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Stable antibiotic resistance and rapid human adaptation in livestock-associated MRSA
Lucy Weinert
Jul 28, 2022
Stable antibiotic resistance and rapid human adaptation in livestock-associated MRSA
Lucy Weinert
Jun 29, 2022
Why Might Bacterial Pathogens Have Small Genomes?
Bacteria that cause serious disease often have smaller genomes, and fewer genes, than their nonpathogenic, or less pathogenic relatives. Here, we review evidence for the generality of this association, and summarise the various...
Highway to Hell? Images of the American Road in Kelly Reichardt's<i>Old Joy</i>,<i>Wendy and Lucy</i>, and<i>Meek's Cutoff</i>
This article examines representations of the road in the work of independent Florida-born film director Kelly Reichardt. Reading Reichardt's so-called Oregon trilogy,Old...
DIARMUID HESTER
Dec 10, 2018
The Evolutionary Genomics of Host Specificity in Staphylococcus aureus.
Staphylococcus aureus is an important human bacterial pathogen that has a cosmopolitan host range, including livestock, companion and wild animal species. Genomic and epidemiological studies show that S. aureus has jumped...
Bacteria Emerging Infectious Diseases host adaptation host switch mobile genetic element whole-genome sequencing Animals Bacteria evolution Molecular Genomics Host Adaptation Host Specificity Humans Interspersed Repetitive Sequences Livestock Staphylococcal Infections Staphylococcus aureus whole genome sequencing
Genome Reduction Is Associated with Bacterial Pathogenicity across Different Scales of Temporal and Ecological Divergence.
Gemma GR Murray, Jane Charlesworth, Eric L Miller, Michael J Casey, Catrin T Lloyd, Marcelo Gottschalk, Alexander W Dan Tucker, John J Welch, Lucy A Weinert
Dec 07, 2020
Emerging bacterial pathogens threaten global health and food security, and so it is important to ask whether these transitions to pathogenicity have any common features. We present a systematic study of the claim that...
The Trumpington Cross in context
SJ Lucy
May 11, 2017
An Anglo-Saxon gold and garnet cloisonné pectoral cross from a seventh-century bed burial at Trumpington, Cambridgeshire in 2011 is the fifth such example to be found. Details of the contextual associations of the five crosses...
Rates of vaccine evolution show strong effects of latency
Lucy A Weinert, Daniel P Depledge, Samit Kundu, Anne A Gershon, Richard A Nichols, Francois Balloux, John J Welch, Judith Breuer
May 22, 2015
Update on Streptococcus suis Research and Prevention in the Era of Antimicrobial Restriction
Mariela Segura, Virginia Aragon, Susan L Brockmeier, Connie Gebhart, Astrid de Greeff, Anusak Kerdsin, Mark A O'Dea, Masatoshi Okura, Mariette Saléry, Constance Schultsz, Peter Valentin-Weigand, Lucy A Weinert, Jerry M Wells, Marcelo Gottschalk
Aug 10, 2020
Streptococcus suis is a swine pathogen and a zoonotic agent afflicting people in close contact with infected pigs or pork meat. Sporadic cases of human infections have been reported worldwide. In addition, S. suis outbreaks...
The global distribution and spread of the mobilized colistin resistance gene mcr-1.
Ruobing Wang, Lucy van Dorp, Liam P Shaw, Phelim Bradley, Qi Wang, Xiaojuan Wang, Longyang Jin, Qing Zhang, Yuqing Liu, Adrien Rieux, Thamarai Dorai-Schneiders, Lucy Anne Weinert, Zamin Iqbal, Xavier Didelot, Hui Wang, Francois Balloux
Sep 10, 2018
Colistin represents one of the few available drugs for treating infections caused by carbapenem-resistant Enterobacteriaceae. As such, the recent plasmid-mediated spread of the colistin resistance gene mcr-1 poses a significant...
Americas Anti-Bacterial Agents Asia Carbapenems Colistin DNA Transposable Elements Drug Resistance Multiple Bacterial Enterobacteriaceae Enterobacteriaceae Infections Escherichia coli Proteins Europe evolution Molecular Gene Expression Gene Transfer Horizontal Genome Bacterial Humans Plasmids Population Dynamics
Compliance of participants undergoing a ‘5-2’ intermittent fasting diet and impact on body weight
Background
Intermittent fasting (IF) has grown in popularity as a weight loss tool, where caloric intake is fully/partially restricted on a recurring basis. This study aimed to assess compliance with IF fast-day calorie...
Intermittent fasting (IF) has grown in popularity as a weight loss tool, where caloric intake is fully/partially restricted on a recurring basis. This study aimed to assess compliance with IF fast-day calorie...
Mutation rate dynamics reflect ecological change in an emerging zoonotic pathogen.
Gemma Murray, Andrew Balmer, Josephine Herbert, Nazreen F Hadijirin, Caroline L Kemp, Marta Matuszewska, Sebastian Bruchmann, AS Md Mukarram Hossain, Marcelo Gottschalk, Alexander Tucker, Eric Miller, Lucy Weinert
Nov 24, 2021
Mutation rates vary both within and between bacterial species, and understanding what drives this variation is essential for understanding the evolutionary dynamics of bacterial populations. In this study, we investigate two...
Mutation rate dynamics reflect ecological change in an emerging zoonotic pathogen.
