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Climate change modulates the stratospheric volcanic sulfate aerosol lifecycle and radiative forcing from tropical eruptions.
Explosive volcanic eruptions affect climate, but how climate change affects the stratospheric volcanic sulfate aerosol lifecycle and radiative forcing remains unexplored. We combine an eruptive column model with an...
Published by: Nature Communications
Climate change modulates the stratospheric volcanic sulfate aerosol lifecycle and radiative forcing from tropical eruptions
Abstract: Explosive volcanic eruptions affect climate, but how climate change affects the stratospheric volcanic sulfate aerosol lifecycle and radiative forcing remains unexplored. We combine an eruptive column model with an...
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Impact of climate change on volcanic processes
Abstract: The impacts of volcanic eruptions on climate are increasingly well understood, but the mirror question of how climate changes affect volcanic systems and processes, which we term “climate-volcano impacts”, remains...
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Identification of susceptibility loci for Takayasu arteritis through a large multi-ancestral genome-wide association study.
Takayasu arteritis is a rare inflammatory disease of large arteries. We performed a genetic study in Takayasu arteritis comprising 6,670 individuals (1,226 affected individuals) from five different populations. We discovered HLA...
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GWAS on longitudinal growth traits reveals different genetic factors influencing infant, child, and adult BMI.
Alexessander Couto Alves, N Maneka G De Silva, Ville Karhunen, Ulla Sovio, Shikta Das, H Rob Taal, Nicole M Warrington, Alexandra M Lewin, Marika Kaakinen, Diana L Cousminer, Elisabeth Thiering, Nicholas J Timpson, Tom A Bond, Estelle Lowry, Christopher D Brown, Xavier Estivill, Virpi Lindi, Jonathan P Bradfield, Frank Geller, Doug Speed, Lachlan J M Coin, Marie Loh, Sheila J Barton, Lawrence J Beilin, Hans Bisgaard, Klaus Bønnelykke, Rohia Alili, Ida J Hatoum, Katharina Schramm, Rufus Cartwright, Marie-Aline Charles, Vincenzo Salerno, Karine Clément, Annique A J Claringbould, Cornelia M van Duijn, Elena Moltchanova, Johan G Eriksson, Cathy Elks, Bjarke Feenstra, Claudia Flexeder, Stephen Franks, Timothy M Frayling, Rachel M Freathy, Paul Elliott, Elisabeth Widén, Hakon Hakonarson, Andrew T Hattersley, Alina Rodriguez, Marco Banterle, Joachim Heinrich, Barbara Heude, John W Holloway, Albert Hofman, Elina Hyppönen, Hazel Inskip, Lee M Kaplan, Asa K Hedman, Esa Läärä, Holger Prokisch, Harald Grallert, Timo A Lakka, Debbie A Lawlor, Mads Melbye, Tarunveer S Ahluwalia, Marcella Marinelli, Iona Y Millwood, Lyle J Palmer, Craig E Pennell, John R Perry, Susan M Ring, Markku J Savolainen, Fernando Rivadeneira, Marie Standl, Jordi Sunyer, Carla M T Tiesler, Andre G Uitterlinden, William Schierding, Justin M O'Sullivan, Inga Prokopenko, Karl-Heinz Herzig, George Davey Smith, Paul O'Reilly, Janine F Felix, Jessica L Buxton, Alexandra I F Blakemore, Ken K Ong, Vincent W V Jaddoe, Struan F A Grant, Sylvain Sebert, Mark I McCarthy, Marjo-Riitta Järvelin
Jan 24, 2020
Early childhood growth patterns are associated with adult health, yet the genetic factors and the developmental stages involved are not fully understood. Here, we combine genome-wide association studies with modeling of...
