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Results: 242
Systematic selection of small molecules to promote differentiation of embryonic stem cells and experimental validation for generating cardiomyocytes.
Transcriptional drug repositioning and cheminformatics approach for differentiation therapy of leukaemia cells.
Yasaman KalantarMotamedi, Fatemeh Ejeian, Faezeh Sabouhi, Leila Bahmani, Alireza Shoaraye Nejati, Aditya Mukund Bhagwat, Ali Mohammad Ahadi, Azita Parvaneh Tafreshi, Mohammad Hossein Nasr-Esfahani, Andreas Bender
Aug 13, 2021
Differentiation therapy is attracting increasing interest in cancer as it can be more specific than conventional chemotherapy approaches, and it has offered new treatment options for some cancer types, such as treating acute...
Transcriptional drug repositioning and cheminformatics approach for differentiation therapy of leukaemia cells
Yasaman KalantarMotamedi, Fatemeh Ejeian, Faezeh Sabouhi, Leila Bahmani, Alireza Shoaraye Nejati, Aditya Mukund Bhagwat, Ali Mohammad Ahadi, Azita Parvaneh Tafreshi, Mohammad Hossein Nasr-Esfahani, Andreas Bender
Jun 15, 2021
What is the impact of structural and cultural factors and interventions within educational settings on promoting positive mental health and preventing poor mental health
David Troy, Joanna Anderson, Patricia E Jessiman, Patricia N Albers, Joanna G Williams, Seamus Sheard, Emma Geijer-Simpson, Liam Spencer, Eileen Kaner, Mark Limmer, Russell Viner, Judi Kidger
Mar 17, 2022
Mental health (MH) difficulties are on the increase among children and young people (CYP). Evidence has shown that educational settings contain both risk and protective factors for MH. This review investigated which structural...
Life satisfaction and mental health from age 17 to 21 years in a general population sample.
Adolescence is a period when both mental health (MH) and wellbeing start deteriorating, which raises the question of how the two phenomena are linked and whether deterioration in one might be used to flag problematic...
Family focused interventions that address parental domestic violence and abuse, mental ill-health, and substance misuse in combination
Kate Allen, GJ Melendez-Torres, Tamsin Ford, Chris Bonell, Katie Finning, Mary Fredlund, Alexa Gainsbury, Vashti Berry
Sep 02, 2022
Parental domestic violence and abuse (DVA), mental ill-health (MH), and substance misuse (SU) are three public health issues that tend to cluster within families, risking negative impacts for both parents and children. Despite...
Family focused interventions that address parental domestic violence and abuse, mental ill-health, and substance misuse in combination
Kate Allen, GJ Melendez-Torres, Tamsin Ford, Chris Bonell, Katie Finning, Mary Fredlund, Alexa Gainsbury, Vashti Berry
Jul 29, 2022
Parental domestic violence and abuse (DVA), mental ill-health (MH), and substance misuse (SU) are three public health issues that tend to cluster within families, risking negative impacts for both parents and children. Despite...
Public opinion on sharing data from health services for clinical and research purposes without explicit consent
Linda A Jones, Jenny R Nelder, Joseph M Fryer, Philip H Alsop, Michael R Geary, Mark Prince, Rudolf Cardinal
May 02, 2022
Objectives: UK National Health Service/Health and Social Care (NHS/HSC) data are variably shared between healthcare organisations for direct care, and increasingly de-identified for research. Few large-scale studies have...
Back to the Populist Future?
MH Kenny
Jul 31, 2017
Nostalgia is regularly depicted as an indication of a flawed political argument or allegiance, and framed as a virus more likely to take hold in places that are ‘left behind’. Its prevalence has been linked to the rise of...
Freedom of expression as self-restraint
In my recent book Freedom of Expression as Self-Restraint, I expound and defend the moral principle of freedom of expression. This article recounts a few of the main strands of the exposition in that book, and it...
MH Kramer
May 09, 2022
There's Nothing Quasi about Quasi-Realism
MH Kramer
Feb 09, 2017
This paper seeks to clarify and defend the proposition that moral realism is best elaborated as a moral doctrine. I begin by upholding Ronald Dworkin’s anti-Archimedean critique of the error theory against some strictures by...
Dual-Level Location Suitability Index for Optimum Site Selection
COVID-19 pandemic has spread rapidly affecting the entire world. During the fight against the pandemic, hospitals are insufficient to meet the needs. This study aims to set the basis for optimal site selection of quarantine...
Published by: IGI Global Scientific Publishing
Reflections on 40 years of IVF.
The past For many practitioners of in vitro fertilisation (IVF) today, it must be hard to comprehend the disdain and disgust with which the introduction of IVF as therapy for infertility was greeted. The ethical and legal...
Association between temporal patterns of baroreflex sensitivity after traumatic brain injury and prognosis
Agnieszka Uryga, Magdalena Kasprowicz, Małgorzata Burzyńska, Agnieszka Kazimierska, Marek Czosnyka, Nathalie Nasr
Apr 14, 2023
INTRODUCTION: Traumatic brain injury (TBI) may lead to an increase in intracranial pressure (ICP) as well as impairment of cerebral vascular reactivity and the autonomic nervous system. This study aimed to investigate individual...
Neutron Reflectometry for Studying Corrosion and Corrosion Inhibition
Neutron reflectometry is an extremely powerful technique to monitor chemical and morphological changes at interfaces at the angstrom-level. Its ability to characterise metal, oxide and organic layers simultaneously or separately...
Identifying the effects of sanctions on the Iranian economy using newspaper coverage
Summary: This paper focuses on the identification and quantitative estimation of sanctions on the Iranian economy over the period 1989–2019. It provides a new time series approach and proposes a novel measure of sanctions...
Measurement of factor strength
Abstract: This paper proposes an estimator of factor strength and establishes its consistency and asymptotic distribution. The estimator is based on the number of statistically significant factor loadings, taking multiple...
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