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Arnoldi decomposition, GMRES, and preconditioning for linear discrete ill-posed problems
GMRES is one of the most popular iterative methods for the solution of large linear systems of equations that arise from the discretization of linear well-posed problems, such as boundary value problems for elliptic partial...
Arnoldi decomposition, GMRES, and preconditioning for linear discrete ill-posed problems
GMRES is one of the most popular iterative methods for the solution of large linear systems of equations that arise from the discretization of linear well-posed problems, such as boundary value problems for elliptic partial...
Plant Vasculature
To introduce pits into a cell wall, plants depolymerize cortical microtubules, which prevents subsequent secondary cell wall thickening. A newly identified protein tethers microtubules to the plasma membrane and contains this...
Achieving functional neuronal dendrite structure through sequential stochastic growth and retraction.
André Ferreira Castro, Lothar Baltruschat, Tomke Stürner, Amirhoushang Bahrami, Peter Jedlicka, Gaia Tavosanis, Hermann Cuntz
Feb 08, 2021
Class I ventral posterior dendritic arborisation (c1vpda) proprioceptive sensory neurons respond to contractions in the Drosophila larval body wall during crawling. Their dendritic branches run along the direction of...
D. melanogaster computer model dendrite function dendrite growth dendrite retraction developmental biology Mechanotransduction neuroscience self-organisation Animals Animals Genetically Modified Dendrites Drosophila Drosophila Proteins Gene Expression Regulation Developmental Green Fluorescent Proteins Morphogenesis Sensory Receptor Cells
Achieving functional neuronal dendrite structure through sequential stochastic growth and retraction
André Ferreira Castro, Lothar Baltruschat, Tomke Stürner, Amirhoushang Bahrami, Peter Jedlicka, Gaia Tavosanis, Hermann Cuntz
Jan 27, 2021
Class I ventral posterior dendritic arborisation (c1vpda) proprioceptive sensory neurons respond to contractions in the Drosophila larval body wall during crawling. Their dendritic branches run along the direction of...
Ionic liquid facilitated melting of the metal-organic framework ZIF-8.
Vahid Nozari, Courtney Calahoo, Joshua M Tuffnell, David A Keen, Thomas D Bennett, Lothar Wondraczek
Oct 31, 2021
Hybrid glasses from melt-quenched metal-organic frameworks (MOFs) have been emerging as a new class of materials, which combine the functional properties of crystalline MOFs with the processability of glasses. However, only a...
Analysis of mutations in pncA reveals non-overlapping patterns among various lineages of Mycobacterium tuberculosis
Abstract Pyrazinamide (PZA) is an important first-line anti-tuberculosis drug, resistance to which occurs primarily due to mutations in pncA ...
Ramani Baddam, Narender Kumar, Lothar H Wieler, Aditya Kumar Lankapalli, Niyaz Ahmed, Sharon J Peacock, Torsten Semmler
May 30, 2018
Ionic liquid facilitated melting of the metal-organic framework ZIF-8
Vahid Nozari, Courtney Calahoo, Joshua M. Tuffnell, David A. Keen, Thomas D. Bennett, Lothar Wondraczek
Oct 01, 2021
Abstract: Hybrid glasses from melt-quenched metal-organic frameworks (MOFs) have been emerging as a new class of materials, which combine the functional properties of crystalline MOFs with the processability of glasses. However...
Analysis of mutations in pncA reveals non-overlapping patterns among various lineages of Mycobacterium tuberculosis.
Ramani Baddam, Narender Kumar, Lothar H Wieler, Aditya Kumar Lankapalli, Niyaz Ahmed, Sharon J Peacock, Torsten Semmler
Sep 26, 2018
Pyrazinamide (PZA) is an important first-line anti-tuberculosis drug, resistance to which occurs primarily due to mutations in pncA (Rv2043c) that encodes the pyrazinamidase enzyme responsible for conversion of pro-drug PZA into...
Materials Formed by Combining Inorganic Glasses and Metal-Organic Frameworks.
Ashleigh M Chester, Celia Castillo-Blas, Lothar Wondraczek, David A Keen, Thomas D Bennett
May 25, 2022
Here, we propose the combination of glassy or crystalline metal-organic frameworks (MOFs) with inorganic glasses to create novel hybrid composites and blends.The motivation behind this new composite approach is to improve the...
The reactivity of an inorganic glass melt with ZIF-8.
