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T cell studies in a peptide-induced model of systemic lupus erythematosus
We have previously reported that immunization with a peptide mimetope of dsDNA on a branched polylysine backbone (DWEYSVWLSN-MAP) induces a systemic lupus erythematosus-like syndrome in the nonautoimmune BALB/c mouse strain. To...
Published by: Rockefeller University
Student perspectives of preparedness characteristics for clinical learning within a fully distributed veterinary teaching model.
The transition into the clinical environment is challenging and associated with significant stress and anxiety. This study aimed to examine the perspectives of students on the characteristics important for preparedness for...
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Mitochondrial Dysfunction Increases Arrhythmic Triggers and Substrates; Potential Anti-arrhythmic Pharmacological Targets.
Incidence of cardiac arrhythmias increases significantly with age. In order to effectively stratify arrhythmic risk in the aging population it is crucial to elucidate the relevant underlying molecular mechanisms. The changes...
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Student perspectives of preparedness characteristics for clinical learning within a fully distributed veterinary teaching model
The transition into the clinical environment is challenging and associated with significant stress and anxiety. This study aimed to examine the perspectives of students on the characteristics important for preparedness for...
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Anti-malarial drugs
Malaria remains the leading cause of parasitic death in the world. Artemisinin resistance is an emerging threat indicating an imminent need for novel combination therapy. Given the key role of mass drug administration, it is...
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Financial Development and Economic Growth Nexus in the South Mediterranean Countries (SMCs)
Khalil Mhadhbi
Jan 01, 2022
This article investigates the presence of asymmetries in the short- and long-run relationships between financial development and economic growth covering four SMCs from 1984 to 2017 by applying the nonlinear ARDL. We factored...
Gender Depictions in TV Advertising in the Gulf
Ali Khalil
Jan 01, 2024
This content analysis examines gender portrayal in advertisements in television advertising in the GCC, and contrasts those depictions with the results of an earlier study of the same region. Analysis revealed that stereotypical...
Family Businesses and Their Transition to Industry 4.0
Industry 4.0 (I4.0) is the new paradigm shift impacting businesses today. This study explores the state of Bangladeshi family businesses in adapting to I4.0 using a qualitative research methodology. Top management personnel were...
Microglia Diversity in Health and Multiple Sclerosis.
Multiple Sclerosis (MS) is a neurodegenerative disease characterized by multiple focal lesions, ongoing demyelination and, for most people, a lack of remyelination. MS lesions are enriched with monocyte-derived macrophages and...
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Transcriptional profiles of genes related to electrophysiological function in Scn5a+/- murine hearts.
The Scn5a gene encodes the major pore-forming Nav 1.5 (α) subunit, of the voltage-gated Na+ channel in cardiomyocytes. The key role of Nav 1.5 in action potential initiation and propagation in both atria and ventricles...
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Molecular basis of arrhythmic substrate in ageing murine peroxisome proliferator-activated receptor γ co-activator deficient hearts modelling mitochondrial dysfunction.
INTRODUCTION:Ageing and chronic metabolic disorders are associated with mitochondrial dysfunction and cardiac pro-arrhythmic phenotypes which were recently attributed to slowed atrial and ventricular action potential (AP)...
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