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Program for the Stage Production Joan of Lorraine
Curtain Club
Jan 01, 0001
This four-page program details the Curtain Club of Ursinus College's production of Joan of Lorraine, held November 21 and 22, 1958 in Thompson-Gay Gymnasium. It includes information about the directors, cast, production of the...
Maxwell Anderson Curtain Club Ursinus College theater program Thompson-Gay Gymnasium Theatre and Performance Studies Theatre History
Published by: Ursinus College
Linking chondrocyte and synovial transcriptional profile to clinical phenotype in osteoarthritis
Widespread epigenomic, transcriptomic and proteomic differences between hip osteophytic and articular chondrocytes in osteoarthritis.
Julia Steinberg, Roger A Brooks, Lorraine Southam, Sahir Bhatnagar, Theodoros I Roumeliotis, Konstantinos Hatzikotoulas, Eleni Zengini, J Mark Wilkinson, Jyoti S Choudhary, Andrew W McCaskie, Eleftheria Zeggini
Sep 05, 2018
Linking chondrocyte and synovial transcriptional profile to clinical phenotype in osteoarthritis.
Julia Steinberg, Lorraine Southam, Andreas Fontalis, Matthew J Clark, Raveen L Jayasuriya, Diane Swift, Karan M Shah, Roger A Brooks, Andrew W McCaskie, Jeremy Mark Wilkinson, Eleftheria Zeggini
May 03, 2021
OBJECTIVES: To determine how gene expression profiles in osteoarthritis joint tissues relate to patient phenotypes and whether molecular subtypes can be reproducibly captured by a molecular classification algorithm. METHODS: We...
Whole-genome sequencing analysis of the cardiometabolic proteome.
Arthur Gilly, Young-Chan Park, Grace Png, Andrei Barysenka, Iris Fischer, Thea Bjørnland, Lorraine Southam, Daniel Suveges, Sonja Neumeyer, N William Rayner, Emmanouil Tsafantakis, Maria Karaleftheri, George Dedoussis, Eleftheria Zeggini
Dec 10, 2020
The human proteome is a crucial intermediate between complex diseases and their genetic and environmental components, and an important source of drug development targets and biomarkers. Here, we comprehensively assess the...
A molecular quantitative trait locus map for osteoarthritis
Julia Steinberg, Lorraine Southam, Theodoros I. Roumeliotis, Matthew J. Clark, Raveen L. Jayasuriya, Diane Swift, Karan M. Shah, Natalie C. Butterfield, Roger A. Brooks, Andrew W. McCaskie, J. H. Duncan Bassett, Graham R. Williams, Jyoti S. Choudhary, J. Mark Wilkinson, Eleftheria Zeggini
Feb 26, 2021
Using ancestry-informative markers to identify fine structure across 15 populations of European origin.
Laura M Huckins, Vesna Boraska, Christopher S Franklin, James AB Floyd, Lorraine Southam, GCAN, WTCCC3, Patrick F Sullivan, Cynthia M Bulik, David A Collier, Chris Tyler-Smith, Eleftheria Zeggini, Ioanna Tachmazidou, GCAN, WTCCC3
Nov 17, 2017
The Wellcome Trust Case Control Consortium 3 anorexia nervosa genome-wide association scan includes 2907 cases from 15 different populations of European origin genotyped on the Illumina 670K chip. We compared methods for...
A molecular quantitative trait locus map for osteoarthritis
Julia Steinberg, Lorraine Southam, Theodoros I. Roumeliotis, Matthew J. Clark, Raveen L. Jayasuriya, Diane Swift, Karan M. Shah, Natalie C. Butterfield, Roger A. Brooks, Andrew W. McCaskie, J. H. Duncan Bassett, Graham R. Williams, Jyoti S. Choudhary, J. Mark Wilkinson, Eleftheria Zeggini
Apr 13, 2021
Cohort-wide deep whole genome sequencing and the allelic architecture of complex traits.