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GWAS on longitudinal growth traits reveals different genetic factors influencing infant, child, and adult BMI
Alexessander Couto Alves, N Maneka G De Silva, Ville Karhunen, Ulla Sovio, Shikta Das, H Rob Taal, Nicole M Warrington, Alexandra M Lewin, Marika Kaakinen, Diana L Cousminer, Elisabeth Thiering, Nicholas J Timpson, Tom A Bond, Estelle Lowry, Christopher D Brown, Xavier Estivill, Virpi Lindi, Jonathan P Bradfield, Frank Geller, Doug Speed, Lachlan JM Coin, Marie Loh, Sheila J Barton, Lawrence J Beilin, Hans Bisgaard, Klaus Bønnelykke, Rohia Alili, Ida J Hatoum, Katharina Schramm, Rufus Cartwright, Marie-Aline Charles, Vincenzo Salerno, Karine Clément, Annique AJ Claringbould, Cornelia M van Duijn, Elena Moltchanova, Johan G Eriksson, Cathy Elks, Bjarke Feenstra, Claudia Flexeder, Stephen Franks, Timothy M Frayling, Rachel M Freathy, Paul Elliott, Elisabeth Widén, Hakon Hakonarson, Andrew T Hattersley, Alina Rodriguez, Marco Banterle, Joachim Heinrich, Barbara Heude, John W Holloway, Albert Hofman, Elina Hyppönen, Hazel Inskip, Lee M Kaplan, Asa K Hedman, Esa Läärä, Holger Prokisch, Harald Grallert, Timo A Lakka, Debbie A Lawlor, Mads Melbye, Tarunveer S Ahluwalia, Marcella Marinelli, Iona Y Millwood, Lyle J Palmer, Craig E Pennell, John R Perry, Susan M Ring, Markku J Savolainen, Fernando Rivadeneira, Marie Standl, Jordi Sunyer, Carla MT Tiesler, Andre G Uitterlinden, William Schierding, Justin M O’Sullivan, Inga Prokopenko, Karl-Heinz Herzig, George Davey Smith, Paul O'Reilly, Janine F Felix, Jessica L Buxton, Alexandra If Blakemore, Ken K Ong, Vincent WV Jaddoe, Struan FA Grant, Sylvain Sebert, Mark I McCarthy, Marjo-Riitta Järvelin
Oct 08, 2019
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A multilaboratory comparison of calibration accuracy and the performance of external references in analytical ultracentrifugation.
Huaying Zhao, Rodolfo Ghirlando, Carlos Alfonso, Fumio Arisaka, Ilan Attali, David L Bain, Marina M Bakhtina, Donald F Becker, Gregory J Bedwell, Ahmet Bekdemir, Tabot MD Besong, Catherine Birck, Chad A Brautigam, William Brennerman, Olwyn Byron, Agnieszka Bzowska, Jonathan B Chaires, Catherine T Chaton, Helmut Cölfen, Keith D Connaghan, Kimberly A Crowley, Ute Curth, Tina Daviter, William L Dean, Ana I Díez, Christine Ebel, Debra M Eckert, Leslie E Eisele, Edward Eisenstein, Patrick England, Carlos Escalante, Jeffrey A Fagan, Robert Fairman, Ron M Finn, Wolfgang Fischle, José García de la Torre, Jayesh Gor, Henning Gustafsson, Damien Hall, Stephen E Harding, José G Hernández Cifre, Andrew B Herr, Elizabeth E Howell, Richard S Isaac, Shu-Chuan Jao, Davis Jose, Soon-Jong Kim, Bashkim Kokona, Jack A Kornblatt, Dalibor Kosek, Elena Krayukhina, Daniel Krzizike, Eric A Kusznir, Hyewon Kwon, Adam Larson, Thomas M Laue, Aline Le Roy, Andrew P Leech, Hauke Lilie, Karolin Luger, Juan R Luque-Ortega, Jia Ma, Carrie A May, Ernest L Maynard, Anna Modrak-Wojcik, Yee-Foong Mok, Norbert Mücke, Luitgard Nagel-Steger, Geeta J Narlikar, Masanori Noda, Amanda Nourse, Tomas Obsil, Chad K Park, Jin-Ku Park, Peter D Pawelek, Erby E Perdue, Stephen J Perkins, Matthew A Perugini, Craig L Peterson, Martin G Peverelli, Grzegorz Piszczek, Gali Prag, Peter E Prevelige, Bertrand DE Raynal, Lenka Rezabkova, Klaus Richter, Alison E Ringel, Rose Rosenberg, Arthur J Rowe, Arne C Rufer, David J Scott, Javier G Seravalli, Alexandra S Solovyova, Renjie Song, David Staunton, Caitlin Stoddard, Katherine Stott, Holger M Strauss, Werner W Streicher, John P Sumida, Sarah G Swygert, Roman H Szczepanowski, Ingrid Tessmer, Ronald T Toth, Ashutosh Tripathy, Susumu Uchiyama, Stephan FW Uebel, Satoru Unzai, Anna Vitlin Gruber, Peter H von Hippel, Christine Wandrey, Szu-Huan Wang, Steven E Weitzel, Beata Wielgus-Kutrowska, Cynthia Wolberger, Martin Wolff, Edward Wright, Yu-Sung Wu, Jacinta M Wubben, Peter Schuck
Jan 16, 2018
Analytical ultracentrifugation (AUC) is a first principles based method to determine absolute sedimentation coefficients and buoyant molar masses of macromolecules and their complexes, reporting on their size and shape in free...
