier, Anna Paterson, Anthony N. Karnezis, Christine Chow, Tayyebeh M. Nazeran, Adekunle Odunsi, Aleksandra Gentry-Maharaj, Aleksandra Vrvilo, Alexander Hein, Aline Talhouk, Ana Osorio, Andreas D. Hartkopf, Angela Brooks-Wilson, Anna DeFazio, Anna Fischer, Arndt Hartmann, Brenda Y. Hernandez, Bryan M. McCauley, Chloe Karpinskyj, Christiani B. de Sousa, Claus Høgdall, Daniel G. Tiezzi, Esther Herpel, Florin Andrei Taran, Francesmary Modugno, Gary Keeney, Gregg Nelson, Helen Steed, Honglin Song, Hugh Luk, Javier Benitez, Jennifer Alsop, Jennifer M. Koziak, Jenny Lester, Joseph H. Rothstein, Jurandyr M. de Andrade, Lene Lundvall, Luis Paz-Ares, Luis Robles-Díaz, Lynne R. Wilkens, Maria J. Garcia, Maria P. Intermaggio, Marie-Lyne Alcaraz, Mary A. Brett, Matthias W. Beckmann, Mercedes Jimenez-Linan, Michael Anglesio, Michael E. Carney, Michael Schneider, Nadia Traficante, Nadja Pejovic, Naveena Singh, Nhu Le, Peter Sinn, Prafull Ghatage, Ramona Erber, Robert Edwards, Robert Vierkant, Roberta B. Ness, Samuel Leung, Sandra Orsulic, Sara Y. Brucker, Scott H. Kaufmann, Sian Fereday, Simon Gayther, Stacey J. Winham, Stefan Kommoss, Tanja Pejovic, Teri A. Longacre, Valerie McGuire, Valerie Rhenius, Weiva Sieh, Yurii B. Shvetsov, Alice S. Whittemore, Annette Staebler, Beth Y. Karlan, Cristina Rodriguez-Antona, David D. Bowtell, Ellen L. Goode, Estrid Høgdall, Francisco J. Candido dos Reis, Jacek Gronwald, Jenny Chang-Claude, Kirsten B. Moysich, Linda E. Kelemen, Linda S. Cook, Marc T. Goodman, Peter A. Fasching, Robin Crawford, Suha Deen, Usha Menon, David G. Huntsman, Martin Köbel, Susan J. Ramus, Paul D. P. Pharoah, James D. Brenton
Sep 01, 2020
Abstract: Background: PTEN loss is a putative driver in histotypes of ovarian cancer (high-grade serous (HGSOC), endometrioid (ENOC), clear cell (CCOC), mucinous (MOC), low-grade serous (LGSOC)). We aimed to characterise PTEN...
Clinical and pathological associations of PTEN expression in ovarian cancer
Filipe Correia Martins, Dominique-Laurent Couturier, Anna Paterson, Anthony N Karnezis, Christine Chow, Tayyebeh M Nazeran, Adekunle Odunsi, Aleksandra Gentry-Maharaj, Aleksandra Vrvilo, Alexander Hein, Aline Talhouk, Ana Osorio, Andreas D Hartkopf, Angela Brooks-Wilson, Anna DeFazio, Anna Fischer, Arndt Hartmann, Brenda Y Hernandez, Bryan M McCauley, Chloe Karpinskyj, Christiani B de Sousa, Claus Høgdall, Daniel G Tiezzi, Esther Herpel, Florin Andrei Taran, Francesmary Modugno, Gary Keeney, Gregg Nelson, Helen Steed, Honglin Song, Hugh Luk, Javier Benitez, Jennifer Alsop, Jennifer M Koziak, Jenny Lester, Joseph H Rothstein, Jurandyr M de Andrade, Lene Lundvall, Luis Paz-Ares, Luis Robles-Díaz, Lynne R Wilkens, Maria J Garcia, Maria P Intermaggio, Marie-Lyne Alcaraz, Mary A Brett, Matthias W Beckmann, Mercedes Jimenez-Linan, Michael Anglesio, Michael E Carney, Michael Schneider, Nadia Traficante, Nadja Pejovic, Naveena Singh, Nhu Le, Peter Sinn, Prafull Ghatage, Ramona Erber, Robert Edwards, Robert Vierkant, Roberta B Ness, Samuel Leung, Sandra Orsulic, Sara Y Brucker, Scott H Kaufmann, Sian Fereday, Simon Gayther, Stacey J Winham, Stefan Kommoss, Tanja Pejovic, Teri A Longacre, Valerie McGuire, Valerie Rhenius, Weiva Sieh, Yurii B Shvetsov, Alice S Whittemore, Annette Staebler, Beth Y Karlan, Cristina Rodriguez-Antona, David D Bowtell, Ellen L Goode, Estrid Høgdall, Francisco J Candido Dos Reis, Jacek Gronwald, Jenny Chang-Claude, Kirsten B Moysich, Linda E Kelemen, Linda S Cook, Marc T Goodman, Peter A Fasching, Robin Crawford, Suha Deen, Usha Menon, David G Huntsman, Martin Köbel, Susan J Ramus, Paul DP Pharoah, James D Brenton
Mar 06, 2020
BACKGROUND: PTEN loss is a putative driver in histotypes of ovarian cancer (high-grade serous (HGSOC), endometrioid (ENOC), clear cell (CCOC), mucinous (MOC), low-grade serous (LGSOC)). We aimed to characterise PTEN expression...
