Search
Results: 5
Moral dilemmas and trust in leaders during a global health crisis
Jim A.C. Everett, Clara Colombatto, Edmond Awad, Paulo Boggio, Björn Bos, William J. Brady, Megha Chawla, Vladimir Chituc, Dongil Chung, Moritz A. Drupp, Srishti Goel, Brit Grosskopf, Frederik Hjorth, Alissa Ji, Caleb Kealoha, Judy S. Kim, Yangfei Lin, Yina Ma, Michel André Maréchal, Federico Mancinelli, Christoph Mathys, Asmus L. Olsen, Graeme Pearce, Annayah M.B. Prosser, Niv Reggev, Nicholas Sabin, Julien Senn, Yeon Soon Shin, Walter Sinnott-Armstrong, Hallgeir Sjåstad, Madelijn Strick, Sunhae Sul, Lars Tummers, Monique Turner, Hongbo Yu, Yoonseo Zoh, Molly J. Crockett
Aug 31, 2021
Abstract: Trust in leaders is central to citizen compliance with public policies. One potential determinant of trust is how leaders resolve conflicts between utilitarian and non-utilitarian ethical principles in moral...
Moral dilemmas and trust in leaders during a global health crisis
Jim A.C. Everett, Clara Colombatto, Edmond Awad, Paulo Boggio, Björn Bos, William J. Brady, Megha Chawla, Vladimir Chituc, Dongil Chung, Moritz A. Drupp, Srishti Goel, Brit Grosskopf, Frederik Hjorth, Alissa Ji, Caleb Kealoha, Judy S. Kim, Yangfei Lin, Yina Ma, Michel André Maréchal, Federico Mancinelli, Christoph Mathys, Asmus L. Olsen, Graeme Pearce, Annayah M.B. Prosser, Niv Reggev, Nicholas Sabin, Julien Senn, Yeon Soon Shin, Walter Sinnott-Armstrong, Hallgeir Sjåstad, Madelijn Strick, Sunhae Sul, Lars Tummers, Monique Turner, Hongbo Yu, Yoonseo Zoh, Molly J. Crockett
Aug 31, 2021
Abstract: Trust in leaders is central to citizen compliance with public policies. One potential determinant of trust is how leaders resolve conflicts between utilitarian and non-utilitarian ethical principles in moral...
Dissection of DNA double-strand-break repair using novel single-molecule forceps.
Jing L Wang, Camille Duboc, Qian Wu, Takashi Ochi, Shikang Liang, Susan E Tsutakawa, Susan P Lees-Miller, Marc Nadal, John A Tainer, Tom L Blundell, Terence R Strick
Jan 07, 2021
Repairing DNA double-strand breaks (DSBs) by nonhomologous end joining (NHEJ) requires multiple proteins to recognize and bind DNA ends, process them for compatibility, and ligate them together. We constructed novel DNA...
Targeted gene correction of α1-antitrypsin deficiency in induced pluripotent stem cells.
Kosuke Yusa, S Tamir Rashid, Helene Strick-Marchand, Ignacio Varela, Pei-Qi Liu, David E Paschon, Elena Miranda, Adriana Ordóñez, Nicholas RF Hannan, Foad J Rouhani, Sylvie Darche, Graeme Alexander, Stefan J Marciniak, Noemi Fusaki, Mamoru Hasegawa, Michael C Holmes, James P Di Santo, David A Lomas, Allan Bradley, Ludovic Vallier
Oct 22, 2020
Human induced pluripotent stem cells (iPSCs) represent a unique opportunity for regenerative medicine because they offer the prospect of generating unlimited quantities of cells for autologous transplantation, with potential...
Mechanism of efficient double-strand break repair by a long non-coding RNA.
Roopa Thapar, Jing L Wang, Michal Hammel, Ruiqiong Ye, Ke Liang, Chengcao Sun, Ales Hnizda, Shikang Liang, Su S Maw, Linda Lee, Heather Villarreal, Isaac Forrester, Shujuan Fang, Miaw-Sheue Tsai, Tom L Blundell, Anthony J Davis, Chunru Lin, Susan P Lees-Miller, Terence R Strick, John A Tainer
Nov 30, 2020
Mechanistic studies in DNA repair have focused on roles of multi-protein DNA complexes, so how long non-coding RNAs (lncRNAs) regulate DNA repair is less well understood. Yet, lncRNA LINP1 is over-expressed in multiple cancers...