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Novel loci for childhood body mass index and shared heritability with adult cardiometabolic traits
Suzanne Vogelezang, Jonathan P. Bradfield, Tarunveer S. Ahluwalia, John A. Curtin, Timo A. Lakka, Niels Grarup, Markus Scholz, Peter J. van der Most, Claire Monnereau, Evie Stergiakouli, Anni Heiskala, Momoko Horikoshi, Iryna O. Fedko, Natalia Vilor-Tejedor, Diana L. Cousminer, Marie Standl, Carol A. Wang, Jorma Viikari, Frank Geller, Carmen Íñiguez, Niina Pitkänen, Alessandra Chesi, Jonas Bacelis, Loic Yengo, Maties Torrent, Ioanna Ntalla, Øyvind Helgeland, Saskia Selzam, Judith M. Vonk, Mohammed H. Zafarmand, Barbara Heude, Ismaa Sadaf Farooqi, Akram Alyass, Robin N. Beaumont, Christian T. Have, Peter Rzehak, Jose Ramon Bilbao, Theresia M. Schnurr, Inês Barroso, Klaus Bønnelykke, Lawrence J. Beilin, Lisbeth Carstensen, Marie-Aline Charles, Bo Chawes, Karine Clément, Ricardo Closa-Monasterolo, Adnan Custovic, Johan G. Eriksson, Joaquin Escribano, Maria Groen-Blokhuis, Veit Grote, Dariusz Gruszfeld, Hakon Hakonarson, Torben Hansen, Andrew T. Hattersley, Mette Hollensted, Jouke-Jan Hottenga, Elina Hyppönen, Stefan Johansson, Raimo Joro, Mika Kähönen, Ville Karhunen, Wieland Kiess, Bridget A. Knight, Berthold Koletzko, Andreas Kühnapfel, Kathrin Landgraf, Jean-Paul Langhendries, Terho Lehtimäki, Jaakko T. Leinonen, Aihuali Li, Virpi Lindi, Estelle Lowry, Mariona Bustamante, Carolina Medina-Gomez, Mads Melbye, Kim F. Michaelsen, Camilla S. Morgen, Trevor A. Mori, Tenna R. H. Nielsen, Harri Niinikoski, Albertine J. Oldehinkel, Katja Pahkala, Kalliope Panoutsopoulou, Oluf Pedersen, Craig E. Pennell, Christine Power, Sijmen A. Reijneveld, Fernando Rivadeneira, Angela Simpson, Peter D. Sly, Jakob Stokholm, Kook K. Teo, Elisabeth Thiering, Nicholas J. Timpson, André G. Uitterlinden, Catharina E. M. van Beijsterveldt, Barbera D. C. van Schaik, Marc Vaudel, Elvira Verduci, Rebecca K. Vinding, Mandy Vogel, Eleftheria Zeggini, Sylvain Sebert, Mads V. Lind, Christopher D. Brown, Loreto Santa-Marina, Eva Reischl, Christine Frithioff-Bøjsøe, David Meyre, Eleanor Wheeler, Ken Ong, Ellen A. Nohr, Tanja G. M. Vrijkotte, Gerard H. Koppelman, Robert Plomin, Pål R. Njølstad, George D. Dedoussis, Philippe Froguel, Thorkild I. A. Sørensen, Bo Jacobsson, Rachel M. Freathy, Babette S. Zemel, Olli Raitakari, Martine Vrijheid, Bjarke Feenstra, Leo-Pekka Lyytikäinen, Harold Snieder, Holger Kirsten, Patrick G. Holt, Joachim Heinrich, Elisabeth Widén, Jordi Sunyer, Dorret I. Boomsma, Marjo-Riitta Järvelin, Antje Körner, George Davey Smith, Jens-Christian Holm, Mustafa Atalay, Clare Murray, Hans Bisgaard, Mark I. McCarthy, Early Growth Genetics Consortium, Vincent W. V. Jaddoe, Struan F. A. Grant, Janine F. Felix
Oct 22, 2020
The genetic background of childhood body mass index (BMI), and the extent to which the well-known associations of childhood BMI with adult diseases are explained by shared genetic factors, are largely unknown. We performed a...
