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Results: 254
Expression of genes associated with immunity in the endometrium of cattle with disparate postpartum uterine disease and fertility.
Shan Herath, Sonia T Lilly, Natalia R Santos, Robert O Gilbert, Leopold Goetze, Clare E Bryant, John O White, James Cronin, I Martin Sheldon
Jun 16, 2011
Animals Biopsy Cattle Cattle Diseases Cytokines Endometrium Female Fertility Gene Expression Infections Infertility female Leukocyte Common Antigens Lipopolysaccharide Receptors Lymphocyte Antigen 96 Nod1 Signaling Adaptor Protein Postpartum Period Protein Serine-Threonine Kinases Receptor Transforming Growth Factor-beta Type I Receptors Prostaglandin Receptors Transforming Growth Factor beta Toll-Like Receptors Uterine Diseases
Neural activity in human ventromedial prefrontal cortex reflecting the intention to save reward.
Saving behavior usually requires individuals to perform several consecutive choices before collecting the final reward. The overt behavior is preceded by an intention to perform an appropriate choice sequence. We studied saving...
Neural Basis for Economic Saving Strategies in Human Amygdala-Prefrontal Reward Circuits.
Economic saving is an elaborate behavior in which the goal of a reward in the future directs planning and decision-making in the present. Here, we measured neural activity while subjects formed simple economic saving strategies...
Structural model of FeoB, the iron transporter from Pseudomonas aeruginosa, predicts a cysteine lined, GTP-gated pore.
Saeed Seyedmohammad, Natalia Alveal Fuentealba, Robert AJ Marriott, Tom A Goetze, J Michael Edwardson, Nelson P Barrera, Henrietta Venter
Mar 02, 2016
The ribosomal P-stalk couples amino acid starvation to GCN2 activation in mammalian cells.
Heather P Harding, Adriana Ordonez, Felicity Allen, Leopold Parts, Alison J Inglis, Roger L Williams, David Ron
Jan 03, 2020
The eukaryotic translation initiation factor 2a (eIF2a) kinase GCN2 is activated by amino acid starvation to elicit a rectifying physiological program known as the Integrated Stress Response (ISR). A role for uncharged tRNAs as...
The ribosomal P-stalk couples amino acid starvation to GCN2 activation in mammalian cells
Heather P Harding, Adriana Ordonez, Felicity Allen, Leopold Parts, Alison J Inglis, Roger L Williams, David Ron
Dec 19, 2019
The eukaryotic translation initiation factor 2α (eIF2α) kinase GCN2 is activated by amino acid starvation to elicit a rectifying physiological program known as the Integrated Stress Response (ISR). A role for uncharged tRNAs as...
The Lantern Vol. 52, No. 1, Fall 1985
Sally Stricker, Alison J. Graf, Geoffrey Allen, Alfred L. Creager, Christopher Harbach, Debra Ritter, Timothy S. Weible, Rebecca Moore, Stephen Pote, Jennifer Healy, Samuel C. Conway, Beth Henderson, Trisha Carvelli, Sue Darley, Angela M. Salas, Craig DiLouie, Beth Riccio, Kevin Trayner, Bill Connolly
Jan 01, 0001
Nudes Orion Fragments of an Epic Sunrise The Planting Season Nursing Home Hope Chest Childhood Swing Relationships Elroy, Leopold, and Max Urban Dragon The Farmer's Wife A Ballad of Two Lovers ...
Ursinus College Collegeville Pennsylvania Lantern Literary Magazine poetry fiction Creative Nonfiction Arts and Humanities Creative Writing fiction illustration Nonfiction poetry
Published by: Ursinus College
Plasma marker for systemic inflammation is increased in Mexican Tarahumara following ultra-distance running.
Peter Durand Skottrup, Thomas Kallemose, Diana Espino, Rocio Infante-Ramirez, Soren Brage, Dijana Terzic, Jens Peter Goetze, Jesper Kjaergaard, Dirk Lund Christensen
Aug 17, 2020
Lesions to right posterior parietal cortex impair visual depth perception from disparity but not motion cues.
The ribosomal P-stalk couples amino acid starvation to GCN2 activation in mammalian cells.