Adenocarcinoma Clear Cell Age Factors Biomarkers Tumor Carcinoma Ovarian Epithelial Cohort Studies Down-Regulation Female Gene Knockout Techniques Humans Middle Aged Neoplasm Staging Ovarian Neoplasms PTEN Phosphohydrolase Prospective Studies Receptors Androgen Receptors Estrogen Receptors Progesterone Tissue Array Analysis Tumor Suppressor Proteins
Clinical and pathological associations of PTEN expression in ovarian cancer
Filipe Correia Martins, Dominique-Laurent Couturier, Anna Paterson, Anthony N. Karnezis, Christine Chow, Tayyebeh M. Nazeran, Adekunle Odunsi, Aleksandra Gentry-Maharaj, Aleksandra Vrvilo, Alexander Hein, Aline Talhouk, Ana Osorio, Andreas D. Hartkopf, Angela Brooks-Wilson, Anna DeFazio, Anna Fischer, Arndt Hartmann, Brenda Y. Hernandez, Bryan M. McCauley, Chloe Karpinskyj, Christiani B. de Sousa, Claus Høgdall, Daniel G. Tiezzi, Esther Herpel, Florin Andrei Taran, Francesmary Modugno, Gary Keeney, Gregg Nelson, Helen Steed, Honglin Song, Hugh Luk, Javier Benitez, Jennifer Alsop, Jennifer M. Koziak, Jenny Lester, Joseph H. Rothstein, Jurandyr M. de Andrade, Lene Lundvall, Luis Paz-Ares, Luis Robles-Díaz, Lynne R. Wilkens, Maria J. Garcia, Maria P. Intermaggio, Marie-Lyne Alcaraz, Mary A. Brett, Matthias W. Beckmann, Mercedes Jimenez-Linan, Michael Anglesio, Michael E. Carney, Michael Schneider, Nadia Traficante, Nadja Pejovic, Naveena Singh, Nhu Le, Peter Sinn, Prafull Ghatage, Ramona Erber, Robert Edwards, Robert Vierkant, Roberta B. Ness, Samuel Leung, Sandra Orsulic, Sara Y. Brucker, Scott H. Kaufmann, Sian Fereday, Simon Gayther, Stacey J. Winham, Stefan Kommoss, Tanja Pejovic, Teri A. Longacre, Valerie McGuire, Valerie Rhenius, Weiva Sieh, Yurii B. Shvetsov, Alice S. Whittemore, Annette Staebler, Beth Y. Karlan, Cristina Rodriguez-Antona, David D. Bowtell, Ellen L. Goode, Estrid Høgdall, Francisco J. Candido dos Reis, Jacek Gronwald, Jenny Chang-Claude, Kirsten B. Moysich, Linda E. Kelemen, Linda S. Cook, Marc T. Goodman, Peter A. Fasching, Robin Crawford, Suha Deen, Usha Menon, David G. Huntsman, Martin Köbel, Susan J. Ramus, Paul D. P. Pharoah, James D. Brenton
Jun 18, 2021
Abstract: Background: PTEN loss is a putative driver in histotypes of ovarian cancer (high-grade serous (HGSOC), endometrioid (ENOC), clear cell (CCOC), mucinous (MOC), low-grade serous (LGSOC)). We aimed to characterise PTEN...
