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Research on Hybrid Immune Algorithm for Solving the Location-Routing Problem With Simultaneous Pickup and Delivery
Xiaowei Wang
Feb 21, 2022
In the simultaneous pickup and delivery problem, every customer has both delivery demand and pick-up demand, and both demands need to be served simultaneously．Under this condition, a location-routing problem with simultaneous...
Published by: IGI Global Scientific Publishing
Evaluation of drug delivery to intact and porated skin by coherent Raman scattering and fluorescence microscopies
Natalie A. Belsey, Natalie L. Garrett, L. Rodrigo Contreras-Rojas, Adam J. Pickup-Gerlaugh, Gareth J. Price, Julian Moger, Richard H. Guy
Jan 28, 2014
Stimulated Raman scattering microscopy was used to assess the permeation of topically applied drugs and formulation excipients into porcine skin. This chemically selective technique generates high-resolution 3D images, from...
Insulin pump therapy with automated insulin suspension in response to hypoglycemia
Pratik Choudhary, John Shin, Yongyin Wang, Mark L Evans, Peter J Hammond, David Kerr, James Am Shaw, John C Pickup, Stephanie A Amiel
Feb 14, 2020
OBJECTIVE: To evaluate a sensor-augmented insulin pump with a low glucose suspend (LGS) feature that automatically suspends basal insulin delivery for up to 2 h in response to sensor-detected hypoglycemia. RESEARCH DESIGN AND...
Immune dysregulation among students exposed to exam stress and its mitigation by mindfulness training
Lorinda Turner, Julieta Galante, Maris Vainre, Jan Stochl, Géraldine Dufour, Peter B Jones
May 04, 2020
Psychological distress persisting for weeks or more promotes pro-inflammatory immune dysregulation, a risk factor for a range of chronic diseases. We have recently shown that mindfulness training reduces distress among...
Published by: Scientific reports
Immune dysregulation among students exposed to exam stress and its mitigation by mindfulness training
Lorinda Turner, Julieta Galante, Maris Vainre, Jan Stochl, Géraldine Dufour, Peter B Jones
Feb 20, 2020
Psychological distress persisting for weeks or more promotes pro-inflammatory immune dysregulation, a risk factor for a range of chronic diseases. We have recently shown that mindfulness training reduces distress among...
Immune dysregulation among students exposed to exam stress and its mitigation by mindfulness training
Lorinda Turner, Julieta Galante, Maris Vainre, Jan Stochl, Géraldine Dufour, Peter B. Jones
Apr 02, 2021
Abstract: Psychological distress persisting for weeks or more promotes pro-inflammatory immune dysregulation, a risk factor for a range of chronic diseases. We have recently shown that mindfulness training reduces distress among...
Evaluation of drug delivery to intact and porated skin by coherent Raman scattering and fluorescence microscopies
Natalie A. Belsey, Natalie L. Garrett, L. Rodrigo Contreras-Rojas, Adam J. Pickup-Gerlaugh, Gareth J. Price, Julian Moger, Richard H. Guy
Jan 28, 2014
Stimulated Raman scattering microscopy was used to assess the permeation of topically applied drugs and formulation excipients into porcine skin. This chemically selective technique generates high-resolution 3D images, from...
Peripheral Immune Cell Populations Associated with Cognitive Deficits and Negative Symptoms of Treatment-Resistant Schizophrenia.
Emilio Fernandez-Egea, Petra E Vértes, Shaun M Flint, Lorinda Turner, Syed Mustafa, Alex Hatton, Kenneth GC Smith, Paul A Lyons, Edward T Bullmore
Sep 05, 2018
BACKGROUND: Hypothetically, psychotic disorders could be caused or conditioned by immunological mechanisms. If so, one might expect there to be peripheral immune system phenotypes that are measurable in blood cells as biomarkers...