Heather P Harding, Adriana Ordonez, Felicity Allen, Leopold Parts, Alison J Inglis, Roger L Williams, David Ron
Nov 21, 2019
CHO GCN2 P-stalk Cell Biology Genetics Genomics integrated stress response p1 p2 ribosome stalling ul10 Amino Acids Animals CHO Cells CRISPR-Cas Systems Cricetulus Endoplasmic Reticulum Gene Expression Regulation Enzymologic HeLa Cells Humans Kinetics Ligands Mice Models Molecular Mutagenesis Phosphorylation Protein Binding Protein Conformation Protein Serine-Threonine Kinases Protein Unfolding RNA Transfer Ribosomes Signal Transduction Starvation Transcriptome eIF-2 Kinase
Dermatopharmacokinetics of betamethasone 17-valerate
The objective was to compare the in vivo distribution profiles of betamethasone 17-valerate (BMV) across the stratum corneum (SC) following (a) delivery from gelled and un-gelled formulations, and (b) two different skin cleaning...
Depletion of Macrophages Improves Therapeutic Response to Gemcitabine in Murine Pancreas Cancer.
Soeren M Buchholz, Robert G Goetze, Shiv K Singh, Christoph Ammer-Herrmenau, Frances M Richards, Duncan I Jodrell, Malte Buchholz, Patrick Michl, Volker Ellenrieder, Elisabeth Hessmann, Albrecht Neesse
Sep 01, 2020
BACKGROUND: The tumor microenvironment (TME) is composed of fibro-inflammatory cells and extracellular matrix (ECM) components. However, the exact contribution of the various TME compartments towards therapeutic response is...
Perceptual memory drives learning of retinotopic biases for bistable stimuli.
The visual system exploits past experience at multiple timescales to resolve perceptual ambiguity in the retinal image. For example, perception of a bistable stimulus can be biased toward one interpretation over another when...
“Shylock's Return”
Dror Abend-David
Jan 01, 2020
This article addresses monetary, cultural, political and religious transactions, exchanges, conversions and translations between Jews and non-Jews in the play, “The Merchant of Venice,” in relation with Hebrew performances of...
Published by: IGI Global Scientific Publishing
Dermatopharmacokinetics of betamethasone 17-valerate
The objective was to compare the in vivo distribution profiles of betamethasone 17-valerate (BMV) across the stratum corneum (SC) following (a) delivery from gelled and un-gelled formulations, and (b) two different skin cleaning...
SPARC dependent collagen deposition and gemcitabine delivery in a genetically engineered mouse model of pancreas cancer.
Iswarya Ramu, Sören M Buchholz, Melanie S Patzak, Robert G Goetze, Shiv K Singh, Frances M Richards, Duncan I Jodrell, Bence Sipos, Philipp Ströbel, Volker Ellenrieder, Elisabeth Hessmann, Albrecht Neesse
Oct 29, 2019
BACKGROUND: Pancreatic ductal adenocarcinoma (PDAC) is characterised by extensive matrix deposition that has been implicated in impaired drug delivery and therapeutic resistance. Secreted protein acidic and rich in cysteine...
Transient cardiac dysfunction but elevated cardiac and kidney biomarkers 24 h following an ultra-distance running event in Mexican Tarahumara.
Dirk L Christensen, Diana Espino, Rocío Infante-Ramírez, Mónica S Cervantes-Borunda, Rosa P Hernández-Torres, Antonio E Rivera-Cisneros, Daniel Castillo, Kate Westgate, Dijana Terzic, Soren Brage, Christian Hassager, Jens P Goetze, Jesper Kjaergaard
Mar 22, 2018
BACKGROUND: The Mexican Tarahumara are accustomed to running ultra-distance races. No data exist on the acute physiological changes following ultra-distance running and physiological-biomarker associations in this population....
Cytosolic 5'-nucleotidase 1A is overexpressed in pancreatic cancer and mediates gemcitabine resistance by reducing intracellular gemcitabine metabolites.
Melanie S Patzak, Vijayalakshmi Kari, Shilpa Patil, Feda H Hamdan, Robert G Goetze, Marius Brunner, Jochen Gaedcke, Julia Kitz, Duncan I Jodrell, Frances M Richards, Christian Pilarsky, Robert Gruetzmann, Petra Rümmele, Thomas Knösel, Elisabeth Hessmann, Volker Ellenrieder, Steven A Johnsen, Albrecht Neesse
Mar 19, 2019
BACKGROUND: Cytosolic 5'-nucleotidase 1A (NT5C1A) dephosphorylates non-cyclic nucleoside monophosphates to produce nucleosides and inorganic phosphates. Here, we investigate NT5C1A expression in pancreatic ductal adenocarcinoma...