Gemma GR Murray, Andrew J Balmer, Josephine Herbert, Nazreen F Hadijirin, Caroline L Kemp, Marta Matuszewska, Sebastian Bruchmann, AS Md Mukarram Hossain, Marcelo Gottschalk, Alexander W Tucker, Eric Miller, Lucy A Weinert
Jan 07, 2022
Draft Genome Sequences of the Type Strains of Actinobacillus indolicus (46K2C) and Actinobacillus porcinus (NM319), Two NAD-Dependent Bacterial Species Found in the Respiratory Tract of Pigs.
Janine T Bossé, Yanwen Li, Roberto Fernandez Crespo, Øystein Angen, Matthew TG Holden, Lucy A Weinert, Duncan J Maskell, Alexander W Tucker, Brendan W Wren, Andrew N Rycroft, Paul R Langford, BRaDP1T Consortium
Feb 04, 2020
We report here the draft genome sequences of the type strains of Actinobacillus indolicus (46K2C) and Actinobacillus porcinus (NM319). These NAD-dependent bacterial species are frequently found in the upper respiratory tract of...
A shared population of epidemic methicillin-resistant Staphylococcus aureus 15 circulates in humans and companion animals.
Ewan M Harrison, Lucy A Weinert, Matthew TG Holden, John J Welch, Katherine Wilson, Fiona JE Morgan, Simon R Harris, Anette Loeffler, Amanda K Boag, Sharon J Peacock, Gavin K Paterson, Andrew S Waller, Julian Parkhill, Mark A Holmes
Jul 15, 2014
Adaptation Biological Animal Diseases Animals Drug Resistance Bacterial evolution Molecular Genome Bacterial Genome-Wide Association Study Humans Methicillin-Resistant Staphylococcus aureus Multilocus Sequence Typing Phylogeny Polymorphism Single Nucleotide Staphylococcal Infections Virulence Factors
Construction-Worker Father Inspires Future Teacher's Award-Winning Story
Winthrop University
Jan 01, 0001
Quick Facts
Lucy Gardner is a middle level education major from Chester, South Carolina. She was awarded $1,000 and the student fiction prize for her short story, "When the Storm Ends."
Published by: Winthrop University
Extract Clinical Lab Tests From Electronic Hospital Records Through Featured Transformer Model
Natural language, as a rich source of information, has been used as the foundation of the product review, the demographic trend, and the domain specific knowledge bases. To extract entities from texts, the challenge is, free...
Published by: IGI Global Scientific Publishing
"Pathotyping" Multiplex PCR Assay for Haemophilus parasuis
Kate J Howell, Lucy A Weinert, Sarah E Peters, Jinhong Wang, Juan Hernandez-Garcia, Roy R Chaudhuri, Shi-Lu Luan, Øystein Angen, Virginia Aragon, Susanna M Williamson, Paul R Langford, Andrew N Rycroft, Brendan W Wren, Duncan J Maskell, Alexander W Tucker
Aug 22, 2017
Haemophilus parasuis is a diverse bacterial species that is found in the upper respiratory tracts of pigs and can also cause Glässer's disease and pneumonia. A previous pangenome study of H. parasuis identified 48 genes that...
Streptococcus suis contains multiple phase-variable methyltransferases that show a discrete lineage distribution.
John M Atack, Lucy A Weinert, Alexander W Tucker, Asma U Husna, Thomas M Wileman, Nazreen F Hadjirin, Ngo T Hoa, Julian Parkhill, Duncan J Maskell, Patrick J Blackall, Michael P Jennings
Dec 06, 2018
Alleles Animals DNA Methylation DNA Modification Methylases DNA Bacterial Epigenesis Genetic Escherichia coli Gene Expression Regulation Bacterial genetic variation Genome Bacterial Methyltransferases Microsatellite Repeats Oligonucleotides Phenotype Regulon Streptococcal Infections Streptococcus suis Swine
Evaluation of the recombinant proteins RlpB and VacJ as a vaccine for protection against Glaesserella parasuis in pigs
The discovery of Halictivirus resolves the Sinaivirus phylogeny.
Diane Bigot, Anne Dalmon, Bronwen Roy, Chunsheng Hou, Michèle Germain, Manon Romary, Shuai Deng, Qingyun Diao, Lucy A Weinert, James M Cook, Elisabeth A Herniou, Philippe Gayral
Jan 26, 2018
By providing pollination services, bees are among the most important insects, both in ecological and economical terms. Combined next-generation and classical sequencing approaches were applied to discover and study new insect...
Evolutionary loss of inflammasomes in the Carnivora and implications for the carriage of zoonotic infections.
Zsofi Digby, Panagiotis Tourlomousis, James Rooney, Joseph P Boyle, Betsaida Bibo-Verdugo, Robert J Pickering, Steven J Webster, Thomas P Monie, Lee J Hopkins, Nobuhiko Kayagaki, Guy S Salvesen, Soren Warming, Lucy Weinert, Clare E Bryant
Aug 06, 2021
Zoonotic pathogens, such as COVID-19, reside in animal hosts before jumping species to infect humans. The Carnivora, like mink, carry many zoonoses, yet how diversity in host immune genes across species affect pathogen carriage...
Carnivora NLRC4 NLRP3 Caspase 1 caspase 11 caspase 4 inflammasome Animals Carnivora Caspase 1 Caspase 8 Caspases Initiator Cell Death Cell Line evolution Molecular Humans Inflammasomes Interleukin-1beta Lipopolysaccharides MACROPHAGES Mice Mice Inbred C57BL NLR proteins Recombinant Fusion Proteins Recombinant Proteins Salmonella typhi Zoonoses
Whole genome investigation of a divergent clade of the pathogen Streptococcus suis.
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