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Results: 537
Distraction towards contextual alcohol cues and craving are associated with levels of alcohol use among youth.
Timo Lehmann Kvamme, Kristine Rømer Thomsen, Mette Buhl Callesen, Nuria Doñamayor, Mads Jensen, Mads Uffe Pedersen, Valerie Voon
Dec 04, 2018
BACKGROUND: Controlling drinking behaviour requires the ability to block out distracting alcohol cues in situations in which drinking is inappropriate or harmful. However, at present few studies have investigated whether...
Pupillary reactivity to alcohol cues as a predictive biomarker of alcohol relapse following treatment in a pilot study.
Timo L Kvamme, Mads Uffe Pedersen, Morten Overgaard, Kristine Rømer Thomsen, Valerie Voon
Jan 17, 2019
RATIONALE: Identifying the predictors of relapse in detoxified alcohol-dependent patients is crucial for effective surveillance procedures and the optimization of treatment. Physiological measures such as functional MRI activity...
The myeloarchitecture of impulsivity
Camilla L Nord, Seung-Goo Kim, Mette Buhl Callesen, Timo L Kvamme, Mads Jensen, Mads Uffe Pedersen, Kristine Rømer Thomsen, Valerie Voon
Apr 05, 2019
Impulsivity has been suggested as a neurocognitive endophenotype conferring risk across a number of neuropsychiatric conditions, including substance and behavioural addictions, eating disorders, and attention...
Dynamics of chromatin accessibility and gene regulation by MADS-domain transcription factors in flower development.
Alice Pajoro, Pedro Madrigal, Jose M Muiño, José Tomás Matus, Jian Jin, Martin A Mecchia, Juan M Debernardi, Javier F Palatnik, Salma Balazadeh, Muhammad Arif, Diarmuid S Ó'Maoiléidigh, Frank Wellmer, Pawel Krajewski, José-Luis Riechmann, Gerco C Angenent, Kerstin Kaufmann
Jun 19, 2020
BACKGROUND: Development of eukaryotic organisms is controlled by transcription factors that trigger specific and global changes in gene expression programs. In plants, MADS-domain transcription factors act as master regulators...
Pilot study
In an attempt to improve attention bias modification (ABM), we tested whether an attentional training protocol which featured monetary operant conditioning of eye-gaze to avoid alcohol stimuli in alcohol-dependent patients could...
Relationships between resting conductances, excitability, and t-system ionic homeostasis in skeletal muscle.
Activation of skeletal muscle fibers requires rapid sarcolemmal action potential (AP) conduction to ensure uniform excitation along the fiber length, as well as successful tubular excitation to initiate excitation-contraction...
REST-mediated recruitment of polycomb repressor complexes in mammalian cells.
Nikolaj Dietrich, Mads Lerdrup, Eskild Landt, Shuchi Agrawal-Singh, Mads Bak, Niels Tommerup, Juri Rappsilber, Erik Södersten, Klaus Hansen
May 06, 2020
Polycomb Repressive Complex (PRC) 1 and PRC2 regulate genes involved in differentiation and development. However, the mechanism for how PRC1 and PRC2 are recruited to genes in mammalian cells is unclear. Here we present evidence...
Living in the Liminal: Representation of Transgender and Nonbinary Identity in 'Steven Universe'
Mads Bradley
Jan 01, 0001
An analysis of the children's animated series Steven Universe, this research takes a semiotic approach to explore anti-essentialist messages of gender identity. Atypical within the mainstream media, the cartoon expresses dynamic...