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Novel loci for childhood body mass index and shared heritability with adult cardiometabolic traits.
Suzanne Vogelezang, Jonathan P Bradfield, Tarunveer S Ahluwalia, John A Curtin, Timo A Lakka, Niels Grarup, Markus Scholz, Peter J van der Most, Claire Monnereau, Evie Stergiakouli, Anni Heiskala, Momoko Horikoshi, Iryna O Fedko, Natalia Vilor-Tejedor, Diana L Cousminer, Marie Standl, Carol A Wang, Jorma Viikari, Frank Geller, Carmen Íñiguez, Niina Pitkänen, Alessandra Chesi, Jonas Bacelis, Loic Yengo, Maties Torrent, Ioanna Ntalla, Øyvind Helgeland, Saskia Selzam, Judith M Vonk, Mohammed H Zafarmand, Barbara Heude, Ismaa Sadaf Farooqi, Akram Alyass, Robin N Beaumont, Christian T Have, Peter Rzehak, Jose Ramon Bilbao, Theresia M Schnurr, Inês Barroso, Klaus Bønnelykke, Lawrence J Beilin, Lisbeth Carstensen, Marie-Aline Charles, Bo Chawes, Karine Clément, Ricardo Closa-Monasterolo, Adnan Custovic, Johan G Eriksson, Joaquin Escribano, Maria Groen-Blokhuis, Veit Grote, Dariusz Gruszfeld, Hakon Hakonarson, Torben Hansen, Andrew T Hattersley, Mette Hollensted, Jouke-Jan Hottenga, Elina Hyppönen, Stefan Johansson, Raimo Joro, Mika Kähönen, Ville Karhunen, Wieland Kiess, Bridget A Knight, Berthold Koletzko, Andreas Kühnapfel, Kathrin Landgraf, Jean-Paul Langhendries, Terho Lehtimäki, Jaakko T Leinonen, Aihuali Li, Virpi Lindi, Estelle Lowry, Mariona Bustamante, Carolina Medina-Gomez, Mads Melbye, Kim F Michaelsen, Camilla S Morgen, Trevor A Mori, Tenna RH Nielsen, Harri Niinikoski, Albertine J Oldehinkel, Katja Pahkala, Kalliope Panoutsopoulou, Oluf Pedersen, Craig E Pennell, Christine Power, Sijmen A Reijneveld, Fernando Rivadeneira, Angela Simpson, Peter D Sly, Jakob Stokholm, Kook K Teo, Elisabeth Thiering, Nicholas J Timpson, André G Uitterlinden, Catharina EM van Beijsterveldt, Barbera DC van Schaik, Marc Vaudel, Elvira Verduci, Rebecca K Vinding, Mandy Vogel, Eleftheria Zeggini, Sylvain Sebert, Mads V Lind, Christopher D Brown, Loreto Santa-Marina, Eva Reischl, Christine Frithioff-Bøjsøe, David Meyre, Eleanor Wheeler, Ken Ong, Ellen A Nohr, Tanja GM Vrijkotte, Gerard H Koppelman, Robert Plomin, Pål R Njølstad, George D Dedoussis, Philippe Froguel, Thorkild IA Sørensen, Bo Jacobsson, Rachel M Freathy, Babette S Zemel, Olli Raitakari, Martine Vrijheid, Bjarke Feenstra, Leo-Pekka Lyytikäinen, Harold Snieder, Holger Kirsten, Patrick G Holt, Joachim Heinrich, Elisabeth Widén, Jordi Sunyer, Dorret I Boomsma, Marjo-Riitta Järvelin, Antje Körner, George Davey Smith, Jens-Christian Holm, Mustafa Atalay, Clare Murray, Hans Bisgaard, Mark I McCarthy, Early Growth Genetics Consortium, Vincent WV Jaddoe, Struan FA Grant, Janine F Felix
Nov 12, 2020
The genetic background of childhood body mass index (BMI), and the extent to which the well-known associations of childhood BMI with adult diseases are explained by shared genetic factors, are largely unknown. We performed a...