Variants in genes encoding small GTPases and association with epithelial ovarian cancer susceptibility.
Madalene Earp, Jonathan P Tyrer, Stacey J Winham, Hui-Yi Lin, Ganna Chornokur, Joe Dennis, Katja KH Aben, Hoda Anton-Culver, Natalia Antonenkova, Elisa V Bandera, Yukie T Bean, Matthias W Beckmann, Line Bjorge, Natalia Bogdanova, Louise A Brinton, Angela Brooks-Wilson, Fiona Bruinsma, Clareann H Bunker, Ralf Butzow, Ian G Campbell, Karen Carty, Jenny Chang-Claude, Linda S Cook, Daniel W Cramer, Julie M Cunningham, Cezary Cybulski, Agnieszka Dansonka-Mieszkowska, Evelyn Despierre, Jennifer A Doherty, Thilo Dörk, Andreas du Bois, Matthias Dürst, Douglas F Easton, Diana M Eccles, Robert P Edwards, Arif B Ekici, Peter A Fasching, Brooke L Fridley, Aleksandra Gentry-Maharaj, Graham G Giles, Rosalind Glasspool, Marc T Goodman, Jacek Gronwald, Philipp Harter, Alexander Hein, Florian Heitz, Michelle AT Hildebrandt, Peter Hillemanns, Claus K Hogdall, Estrid Høgdall, Satoyo Hosono, Edwin S Iversen, Anna Jakubowska, Allan Jensen, Bu-Tian Ji, Audrey Y Jung, Beth Y Karlan, Melissa Kellar, Lambertus A Kiemeney, Boon Kiong Lim, Susanne K Kjaer, Camilla Krakstad, Jolanta Kupryjanczyk, Diether Lambrechts, Sandrina Lambrechts, Nhu D Le, Shashi Lele, Jenny Lester, Douglas A Levine, Zheng Li, Dong Liang, Jolanta Lissowska, Karen Lu, Jan Lubinski, Lene Lundvall, Leon FAG Massuger, Keitaro Matsuo, Valerie McGuire, John R McLaughlin, Iain McNeish, Usha Menon, Roger L Milne, Francesmary Modugno, Kirsten B Moysich, Roberta B Ness, Heli Nevanlinna, Kunle Odunsi, Sara H Olson, Irene Orlow, Sandra Orsulic, James Paul, Tanja Pejovic, Liisa M Pelttari, Jenny B Permuth, Malcolm C Pike, Elizabeth M Poole, Barry Rosen, Mary Anne Rossing, Joseph H Rothstein, Ingo B Runnebaum, Iwona K Rzepecka, Eva Schernhammer, Ira Schwaab, Xiao-Ou Shu, Yurii B Shvetsov, Nadeem Siddiqui, Weiva Sieh, Honglin Song, Melissa C Southey, Beata Spiewankiewicz, Lara Sucheston-Campbell, Ingvild L Tangen, Soo-Hwang Teo, Kathryn L Terry, Pamela J Thompson, Lotte Thomsen, Shelley S Tworoger, Anne M van Altena, Ignace Vergote, Liv Cecilie Vestrheim Thomsen, Robert A Vierkant, Christine S Walsh, Shan Wang-Gohrke, Nicolas Wentzensen, Alice S Whittemore, Kristine G Wicklund, Lynne R Wilkens, Yin-Ling Woo, Anna H Wu, Xifeng Wu, Yong-Bing Xiang, Hannah Yang, Wei Zheng, Argyrios Ziogas, Alice W Lee, Celeste L Pearce, Andrew Berchuck, Joellen M Schildkraut, Susan J Ramus, Alvaro NA Monteiro, Steven A Narod, Thomas A Sellers, Simon A Gayther, Linda E Kelemen, Georgia Chenevix-Trench, Harvey A Risch, Paul DP Pharoah, Ellen L Goode, Catherine M Phelan
Sep 05, 2018
Epithelial ovarian cancer (EOC) is the fifth leading cause of cancer mortality in American women. Normal ovarian physiology is intricately connected to small GTP binding proteins of the Ras superfamily (Ras, Rho, Rab, Arf, and...
