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Remote versus face-to-face neuropsychological testing for dementia research
Maï-Carmen Requena-Komuro, Jessica Jiang, Lucianne Dobson, Elia Benhamou, Lucy Russell, Rebecca L Bond, Emilie V Brotherhood, Caroline Greaves, Suzie Barker, Jonathan D Rohrer, Sebastian J Crutch, Jason D Warren, Chris Jd Hardy
Jan 04, 2023
OBJECTIVES: We explored whether adapting neuropsychological tests for online administration during the COVID-19 pandemic was feasible for dementia research. DESIGN: We used a longitudinal design for healthy controls, who...
Remote versus face-to-face neuropsychological testing for dementia research
Alzheimer's disease
OBJECTIVE: Peripheral protein biomarkers of Alzheimer's disease (AD) may help identify novel treatment avenues by allowing early diagnosis, recruitment to clinical trials, and treatment initiation. The purpose of this review was...
1109 Neurosciences Biomedical Clinical Medicine and Science aging Neurosciences Dementia Neurodegenerative Alzheimer's Disease including Alzheimer's Disease Related Dementias (AD/ADRD) Alzheimer's Disease Brain Disorders Acquired Cognitive Impairment Neurological 4.1 Discovery and preclinical testing of markers and technologies
Prospective clinical trial of masitinib mesylate treatment for advanced stage III and IV canine malignant melanoma.
OBJECTIVE: To investigate efficacy of masitinib mesylate for the treatment of advanced malignant melanoma in dogs. MATERIALS AND METHODS: Prospective clinical trial on 17 dogs with stage III and IV malignant melanoma (two...
A Cell- and Tissue-Specific Weakness of the Protein Homeostasis System Underlies Brain Vulnerability to Protein Aggregation.
The phenomenon of protein misfolding and aggregation is associated with a wide range of neurodegenerative conditions that cause progressive loss of function in specific regions of the human brain. To understand the causes of the...
A Cell- and Tissue-Specific Weakness of the Protein Homeostasis System Underlies Brain Vulnerability to Protein Aggregation.
The phenomenon of protein misfolding and aggregation is associated with a wide range of neurodegenerative conditions that cause progressive loss of function in specific regions of the human brain. To understand the causes of the...
Published by: iScience
Clinical response and survival time of cats with carcinoma of the nasal cavity treated with palliative coarse fractionated radiotherapy.
OBJECTIVES: Carcinoma is the second most common tumour of the nasal cavity in cats. Few studies assessing the response and survival of cats with carcinoma of the nasal cavity treated with palliative coarse fractionated...
The future of radiotherapy in small animals - should the fractions be coarse or fine?
Radiation therapy has been used to treat animal cancers for more than 100 years. Clinical experiences and experimental results have been widely published and provide a basis for the recognition of radiation therapy as an...
Exploring the Dynamics of Base-Excited Structures Impacting a Rigid Stop
This paper explores the nonlinear dynamics of a multidegree of freedom (MDoF) structure impacting a rigid stop. The contact mechanics is simplified by continuous sigmoid function idealisation of a lossless spring. By introducing...
Photodynamic therapy and diagnosis
Photodynamic therapy (PDT) is an evolving method of treating superficial tumours that is non-invasive and carries minimal risk of toxicity. It combines tumour-selective photosensitiser dyes, tissue oxygen and targeted...
Exploring the Dynamics of Base-Excited Structures Impacting a Rigid Stop
This paper explores the nonlinear dynamics of a multidegree of freedom (MDoF) structure impacting a rigid stop. The contact mechanics is simplified by continuous sigmoid function idealisation of a lossless spring. By introducing...
The relevance of contact-independent cell-to-cell transfer of TDP-43 and SOD1 in amyotrophic lateral sclerosis.
Identifying mechanisms influencing the emergence and success of innovation within national economies
This paper uses data from recent OECD (OECD Science, technology and industry scoreboard. OECD Publishing, Paris, 2013b) and Cornell University et al. (The global innovation index 2014. World Intellectual Property Organization...
Microfluidic approaches for probing amyloid assembly and behaviour.
The self-assembly of proteins into supramolecular structures and machinery underpins biological activity in living systems. Misassembled, misfolded and aggregated protein structures can, by contrast, have deleterious activity...
Cross-Currents
Isobel Maddison
Nov 05, 2018
When Elizabeth von Arnim's novel 'Introduction to Sally' appeared in 1926, the critical response was divided. Dame Ethel Smyth may have told von Arnim the book was her 'masterpiece' but some were less convinced; the reviewer in...
Climate change modulates the stratospheric volcanic sulfate aerosol lifecycle and radiative forcing from tropical eruptions.
Thomas J Aubry, John Staunton-Sykes, Lauren R Marshall, Jim Haywood, Nathan Luke Abraham, Anja Schmidt
Sep 13, 2021
Explosive volcanic eruptions affect climate, but how climate change affects the stratospheric volcanic sulfate aerosol lifecycle and radiative forcing remains unexplored. We combine an eruptive column model with an...
Published by: Nature Communications
Climate change modulates the stratospheric volcanic sulfate aerosol lifecycle and radiative forcing from tropical eruptions
Thomas J. Aubry, John Staunton-Sykes, Lauren R. Marshall, Jim Haywood, Nathan Luke Abraham, Anja Schmidt
Aug 12, 2021
Abstract: Explosive volcanic eruptions affect climate, but how climate change affects the stratospheric volcanic sulfate aerosol lifecycle and radiative forcing remains unexplored. We combine an eruptive column model with an...
Glycolysis inhibition improves photodynamic therapy response rates for equine sarcoids.
Photodynamic therapy (PDT) holds great promise in treating veterinary and human dermatological neoplasms, including equine sarcoids, but is currently hindered by the amount of photosensitiser and light that can be delivered to...
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