Search
Results: 296
Giovanni Canestrini’s models of Leonardo da Vinci’s friction experiments
IM Hutchings
Feb 16, 2017
Among the exhibits at the 2016 Leonardo da Vinci exhibition at the Science Museum, London, was one that purported to illustrate Leonardo’s experiments on friction. The models involved were the work of Giovanni Canestrini...
Dual mode imaging in mid infrared with thermal signal reconstruction for innovative diagnostics of the "Monocromo" by Leonardo da Vinci.
Dual mode imaging in the mid infrared band, a joint use of thermography and quasi-thermal reflectography, was recently proposed as a full field diagnostic tool in cultural heritage. Here we discuss for the first time, to the...
Protein structural transitions critically transform the network connectivity and viscoelasticity of RNA-binding protein condensates but RNA can prevent it.
Mind the Gap
The way organelles are viewed by cell biologists is quickly changing. For many years, these cellular entities were thought to be unique and singular structures that performed specific roles. However, in recent decades...
Brochemical Studies of Peptidoglycan Hydrolases from Commensal and Pathogenic Bacteria
Juliel Espinosa
Jan 01, 0001
The intestinal microbiota consists of diverse bacterial species and their effectors that play key roles in regulating human health. Interestingly, cell wall, or peptidoglycan, fragments from commensal and pathogenic bacteria can...
Published by: Rockefeller University
Alzheimer’s and Parkinson’s Diseases Predict Different COVID-19 Outcomes
In December 2019, a coronavirus, severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), began infecting humans, causing a novel disease, coronavirus disease 19 (COVID-19). This was first described in the Wuhan province of...
Links between air pollution and COVID-19 in England.
Marco Travaglio, Yizhou Yu, Rebeka Popovic, Liza Selley, Nuno Santos Leal, Luis Miguel Martins
Feb 26, 2021
In December 2019, a novel disease, coronavirus disease 19 (COVID-19), emerged in Wuhan, People's Republic of China. COVID-19 is caused by a novel coronavirus (SARS-CoV-2) presumed to have jumped species from another mammal to...
Protein structural transitions critically transform the network connectivity and viscoelasticity of RNA-binding protein condensates but RNA can prevent it.
Android-IoT Malware Classification and Detection Approach Using Deep URL Features Analysis
Currently, malware attacks pose a high risk to compromise the security of Android-IoT apps. These threats have the potential to steal critical information, causing economic, social, and financial harm. Because of their constant...
Published by: IGI Global Scientific Publishing
Evolution of protein complexes by duplication of homomeric interactions.
BACKGROUND: Cellular functions are accomplished by the concerted actions of functional modules. The mechanisms driving the emergence and evolution of these modules are still unclear. Here we investigate the evolutionary origins...
3D complex
Most of the proteins in a cell assemble into complexes to carry out their function. It is therefore crucial to understand the physicochemical properties as well as the evolution of interactions between proteins. The Protein Data...
MRSA carrying mecC in captive mara.
WGS methicillin resistance wildlife zoo Animals Animals Zoo Anti-Bacterial Agents DNA Bacterial Denmark Genes Bacterial Genome Bacterial Methicillin-Resistant Staphylococcus aureus Microbial Sensitivity Tests Polymerase Chain Reaction Rodentia Sequence Analysis DNA Staphylococcal Infections Virulence Factors
Management Support Model for Information Technology Outsourcing
This study deals with the problem of outsourcing management, presenting a structure to support decision-making on effective information-technology outsourcing and highlighting the advantages and disadvantages that must be...
Published by: IGI Global Scientific Publishing
Integrated view of Vibrio cholerae in the Americas.
Daryl Domman, Marie-Laure Quilici, Matthew J Dorman, Elisabeth Njamkepo, Ankur Mutreja, Alison E Mather, Gabriella Delgado, Rosario Morales-Espinosa, Patrick AD Grimont, Marcial Leonardo Lizárraga-Partida, Christiane Bouchier, David M Aanensen, Pablo Kuri-Morales, Cheryl L Tarr, Gordon Dougan, Julian Parkhill, Josefina Campos, Alejandro Cravioto, François-Xavier Weill, Nicholas R Thomson
Feb 15, 2019
Latin America has experienced two of the largest cholera epidemics in modern history; one in 1991 and the other in 2010. However, confusion still surrounds the relationships between globally circulating pandemic Vibrio cholerae...
Leonardo da Vinci's studies of friction
IM Hutchings
Apr 28, 2016
Expansion of Intrinsically Disordered Proteins Increases the Range of Stability of Liquid–Liquid Phase Separation
Proteins containing intrinsically disordered regions (IDRs) are ubiquitous within biomolecular condensates, which are liquid-like compartments within cells formed through liquid−liquid phase separation (LLPS). The sequence of...
Kinetic interplay between droplet maturation and coalescence modulates shape of aged protein condensates.
Biomolecular condensates formed by the process of liquid-liquid phase separation (LLPS) play diverse roles inside cells, from spatiotemporal compartmentalisation to speeding up chemical reactions. Upon maturation, the...
Paracetamol Is Associated with a Lower Risk of COVID-19 Infection and Decreased ACE2 Protein Expression
Ibuprofen is a common over-the-counter drug taken for pain relief. However, recent studies have raised concerns about its potential toxic effect with coronavirus disease 2019 (COVID-19), which is caused by severe acute...
Valency and Binding Affinity Variations Can Regulate the Multilayered Organization of Protein Condensates with Many Components
Ignacio Sanchez-Burgos, Jorge R. Espinosa, Jerelle A. Joseph, Rosana Collepardo-Guevara
Feb 15, 2021
Biomolecular condensates, which assemble via the process of liquid–liquid phase separation (LLPS), are multicomponent compartments found ubiquitously inside cells. Experiments and simulations have shown that biomolecular...
Distinct responses of human peripheral blood cells to different misfolded protein oligomers.
Magdalena Leal-Lasarte, Benedetta Mannini, Fabrizio Chiti, Michele Vendruscolo, Christopher M Dobson, Cintia Roodveldt, David Pozo
Jun 21, 2021
Th1/Th17 Tregs Immunoregulation neurodegeneration peripheral immunity protein misfolding diseases Adult CD4-Positive T-Lymphocytes Cell Differentiation Cells Cultured Cytokines Humans Leukocytes Mononuclear Lymphocyte Activation Middle Aged Protein Folding Proteostasis Deficiencies T-Lymphocytes Regulatory Th1 Cells Th17 Cells
Role of Salt, Pressure, and Water Activity on Homogeneous Ice Nucleation.
Jorge R Espinosa, Guiomar D Soria, Jorge Ramirez, Chantal Valeriani, Carlos Vega, Eduardo Sanz
Dec 19, 2019
Pure water can be substantially supercooled below the melting temperature without transforming into ice. The achievable supercooling can be enhanced by adding solutes or by applying hydrostatic pressure. Avoiding ice formation...
Published by: J Phys Chem Lett
Valency and Binding Affinity Variations Can Regulate the Multilayered Organization of Protein Condensates with Many Components.
|
|< |
< |
1 |