queer themes LGBTQ representation children's media cartoons Rebecca Sugar Adventure Time trans characters communication Feminist, Gender, and Sexuality Studies Film and Media Studies Lesbian, Gay, Bisexual, and Transgender Studies Television
Published by: Ursinus College
Hypo‐METRICS: Hypoglycaemia—MEasurement, ThResholds and ImpaCtS—A multi‐country clinical study to define the optimal threshold and duration of sensor‐detected hypoglycaemia that impact the experience of hypoglycaemia, quality of life and health economic outcomes
Patrick Divilly, Natalie Zaremba, Zeinab Mahmoudi, Uffe Søholm, Daniel J Pollard, Melanie Broadley, Evertine J Abbink, Bastiaan de Galan, Ulrik Pedersen‐Bjergaard, Eric Renard, Mark Evans, Jane Speight, Alan Brennan, Rory J McCrimmon, Matthias Müllenborn, Simon Heller, Alexander Seibold, Julia K Mader, Stephanie A Amiel, Frans Pouwer, Pratik Choudhary
Jun 29, 2022
Psychometric properties of an innovative smartphone application to investigate the daily impact of hypoglycemia in people with type 1 or type 2 diabetes
Uffe Søholm, Melanie Broadley, Natalie Zaremba, Patrick Divilly, Giesje Nefs, Jill Carlton, Julia K Mader, Petra Martina Baumann, Mikel Gomes, Gilberte Martine-Edith, Daniel J Pollard, Dajana Rath, Simon Heller, Ulrik Pedersen-Bjergaard, Rory J McCrimmon, Eric Renard, Mark Evans, Bastiaan de Galan, Thomas Forkmann, Stephanie A Amiel, Christel Hendrieckx, Jane Speight, Pratik Choudhary, Frans Pouwer
Apr 17, 2023
Introduction
The aim of this study was to determine the acceptability and psychometric properties of the Hypo-METRICS (Hypoglycemia MEasurement, ThResholds and ImpaCtS) application (app): a novel tool designed to assess...
Humans Diabetes mellitus Type 1 Diabetes mellitus Type 2 Hypoglycemia Insulin Reproducibility of Results Psychometrics Adult Aged Middle Aged Benchmarking Mobile Applications Smartphone Surveys and Questionnaires
Published by: PLOS ONE
Psychometric properties of an innovative smartphone application to investigate the daily impact of hypoglycemia in people with type 1 or type 2 diabetes
Introduction
The aim of this study was to determine the acceptability and psychometric properties of the Hypo-METRICS (Hypoglycemia MEasurement, ThResholds and ImpaCtS)...
Uffe Søholm, Melanie Broadley, Natalie Zaremba, Patrick Divilly, Giesje Nefs, Jill Carlton, Julia K Mader, Petra Martina Baumann, Mikel Gomes, Gilberte Martine-Edith, Daniel J Pollard, Dajana Rath, Simon Heller, Ulrik Pedersen-Bjergaard, Rory J McCrimmon, Eric Renard, Mark Evans, Bastiaan de Galan, Thomas Forkmann, Stephanie A Amiel, Christel Hendrieckx, Jane Speight, Pratik Choudhary, Frans Pouwer
Mar 17, 2023
A capped optimal stopping problem for the maximum process
This paper concerns an optimal stopping problem driven by the running maximum of a spectrally negative Lévy process X. More precisely, we are interested in capped versions of the American lookback optimal stopping problem...
Divergence of regulatory networks governed by the orthologous transcription factors FLC and PEP1 in Brassicaceae species.
Julieta L Mateos, Vicky Tilmes, Pedro Madrigal, Edouard Severing, René Richter, Colin WM Rijkenberg, Paweł Krajewski, George Coupland
Jun 19, 2020
Genome-wide landscapes of transcription factor (TF) binding sites (BSs) diverge during evolution, conferring species-specific transcriptional patterns. The rate of divergence varies in different metazoan lineages but has not...
