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Results: 45
Impact of COVID-19 on digital practice in UK paediatric speech and language therapy and implications for the future
BACKGROUND: The COVID-19 pandemic and subsequent measures to reduce transmission risk has led to unprecedented digital transformation across health, education and social care services. This includes UK paediatric speech and...
Keeping your options open
Mélanie A Eckersley-Maslin
Feb 22, 2021
The concept of cellular plasticity is particularly apt in early embryonic development, where there is a tug-of-war between the stability and flexibility of cell identity. This balance is controlled in part through epigenetic...
Dppa2/4 Cell fate Chromatin epigenetic priming epigenetics plasticity Animals Cell Differentiation Cell Lineage Cell Plasticity Chromatin CpG Islands DNA Methylation DNA-Binding Proteins Embryonic Development Epigenesis Genetic Gene Expression Regulation Genome Humans Mice Nuclear Proteins Transcription Factors
Defining the clonal dynamics leading to mouse skin tumour initiation.
Adriana Sánchez-Danés, Edouard Hannezo, Jean-Christophe Larsimont, Mélanie Liagre, Khalil Kass Youssef, Benjamin D Simons, Cédric Blanpain
Aug 16, 2016
Antiviral RNA Interference against Orsay Virus Is neither Systemic nor Transgenerational in Caenorhabditis elegans.
An Alternative STAT Signaling Pathway Acts in Viral Immunity in Caenorhabditis elegans.
Mélanie Tanguy, Louise Véron, Przemyslaw Stempor, Julie Ahringer, Peter Sarkies, Eric A Miska
Apr 11, 2018
Across metazoans, innate immunity is vital in defending organisms against viral infection. In mammals, antiviral innate immunity is orchestrated by interferon signaling, activating the STAT transcription factors downstream of...
Mechanochromic, Structurally Colored, and Edible Hydrogels Prepared from Hydroxypropyl Cellulose and Gelatin
Charles H. Barty‐King, Chun Lam Clement Chan, Richard M. Parker, Mélanie M. Bay, Roberto Vadrucci, Michael De Volder, Silvia Vignolini
Jul 29, 2021
Abstract: Hydroxypropyl cellulose (HPC) is an edible, cost‐effective and widely used derivative of cellulose. Under lyotropic conditions in water, HPC forms a photonic, liquid crystalline mesophase with an exceptional...
RESEARCH ARTICLE RESEARCH ARTICLES cholesteric liquid crystals edible hydrogels hydroxypropyl cellulose mechanochromic materials photonic hydrogels
Published by: Advanced Materials
Decreased expression of miR-29 family associated with autoimmune myasthenia gravis.
Mélanie A Cron, Cloé A Payet, Odessa-Maud Fayet, Solène Maillard, Frédérique Truffault, Elie Fadel, Julien Guihaire, Sonia Berrih-Aknin, Adrian Liston, Rozen Le Panse
Dec 14, 2020
BACKGROUND: Myasthenia gravis (MG) is a rare autoimmune disease mainly mediated by autoantibodies against the acetylcholine receptor (AChR) at the neuromuscular junction. The thymus is the effector organ, and its removal...
BAFF DICER Experimental autoimmune myasthenia gravis Interferon-β Th17 Cells Thymic epithelial cells Thymus MicroRNAs Adolescent Adult Animals Autoantibodies Cells Cultured Female Gene Expression Humans Male Mice Mice Inbred C57BL Mice Knockout MicroRNAs myasthenia gravis myasthenia gravis Autoimmune Experimental Receptors Cholinergic Thymus Gland Young Adult
Mechanochromic, Structurally Colored, and Edible Hydrogels Prepared from Hydroxypropyl Cellulose and Gelatin.
Charles H Barty-King, Chun Lam Clement Chan, Richard M Parker, Mélanie M Bay, Roberto Vadrucci, Michael De Volder, Silvia Vignolini
Jun 23, 2021
MERVL/Zscan4 Network Activation Results in Transient Genome-wide DNA Demethylation of mESCs.
Mélanie A Eckersley-Maslin, Valentine Svensson, Christel Krueger, Thomas M Stubbs, Pascal Giehr, Felix Krueger, Ricardo J Miragaia, Charalampos Kyriakopoulos, Rebecca V Berrens, Inês Milagre, Jörn Walter, Sarah A Teichmann, Wolf Reik
May 16, 2019
Mouse embryonic stem cells are dynamic and heterogeneous. For example, rare cells cycle through a state characterized by decondensed chromatin and expression of transcripts, including the Zscan4 cluster and MERVL endogenous...