Assessment of variation in immunosuppressive pathway genes reveals TGFBR2 to be associated with risk of clear cell ovarian cancer.
Shalaka S Hampras, Lara E Sucheston-Campbell, Rikki Cannioto, Jenny Chang-Claude, Francesmary Modugno, Thilo Dörk, Peter Hillemanns, Leah Preus, Keith L Knutson, Paul K Wallace, Chi-Chen Hong, Grace Friel, Warren Davis, Mary Nesline, Celeste L Pearce, Linda E Kelemen, Marc T Goodman, Elisa V Bandera, Kathryn L Terry, Nils Schoof, Kevin H Eng, Alyssa Clay, Prashant K Singh, Janine M Joseph, Katja KH Aben, Hoda Anton-Culver, Natalia Antonenkova, Helen Baker, Yukie Bean, Matthias W Beckmann, Maria Bisogna, Line Bjorge, Natalia Bogdanova, Louise A Brinton, Angela Brooks-Wilson, Fiona Bruinsma, Ralf Butzow, Ian G Campbell, Karen Carty, Linda S Cook, Daniel W Cramer, Cezary Cybulski, Agnieszka Dansonka-Mieszkowska, Joe Dennis, Evelyn Despierre, Ed Dicks, Jennifer A Doherty, Andreas du Bois, Matthias Dürst, Doug Easton, Diana Eccles, Robert P Edwards, Arif B Ekici, Peter A Fasching, Brooke L Fridley, Yu-Tang Gao, Aleksandra Gentry-Maharaj, Graham G Giles, Rosalind Glasspool, Jacek Gronwald, Patricia Harrington, Philipp Harter, Hanis Nazihah Hasmad, Alexander Hein, Florian Heitz, Michelle AT Hildebrandt, Claus Hogdall, Estrid Hogdall, Satoyo Hosono, Edwin S Iversen, Anna Jakubowska, Allan Jensen, Bu-Tian Ji, Beth Y Karlan, Melissa Kellar, Joseph L Kelley, Lambertus A Kiemeney, Rüdiger Klapdor, Nonna Kolomeyevskaya, Camilla Krakstad, Susanne K Kjaer, Bridget Kruszka, Jolanta Kupryjanczyk, Diether Lambrechts, Sandrina Lambrechts, Nhu D Le, Alice W Lee, Shashikant Lele, Arto Leminen, Jenny Lester, Douglas A Levine, Dong Liang, Jolanta Lissowska, Song Liu, Karen Lu, Jan Lubinski, Lene Lundvall, Leon FAG Massuger, Keitaro Matsuo, Valeria McGuire, John R McLaughlin, Ian McNeish, Usha Menon, Joanna Moes-Sosnowska, Steven A Narod, Lotte Nedergaard, Heli Nevanlinna, Stefan Nickels, Sara H Olson, Irene Orlow, Rachel Palmieri Weber, James Paul, Tanja Pejovic, Liisa M Pelttari, Barbara Perkins, Jenny Permuth-Wey, Malcolm C Pike, Joanna Plisiecka-Halasa, Elizabeth M Poole, Harvey A Risch, Mary Anne Rossing, Joseph H Rothstein, Anja Rudolph, Ingo B Runnebaum, Iwona K Rzepecka, Helga B Salvesen, Eva Schernhammer, Kristina Schmitt, Ira Schwaab, Xiao-Ou Shu, Yurii B Shvetsov, Nadeem Siddiqui, Weiva Sieh, Honglin Song, Melissa C Southey, Ingvild L Tangen, Soo-Hwang Teo, Pamela J Thompson, Agnieszka Timorek, Ya-Yu Tsai, Shelley S Tworoger, Jonathan Tyrer, Anna M van Altena, Ignace Vergote, Robert A Vierkant, Christine Walsh, Shan Wang-Gohrke, Nicolas Wentzensen, Alice S Whittemore, Kristine G Wicklund, Lynne R Wilkens, Anna H Wu, Xifeng Wu, Yin-Ling Woo, Hannah Yang, Wei Zheng, Argyrios Ziogas, Simon A Gayther, Susan J Ramus, Thomas A Sellers, Joellen M Schildkraut, Catherine M Phelan, Andrew Berchuck, Georgia Chenevix-Trench, Julie M Cunningham, Paul P Pharoah, Roberta B Ness, Kunle Odunsi, Ellen L Goode, Kirsten B Moysich
Nov 23, 2018
BACKGROUND: Regulatory T (Treg) cells, a subset of CD4+ T lymphocytes, are mediators of immunosuppression in cancer, and, thus, variants in genes encoding Treg cell immune molecules could be associated with ovarian cancer....