Adult Antipsychotic Agents Biomarkers CD4 Lymphocyte Count Case-Control Studies Clozapine Cognitive Dysfunction Cross-Sectional Studies Dendritic Cells Female Flow Cytometry HLA-DR Antigens Humans Immunologic Memory Killer Cells Natural Lymphocyte Activation Male Middle Aged Receptors Dopamine D3 Schizophrenia T-Lymphocyte Subsets T-Lymphocytes Regulatory Young Adult
The Grizzly, October 7, 2004
Lindsey Fund, Lauren A. Perotti, Tia Larese, Lynn Jusinski, Eden Swick, Chris Curley, Megan Helzner, Dan Devlin, Jade Garcia, Ashley Higgins, Amanda Bryman, Aziz Shaikh, Cecily Macconchie
Jan 01, 0001
Ursinus Students Help in the Fight Against Cancer New Sports Bar Opening Near Campus Sigma Who? Students try to Bring National Fraternity to Campus Did you Watch the Presidential Debates? Spotlight on Alpha Sigma Nu Ursinus...
Ursinus College Collegeville Pennsylvania newspaper cross country field hockey Wismer dining hall Patricia Schroeder Alpha Sigma Nu Sigma Pi Alex's Lemonade Stand Juno's Sports Bar cultural history Higher Education Liberal Studies Social History United States History
Published by: Ursinus College
Raynaud phenomenon and digital ulcers in systemic sclerosis
Michael Hughes, Yannick Allanore, Lorinda Chung, John D. Pauling, Christopher P. Denton, Marco Matucci-Cerinic
Apr 30, 2020
Raynaud phenomenon is a symptom complex caused by impaired digital perfusion and can occur as a primary phenomenon or secondary to a wide range of underlying causes. Raynaud phenomenon occurs in virtually all patients with...
Raynaud phenomenon and digital ulcers in systemic sclerosis
Michael Hughes, Yannick Allanore, Lorinda Chung, John D. Pauling, Christopher P. Denton, Marco Matucci-Cerinic
Apr 30, 2020
Raynaud phenomenon is a symptom complex caused by impaired digital perfusion and can occur as a primary phenomenon or secondary to a wide range of underlying causes. Raynaud phenomenon occurs in virtually all patients with...
A Helicobacter pylori Homolog of Eukaryotic Flotillin Is Involved in Cholesterol Accumulation, Epithelial Cell Responses and Host Colonization.
Melanie L Hutton, Kimberley D'Costa, Amanda E Rossiter, Lin Wang, Lorinda Turner, David L Steer, Seth L Masters, Ben A Croker, Maria Kaparakis-Liaskos, Richard L Ferrero
Feb 07, 2019
The human pathogen Helicobacter pylori acquires cholesterol from membrane raft domains in eukaryotic cells, commonly known as "lipid rafts." Incorporation of this cholesterol into the H. pylori cell membrane allows the bacterium...
CagA Helicobacter pylori bacterial flotillins Cholesterol Lipid rafts membrane raft domains type IV secretion system Animals Antigens Bacterial Bacterial Adhesion Bacterial Proteins Cell Line Cell Membrane Cholesterol Cytokines Epithelial Cells Eukaryotic Cells Female Gene Expression Regulation Bacterial Helicobacter Infections Helicobacter pylori Host-Pathogen Interactions Humans Interleukin-8 Membrane Microdomains Membrane Proteins Mice Mice Inbred C57BL Mutagenesis Mutation RAW 264.7 Cells Recombinant Proteins Type IV Secretion Systems Virulence
An exact algorithm for the static rebalancing problem arising in bicycle sharing systems
Bicycle sharing systems can significantly reduce traffic, pollution, and the need for parking spaces in city centers. One of the keys to success for a bicycle sharing system is the efficiency of rebalancing operations, where the...
Cluster-Based Cab Recommender System (CBCRS) for Solo Cab Drivers
An efficient cluster-based cab recommender system (CBCRS) provides solo cab drivers with recommendations about the next pickup location having high passenger finding potential at the shortest distance. To recommend the cab...
Published by: IGI Global Scientific Publishing
An exact algorithm for the static rebalancing problem arising in bicycle sharing systems
Bicycle sharing systems can significantly reduce traffic, pollution, and the need for parking spaces in city centers. One of the keys to success for a bicycle sharing system is the efficiency of rebalancing operations, where the...
RAISE study protocol
Laura Moreno-López, Samantha N Sallie, Konstantinos Ioannidis, Muzaffer Kaser, Katja Schueler, Adrian Dahl Askelund, Lorinda Turner, Anne-Laura van Harmelen, RAISE Consortium
Jan 22, 2021
INTRODUCTION: This paper describes the protocol for an ongoing project funded by the Royal Society, the Resilience After Individual Stress Exposure (RAISE) study; which aims to examine the factors and mechanisms that facilitate...