DNA Methylation MERVL Zscan4 Chromatin Embryonic Stem Cell Endogenous retrovirus imprint preimplantation reprogramming Animals Cell Cycle Cellular Reprogramming Chromatin DNA Methylation DNA Modification Methylases endogenous retroviruses Epigenesis Genetic Genome Genomic Imprinting Induced Pluripotent Stem Cells Mice Mouse embryonic stem cells Multigene Family RNA Messenger Single-Cell Analysis Transcription Factors Transcriptional Activation Transcriptome
Roll-to-roll fabrication of touch-responsive cellulose photonic laminates.
Hsin-Ling Liang, Mélanie M Bay, Roberto Vadrucci, Charles H Barty-King, Jialong Peng, Jeremy J Baumberg, Michael FL De Volder, Silvia Vignolini
Dec 06, 2018
Hydroxypropyl-cellulose (HPC), a derivative of naturally abundant cellulose, can self-assemble into helical nanostructures that lead to striking colouration from Bragg reflections. The helical periodicity is very sensitive to...
Hyperspectral Imaging of Photonic Cellulose Nanocrystal Films
Bonan Zhu, Villads E Johansen, Gen Kamita, Giulia Guidetti, Mélanie M Bay, Thomas G Parton, Bruno Frka-Petesic, Silvia Vignolini
Oct 08, 2020
Seroprevalence of anti-SARS-CoV-2 IgG at the first epidemic peak in French Guiana, July 2020.
Claude Flamand, Christelle Alves Sarmento, Antoine Enfissi, Sarah Bailly, Emmanuel Beillard, Mélanie Gaillet, Céline Michaud, Véronique Servas, Nathalie Clement, Anaïs Perilhou, Thierry Carage, Didier Musso, Jean-François Carod, Stéphanie Eustache, Céline Tourbillon, Elodie Boizon, Samantha James, Félix Djossou, Henrik Salje, Simon Cauchemez, Dominique Rousset
Dec 22, 2021
Seroprevalence of anti-SARS-CoV-2 IgG at the first epidemic peak in French Guiana, July 2020.
Claude Flamand, Christelle Alves Sarmento, Antoine Enfissi, Sarah Bailly, Emmanuel Beillard, Mélanie Gaillet, Céline Michaud, Véronique Servas, Nathalie Clement, Anaïs Perilhou, Thierry Carage, Didier Musso, Jean-François Carod, Stéphanie Eustache, Céline Tourbillon, Elodie Boizon, Samantha James, Félix Djossou, Henrik Salje, Simon Cauchemez, Dominique Rousset
Jan 07, 2022
Portrait of blood-derived extracellular vesicles in patients with Parkinson's disease.
Jérôme Lamontagne-Proulx, Isabelle St-Amour, Richard Labib, Jérémie Pilon, Hélèna L Denis, Nathalie Cloutier, Florence Roux-Dalvai, Antony T Vincent, Sarah L Mason, Caroline Williams-Gray, Anne-Claire Duchez, Arnaud Droit, Steve Lacroix, Nicolas Dupré, Mélanie Langlois, Sylvain Chouinard, Michel Panisset, Roger A Barker, Eric Boilard, Francesca Cicchetti
Dec 20, 2018
The production of extracellular vesicles (EV) is a ubiquitous feature of eukaryotic cells but pathological events can affect their formation and constituents. We sought to characterize the nature, profile and protein signature...
