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Madeline Hepburn is Missing: A Creative Look into Stylistic Writing
Ze'ev A Shaheen
Jan 01, 0001
After the disappearance of a young woman named Madeline Hepburn, Martin Wright is brought in for questioning. Wright is a stranger with a checkered past in a new town and an inclination for conversation. The story is formatted...
fiction Creative Writing short story Arts and Humanities Creative Writing English Language and Literature fiction
Published by: Ursinus College
Measuring cerebral perfusion with [11C]-PiB R1 in Down syndrome
Elijah Mak, Monika Grigorova, Jessica Beresford-Webb, Maura Malpetti, Madeline Walpert, Stephanie Brown, Elizabeth Jones, Isabel Clare, Young T Hong, Tim D Fryer, Jonathan P Coles, Franklin I Aigbirhio, David K Menon, Peter J Nestor, Anthony J Holland, Shahid H Zaman
Oct 26, 2020
Positron emission tomography imaging of glucose hypometabolism and amyloid deposition are two well-established methods to evaluate preclinical changes in Alzheimer's disease and people with Down syndrome. However, the use of...
'The Additional Attraction of Affliction'
CH Walker-Gore
Apr 28, 2017
WHILE THERE IS NEVER any serious doubt that Mr. Arabin, clergyman hero of Anthony Trollope’s Barchester Towers (1857), is destined to marry our heroine, Eleanor Bold, there are moments in the novel when he is all but overcome by...
Disease modelling in human organoids.
The past decade has seen an explosion in the field of in vitro disease modelling, in particular the development of organoids. These self-organizing tissues derived from stem cells provide a unique system to examine mechanisms...
Health is Wealth: The Correlation of Wellness Programs & Productivity in Canada and the U.S.
Madeline Wert
Jan 01, 0001
Does health impact the productivity of workers? Are there differences between the U.S. and Canada? Firms both in Canada and the U.S. deal with issues of presenteeism and absenteeism. Presenteeism is when an employee shows up to...
Workplace wellness programs Public Health gdp presenteeism Absenteeism Health insurance United States Canada incentives productivity Business Economics Public Health Social and Behavioral Sciences
Published by: Ursinus College
A Systematic Review of Unexplained Early Regression in Adolescents and Adults with Down Syndrome.
A proportion of young people with Down syndrome (DS) experience unexplained regression that severely impacts on their daily lives. While this condition has been recognised by clinicians, there is a limited understanding of...
Generation of Fluorescent Esophageal Adenocarcinoma Cells for Lineage Tracing Within Composite 3D Culture Models
Madeline G Linker
Jan 01, 0001
While relatively rare, the aggressive nature and poor prognosis associated with esophageal carcinoma make it a particularly dangerous form of cancer. One approach to discovering esophageal cancer treatment options includes the...
Published by: Winthrop University
Increased choroidal thickness in adults with Down syndrome.
Lajos Csincsik, Rachel Nelson, Madeleine J Walpert, Tunde Peto, Anthony Holland, Imre Lengyel
Mar 30, 2021
INTRODUCTION: People with Down syndrome (DS) are particularly susceptible to Alzheimer's disease (AD) due to the triplication of the amyloid precursor protein (APP) gene. In this cross-sectional study, we hypothesized that...
A Systematic Review of Unexplained Early Regression in Adolescents and Adults with Down Syndrome
A proportion of young people with Down syndrome (DS) experience unexplained regression that severely impacts on their daily lives. While this condition has been recognised by clinicians, there is a limited understanding of...
The Grizzly, September 26, 2024
Kate Horan, Caitlin Cunnane, Sidney Belleroche, Ella Schneider, Henry Probolus, Estella Bower, Adam Denn, Grace Lynch
Jan 01, 0001
New Member Education Begins October is Lantern Submission Month Yik Yak Culture Madeline Hepburn is Missing: A Short Story by Ze'ev Shaheen Love of the Craft Opinions: PSA: Flush the Toilet! Women's Soccer Soars to Great...
Ursinus College Collegeville Pennsylvania newspaper Kappa Delta Kappa Tilly Dumaine Lantern Social Media Ze'ev Shaheen Creative Writing Minecraft Soccer cultural history Higher Education Liberal Studies Social History United States History
Published by: Ursinus College
Beyond the Feeling Individual
Organizational scholars have treated emotions mostly as an individual-level phenomenon, with limited theorisation of emotions as an important component in social embeddedness. In this review essay, we argue for the need for a...
collective emotions embeddedness emotional capital emotional energy moral batteries social bonds /dk/atira/pure/subjectarea/asjc/1400/1405 name=Management of Technology and Innovation /dk/atira/pure/subjectarea/asjc/1400/1403 name=Business and International Management /dk/atira/pure/subjectarea/asjc/1400/1408 name=Strategy and Management
Beyond the Feeling Individual
Organizational scholars have treated emotions mostly as an individual-level phenomenon, with limited theorisation of emotions as an important component in social embeddedness. In this review essay, we argue for the need for a...
collective emotions embeddedness emotional capital emotional energy moral batteries social bonds /dk/atira/pure/subjectarea/asjc/1400/1405 name=Management of Technology and Innovation /dk/atira/pure/subjectarea/asjc/1400/1403 name=Business and International Management /dk/atira/pure/subjectarea/asjc/1400/1408 name=Strategy and Management
Breathwork Interventions for Adults with Clinically Diagnosed Anxiety Disorders
Blerida Banushi, Madeline Brendle, Anya Ragnhildstveit, Tara Murphy, Claire Moore, Johannes Egberts, Reid Robison
Mar 06, 2023
Evaluation of the Potential HMGA1-EF24 Nexus in Human Colon Cancer
The architectural chromatin binding proteins High Mobility Group A1 (HMGA1) are proteins expressed at high levels in malignant cancers and induce neoplastic transformation. The protein is increased as the last step of the...
