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The Case Against Smooth Null Infinity III
Abstract In this paper, we derive the early-time asymptotics for fixed-frequency solutions $$\phi _\ell $$
Leonhard MA Kehrberger
Jun 07, 2022
The promise of two-person neuroscience for developmental psychiatry
UNLABELLED: Social interactions are fundamental for human development, and disordered social interactions are pervasive in many psychiatric disorders. Recent advances in 'two-person neuroscience' have provided new tools for...
On the relation between asymptotic charges, the failure of peeling and late-time tails
Abstract
The last few years have seen considerable mathematical progress concerning the asymptotic structure of gravitational radiation in dynamical, astrophysical spacetimes. In...
On the relation between asymptotic charges, the failure of peeling and late-time tails
Abstract: The last few years have seen considerable mathematical progress concerning the asymptotic structure of gravitational radiation in dynamical, astrophysical spacetimes. In this paper, we distil some of the key ideas from...
Paper peeling Asymptotic analysis gravitational radiation Black Holes wave equation late-time tails linearised gravity
Published by: IOP Publishing
The Case Against Smooth Null Infinity III
Leonhard M. A. Kehrberger
Dec 10, 2022
In this paper, we derive the early-time asymptotics for fixed-frequency solutions ϕℓ to the wave equation □gϕℓ=0 on a fixed Schwarzschild background (M>0) arising from the no incoming radiation condition on I- and polynomially...
Manuscript Price’s law Asymptotics Logarithmic Asymptotics Early-time asymptotics Scattering constructions Boundary value problem peeling
Published by: Springer International Publishing
Consensus nomenclature for dyneins and associated assembly factors.
Bryony Braschi, Heymut Omran, George B Witman, Gregory J Pazour, K Kevin Pfister, Elspeth A Bruford, Stephen M King
Feb 10, 2022
Dyneins are highly complex, multicomponent, microtubule-based molecular motors. These enzymes are responsible for numerous motile behaviors in cytoplasm, mediate retrograde intraflagellar transport (IFT), and power ciliary and...
Changes in the composition of cannabis from 2000-2017 in Denmark
Kristine Rømer Thomsen, Christian Lindholst, Birgitte Thylstrup, Sinikka Kvamme, Lotte Ask Reitzel, Martin Worm-Leonhard, Amir Englund, Tom P. Freeman, Morten Hesse
Aug 01, 2019
Globally, recent studies report increases in Δ-9-tetrahydrocannabinol (THC) concentration in seized samples of cannabis for human consumption. This is important, because use of cannabis with a high concentration of THC has...
Cannabis CBD Gas chromatography with flame ionization detector THC /dk/atira/pure/subjectarea/asjc/3000/3004 name=Pharmacology /dk/atira/pure/subjectarea/asjc/2700/2738 name=Psychiatry and Mental health /dk/atira/pure/subjectarea/asjc/2700/2736 name=Pharmacology (medical) /dk/atira/pure/sustainabledevelopmentgoals/good_health_and_well_being name=SDG 3 - Good Health and Well-being
Changes in the composition of cannabis from 2000-2017 in Denmark
Kristine Rømer Thomsen, Christian Lindholst, Birgitte Thylstrup, Sinikka Kvamme, Lotte Ask Reitzel, Martin Worm-Leonhard, Amir Englund, Tom P. Freeman, Morten Hesse
Aug 01, 2019
Globally, recent studies report increases in Δ-9-tetrahydrocannabinol (THC) concentration in seized samples of cannabis for human consumption. This is important, because use of cannabis with a high concentration of THC has...
Cannabis CBD Gas chromatography with flame ionization detector THC /dk/atira/pure/subjectarea/asjc/3000/3004 name=Pharmacology /dk/atira/pure/subjectarea/asjc/2700/2738 name=Psychiatry and Mental health /dk/atira/pure/subjectarea/asjc/2700/2736 name=Pharmacology (medical) /dk/atira/pure/sustainabledevelopmentgoals/good_health_and_well_being name=SDG 3 - Good Health and Well-being
Influence of a novel, versatile bifunctional chelator on theranostic properties of a minigastrin analogue.
Joachim Pfister, Dominik Summer, Christine Rangger, Milos Petrik, Elisabeth von Guggenberg, Paolo Minazzi, Giovanni B Giovenzana, Luigi Aloj, Clemens Decristoforo
Dec 18, 2018
BACKGROUND: 6-[Bis(carboxymethyl)amino]-1,4-bis(carboxymethyl)-6-methyl-1,4-diazepane (AAZTA ) is a promising chelator with potential advantages over 1,4,7,10-tetraazacyclododecane-1,4,7,10-tetraacetic acid (DOTA) for...
A pervasive role for biomass burning in tropical high ozone/low water structures.