Nutritional quality of food as represented by the FSAm-NPS nutrient profiling system underlying the Nutri-Score label and cancer risk in Europe
Mélanie Deschasaux, Inge Huybrechts, Neil Murphy, Chantal Julia, Serge Hercberg, Bernard Srour, Emmanuelle Kesse-Guyot, Paule Latino-Martel, Carine Biessy, Corinne Casagrande, Mazda Jenab, Heather Ward, Elisabete Weiderpass, Christina C Dahm, Kim Overvad, Cecilie Kyrø, Anja Olsen, Aurélie Affret, Marie-Christine Boutron-Ruault, Yahya Mahamat-Saleh, Rudolf Kaaks, Tilman Kühn, Heiner Boeing, Lukas Schwingshackl, Christina Bamia, Eleni Peppa, Antonia Trichopoulou, Giovanna Masala, Vittorio Krogh, Salvatore Panico, Rosario Tumino, Carlotta Sacerdote, Bas Bueno-de-Mesquita, Petra H Peeters, Anette Hjartåker, Charlotta Rylander, Guri Skeie, J Ramón Quirós, Paula Jakszyn, Elena Salamanca-Fernández, José María Huerta, Eva Ardanaz, Pilar Amiano, Ulrika Ericson, Emily Sonestedt, Ena Huseinovic, Ingegerd Johansson, Kay-Tee Khaw, Nick Wareham, Kathryn E Bradbury, Aurora Perez-Cornago, Konstantinos K Tsilidis, Pietro Ferrari, Elio Riboli, Marc J Gunter, Mathilde Touvier
Nov 21, 2018
BACKGROUND: Helping consumers make healthier food choices is a key issue for the prevention of cancer and other diseases. In many countries, political authorities are considering the implementation of a simplified labelling...
Somatic genetic rescue of a germline ribosome assembly defect.
Shengjiang Tan, Laëtitia Kermasson, Christine Hilcenko, Vasileios Kargas, David Traynor, Ahmed Zakaria Boukerrou, Norberto Escudero-Urquijo, Alexandre Faille, Alexis Bertrand, Maxim Rossmann, Beatriz Goyenechea, Li Jin, Jonathan Moreil, Olivier Alibeu, Blandine Beaupain, Christine Bôle-Feysot, Stefano Fumagalli, Sophie Kaltenbach, Jean-Alain Martignoles, Cécile Masson, Patrick Nitschké, Mélanie Parisot, Aurore Pouliet, Isabelle Radford-Weiss, Frédéric Tores, Jean-Pierre de Villartay, Mohammed Zarhrate, Ai Ling Koh, Kong Boo Phua, Bruno Reversade, Peter J Bond, Christine Bellanné-Chantelot, Isabelle Callebaut, François Delhommeau, Jean Donadieu, Alan Warren, Patrick Revy
Jul 14, 2021
Germ Cells Cells Cultured Ribosomes Animals Humans Drosophila Dictyostelium Saccharomyces cerevisiae Proteins Ribonucleoprotein U5 Small Nuclear Peptide Elongation Factors Eukaryotic Initiation Factors Biological Phenomena Protein Biosynthesis Protein Binding Sequence Homology Amino Acid Mutation Adolescent Adult Child Child Preschool Infant Ribosome Subunits Large Eukaryotic Young Adult Molecular Dynamics Simulation Shwachman-Diamond Syndrome
Somatic genetic rescue of a germline ribosome assembly defect.
Shengjiang Tan, Laëtitia Kermasson, Christine Hilcenko, Vasileios Kargas, David Traynor, Ahmed Z Boukerrou, Norberto Escudero-Urquijo, Alexandre Faille, Alexis Bertrand, Maxim Rossmann, Beatriz Goyenechea, Li Jin, Jonathan Moreil, Olivier Alibeu, Blandine Beaupain, Christine Bôle-Feysot, Stefano Fumagalli, Sophie Kaltenbach, Jean-Alain Martignoles, Cécile Masson, Patrick Nitschké, Mélanie Parisot, Aurore Pouliet, Isabelle Radford-Weiss, Frédéric Tores, Jean-Pierre de Villartay, Mohammed Zarhrate, Ai Ling Koh, Kong Boo Phua, Bruno Reversade, Peter J Bond, Christine Bellanné-Chantelot, Isabelle Callebaut, François Delhommeau, Jean Donadieu, Alan J Warren, Patrick Revy
Jun 29, 2022
Adolescent Adult Animals Biological Phenomena Cells Cultured Child Child Preschool Dictyostelium Drosophila Eukaryotic Initiation Factors Germ Cells Humans Infant Molecular Dynamics Simulation Mutation Peptide Elongation Factors Protein Binding Protein Biosynthesis Proteins Ribonucleoprotein U5 Small Nuclear Ribosome Subunits Large Eukaryotic Ribosomes Saccharomyces cerevisiae Sequence Homology Amino Acid Shwachman-Diamond Syndrome Young Adult