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Genome-wide associations for birth weight and correlations with adult disease
M Horikoshi, RN Beaumont, FR Day, NM Warrington, MN Kooijman, J Fernandez-Tajes, B Feenstra, NR van Zuydam, KJ Gaulton, N Grarup, JP Bradfield, DP Strachan, R Li-Gao, TS Ahluwalia, E Kreiner, R Rueedi, L-P Lyytikäinen, DL Cousminer, Y Wu, E Thiering, CA Wang, CT Have, J-J Hottenga, N Vilor-Tejedor, PK Joshi, ETH Boh, I Ntalla, N Pitkänen, A Mahajan, EM van Leeuwen, R Joro, V Lagou, M Nodzenski, LA Diver, KT Zondervan, M Bustamante, P Marques-Vidal, JM Mercader, AJ Bennett, N Rahmioglu, DR Nyholt, RCW Ma, CHT Tam, WH Tam, CHARGE Consortium Hematology Working Group, SK Ganesh, FJA van Rooij, SE Jones, P-R Loh, KS Ruth, MA Tuke, J Tyrrell, AR Wood, H Yaghootkar, DM Scholtens, L Paternoster, I Prokopenko, P Kovacs, M Atalay, SM Willems, K Panoutsopoulou, X Wang, L Carstensen, F Geller, KE Schraut, M Murcia, CEM van Beijsterveldt, G Willemsen, EVR Appel, CE Fonvig, C Trier, CMT Tiesler, M Standl, Z Kutalik, S Bonàs-Guarch, DM Hougaard, F Sánchez, D Torrents, J Waage, MV Hollegaard, HG de Haan, FR Rosendaal, C Medina-Gomez, SM Ring, G Hemani, G McMahon, NR Robertson, CJ Groves, C Langenberg, J Luan, RA Scott, JH Zhao, FD Mentch, SM MacKenzie, RM Reynolds, Early Growth Genetics (EGG) Consortium, WL Lowe, A Tönjes, M Stumvoll, V Lindi, TA Lakka, CM van Duijn, W Kiess, A Körner, TIA Sørensen, H Niinikoski, K Pahkala, OT Raitakari, E Zeggini, GV Dedoussis, Y-Y Teo, S-M Saw, M Melbye, H Campbell, JF Wilson, M Vrijheid, EJCN de Geus, DI Boomsma, HN Kadarmideen, J-C Holm, T Hansen, S Sebert, AT Hattersley, LJ Beilin, JP Newnham, CE Pennell, J Heinrich, LS Adair, JB Borja, KL Mohlke, JG Eriksson, E Widén, M Kähönen, JS Viikari, T Lehtimäki, P Vollenweider, K Bønnelykke, H Bisgaard, DO Mook-Kanamori, A Hofman, F Rivadeneira, AG Uitterlinden, C Pisinger, O Pedersen, C Power, E Hyppönen, NJ Wareham, H Hakonarson, E Davies, BR Walker, VWV Jaddoe, M-R Järvelin, SFA Grant, AA Vaag, DA Lawlor, TM Frayling, GD Smith, AP Morris, KK Ong, JF Felix, NJ Timpson, JRB Perry, DM Evans, MI McCarthy, RM Freathy
Dec 01, 2016
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