Daniel C Anderson, Julie M Nicely, Ross J Salawitch, Timothy P Canty, Russell R Dickerson, Thomas F Hanisco, Glenn M Wolfe, Eric C Apel, Elliot Atlas, Thomas Bannan, Stephane Bauguitte, Nicola J Blake, James F Bresch, Teresa L Campos, Lucy J Carpenter, Mark D Cohen, Mathew Evans, Rafael P Fernandez, Brian H Kahn, Douglas E Kinnison, Samuel R Hall, Neil RP Harris, Rebecca S Hornbrook, Jean-Francois Lamarque, Michael Le Breton, James D Lee, Carl Percival, Leonhard Pfister, R Bradley Pierce, Daniel D Riemer, Alfonso Saiz-Lopez, Barbara JB Stunder, Anne M Thompson, Kirk Ullmann, Adam Vaughan, Andrew J Weinheimer
Mar 08, 2016
Body mass index and body fat distribution and new-onset atrial fibrillation
J Neefs, SM Boekholdt, K-T Khaw, R Luben, R Pfister, NJ Wareham, ER Meulendijks, P Sanders, JR de Groot
Sep 06, 2019
BACKGROUND AND AIM: Obesity is a recognized risk factor for new-onset atrial fibrillation (AF). The association between body fat distribution, which is measured by body mass index (BMI) and waist-hip ratio (WHR), its changes...
Real-time deformability cytometry reveals sequential contraction and expansion during neutrophil priming.
Kathleen R Bashant, Arlette Vassallo, Christoph Herold, Reinhard Berner, Leonhard Menschner, Julien Subburayalu, Mariana J Kaplan, Charlotte Summers, Jochen Guck, Edwin R Chilvers, Nicole Toepfner
Mar 11, 2019
It has become increasingly apparent that the biomechanical properties of neutrophils impact on their trafficking through the circulation and in particularly through the pulmonary capillary bed. The retention of polarized or...
Hidden fairy rings and males-Genetic patterns of natural Burgundy truffle (Tuber aestivum Vittad.) populations reveal new insights into its life cycle.
CS Kwok, YK Loke, AA Welch, RN Luben, MAH Lentjes, SM Boekholdt, R Pfister, MA Mamas, NJ Wareham, K-T Khaw, PK Myint
Jan 18, 2016
Leonhard Euler and Johann Bernoulli Solving Homogenous Higher Order Linear Differential Equations With Constant Coefficients
Adam E Parker
Jan 01, 0001
linear differential equation Curriculum and Instruction Educational Methods Higher Education Science and Mathematics Education
Published by: Ursinus College
Lipocalin 2 Protects from Inflammation and Tumorigenesis Associated with Gut Microbiota Alterations.
Alexander R Moschen, Romana R Gerner, Jun Wang, Victoria Klepsch, Timon E Adolph, Simon J Reider, Hubert Hackl, Alexandra Pfister, Johannes Schilling, Patrizia L Moser, Sarah L Kempster, Alexander Swidsinski, Dorothea Orth Höller, Günter Weiss, John F Baines, Arthur Kaser, Herbert Tilg
Aug 16, 2016
Detection of human disease conditions by single-cell morpho-rheological phenotyping of blood.
Nicole Toepfner, Christoph Herold, Oliver Otto, Philipp Rosendahl, Angela Jacobi, Martin Kräter, Julia Stächele, Leonhard Menschner, Maik Herbig, Laura Ciuffreda, Lisa Ranford-Cartwright, Michal Grzybek, Ünal Coskun, Elisabeth Reithuber, Geneviève Garriss, Peter Mellroth, Birgitta Henriques-Normark, Nicola Tregay, Meinolf Suttorp, Martin Bornhäuser, Edwin R Chilvers, Reinhard Berner, Jochen Guck
Jun 12, 2018
Blood is arguably the most important bodily fluid and its analysis provides crucial health status information. A first routine measure to narrow down diagnosis in clinical practice is the differential blood count, determining...
Artificial miRNAs Reduce Human Mutant Huntingtin Throughout the Striatum in a Transgenic Sheep Model of Huntington's Disease.
Edith L Pfister, Natalie DiNardo, Erica Mondo, Florie Borel, Faith Conroy, Cara Fraser, Gwladys Gernoux, Xin Han, Danjing Hu, Emily Johnson, Lori Kennington, PengPeng Liu, Suzanne J Reid, Ellen Sapp, Petr Vodicka, Tim Kuchel, A Jennifer Morton, David Howland, Richard Moser, Miguel Sena-Esteves, Guangping Gao, Christian Mueller, Marian DiFiglia, Neil Aronin
Sep 20, 2018
Huntington's disease (HD) is a fatal neurodegenerative disease caused by a genetic expansion of the CAG repeat region in the huntingtin (HTT) gene. Studies in HD mouse models have shown that artificial miRNAs can reduce mutant...