Somatic genetic rescue of a germline ribosome assembly defect
Shengjiang Tan, Laëtitia Kermasson, Christine Hilcenko, Vasileios Kargas, David Traynor, Ahmed Z. Boukerrou, Norberto Escudero-Urquijo, Alexandre Faille, Alexis Bertrand, Maxim Rossmann, Beatriz Goyenechea, Li Jin, Jonathan Moreil, Olivier Alibeu, Blandine Beaupain, Christine Bôle-Feysot, Stefano Fumagalli, Sophie Kaltenbach, Jean-Alain Martignoles, Cécile Masson, Patrick Nitschké, Mélanie Parisot, Aurore Pouliet, Isabelle Radford-Weiss, Frédéric Tores, Jean-Pierre de Villartay, Mohammed Zarhrate, Ai Ling Koh, Kong Boo Phua, Bruno Reversade, Peter J. Bond, Christine Bellanné-Chantelot, Isabelle Callebaut, François Delhommeau, Jean Donadieu, Alan J. Warren, Patrick Revy
Aug 19, 2021
Abstract: Indirect somatic genetic rescue (SGR) of a germline mutation is thought to be rare in inherited Mendelian disorders. Here, we establish that acquired mutations in the EIF6 gene are a frequent mechanism of SGR in...
Association between nutritional profiles of foods underlying Nutri-Score front-of-pack labels and mortality
Mélanie Deschasaux, Inge Huybrechts, Chantal Julia, Serge Hercberg, Manon Egnell, Bernard Srour, Emmanuelle Kesse-Guyot, Paule Latino-Martel, Carine Biessy, Corinne Casagrande, Neil Murphy, Mazda Jenab, Heather A Ward, Elisabete Weiderpass, Kim Overvad, Anne Tjønneland, Agnetha Linn Rostgaard-Hansen, Marie-Christine Boutron-Ruault, Francesca Romana Mancini, Yahya Mahamat-Saleh, Tilman Kühn, Verena Katzke, Manuela M Bergmann, Matthias B Schulze, Antonia Trichopoulou, Anna Karakatsani, Eleni Peppa, Giovanna Masala, Claudia Agnoli, Maria Santucci de Magistris, Rosario Tumino, Carlotta Sacerdote, Jolanda MA Boer, WM Monique Verschuren, Yvonne T van der Schouw, Guri Skeie, Tonje Braaten, M Luisa Redondo, Antonio Agudo, Dafina Petrova, Sandra M Colorado-Yohar, Aurelio Barricarte, Pilar Amiano, Emily Sonestedt, Ulrika Ericson, Julia Otten, Björn Sundström, Nicholas J Wareham, Nita G Forouhi, Paolo Vineis, Konstantinos K Tsilidis, Anika Knuppel, Keren Papier, Pietro Ferrari, Elio Riboli, Marc J Gunter, Mathilde Touvier
Nov 16, 2020
OBJECTIVE: To determine if the Food Standards Agency nutrient profiling system (FSAm-NPS), which grades the nutritional quality of food products and is used to derive the Nutri-Score front-of-packet label to guide consumers...
Association between nutritional profiles of foods underlying Nutri-Score front-of-pack labels and mortality
Mélanie Deschasaux, Inge Huybrechts, Chantal Julia, Serge Hercberg, Manon Egnell, Bernard Srour, Emmanuelle Kesse-Guyot, Paule Latino-Martel, Carine Biessy, Corinne Casagrande, Neil Murphy, Mazda Jenab, Heather A Ward, Elisabete Weiderpass, Kim Overvad, Anne Tjønneland, Agnetha Linn Rostgaard-Hansen, Marie-Christine Boutron-Ruault, Francesca Romana Mancini, Yahya Mahamat-Saleh, Tilman Kühn, Verena Katzke, Manuela M Bergmann, Matthias B Schulze, Antonia Trichopoulou, Anna Karakatsani, Eleni Peppa, Giovanna Masala, Claudia Agnoli, Maria Santucci de Magistris, Rosario Tumino, Carlotta Sacerdote, Jolanda MA Boer, WM Monique Verschuren, Yvonne T van der Schouw, Guri Skeie, Tonje Braaten, M Luisa Redondo, Antonio Agudo, Dafina Petrova, Sandra M Colorado-Yohar, Aurelio Barricarte, Pilar Amiano, Emily Sonestedt, Ulrika Ericson, Julia Otten, Björn Sundström, Nicholas J Wareham, Nita G Forouhi, Paolo Vineis, Konstantinos K Tsilidis, Anika Knuppel, Keren Papier, Pietro Ferrari, Elio Riboli, Marc J Gunter, Mathilde Touvier
Sep 17, 2020
Abstract: Objective: To determine if the Food Standards Agency nutrient profiling system (FSAm-NPS), which grades the nutritional quality of food products and is used to derive the Nutri-Score front-of-packet label to guide...
