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Results: 56
Metabolic phenotyping reveals a reduction in the bioavailability of serotonin and kynurenine pathway metabolites in both the urine and serum of individuals living with Alzheimer's disease.
Luke Whiley, Katie E Chappell, Ellie D'Hondt, Matthew R Lewis, Beatriz Jiménez, Stuart G Snowden, Hilkka Soininen, Iwona Kłoszewska, Patrizia Mecocci, Magda Tsolaki, Bruno Vellas, Jonathan R Swann, Abdul Hye, Simon Lovestone, Cristina Legido-Quigley, Elaine Holmes, AddNeuroMed consortium
Jan 09, 2021
A Pathway Based Classification Method for Analyzing Gene Expression for Alzheimer's Disease Diagnosis.
Nicola Voyle, Aoife Keohane, Stephen Newhouse, Katie Lunnon, Caroline Johnston, Hilkka Soininen, Iwona Kloszewska, Patrizia Mecocci, Magda Tsolaki, Bruno Vellas, Simon Lovestone, Angela Hodges, Steven Kiddle, Richard JB Dobson
Jun 11, 2018
BACKGROUND: Recent studies indicate that gene expression levels in blood may be able to differentiate subjects with Alzheimer's disease (AD) from normal elderly controls and mild cognitively impaired (MCI) subjects. However...
Indices of linguistic presentation in Romanian texts of the sixteenth century
Margareta Manu Magda
May 23, 2014
The paper aims to identify certain markers of the semantic-pragmatic category of linguistic presentation in the Romanian documents and records of the 16th century. The theoretical framework consists of Discourse Analysis and...
Published by: Atlantic Provinces Linguistic Association
Indices of linguistic presentation in Romanian texts of the sixteenth century
Margareta Manu Magda
May 23, 2014
The paper aims to identify certain markers of the semantic-pragmatic category of linguistic presentation in the Romanian documents and records of the 16th century. The theoretical framework consists of Discourse Analysis and...
linguistic presentation presentatives of existence identification and narration argumentation presentatives focalisation presentatives
Published by: Atlantic Provinces Linguistic Association
Genetic predisposition to increased blood cholesterol and triglyceride lipid levels and risk of Alzheimer disease
Petroula Proitsi, Michelle K Lupton, Latha Velayudhan, Stephen Newhouse, Isabella Fogh, Magda Tsolaki, Makrina Daniilidou, Megan Pritchard, Iwona Kloszewska, Hilkka Soininen, Patrizia Mecocci, Bruno Vellas, Alzheimer's Disease Neuroimaging Initiative, Julie Williams, GERAD1 Consortium, Robert Stewart, Pak Sham, Simon Lovestone, John F Powell
Nov 08, 2018
BACKGROUND: Although altered lipid metabolism has been extensively implicated in the pathogenesis of Alzheimer disease (AD) through cell biological, epidemiological, and genetic studies, the molecular mechanisms linking...
Relevance Theory and Translation
Linguistic theory and translation theory both deal with language; however, they rarely meet or use each other's results in order to advance their individual areas of research. Linguists often seem to look at translation as...
Published by: Atlantic Provinces Linguistic Association
Circulating Proteomic Signatures of Chronological Age.
Cristina Menni, Steven J Kiddle, Massimo Mangino, Ana Viñuela, Maria Psatha, Claire Steves, Martina Sattlecker, Alfonso Buil, Stephen Newhouse, Sally Nelson, Stephen Williams, Nicola Voyle, Hilkka Soininen, Iwona Kloszewska, Patrizia Mecocci, Magda Tsolaki, Bruno Vellas, Simon Lovestone, Tim D Spector, Richard Dobson, Ana M Valdes
Jun 11, 2018
To elucidate the proteomic features of aging in plasma, the subproteome targeted by the SOMAscan assay was profiled in blood samples from 202 females from the TwinsUK cohort. Findings were replicated in 677 independent...
aging Aptamers. Blood biomarkers early development Nucleotide Proteomics Adult Aged Aged 80 and over aging Biomarkers Carrier Proteins Cohort Studies Cytokines Eye Proteins Female Humans Insulin-Like Growth Factor Binding Protein 6 Male Matrix Metalloproteinase 12 Middle Aged Nerve Tissue Proteins Phenotype Proteomics Registries Twins United Kingdom
Relevance Theory and Translation
Linguistic theory and translation theory both deal with language; however, they rarely meet or use each other's results in order to advance their individual areas of research. Linguists often seem to look at translation as...
