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Results: 75
Mendelian neurodegenerative disease genes involved in autophagy.
Eleanna Stamatakou, Lidia Wróbel, Sandra Malmgren Hill, Claudia Puri, Sung Min Son, Motoki Fujimaki, Ye Zhu, Farah Siddiqi, Marian Fernandez-Estevez, Marco M Manni, So Jung Park, Julien Villeneuve, David Chaim Rubinsztein
Mar 12, 2020
The lysosomal degradation pathway of macroautophagy (herein referred to as autophagy) plays a crucial role in cellular physiology by regulating the removal of unwanted cargoes such as protein aggregates and damaged organelles....
Sleep Paralysis among Professional Firefighters and a Possible Association with PTSD—Online Survey-Based Study
Paulina Wróbel-Knybel, Joanna Rog, Baland Jalal, Paweł Szewczyk, Hanna Karakuła-Juchnowicz
Sep 09, 2021
The prevalence of sleep paralysis (SP) is estimated at approximately 7.6% of the world’s general population. One of the strongest factors in the onset of SP is PTSD, which is often found among professional firefighters. Our...
Risk factors of sleep paralysis in a population of Polish students.
Paulina Wróbel-Knybel, Michał Flis, Joanna Rog, Baland Jalal, Hanna Karakuła-Juchnowicz
Jun 07, 2022
BACKGROUND: Sleep paralysis (SP) is a transitional dissociative state associated with the REM sleep phase that affects approximately 28.3% of the student population during their lifetime. The reasons for the high prevalence of...
Post-translational modifications of Beclin 1 provide multiple strategies for autophagy regulation.
Autophagy is a conserved intracellular degradation pathway essential for protein homeostasis, survival and development. Defects in autophagic pathways have been connected to a variety of human diseases, including cancer and...
Characteristics of Sleep Paralysis and Its Association with Anxiety Symptoms, Perceived Stress, PTSD, and Other Variables Related to Lifestyle in Selected High Stress Exposed Professions.
Paulina Wróbel-Knybel, Michał Flis, Joanna Rog, Baland Jalal, Leszek Wołkowski, Hanna Karakuła-Juchnowicz
Aug 08, 2022
Sleep paralysis (SP) is a hypnagogic or hypnopompic state associated with the inability to move while conscious. Recurrent isolated sleep paralysis (RISP) is a type of REM parasomnia. Individuals experiencing anxiety disorders...
Female university students' preferences for different types of sexual relationships
BACKGROUND: Gender-based violence among young women is a growing problem worldwide. The consequences of this victimization have been well reported in the scientific literature, among which negative health outcomes stand out. The...
Prevalence and Clinical Picture of Sleep Paralysis in a Polish Student Sample.
Paulina Wróbel-Knybel, Hanna Karakuła-Juchnowicz, Michał Flis, Joanna Rog, Devon E Hinton, Piotr Boguta, Baland Jalal
May 19, 2020
Sleep paralysis (SP) is a psychobiological phenomenon caused by temporary desynchrony in the architecture of rapid eye movement (REM) sleep. It affects approximately 7.6% of the general population during their lifetime. The aim...
Chronic Illnesses, Vulnerability, and Uncertainty
The goal of this chapter is to describe some of the recent challenges that modern medicine is facing using patient-centered medicine as a theoretical frame of reference. First, the work will describe the origin, the development...
Published by: IGI Global Scientific Publishing
Sleep Paralysis among Professional Firefighters and a Possible Association with PTSD-Online Survey-Based Study.
Paulina Wróbel-Knybel, Joanna Rog, Baland Jalal, Paweł Szewczyk, Hanna Karakuła-Juchnowicz
Oct 29, 2021
The prevalence of sleep paralysis (SP) is estimated at approximately 7.6% of the world's general population. One of the strongest factors in the onset of SP is PTSD, which is often found among professional firefighters. Our...
In Vitro Influence of Mycophenolic Acid on Selected Parameters of Stimulated Peripheral Canine Lymphocytes.
Mycophenolic acid (MPA) is an active metabolite of mycophenolate mofetil, a new immunosuppressive drug effective in the treatment of canine autoimmune diseases. The impact of MPA on immunity is ambiguous and its influence on the...