Arthur Gilly, Daniel Suveges, Karoline Kuchenbaecker, Martin Pollard, Lorraine Southam, Konstantinos Hatzikotoulas, Aliki-Eleni Farmaki, Thea Bjornland, Ryan Waples, Emil VR Appel, Elisabetta Casalone, Giorgio Melloni, Britt Kilian, Nigel W Rayner, Ioanna Ntalla, Kousik Kundu, Klaudia Walter, John Danesh, Adam Butterworth, Inês Barroso, Emmanouil Tsafantakis, George Dedoussis, Ida Moltke, Eleftheria Zeggini
Feb 07, 2019
The role of rare variants in complex traits remains uncharted. Here, we conduct deep whole genome sequencing of 1457 individuals from an isolated population, and test for rare variant burdens across six cardiometabolic traits....
Enrichment of low-frequency functional variants revealed by whole-genome sequencing of multiple isolated European populations.
Yali Xue, Massimo Mezzavilla, Marc Haber, Shane McCarthy, Yuan Chen, Vagheesh Narasimhan, Arthur Gilly, Qasim Ayub, Vincenza Colonna, Lorraine Southam, Christopher Finan, Andrea Massaia, Himanshu Chheda, Priit Palta, Graham Ritchie, Jennifer Asimit, George Dedoussis, Paolo Gasparini, Aarno Palotie, Samuli Ripatti, Nicole Soranzo, Daniela Toniolo, James F Wilson, Richard Durbin, Chris Tyler-Smith, Eleftheria Zeggini
Aug 15, 2018
The genetic features of isolated populations can boost power in complex-trait association studies, and an in-depth understanding of how their genetic variation has been shaped by their demographic history can help leverage these...
A molecular quantitative trait locus map for osteoarthritis.
Julia Steinberg, Lorraine Southam, Theodoros I Roumeliotis, Matthew J Clark, Raveen L Jayasuriya, Diane Swift, Karan M Shah, Natalie C Butterfield, Roger A Brooks, Andrew W McCaskie, JH Duncan Bassett, Graham R Williams, Jyoti S Choudhary, J Mark Wilkinson, Eleftheria Zeggini
Mar 04, 2021
Osteoarthritis causes pain and functional disability for over 500 million people worldwide. To develop disease-stratifying tools and modifying therapies, we need a better understanding of the molecular basis of the disease in...
Insights into the genetic architecture of haematological traits from deep phenotyping and whole-genome sequencing for two Mediterranean isolated populations.
Karoline Kuchenbaecker, Arthur Gilly, Daniel Suveges, Lorraine Southam, Olga Giannakopoulou, Britt Kilian, Emmanouil Tsafantakis, Maria Karaleftheri, Aliki-Eleni Farmaki, Deepti Gurdasani, Kousik Kundu, Manjinder S Sandhu, John Danesh, Adam Butterworth, Inês Barroso, George Dedoussis, Eleftheria Zeggini
Jan 28, 2022
Insights into the genetic architecture of haematological traits from deep phenotyping and whole-genome sequencing for two Mediterranean isolated populations.
Karoline Kuchenbaecker, Arthur Gilly, Daniel Suveges, Lorraine Southam, Olga Giannakopoulou, Britt Kilian, Emmanouil Tsafantakis, Maria Karaleftheri, Aliki-Eleni Farmaki, Deepti Gurdasani, Kousik Kundu, Manjinder S Sandhu, John Danesh, Adam Butterworth, Inês Barroso, George Dedoussis, Eleftheria Zeggini
Sep 17, 2022
Genome-wide analyses using UK Biobank data provide insights into the genetic architecture of osteoarthritis.
Eleni Zengini, Konstantinos Hatzikotoulas, Ioanna Tachmazidou, Julia Steinberg, Fernando P Hartwig, Lorraine Southam, Sophie Hackinger, Cindy G Boer, Unnur Styrkarsdottir, Arthur Gilly, Daniel Suveges, Britt Killian, Thorvaldur Ingvarsson, Helgi Jonsson, George C Babis, Andrew McCaskie, Andre G Uitterlinden, Joyce BJ van Meurs, Unnur Thorsteinsdottir, Kari Stefansson, George Davey Smith, Jeremy M Wilkinson, Eleftheria Zeggini
May 03, 2018
Osteoarthritis is a common complex disease imposing a large public-health burden. Here, we performed a genome-wide association study for osteoarthritis, using data across 16.5 million variants from the UK Biobank resource. After...