Published by: Atlantic Provinces Linguistic Association
Can Empathy Promote Cooperation When Status and Money Matter?
In the present study we ask, Does empathy also support cooperative behaviors when the status (high, low) of an individual differs relative to other group members and is determined by either chance or effort? In response to...
Can Empathy Promote Cooperation When Status and Money Matter?
In the present study we ask, Does empathy also support cooperative behaviors when the status (high, low) of an individual differs relative to other group members and is determined by either chance or effort? In response to...
Parenting and child mental health during the COVID-19 pandemic
COVID-19 and the subsequent public health response created many additional stresses for families. We examined parental behaviour during the COV-ID-19 pandemic in two European Countries and explored the association between...
child’s anxiety child’s quality of life covid-19 Parenting /dk/atira/pure/subjectarea/asjc/2700/2735 name=Pediatrics, Perinatology, and Child Health /dk/atira/pure/subjectarea/asjc/3200/3205 name=Experimental and Cognitive Psychology /dk/atira/pure/subjectarea/asjc/3200/3204 name=Developmental and Educational Psychology /dk/atira/pure/subjectarea/asjc/3200/3203 name=Clinical Psychology /dk/atira/pure/subjectarea/asjc/2700/2738 name=Psychiatry and Mental health /dk/atira/pure/sustainabledevelopmentgoals/good_health_and_well_being name=SDG 3 - Good Health and Well-being
Parenting and child mental health during the COVID-19 pandemic
COVID-19 and the subsequent public health response created many additional stresses for families. We examined parental behaviour during the COV-ID-19 pandemic in two European Countries and explored the association between...
child’s anxiety child’s quality of life covid-19 Parenting /dk/atira/pure/subjectarea/asjc/2700/2735 name=Pediatrics, Perinatology, and Child Health /dk/atira/pure/subjectarea/asjc/3200/3205 name=Experimental and Cognitive Psychology /dk/atira/pure/subjectarea/asjc/3200/3204 name=Developmental and Educational Psychology /dk/atira/pure/subjectarea/asjc/3200/3203 name=Clinical Psychology /dk/atira/pure/subjectarea/asjc/2700/2738 name=Psychiatry and Mental health /dk/atira/pure/sustainabledevelopmentgoals/good_health_and_well_being name=SDG 3 - Good Health and Well-being
Guided assembly of cancer ellipsoid on suspended hydrogel microfibers estimates multi-cellular traction force
Cheng-Tai Lee, Elisabeth L Gill, Wenyu Wang, Magda Gerigk, Eugene M Terentjev, Yan Yan Shery Huang
Mar 10, 2021
Abstract: Three-dimensional (3D) multi-cellular aggregates hold important applications in tissue engineering and in vitro biological modeling. Probing the intrinsic forces generated during the aggregation process, could open up...
Guided assembly of cancer ellipsoid on suspended hydrogel microfibers estimates multi-cellular traction force
Cheng-Tai Lee, Elisabeth L Gill, Wenyu Wang, Magda Gerigk, Eugene M Terentjev, Yan Yan Shery Huang
Mar 10, 2021
Abstract: Three-dimensional (3D) multi-cellular aggregates hold important applications in tissue engineering and in vitro biological modeling. Probing the intrinsic forces generated during the aggregation process, could open up...
Fabrication of Designable and Suspended Microfibers via Low-Voltage 3D Micropatterning.
Elisabeth L Gill, Samuel Willis, Magda Gerigk, Paul Cohen, Duo Zhang, Xia Li, Yan Yan Shery Huang
Jun 28, 2019
Electrotherapies for Glioblastoma.