Consistently dated Atlantic sediment cores over the last 40 thousand years
Claire Waelbroeck, Bryan C. Lougheed, Natalia Vazquez Riveiros, Lise Missiaen, Joel Pedro, Trond Dokken, Irka Hajdas, Lukas Wacker, Peter Abbott, Jean-Pascal Dumoulin, François Thil, Frédérique Eynaud, Linda Rossignol, Wiem Fersi, Ana Luiza Albuquerque, Helge Arz, William E. N. Austin, Rosemarie Came, Anders E. Carlson, James A. Collins, Bernard Dennielou, Stéphanie Desprat, Alex Dickson, Mary Elliot, Christa Farmer, Jacques Giraudeau, Julia Gottschalk, Jorijntje Henderiks, Konrad Hughen, Simon Jung, Paul Knutz, Susana Lebreiro, David C. Lund, Jean Lynch-Stieglitz, Bruno Malaizé, Thomas Marchitto, Gema Martínez-Méndez, Gesine Mollenhauer, Filipa Naughton, Silvia Nave, Dirk Nürnberg, Delia Oppo, Victoria Peck, Frank J. C. Peeters, Aurélie Penaud, Rodrigo da Costa Portilho-Ramos, Janne Repschläger, Jenny Roberts, Carsten Rühlemann, Emilia Salgueiro, Maria Fernanda Sanchez Goni, Joachim Schönfeld, Paolo Scussolini, Luke C. Skinner, Charlotte Skonieczny, David Thornalley, Samuel Toucanne, David Van Rooij, Laurence Vidal, Antje H. L. Voelker, Mélanie Wary, Syee Weldeab, Martin Ziegler
Sep 01, 2020
Abstract: Rapid changes in ocean circulation and climate have been observed in marine-sediment and ice cores over the last glacial period and deglaciation, highlighting the non-linear character of the climate system and...
Consistently dated Atlantic sediment cores over the last 40 thousand years.
Claire Waelbroeck, Bryan C Lougheed, Natalia Vazquez Riveiros, Lise Missiaen, Joel Pedro, Trond Dokken, Irka Hajdas, Lukas Wacker, Peter Abbott, Jean-Pascal Dumoulin, François Thil, Frédérique Eynaud, Linda Rossignol, Wiem Fersi, Ana Luiza Albuquerque, Helge Arz, William EN Austin, Rosemarie Came, Anders E Carlson, James A Collins, Bernard Dennielou, Stéphanie Desprat, Alex Dickson, Mary Elliot, Christa Farmer, Jacques Giraudeau, Julia Gottschalk, Jorijntje Henderiks, Konrad Hughen, Simon Jung, Paul Knutz, Susana Lebreiro, David C Lund, Jean Lynch-Stieglitz, Bruno Malaizé, Thomas Marchitto, Gema Martínez-Méndez, Gesine Mollenhauer, Filipa Naughton, Silvia Nave, Dirk Nürnberg, Delia Oppo, Victoria Peck, Frank JC Peeters, Aurélie Penaud, Rodrigo da Costa Portilho-Ramos, Janne Repschläger, Jenny Roberts, Carsten Rühlemann, Emilia Salgueiro, Maria Fernanda Sanchez Goni, Joachim Schönfeld, Paolo Scussolini, Luke C Skinner, Charlotte Skonieczny, David Thornalley, Samuel Toucanne, David Van Rooij, Laurence Vidal, Antje HL Voelker, Mélanie Wary, Syee Weldeab, Martin Ziegler
Nov 20, 2019
Rapid changes in ocean circulation and climate have been observed in marine-sediment and ice cores over the last glacial period and deglaciation, highlighting the non-linear character of the climate system and underlining the...
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