Louis Longley, Courtney Calahoo, Thomas JF Southern, Rachel C Evans, Lothar Wondraczek, Thomas D Bennett
Feb 10, 2021
The thermal behaviour of ZIF-8, Zn(meIm)2 in the presence of a sodium fluoroaluminophosphate glass melt was probed through differential scanning calorimetry and thermogravimetric analysis. The structural integrity of ZIF-8 was...
Sodium Ion Conductivity in Superionic IL-Impregnated Metal-Organic Frameworks
Vahid Nozari, Courtney Calahoo, Joshua M Tuffnell, Philipp Adelhelm, Katrin Wondraczek, Siân E Dutton, Thomas D Bennett, Lothar Wondraczek
Mar 29, 2020
Metal-organic frameworks (MOFs) are intriguing host materials in composite electrolytes due to their ability for tailoring host-guest interactions by chemical tuning of the MOF backbone. Here, we introduce particularly high...
Published by: Scientific reports
Sodium Ion Conductivity in Superionic IL-Impregnated Metal-Organic Frameworks
Vahid Nozari, Courtney Calahoo, Joshua M Tuffnell, Philipp Adelhelm, Katrin Wondraczek, Siân E Dutton, Thomas D Bennett, Lothar Wondraczek
Apr 27, 2020
Metal-organic frameworks (MOFs) are intriguing host materials in composite electrolytes due to their ability for tailoring host-guest interactions by chemical tuning of the MOF backbone. Here, we introduce particularly high...
Sodium Ion Conductivity in Superionic IL-Impregnated Metal-Organic Frameworks
Vahid Nozari, Courtney Calahoo, Joshua M. Tuffnell, Philipp Adelhelm, Katrin Wondraczek, Siân E. Dutton, Thomas D. Bennett, Lothar Wondraczek
Feb 25, 2021
Abstract: Metal-organic frameworks (MOFs) are intriguing host materials in composite electrolytes due to their ability for tailoring host-guest interactions by chemical tuning of the MOF backbone. Here, we introduce particularly...
Metal-organic framework and inorganic glass composites
Louis Longley, Courtney Calahoo, René Limbach, Yang Xia, Joshua M. Tuffnell, Adam F. Sapnik, Michael F. Thorne, Dean S. Keeble, David A. Keen, Lothar Wondraczek, Thomas D. Bennett
Nov 16, 2020
Abstract: Metal-organic framework (MOF) glasses have become a subject of interest as a distinct category of melt quenched glass, and have potential applications in areas such as ion transport and sensing. In this paper we show...
Gold nanoparticles functionalised with fast water exchanging Gd3+ chelates
No Association Between Vitamin D Status and Risk of Barrett's Esophagus or Esophageal Adenocarcinoma
Jing Dong, Puya Gharahkhani, Wong-Ho Chow, Marilie D Gammon, Geoffrey Liu, Carlos Caldas, Anna H Wu, Weimin Ye, Lynn Onstad, Lesley A Anderson, Leslie Bernstein, Paul D Pharoah, Harvey A Risch, Douglas A Corley, Rebecca C Fitzgerald, Stomach and Esophageal Cancer Study Consortium, Prasad G Iyer, Brian J Reid, Jesper Lagergren, Nicholas J Shaheen, Thomas L Vaughan, Stuart MacGregor, Sharon Love, Claire Palles, Ian Tomlinson, Ines Gockel, Andrea May, Christian Gerges, Mario Anders, Anne C Böhmer, Jessica Becker, Nicole Kreuser, Rene Thieme, Tania Noder, Marino Venerito, Lothar Veits, Thomas Schmidt, Claudia Schmidt, Jakob R Izbicki, Arnulf H Hölscher, Hauke Lang, Dietmar Lorenz, Brigitte Schumacher, Rupert Mayershofer, Yogesh Vashist, Katja Ott, Michael Vieth, Josef Weismüller, Markus M Nöthen, Susanne Moebus, Michael Knapp, Wilbert HM Peters, Horst Neuhaus, Thomas Rösch, Christian Ell, Janusz Jankowski, Johannes Schumacher, Rachel E Neale, David C Whiteman, Aaron P Thrift
Nov 01, 2019
BACKGROUND & AIMS: Epidemiology studies of circulating concentrations of 25 hydroxy vitamin D (25(OH)D) and risk of esophageal adenocarcinoma (EAC) have produced conflicting results. We conducted a Mendelian randomization study...