Elise PW Jenkins, Alina Finch, Magda Gerigk, Iasonas F Triantis, Colin Watts, George G Malliaras
Jun 08, 2021
Non-thermal, intermediate frequency (100-500 kHz) electrotherapies present a unique therapeutic strategy to treat malignant neoplasms. Here, pulsed electric fields (PEFs) which induce reversible or irreversible electroporation...
Carbon neutral manufacturing via on-site CO2 recycling.
The chemical industry needs to significantly decrease carbon dioxide (CO2) emissions in order to meet the 2050 carbon neutrality goal. Utilization of CO2 as a chemical feedstock for bulk products is a promising way to mitigate...
Guided assembly of cancer ellipsoid on suspended hydrogel microfibers estimates multi-cellular traction force.
Cheng-Tai Lee, Elisabeth L Gill, Wenyu Wang, Magda Gerigk, Eugene M Terentjev, Yan Yan Shery Huang
Jan 28, 2022
Image-Assisted Microvessel-on-a-Chip Platform for Studying Cancer Cell Transendothelial Migration Dynamics.
Cristina Bertulli, Magda Gerigk, Nicholas Piano, Ye Liu, Duo Zhang, Thomas Müller, Tuomas J Knowles, Yan Yan Shery Huang
Oct 03, 2018
With the push to reduce in vivo approaches, the demand for microphysiological models that recapitulate the in vivo settings in vitro is dramatically increasing. Here, we present an extracellular matrix-integrated microfluidic...
Cumulative Risk Exposure and Social Isolation as Correlates of Carer and Child Mental Health During the COVID-19 Pandemic
Ana Isabel Pereira, Peter Muris, Magda Sofia Roberto, Paul Stallard, Luis Joaquin Garcia-Lopez, Bogdan Tudor Tulbure, Ioana Podina, Ellin Simon, Marlene Sousa, Luísa Barros
Feb 28, 2023
This study adopted a cumulative risk approach to examine the relations between various domains of risk factors (i.e., social isolation and home confinement, other pandemic-related risk factors, and pre-existing psychosocial...
children adolescents and carers covid-19 Mental Health Pre-existing psychosocial risks Social isolation and home confinement /dk/atira/pure/subjectarea/asjc/2700/2735 name=Pediatrics, Perinatology, and Child Health /dk/atira/pure/subjectarea/asjc/3200/3204 name=Developmental and Educational Psychology /dk/atira/pure/subjectarea/asjc/2700/2738 name=Psychiatry and Mental health /dk/atira/pure/sustainabledevelopmentgoals/good_health_and_well_being name=SDG 3 - Good Health and Well-being
Inflammatory biomarkers in Alzheimer's disease plasma.
Angharad R Morgan, Samuel Touchard, Claire Leckey, Caroline O'Hagan, Alejo J Nevado-Holgado, NIMA Consortium, Frederik Barkhof, Lars Bertram, Olivier Blin, Isabelle Bos, Valerija Dobricic, Sebastiaan Engelborghs, Giovanni Frisoni, Lutz Frölich, Silvey Gabel, Peter Johannsen, Petronella Kettunen, Iwona Kłoszewska, Cristina Legido-Quigley, Alberto Lleó, Pablo Martinez-Lage, Patrizia Mecocci, Karen Meersmans, José Luis Molinuevo, Gwendoline Peyratout, Julius Popp, Jill Richardson, Isabel Sala, Philip Scheltens, Johannes Streffer, Hikka Soininen, Mikel Tainta-Cuezva, Charlotte Teunissen, Magda Tsolaki, Rik Vandenberghe, Pieter Jelle Visser, Stephanie Vos, Lars-Olof Wahlund, Anders Wallin, Sarah Westwood, Henrik Zetterberg, Simon Lovestone, B Paul Morgan, Annex: NIMA–Wellcome Trust Consortium for Neuroimmunology of Mood Disorders and Alzheimer's Disease
Jul 23, 2019
INTRODUCTION: Plasma biomarkers for Alzheimer's disease (AD) diagnosis/stratification are a "Holy Grail" of AD research and intensively sought; however, there are no well-established plasma markers. METHODS: A hypothesis-led...
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