Published by: Winthrop University
Trauma Management Therapy for First Responders
Mental health professionals are only recently beginning to understand the risks for stress-related disorders experienced by first responders. For example, it is clear that first responders are at increased risk for...
Mental Health & Behavioral Studies Medicine and Healthcare Psychiatry and Mental Health Social Sciences and Humanities
Published by: IGI Global Scientific Publishing
Breathwork Interventions for Adults with Clinically Diagnosed Anxiety Disorders
Blerida Banushi, Madeline Brendle, Anya Ragnhildstveit, Tara Murphy, Claire Moore, Johannes Egberts, Reid Robison
Mar 28, 2023
Anxiety disorders are the most common group of mental disorders, but they are often underrecognized and undertreated in primary care. Dysfunctional breathing is a hallmark of anxiety disorders; however, mainstays of treatments...
Stress Anxiety Hyperventilation Phobia agoraphobia Anxiety Disorders heart rate variability biofeedback pranayama diaphragmatic breathing breathwork
Published by: Brain sciences
Age-related retinal thickness in Down's syndrome
Madeleine J Walpert, Eduardo M Normando, Tiina Annus, Sally R Jennings, Liam R Wilson, Peter Watson, Shahid H Zaman, M Francesca Cordeiro, Anthony J Holland
Feb 07, 2020
Introduction:People with Down's syndrome (DS) have a high prevalence of early-onset Alzheimer's disease. Early markers of Alzheimer's disease pathology identifiable before clinical change are needed for the evaluation of...
Pyrenoid loss impairs carbon-concentrating mechanism induction and alters primary metabolism in Chlamydomonas reinhardtii.
Madeline C Mitchell, Gergana Metodieva, Metodi V Metodiev, Howard Griffiths, Moritz T Meyer
May 14, 2018
Carbon-concentrating mechanisms (CCMs) enable efficient photosynthesis and growth in CO2-limiting environments, and in eukaryotic microalgae localisation of Rubisco to a microcompartment called the pyrenoid is key. In the model...
An iPSC-derived vascular model of Marfan syndrome identifies key mediators of smooth muscle cell death.
Alessandra Granata, Felipe Serrano, William George Bernard, Madeline McNamara, Lucinda Low, Priya Sastry, Sanjay Sinha
Oct 31, 2016
Aortic Aneurysm Apoptosis Fibrillin-1 Gene Expression Regulation Humans Induced Pluripotent Stem Cells Kruppel-Like Factor 4 Kruppel-Like Transcription Factors Marfan Syndrome Models Biological Muscle Smooth Vascular Signal Transduction Transforming Growth Factor beta p38 Mitogen-Activated Protein Kinases
A fragment profiling approach to inhibitors of the orphan $\textit{M. tuberculosis}$ P450 CYP144A1
MADELINE Kavanagh, J Chenge, AZEDINE Zoufir, K McLean, AG Coyne, Andreas Bender, A Munro, C Abell
Mar 09, 2017
Bacterial Proteins Binding Sites Cloning Molecular Computational Biology Cytochrome P-450 Enzyme Inhibitors Cytochrome P-450 Enzyme System Escherichia coli Gene Expression Ligands Models Molecular Mycobacterium tuberculosis Peptide Fragments Phylogeny Protein Binding Recombinant Proteins Structural Homology Protein
Exploring electrophysiological markers of auditory predictive processes and pathological ageing in adults with Down's syndrome.
Chiara Avancini, Sally Jennings, Srivas Chennu, Valdas Noreika, April Le, Tristan A Bekinschtein, Madeleine J Walpert, Isabel CH Clare, Anthony J Holland, Shahid H Zaman, Howard Ring
Jul 25, 2022
Transcriptome Analyses of Mosaic (MSC) Mitochondrial Mutants of Cucumber in a Highly Inbred Nuclear Background.
Tomasz L Mróz, Sebastian Eves-van den Akker, Agata Bernat, Agnieszka Skarzyńska, Leszek Pryszcz, Madeline Olberg, Michael J Havey, Grzegorz Bartoszewski
Aug 31, 2018
Cucumber (Cucumis sativus L.) has a large, paternally transmitted mitochondrial genome. Cucumber plants regenerated from cell cultures occasionally show paternally transmitted mosaic (MSC) phenotypes, characterized by slower...
PPL-138 (BU10038)
Andrea Cippitelli, Madeline Martinez, Gilles Zribi, Gerta Cami-Kobeci, Stephen M. Husbands, Lawrence Toll
Jun 15, 2022
The search for new and effective treatments for cocaine use disorder (CUD) is a priority. We determined whether PPL-138 (BU10038), a compound with partial agonist activity at both nociceptin opioid peptide (NOP) and mu-opioid...
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