Dysconnectivity of a brain functional network was associated with blood inflammatory markers in depression.
Athina R Aruldass, Manfred G Kitzbichler, Sarah E Morgan, Sol Lim, Mary-Ellen Lynall, Lorinda Turner, Petra Vertes, Wellcome Trust Consortium for Neuroimmunology of Mood Disorders and Alzheimer’s Disease (NIMA), Jonathan Cavanagh, Phil Cowen, Carmine M Pariante, Neil A Harrison, Edward T Bullmore
Aug 23, 2021
OBJECTIVE: There is increasing evidence for a subgroup of major depressive disorder (MDD) associated with heightened peripheral blood inflammatory markers. In this study, we aimed to understand the mechanistic brain-immune axis...
Peripheral Blood Cell-Stratified Subgroups of Inflamed Depression.
Mary-Ellen Lynall, Lorinda Turner, Junaid Bhatti, Jonathan Cavanagh, Peter de Boer, Valeria Mondelli, Declan Jones, Wayne C Drevets, Philip Cowen, Neil A Harrison, Carmine M Pariante, Linda Pointon, Menna R Clatworthy, Edward Bullmore, Neuroimmunology of Mood Disorders and Alzheimer’s Disease (NIMA) Consortium
Dec 11, 2019
The static bicycle relocation problem with demand intervals
This study introduces the Static Bicycle Relocation Problem with Demand Intervals (SBRP-DI), a variant of the One Commodity Pickup and Delivery Traveling Salesman Problem (1-PDTSP). In the SBRP-DI, the stations are required to...
The Ursinus Weekly, May 7, 1956
Lawrence C. Foard, Marguerite Struth, Karl Herwig, William H. Rheiner, David Hudnut, Thomas M. McCabe, Bruce MacGregor
Jan 01, 0001
College Library vandalized; Files, matting are damaged Y cabinet meets; New chairmen and leaders named NSA conference report MSGA officers to be elected in Wednesday voting WAA banquet to be held on May 8 Men's government...
Ursinus College Collegeville Pennsylvania newspaper LIBRARY vandalism YMCA YWCA National Student Assembly student government Women's Athletic Association Curtain Club Demas Sigma Rho Lambda May Day pageant College band Meistersingers Delta Pi Sigma Navy Donald G. Baker rules and customs track team softball tennis Skip Ruth Intramural Sports baseball Beta Sigma Lambda cultural history Higher Education Liberal Studies Social History United States History
Published by: Ursinus College
The static bicycle relocation problem with demand intervals
This study introduces the Static Bicycle Relocation Problem with Demand Intervals (SBRP-DI), a variant of the One Commodity Pickup and Delivery Traveling Salesman Problem (1-PDTSP). In the SBRP-DI, the stations are required to...
Dual-Channel Supply Chain Coordination With BOPS and a Revenue-Sharing Contract
Hui Li
Jan 01, 2022
The omni-channel strategies buy-online-pickup-in-store (BOPS) is used to cater to customers who want a consistent service experience in different channels. In this paper, the author thinks of BOPS as an effective strategy for...
Published by: IGI Global Scientific Publishing
Whole-blood expression of inflammasome- and glucocorticoid-related mRNAs correctly separates treatment-resistant depressed patients from drug-free and responsive patients in the BIODEP study
Annamaria Cattaneo, Clarissa Ferrari, Lorinda Turner, Nicole Mariani, Daniela Enache, Caitlin Hastings, Melisa Kose, Giulia Lombardo, Anna P. McLaughlin, Maria A. Nettis, Naghmeh Nikkheslat, Luca Sforzini, Courtney Worrell, Zuzanna Zajkowska, Nadia Cattane, Nicola Lopizzo, Monica Mazzelli, Linda Pointon, Philip J. Cowen, Jonathan Cavanagh, Neil A. Harrison, Peter de Boer, Declan Jones, Wayne C. Drevets, Valeria Mondelli, Edward T. Bullmore, Carmine M. Pariante
Jul 23, 2020
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