Pluripotent state transitions coordinate morphogenesis in mouse and human embryos.
Marta N Shahbazi,
Antonio Scialdone,
Natalia Skorupska,
Antonia Weberling,
Gaelle Recher,
Meng Zhu,
Agnieszka Jedrusik,
Liani G Devito,
Laila Noli,
Iain C Macaulay,
Christa Buecker,
Yakoub Khalaf,
Dusko Ilic,
Thierry Voet,
John C Marioni,
Magdalena Zernicka-Goetz
Jun 08, 2018
The foundations of mammalian development lie in a cluster of embryonic epiblast stem cells. In response to extracellular matrix signalling, these cells undergo epithelialization and create an apical surface in contact with a...