Chemotherapeutic resistance Cytosolic 5′-nucleotidase 1A Gemcitabine pancreatic cancer 5'-Nucleotidase Animals Biomarkers Tumor Carcinoma Pancreatic Ductal Cell Line Tumor Deoxycytidine Disease Models Animal Drug Resistance Neoplasm Gene Expression Humans Mice Mice Transgenic Models Biological Pancreatic Neoplasms Prognosis Xenograft Model Antitumor Assays Gemcitabine
Using genetic algorithms to systematically improve the synthesis conditions of Al-PMOF.
Nency P Domingues, Seyed Mohamad Moosavi, Leopold Talirz, Kevin Maik Jablonka, Christopher P Ireland, Fatmah Mish Ebrahim, Berend Smit
Feb 25, 2023
The synthesis of metal-organic frameworks (MOFs) is often complex and the desired structure is not always obtained. In this work, we report a methodology that uses a joint machine learning and experimental approach to optimize...
Published by: Communications chemistry
Ursinus College Alumni Journal, August 1968
Richard P. Richter, Donald C. Estes, Lucille Hunt Bone, Roger P. Staiger, Raymond V. Gurzynski, Adele Boyd, Patricia Leopold, Donald L. Helfferich, Linda Grace Hoyer
Jan 01, 0001
A special responsibility Capp quips cleverly at commencement Alumni Day '68: The happy time; The business of the day; Election winners take office; Two distinguished graduates honored; A salute to individuals & organizations;...
Ursinus College Collegeville Pennsylvania alumni Deaths Marriages Al Capp Austin Gavin Marion Spangler Studio Cottage Linda Grace Hoyer James E. Wagner Middle States Association Higher Education Social History United States History
Published by: Ursinus College
"yes I said yes I will Yes": Queer Performativity and Realization of the Erotic in James Joyce's Ulysses
Brian K. Cox
Jan 01, 0001
This project confronts the theoretical concepts of queer gender performativity and the erotic in James Joyce's Ulysses. Scholars have long asserted the importance of this text in discussing notions of traditionally constructed...
Joyce Ulysses gender performativity queer performativity Queer Theory Arts and Humanities English Language and Literature
Published by: Ursinus College
Binding of ISRIB reveals a regulatory site in the nucleotide exchange factor eIF2B.
Alisa F Zyryanova, Félix Weis, Alexandre Faille, Akeel Abo Alard, Ana Crespillo-Casado, Yusuke Sekine, Heather P Harding, Felicity Allen, Leopold Parts, Christophe Fromont, Peter M Fischer, Alan J Warren, David Ron
Apr 04, 2018
Predicting the mutations generated by repair of Cas9-induced double-strand breaks.
Felicity Allen, Luca Crepaldi, Clara Alsinet, Alexander J Strong, Vitalii Kleshchevnikov, Pietro De Angeli, Petra Páleníková, Anton Khodak, Vladimir Kiselev, Michael Kosicki, Andrew R Bassett, Heather Harding, Yaron Galanty, Francisco Muñoz-Martínez, Emmanouil Metzakopian, Stephen P Jackson, Leopold Parts
Dec 13, 2018
The DNA mutation produced by cellular repair of a CRISPR-Cas9-generated double-strand break determines its phenotypic effect. It is known that the mutational outcomes are not random, but depend on DNA sequence at the targeted...
The Ursinus Weekly, November 3, 1952
Sarah Canan, Ralph Sternberg, William Lukens, Richard P. Richter, Joan Higgins, Helen Lightfoot, Helen Yost, Sallie Lumis, Ted Wenner, Patricia Garrow, Katharine Hood, Dick Bowman
Jan 01, 0001
Rushees sign sorority bids Saturday morn Girls plan fashion show Dr. Wagner gives med school advice Freshmen hear Dr. Helfferich Students discuss social life ideas at fireside chat WSGA enforces poster removal Quartet to...
Ursinus College Collegeville Pennsylvania newspaper sororities rushing Women Day Students Brownback-Anders pre-medical society Paul Wagner Donald L. Helfferich student government YMCA YWCA Dwight D. Eisenhower Campus Chest Curtain Club Business Administration Club H. Donaldson Leopold Halloween Adlai Stevenson Fred Reiss Russ McConnell Isolina Torres Student Teaching field hockey Football Dick Glock Bob Swett Marjorie Merrifield Audrey Rittenhouse Edna Seifert Intramural Sports French Club Doris Thompson Ernest A. Roemer Agnes Marie Murphy John H. Schrader cultural history Higher Education Liberal Studies Social History United States History
Published by: Ursinus College
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