Kwanzaa Promises to Be Educational, Entertaining
Winthrop University
Jan 01, 0001
Lorraine D. Acker of UNC-Charlotte will speak at Winthrop's Kwanzaa celebration Nov. 28. The program will include music and dance performances.
Published by: Winthrop University
The Ursinus Weekly, November 13, 1922
F. Nelsen Schlegel
Jan 01, 0001
Fighting red and black team triumphs over PMC eleven Dr. Stibitz speaks at chapel service Interscholastic Debating League meets at Ursinus Old timers discuss football situation Audience lavish in applause of recital ...
Ursinus College Collegeville Pennsylvania newspaper debate team George Stibitz field hockey Football Bruce Beach YMCA YWCA Schaff literary society Zwinglian literary society cultural history Higher Education Liberal Studies Social History United States History
Published by: Ursinus College
The transferability of lipid loci across African, Asian and European cohorts.
Karoline Kuchenbaecker, Nikita Telkar, Theresa Reiker, Robin G Walters, Kuang Lin, Anders Eriksson, Deepti Gurdasani, Arthur Gilly, Lorraine Southam, Emmanouil Tsafantakis, Maria Karaleftheri, Janet Seeley, Anatoli Kamali, Gershim Asiki, Iona Y Millwood, Michael Holmes, Huaidong Du, Yu Guo, Meena Kumari, George Dedoussis, Liming Li, Zhengming Chen, Manjinder S Sandhu, Eleftheria Zeggini, Understanding Society Scientific Group
Oct 29, 2019
Most genome-wide association studies are based on samples of European descent. We assess whether the genetic determinants of blood lipids, a major cardiovascular risk factor, are shared across populations. Genetic correlations...
Arts Council of York County Presents Winthrop Jazz Guitar Ensemble on April 24
Winthrop University
Jan 01, 0001
The students will be accompanied by bassist Andy Preston, who is also orchestra director for the Lexington 2 School District and the S.C. Philharmonic. All musicians are guitar majors in the Department of Music who will show...
Published by: Winthrop University
Language-related domain-specific and domain-general systems in the human brain.
While a long history of neuropsychological research places language function within a primarily left-lateralized frontotemporal system, recent neuroimaging work has extended this language network to include a number of regions...
The Ursinus Weekly, October 13, 1958
Men's student government publishes new rules booklet Dr. C. N. Parkinson enthralls Forum audience Oct. 7 Folk singer to appear at museum this Saturday Dinner held for frosh women in Paisley, Oct. 7 "Joan of Lorraine" picked...
Ursinus College Collegeville Pennsylvania newspaper student government rules and customs Belifiore Dillio Curtain Club C. Northcote Parkinson Richard Dyer-Bennet YMCA YWCA Alpha Phi Omega Lantern Soccer cross country Football Business Administration Club student government PSEA Varsity Club Beardwood Chemical Society cultural history Higher Education Liberal Studies Social History United States History
Published by: Ursinus College
Net Zero
Societal transformation, investment, and behaviour change over the next decade will be required if we are to address the climate and ecological emergency effectively. Yet, to date, the focus of climate policy globally has been...
Habit and climate change
Many climate-relevant behaviours are habitual. Habits are memory-based propensities to respond automatically to specific cues, acquired by repetition of behaviours in stable contexts. Socio-cognitive models are widely used to...
The Transferability of Lipid-Associated Loci Across African, Asian and European Cohorts
Nikita Telkar, Theresa Reiker, Robin G Walters, Kuang Lin, Anders Eriksson, Deepti Gurdasani, Arthur Gilly, Lorraine Southam, Emmanouil Tsafantakis, Maria Karaleftheri, Janet Seeley, Anatoli Kamali, Gershim Asiki, Iona Y Millwood, Michael Holmes, Huaidong Du, Yu Guo, Meena Kumari, George Dedoussis, Liming Li, Zhengming Chen, Manjinder S Sandhu, Eleftheria Zeggini, Karoline Kuchenbaecker, Understanding Soc Sci Grp
Sep 23, 2020
Abstract: Most genome-wide association studies are based on samples of European descent. We assess whether the genetic determinants of blood lipids, a major cardiovascular risk factor, are shared across populations. Genetic...
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