Genome-wide association studies in oesophageal adenocarcinoma and Barrett's oesophagus
Puya Gharahkhani, Rebecca C Fitzgerald, Thomas L Vaughan, Claire Palles, Ines Gockel, Ian Tomlinson, Matthew F Buas, Andrea May, Christian Gerges, Mario Anders, Jessica Becker, Nicole Kreuser, Tania Noder, Marino Venerito, Lothar Veits, Thomas Schmidt, Hendrik Manner, Claudia Schmidt, Timo Hess, Anne C Böhmer, Jakob R Izbicki, Arnulf H Hölscher, Hauke Lang, Dietmar Lorenz, Brigitte Schumacher, Andreas Hackelsberger, Rupert Mayershofer, Oliver Pech, Yogesh Vashist, Katja Ott, Michael Vieth, Josef Weismüller, Markus M Nöthen, Barrett's and Esophageal Adenocarcinoma Consortium (BEACON), Esophageal Adenocarcinoma GenEtics Consortium (EAGLE), Wellcome Trust Case Control Consortium 2 (WTCCC2), Stephen Attwood, Hugh Barr, Laura Chegwidden, John de Caestecker, Rebecca Harrison, Sharon B Love, David MacDonald, Paul Moayyedi, Hans Prenen, RG Peter Watson, Prasad G Iyer, Lesley A Anderson, Leslie Bernstein, Wong-Ho Chow, Laura J Hardie, Jesper Lagergren, Geoffrey Liu, Harvey A Risch, Anna H Wu, Weimin Ye, Nigel C Bird, Nicholas J Shaheen, Marilie D Gammon, Douglas A Corley, Carlos Caldas, Susanne Moebus, Michael Knapp, Wilbert HM Peters, Horst Neuhaus, Thomas Rösch, Christian Ell, Stuart MacGregor, Paul Pharoah, David C Whiteman, Janusz Jankowski, Johannes Schumacher
Sep 29, 2018
BACKGROUND: Oesophageal adenocarcinoma represents one of the fastest rising cancers in high-income countries. Barrett's oesophagus is the premalignant precursor of oesophageal adenocarcinoma. However, only a few patients with...
A comprehensive evaluation of interaction between genetic variants and use of menopausal hormone therapy on mammographic density.
Anja Rudolph, Peter A Fasching, Sabine Behrens, Ursula Eilber, Manjeet K Bolla, Qin Wang, Deborah Thompson, Kamila Czene, Judith S Brand, Jingmei Li, Christopher Scott, V Shane Pankratz, Kathleen Brandt, Emily Hallberg, Janet E Olson, Adam Lee, Matthias W Beckmann, Arif B Ekici, Lothar Haeberle, Gertraud Maskarinec, Loic Le Marchand, Fredrick Schumacher, Roger L Milne, Julia A Knight, Carmel Apicella, Melissa C Southey, Miroslav K Kapuscinski, John L Hopper, Irene L Andrulis, Graham G Giles, Christopher A Haiman, Kay-Tee Khaw, Robert Luben, Per Hall, Paul DP Pharoah, Fergus J Couch, Douglas F Easton, Isabel dos-Santos-Silva, Celine Vachon, Jenny Chang-Claude
Sep 03, 2015
Joint association of mammographic density adjusted for age and body mass index and polygenic risk score with breast cancer risk
Celine M Vachon, Christopher G Scott, Rulla M Tamimi, Deborah J Thompson, Peter A Fasching, Jennifer Stone, Melissa C Southey, Stacey Winham, Sara Lindström, Jenna Lilyquist, Graham G Giles, Roger L Milne, Robert J Macinnis, Laura Baglietto, Jingmei Li, Kamila Czene, Manjeet K Bolla, Qin Wang, Joe Dennis, Lothar Haeberle, Mikael Eriksson, Peter Kraft, Robert Luben, Nick Wareham, Janet E Olson, Aaron Norman, Eric C Polley, Gertraud Maskarinec, Loic Le Marchand, Christopher A Haiman, John L Hopper, Fergus J Couch, Douglas F Easton, Per Hall, Nilanjan Chatterjee, Montse Garcia-Closas
May 28, 2019
breast cancer risk Breast Density genetic variation polygenic risk score Risk models Adult Aged Algorithms Biomarkers Tumor Body Mass Index Breast Density Breast Neoplasms Case-Control Studies Female Humans Middle Aged Models Biological Multifactorial Inheritance Odds Ratio Polymorphism Single Nucleotide Risk Assessment Risk Factors
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