Arabidopsis Arabis alpina binding-site evolution flowering vernalization Arabidopsis Proteins Binding Sites Brassicaceae Environment Flowers Gene Expression Regulation Plant Gene Regulatory Networks Gene-Environment Interaction genetic variation MADS Domain Proteins Nucleotide Motifs Plant Proteins Protein Binding Sequence Analysis DNA Transcription Factors
Rat pancreatectomy combined with isoprenaline or uninephrectomy as models of diabetic cardiomyopathy or nephropathy
Louise Thisted, Mette V. Østergaard, Annemarie A. Pedersen, Philip J. Pedersen, Ross T. Lindsay, Andrew J. Murray, Lisbeth N. Fink, Tanja X. Pedersen, Thomas Secher, Thea T. Johansen, Sebastian T. Thrane, Torben Skarsfeldt, Jacob Jelsing, Morten B. Thomsen, Nora E. Zois
Oct 01, 2021
Abstract: Cardiovascular and renal complications are the predominant causes of morbidity and mortality amongst patients with diabetes. Development of novel treatments have been hampered by the lack of available animal models...
RNA-Seq Time Series of Vitis vinifera Bud Development Reveals Correlation of Expression Patterns with the Local Temperature Profile.
Boas Pucker, Anna Schwandner, Sarah Becker, Ludger Hausmann, Prisca Viehöver, Reinhard Töpfer, Bernd Weisshaar, Daniela Holtgräwe
Nov 13, 2020
Plants display sophisticated mechanisms to tolerate challenging environmental conditions and need to manage their ontogenesis in parallel. Here, we set out to generate an RNA-Seq time series dataset throughout grapevine (Vitis...
Rat pancreatectomy combined with isoprenaline or uninephrectomy as models of diabetic cardiomyopathy or nephropathy
Louise Thisted, Mette V. Østergaard, Annemarie A. Pedersen, Philip J. Pedersen, Ross T. Lindsay, Andrew J. Murray, Lisbeth N. Fink, Tanja X. Pedersen, Thomas Secher, Thea T. Johansen, Sebastian T. Thrane, Torben Skarsfeldt, Jacob Jelsing, Morten B. Thomsen, Nora E. Zois
Sep 30, 2020
Abstract: Cardiovascular and renal complications are the predominant causes of morbidity and mortality amongst patients with diabetes. Development of novel treatments have been hampered by the lack of available animal models...
Rat pancreatectomy combined with isoprenaline or uninephrectomy as models of diabetic cardiomyopathy or nephropathy.
Louise Thisted, Mette V Østergaard, Annemarie A Pedersen, Philip J Pedersen, Ross T Lindsay, Andrew J Murray, Lisbeth N Fink, Tanja X Pedersen, Thomas Secher, Thea T Johansen, Sebastian T Thrane, Torben Skarsfeldt, Jacob Jelsing, Morten B Thomsen, Nora E Zois
Dec 04, 2020
Cardiovascular and renal complications are the predominant causes of morbidity and mortality amongst patients with diabetes. Development of novel treatments have been hampered by the lack of available animal models...
A capped optimal stopping problem for the maximum process
This paper concerns an optimal stopping problem driven by the running maximum of a spectrally negative Lévy process X. More precisely, we are interested in capped versions of the American lookback optimal stopping problem...
A 5700 year-old human genome and oral microbiome from chewed birch pitch.
Theis ZT Jensen, Jonas Niemann, Katrine Højholt Iversen, Anna K Fotakis, Shyam Gopalakrishnan, Åshild J Vågene, Mikkel Winther Pedersen, Mikkel-Holger S Sinding, Martin R Ellegaard, Morten E Allentoft, Liam T Lanigan, Alberto J Taurozzi, Sofie Holtsmark Nielsen, Michael W Dee, Martin N Mortensen, Mads C Christensen, Søren A Sørensen, Matthew J Collins, M Thomas P Gilbert, Martin Sikora, Simon Rasmussen, Hannes Schroeder
Feb 13, 2020
The rise of ancient genomics has revolutionised our understanding of human prehistory but this work depends on the availability of suitable samples. Here we present a complete ancient human genome and oral microbiome sequenced...
A theoretical analysis of taxonomic binning accuracy.
Many metagenomic and environmental DNA studies require the taxonomic assignment of individual reads or sequences by aligning reads to a reference database, known as taxonomic binning. When a read aligns to more than one...
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