Symptom appraisal in uncertainty
Lauren C. Heathcote, Nele Loecher, Pamela Simon, Sheri Spunt, Abbie Jordan, Perri Tutelman, Sarah Cunningham, Lidia Schapira, Laura Simons
Dec 31, 2021
Objective: Somatic symptoms capture attention, demand interpretation, and promote health behaviors. Symptom appraisal is particularly impactful within uncertain health contexts such as cancer survivorship. Yet, little is known...
Activation-dependent substrate recruitment by the eukaryotic translation initiation factor 2 kinase PERK.
Regulated phosphorylation of the alpha subunit of eukaryotic translation initiation factor 2 (eIF2alpha) by the endoplasmic reticulum (ER) stress-activated protein kinase PERK modulates protein synthesis and couples the...
Nest desertion is not predicted by cuckoldry in the Eurasian penduline tit
Rene E Van Dijk, Lidia A Mészáros, Marco Velde, T Székely, A Pogány, J Szabad, Jan Komdeur
Sep 01, 2010
Engagement in extra-pair copulations is an example of the abundant conflicting interests between males and females over reproduction. Potential benefits for females and the risk of cuckoldry for males are expected to have...
Astrocytes actively support long-range molecular clock synchronization of segregated neuronal populations.
Lidia Giantomasi, João F Ribeiro, Olga Barca-Mayo, Mario Malerba, Ermanno Miele, Davide De Pietri Tonelli, Luca Berdondini
Mar 24, 2023
Nest desertion is not predicted by cuckoldry in the Eurasian penduline tit
Rene E Van Dijk, Lidia A Mészáros, Marco Velde, T Székely, A Pogány, J Szabad, Jan Komdeur
Sep 01, 2010
Engagement in extra-pair copulations is an example of the abundant conflicting interests between males and females over reproduction. Potential benefits for females and the risk of cuckoldry for males are expected to have...
Symptom appraisal in uncertainty
Lauren C. Heathcote, Nele Loecher, Pamela Simon, Sheri Spunt, Abbie Jordan, Perri Tutelman, Sarah Cunningham, Lidia Schapira, Laura Simons
Dec 31, 2021
Objective: Somatic symptoms capture attention, demand interpretation, and promote health behaviors. Symptom appraisal is particularly impactful within uncertain health contexts such as cancer survivorship. Yet, little is known...
GPVI surface expression and signalling pathway activation are increased in platelets from obese patients
María N Barrachina, Aurelio M Sueiro, Irene Izquierdo, Lidia Hermida-Nogueira, Esteban Guitián, Felipe F Casanueva, Richard W Farndale, Masaaki Moroi, Stephanie M Jung, María Pardo, Ángel García
Jan 30, 2019
Drug targets GPVI signalling obesity platelets Proteomics SFK-Mediated signalling pathways Adolescent Adult Blood Platelets Body Mass Index Case-Control Studies Female Humans Male obesity Phospholipase C gamma Phosphorylation Platelet Activation Platelet Aggregation Platelet Membrane Glycoproteins Signal Transduction Up-Regulation Young Adult
Breaking the electrical barrier between copper and carbon nanotubes.
Karolina Z Milowska, Mahdi Ghorbani-Asl, Marek Burda, Lidia Wolanicka, Nordin Ćatić, Paul D Bristowe, Krzysztof KK Koziol
Nov 20, 2018
Improving the interface between copper and carbon nanotubes (CNTs) offers a straightforward strategy for the effective manufacturing and utilisation of Cu-CNT composite material that could be used in various industries including...
Homozygous GDF2 nonsense mutations result in a loss of circulating BMP9 and BMP10 and are associated with either PAH or an "HHT-like" syndrome in children.
Joshua Hodgson, Lidia Ruiz-Llorente, Jamie McDonald, Oliver Quarrell, Kelechi Ugonna, James Bentham, Rebecca Mason, Jennifer Martin, David Moore, Katie Bergstrom, Pinar Bayrak-Toydemir, Whitney Wooderchak-Donahue, Nicholas Morrell, Robin Condliffe, Carmelo Bernabeu, Paul Upton
Mar 23, 2021
BACKGROUND: Disrupted endothelial BMP9/10 signaling may contribute to the pathophysiology of both hereditary hemorrhagic telangiectasia (HHT) and pulmonary arterial hypertension (PAH), yet loss of circulating BMP9 has not been...
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