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Results: 351
Mi-2/NuRD complex protects stem cell progeny from mitogenic Notch signaling.
To progress towards differentiation, progeny of stem cells need to extinguish expression of stem-cell maintenance genes. Failures in such mechanisms can drive tumorigenesis. In Drosophila neural stem cell (NSC) lineages...
D. melanogaster Notch NuRD Complex Chromosomes developmental biology Gene Expression Stem Cells Adenosine Triphosphatases Animals Autoantigens Basic Helix-Loop-Helix Transcription Factors Carcinogenesis Cell Differentiation Cell Lineage Cell Proliferation Drosophila Proteins Drosophila melanogaster Gene Expression Regulation Developmental Humans Hyperplasia Models Biological Neural Stem Cells Neurons Protein Binding Receptors Notch Repressor Proteins Signal Transduction
On the Shores of Politics
RORY O'BRYEN
Apr 20, 2018
This article explores discourses surrounding the modernisation of the state and the formation of national literature in nineteenth‐century Colombia, examining the racism at the heart of both, particularly in their representation...
M2 Do patients and informal carers agree on symptom burden in advanced copd?
Objective: Accurate informal carer assessment of patient symptoms is likely to be valuable for decision-making in managing the high symptom burden of chronic obstructive pulmonary disease (COPD) in the home setting. Few studies...
Do patients and carers agree on symptom burden in advanced COPD?
Emma Mi, Ella Mi, Gail Ewing, Patrick White, Ravi Mahadeva, A Carole Gardener, Morag Farquhar
Apr 16, 2019
OBJECTIVE: Accurate informal carer assessment of patient symptoms is likely to be valuable for decision making in managing the high symptom burden of COPD in the home setting. Few studies have investigated agreement between...
COPD agreement Informal carers symptom Adaptation Psychological Aged Caregivers Cost of Illness Cross-Sectional Studies Female Health Knowledge Attitudes practice health status Humans Male Mental Health Middle Aged Patients Prognosis Prospective Studies Pulmonary Disease Chronic Obstructive Quality of life Risk Factors Severity of Illness Index
Deepwater Horizon oil spill exposures and nonfatal myocardial infarction in the GuLF STUDY.
Jean Strelitz, Lawrence S Engel, Richard K Kwok, Aubrey K Miller, Aaron Blair, Dale P Sandler
Jul 17, 2019
BACKGROUND: Workers involved in the response and clean-up of the 2010 Deepwater Horizon oil spill faced possible exposures to crude oil, burning oil, dispersants and other pollutants in addition to physical and emotional stress....
Deepwater Horizon Disaster epidemiology Myocardial Infarction Oil spill Adult Aged Cohort Studies Female Gulf of Mexico Humans Incidence Male Middle Aged Myocardial Infarction occupational exposure Petroleum Petroleum Pollution Prospective Studies Self Report Southeastern United States Water Pollutants Chemical Young Adult
Liver-heart crosstalk controls IL-22 activity in cardiac protection after myocardial infarction.
Ting-Ting Tang, Yuan-Yuan Li, Jing-Jing Li, Ke Wang, Yue Han, Wen-Yong Dong, Zheng-Feng Zhu, Ni Xia, Shao-Fang Nie, Min Zhang, Zhi-Peng Zeng, Bing-Jie Lv, Jiao Jiao, Heng Liu, Zong-Shu Xian, Xiang-Ping Yang, Yu Hu, Yu-Hua Liao, Qing Wang, Xin Tu, Ziad Mallat, Yu Huang, Guo-Ping Shi, Xiang Cheng
Nov 22, 2018
Interleukin (IL)-22 regulates tissue inflammation and repair. Here we report participation of the liver in IL-22-mediated cardiac repair after acute myocardial infarction (MI). Methods: We induced experimental MI in mice by...
Handling missing data in matched case-control studies using multiple imputation.
Analysis of matched case-control studies is often complicated by missing data on covariates. Analysis can be restricted to individuals with complete data, but this is inefficient and may be biased. Multiple imputation (MI) is an...
Motivational interviewing competencies among UK family nurse partnership nurses
Sue Channon, Marie Jet Bekkers, Julia Sanders, Rebecca Cannings-John, Laura Robertson, Kristina Bennert, Christopher Butler, Kerenza Hood, Michael Robling
Sep 20, 2016
Background: Motivational Interviewing (MI) is a person-centred counselling approach to behaviour change which is increasingly being used in public health settings, either as a stand-alone approach or in combination with other...
Encompassing new use cases - level 3.0 of the HUPO-PSI format for molecular interactions.
M Sivade Dumousseau, D Alonso-López, M Ammari, G Bradley, NH Campbell, A Ceol, G Cesareni, C Combe, J De Las Rivas, N Del-Toro, J Heimbach, H Hermjakob, I Jurisica, M Koch, L Licata, RC Lovering, DJ Lynn, BHM Meldal, G Micklem, S Panni, P Porras, S Ricard-Blum, B Roechert, L Salwinski, A Shrivastava, J Sullivan, N Thierry-Mieg, Y Yehudi, K Van Roey, S Orchard
Sep 08, 2018
BACKGROUND: Systems biologists study interaction data to understand the behaviour of whole cell systems, and their environment, at a molecular level. In order to effectively achieve this goal, it is critical that researchers...