AAV Huntington's disease RNAi large animal models Animals Animals Genetically Modified Dependovirus Disease Models Animal Electrolytes Genetic Vectors Genome Viral Humans Huntingtin Protein Huntington Disease Immunoassay Injections Kidney Liver MicroRNAs Microglia Mutant Proteins Neostriatum Neurons RNA Messenger Sheep
Reply to 'Assembling the brain trust
Kenneth Aldape, Kevin M Brindle, Louis Chesler, Rajesh Chopra, Amar Gajjar, Mark R Gilbert, Nicholas Gottardo, David H Gutmann, Darren Hargrave, Eric C Holland, David TW Jones, Johanna A Joyce, Pamela Kearns, Mark W Kieran, Ingo K Mellinghoff, Melinda Merchant, Stefan M Pfister, Steven M Pollard, Vijay Ramaswamy, Jeremy N Rich, Giles W Robinson, David H Rowitch, John H Sampson, Michael D Taylor, Paul Workman, Richard J Gilbertson
Sep 27, 2019
Despite decades of research, brain tumours remain among the deadliest of all forms of cancer. The ability of these tumours to resist almost all conventional and novel treatments relates, in part, to the unique cell-intrinsic and...
Structured inquiry-based learning
Christopher R Dunne, Anthony R Cillo, Danielle R Glick, Katherine John, Cody Johnson, Jaspinder Kanwal, Brian T Malik, Kristina Mammano, Stefan Petrovic, William Pfister, Alexander S Rascoe, Diane Schrom, Scott Shapiro, Jeffrey W Simkins, David Strauss, Rene Talai, John P Tomtishen, Josephine Vargas, Tony Veloz, Thomas O Vogler, Michael E Clenshaw, Devin T Gordon-Hamm, Kathryn L Lee, Elizabeth C Marin
Jun 11, 2020
We have developed and tested two linked but separable structured inquiry exercises using a set of Drosophila melanogaster GAL4 enhancer trap strains for an upper-level undergraduate laboratory methods course at Bucknell...
Challenges to curing primary brain tumours.
Kenneth Aldape, Kevin M Brindle, Louis Chesler, Rajesh Chopra, Amar Gajjar, Mark R Gilbert, Nicholas Gottardo, David H Gutmann, Darren Hargrave, Eric C Holland, David TW Jones, Johanna A Joyce, Pamela Kearns, Mark W Kieran, Ingo K Mellinghoff, Melinda Merchant, Stefan M Pfister, Steven M Pollard, Vijay Ramaswamy, Jeremy N Rich, Giles W Robinson, David H Rowitch, John H Sampson, Michael D Taylor, Paul Workman, Richard J Gilbertson
May 07, 2019
Despite decades of research, brain tumours remain among the deadliest of all forms of cancer. The ability of these tumours to resist almost all conventional and novel treatments relates, in part, to the unique cell-intrinsic and...
Metastatic chromophobe renal cell carcinoma treated with targeted therapies
E Colomba, G Le Teuff, T Eisen, GD Stewart, K Fife, J Larkin, A Biondo, L Pickering, A Srinivasan, H Boyle, L Derosa, CN Sternberg, F Recine, C Ralph, C Saldana, P Barthelemy, JC Bernhard, H Gurney, G Verhoest, E Vauleon, P Bigot, J Berger, C Pfister, G Gravis, J-M Rodier, S Culine, A Caty, F Rolland, F Priou, B Escudier, L Albiges
Jul 31, 2017
$\textbf{Background}$
Treatment of non–clear cell renal cell carcinoma (RCC) remains controversial despite several recent prospective studies of targeted therapies (TT). Often Vascular Endothelial growth Factor (VEGF) and...
Engineering Genetic Predisposition in Human Neuroepithelial Stem Cells Recapitulates Medulloblastoma Tumorigenesis.
Miller Huang, Jignesh Tailor, Qiqi Zhen, Aaron H Gillmor, Matthew L Miller, Holger Weishaupt, Justin Chen, Tina Zheng, Emily K Nash, Lauren K McHenry, Zhenyi An, Fubaiyang Ye, Yasuhiro Takashima, James Clarke, Harold Ayetey, Florence MG Cavalli, Betty Luu, Branden S Moriarity, Shirin Ilkhanizadeh, Lukas Chavez, Chunying Yu, Kathreena M Kurian, Thierry Magnaldo, Nicolas Sevenet, Philipp Koch, Steven M Pollard, Peter Dirks, Michael P Snyder, David A Largaespada, Yoon Jae Cho, Joanna J Phillips, Fredrik J Swartling, A Sorana Morrissy, Marcel Kool, Stefan M Pfister, Michael D Taylor, Austin Smith, William A Weiss
Jul 25, 2019
Human neural stem cell cultures provide progenitor cells that are potential cells of origin for brain cancers. However, the extent to which genetic predisposition to tumor formation can be faithfully captured in stem cell lines...
SHH Human pluripotent stem cells Medulloblastoma neuroepithelial stem cells Animals Basal Cell Nevus Syndrome Brain Neoplasms Carcinogenesis DEAD-box RNA Helicases Disease Models Animal Genetic Engineering Genetic Predisposition to Disease Humans Medulloblastoma Mice Mice SCID N-Myc Proto-Oncogene Protein Neoplasm Proteins Neural Stem Cells Neuroepithelial Cells Patched-1 Receptor Pluripotent Stem Cells Stem Cell Transplantation Transplantation Heterologous
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