TGFBR2 Biomarkers genetic variation immunosuppression ovarian cancer Adenocarcinoma Clear Cell Adult Aged Female Gene Expression Regulation Neoplastic Gene Frequency Genetic Predisposition to Disease Genotype Humans Middle Aged Neoplasms Glandular and Epithelial Ovarian Neoplasms Polymorphism Single Nucleotide Protein-Serine-Threonine Kinases Receptors Transforming Growth Factor beta Risk Factors T-Lymphocytes Regulatory
Adult height is associated with increased risk of ovarian cancer
Suzanne C Dixon-Suen, Christina M Nagle, Aaron P Thrift, Paul DP Pharoah, Ailith Ewing, Celeste Leigh Pearce, Wei Zheng, Australian Ovarian Cancer Study Group, Georgia Chenevix-Trench, Peter A Fasching, Matthias W Beckmann, Diether Lambrechts, Ignace Vergote, Sandrina Lambrechts, Els Van Nieuwenhuysen, Mary Anne Rossing, Jennifer A Doherty, Kristine G Wicklund, Jenny Chang-Claude, Audrey Y Jung, Kirsten B Moysich, Kunle Odunsi, Marc T Goodman, Lynne R Wilkens, Pamela J Thompson, Yurii B Shvetsov, Thilo Dörk, Tjoung-Won Park-Simon, Peter Hillemanns, Natalia Bogdanova, Ralf Butzow, Heli Nevanlinna, Liisa M Pelttari, Arto Leminen, Francesmary Modugno, Roberta B Ness, Robert P Edwards, Joseph L Kelley, Florian Heitz, Andreas du Bois, Philipp Harter, Ira Schwaab, Beth Y Karlan, Jenny Lester, Sandra Orsulic, Bobbie J Rimel, Susanne K Kjaer, Estrid Høgdall, Allan Jensen, Ellen L Goode, Brooke L Fridley, Julie M Cunningham, Stacey J Winham, Graham G Giles, Fiona Bruinsma, Roger L Milne, Melissa C Southey, Michelle AT Hildebrandt, Xifeng Wu, Karen H Lu, Dong Liang, Douglas A Levine, Maria Bisogna, Joellen M Schildkraut, Andrew Berchuck, Daniel W Cramer, Kathryn L Terry, Elisa V Bandera, Sara H Olson, Helga B Salvesen, Liv Cecilie Vestrheim Thomsen, Reidun K Kopperud, Line Bjorge, Lambertus A Kiemeney, Leon FAG Massuger, Tanja Pejovic, Amanda Bruegl, Linda S Cook, Nhu D Le, Kenneth D Swenerton, Angela Brooks-Wilson, Linda E Kelemen, Jan Lubiński, Tomasz Huzarski, Jacek Gronwald, Janusz Menkiszak, Nicolas Wentzensen, Louise Brinton, Hannah Yang, Jolanta Lissowska, Claus K Høgdall, Lene Lundvall, Honglin Song, Jonathan P Tyrer, Ian Campbell, Diana Eccles, James Paul, Rosalind Glasspool, Nadeem Siddiqui, Alice S Whittemore, Weiva Sieh, Valerie McGuire, Joseph H Rothstein, Steven A Narod, Catherine Phelan, Harvey A Risch, John R McLaughlin, Hoda Anton-Culver, Argyrios Ziogas, Usha Menon, Simon A Gayther, Susan J Ramus, Aleksandra Gentry-Maharaj, Anna H Wu, Malcolm C Pike, Chiu-Chen Tseng, Jolanta Kupryjanczyk, Agnieszka Dansonka-Mieszkowska, Agnieszka Budzilowska, Iwona K Rzepecka, Penelope M Webb, Ovarian Cancer Association Consortium
May 23, 2018
BACKGROUND: Observational studies suggest greater height is associated with increased ovarian cancer risk, but cannot exclude bias and/or confounding as explanations for this. Mendelian randomisation (MR) can provide evidence...
|
|< |
< |
1 |