Almost global convergence to practical synchronization in the generalized Kuramoto model on networks over the n-sphere
Abstract From the flashing of fireflies to autonomous robot swarms, synchronization phenomena are ubiquitous in nature and technology. They are commonly described by the Kuramoto model that, in...
Acute regional changes in myocardial strain may predict ventricular remodelling after myocardial infarction in a large animal model.
DS Mansell, VD Bruno, E Sammut, A Chiribiri, T Johnson, I Khaliulin, D Baz Lopez, HS Gill, KH Fraser, M Murphy, T Krieg, MS Suleiman, S George, R Ascione, AN Cookson
Oct 08, 2021
To identify predictors of left ventricular remodelling (LVR) post-myocardial infarction (MI) and related molecular signatures, a porcine model of closed-chest balloon MI was used along with serial cardiac magnetic resonance...
Animals Biomarkers Computational Biology Data analysis Data Interpretation Statistical Disease Models Animal Disease Susceptibility Female Image Processing Computer-Assisted Magnetic Resonance Imaging Myocardial Infarction Myocardium Proteome Proteomics Reproducibility of Results Swine Translational Research Biomedical Ventricular Function Left Ventricular Remodeling
Multiple imputation of missing data in nested case-control and case-cohort studies.
The nested case-control and case-cohort designs are two main approaches for carrying out a substudy within a prospective cohort. This article adapts multiple imputation (MI) methods for handling missing covariates in full-cohort...
Predicting risk of cardiovascular events 1 to 3 years post-myocardial infarction using a global registry.
Stuart J Pocock, David Brieger, John Gregson, Ji Y Chen, Mauricio G Cohen, Shaun G Goodman, Christopher B Granger, Richard Grieve, Jose C Nicolau, Tabassome Simon, Dirk Westermann, Satoshi Yasuda, Katarina Hedman, Kirsten L Rennie, Karolina Andersson Sundell, TIGRIS Study Investigators
Jan 16, 2020
BACKGROUND: Risk prediction tools are lacking for patients with stable disease some years after myocardial infarction (MI). HYPOTHESIS: A practical long-term cardiovascular risk index can be developed. METHODS: The long-Term...
English Article Style Recognition and Matching by Using Web Semantics
With the explosion of internet information, people feel helpless and difficult to choose in the face of massive information. However, the traditional method to organize a huge set of original documents is not only time-consuming...
Published by: IGI Global Scientific Publishing
Non-destructive testing and evaluation of composite materials/structures
Composite materials/structures are advancing in product efficiency,
cost-effectiveness and the development of superior specific properties. There
are increasing demands in their applications to load-carrying structures...
Endothelial Cell Indoleamine 2, 3-Dioxygenase 1 Alters Cardiac Function After Myocardial Infarction Through Kynurenine.
Nada Joe Melhem, Mouna Chajadine, Ingrid Gomez, Kiave-Yune Howangyin, Marion Bouvet, Camille Knosp, Yanyi Sun, Marie Rouanet, Ludivine Laurans, Olivier Cazorla, Mathilde Lemitre, José Vilar, Ziad Mallat, Alain Tedgui, Hafid Ait-Oufella, Jean-Sébastien Hulot, Jacques Callebert, Jean-Marie Launay, Jeremy Fauconnier, Jean-Sébastien Silvestre, Soraya Taleb
Dec 07, 2020
BACKGROUND: Ischemic cardiovascular diseases, particularly acute myocardial infarction (MI), is one of the leading causes of mortality worldwide. Indoleamine 2, 3-dioxygenase 1 (IDO) catalyzes 1 rate-limiting step of...
Healthcare Automation System by Using Cloud-Based Telemonitoring Technique for Cardiovascular Disease Classification
This paper illustrates the cloud-based telemonitoring framework that implements healthcare automation system for myocardial infarction (MI) disease classification. For this purpose, the pathological feature of ECG signal such as...
Published by: IGI Global Scientific Publishing
Acute regional changes in myocardial strain may predict ventricular remodelling after myocardial infarction in a large animal model
Doyin Odunmbaku-Mansell, V. D. Bruno, Eva Sammut, Amedeo Chiribiri, Thomas Johnson, I Khaliulin, Daniel Baz Lopez, H S Gill, Katharine Fraser, M Murphy, T Krieg, M. S. Suleiman, S George, Raimondo Ascione, Andrew Cookson
Sep 15, 2021
To identify predictors of left ventricular remodelling (LVR) post-myocardial infarction (MI) and related molecular signatures, a porcine model of closed-chest balloon MI was used along with serial cardiac magnetic resonance...
Positron emission tomography-guided magnetic resonance spectroscopy in Alzheimer disease.
Nasim Sheikh-Bahaei, S Ahmad Sajjadi, Roido Manavaki, Mary McLean, John T O'Brien, Jonathan H Gillard
Mar 13, 2018
OBJECTIVE: To determine whether the level of metabolites in magnetic resonance spectroscopy (MRS) is a representative marker of underlying pathological changes identified in positron emission tomographic (PET) images in...
Re-entrance and entanglement in the one-dimensional Bose-Hubbard model
Re-entrance is a novel feature where the phase boundaries of a system exhibit a succession of transitions between two phases A and B, like A-B-A-B, when just one parameter is varied monotonically. This type of re-entrance is...
Sex-Specific Computed Tomography Coronary Plaque Characterization and Risk of Myocardial Infarction.
Michelle C Williams, Jacek Kwiecinski, Mhairi Doris, Priscilla McElhinney, Michelle S D'Souza, Sebastien Cadet, Philip D Adamson, Alastair J Moss, Shirjel Alam, Amanda Hunter, Anoop SV Shah, Nicholas L Mills, Tania Pawade, Chengjia Wang, Jonathan R Weir-McCall, Michael Bonnici-Mallia, Christopher Murrills, Giles Roditi, Edwin JR van Beek, Leslee J Shaw, Edward D Nicol, Daniel S Berman, Piotr J Slomka, David E Newby, Marc R Dweck, Damini Dey
Apr 23, 2021
OBJECTIVES: This study was designed to investigate whether coronary computed tomography angiography assessments of coronary plaque might explain differences in the prognosis of men and women presenting with chest pain....
Computed tomography computed tomography coronary angiography Coronary Artery Disease quantitative plaque analysis sex Computed Tomography Angiography Coronary Angiography Coronary Artery Disease Coronary Vessels Female Humans Male Myocardial Infarction Plaque Atherosclerotic Predictive Value of Tests Risk Factors
Motivational interviewing competencies among UK family nurse partnership nurses
Sue Channon, Marie Jet Bekkers, Julia Sanders, Rebecca Cannings-John, Laura Robertson, Kristina Bennert, Christopher Butler, Kerenza Hood, Michael Robling
Sep 20, 2016
Background: Motivational Interviewing (MI) is a person-centred counselling approach to behaviour change which is increasingly being used in public health settings, either as a stand-alone approach or in combination with other...
Association of Cardiometabolic Multimorbidity With Mortality.
Emerging Risk Factors Collaboration, Emanuele Di Angelantonio, Stephen Kaptoge, David Wormser, Peter Willeit, Adam S Butterworth, Narinder Bansal, Linda M O'Keeffe, Pei Gao, Angela M Wood, Stephen Burgess, Daniel F Freitag, Lisa Pennells, Sanne A Peters, Carole L Hart, Lise Lund Håheim, Richard F Gillum, Børge G Nordestgaard, Bruce M Psaty, Bu B Yeap, Matthew W Knuiman, Paul J Nietert, Jussi Kauhanen, Jukka T Salonen, Lewis H Kuller, Leon A Simons, Yvonne T van der Schouw, Elizabeth Barrett-Connor, Randi Selmer, Carlos J Crespo, Beatriz Rodriguez, WM Monique Verschuren, Veikko Salomaa, Kurt Svärdsudd, Pim van der Harst, Cecilia Björkelund, Lars Wilhelmsen, Robert B Wallace, Hermann Brenner, Philippe Amouyel, Elizabeth LM Barr, Hiroyasu Iso, Altan Onat, Maurizio Trevisan, Ralph B D'Agostino, Cyrus Cooper, Maryam Kavousi, Lennart Welin, Ronan Roussel, Frank B Hu, Shinichi Sato, Karina W Davidson, Barbara V Howard, Maarten JG Leening, Maarten Leening, Annika Rosengren, Marcus Dörr, Dorly JH Deeg, Stefan Kiechl, Coen DA Stehouwer, Aulikki Nissinen, Simona Giampaoli, Chiara Donfrancesco, Daan Kromhout, Jackie F Price, Annette Peters, Tom W Meade, Edoardo Casiglia, Debbie A Lawlor, John Gallacher, Dorothea Nagel, Oscar H Franco, Gerd Assmann, Gilles R Dagenais, J Wouter Jukema, Johan Sundström, Mark Woodward, Eric J Brunner, Kay-Tee Khaw, Nicholas J Wareham, Eric A Whitsel, Inger Njølstad, Bo Hedblad, Sylvia Wassertheil-Smoller, Gunnar Engström, Wayne D Rosamond, Elizabeth Selvin, Naveed Sattar, Simon G Thompson, John Danesh
Mar 08, 2019
IMPORTANCE: The prevalence of cardiometabolic multimorbidity is increasing. OBJECTIVE: To estimate reductions in life expectancy associated with cardiometabolic multimorbidity. DESIGN, SETTING, AND PARTICIPANTS: Age- and...
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