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Results: 1076
Leukotriene A4 Hydrolase Genotype and HIV Infection Influence Intracerebral Inflammation and Survival From Tuberculous Meningitis.
Nguyen TT Thuong, Dorothee Heemskerk, Trinh TB Tram, Le TP Thao, Lalita Ramakrishnan, Vu TN Ha, Nguyen D Bang, Tran TH Chau, Nguyen H Lan, Maxine Caws, Sarah J Dunstan, Nguyen VV Chau, Marcel Wolbers, Nguyen TH Mai, Guy E Thwaites
Nov 21, 2018
BACKGROUND: Tuberculous meningitis (TBM) is the most devastating form of tuberculosis, yet very little is known about the pathophysiology. We hypothesized that the genotype of leukotriene A4 hydrolase (encoded by LTA4H), which...
Leukotriene A4 hydrolase genotype Cytokines inflammatory response survival. Tuberculous meningitis Adolescent Adult Aged Aged 80 and over Antiretroviral Therapy Highly Active Antitubercular Agents Cerebrum Cytokines Epoxide Hydrolases Female Genotype HIV Infections Humans Inflammation Kaplan-Meier Estimate Leukocytes Male Middle Aged Multivariate Analysis Mycobacterium tuberculosis Polymorphism Single Nucleotide Proportional Hazards Models Survival Analysis Tuberculosis Meningeal Young Adult
SARS-CoV-2 Papain-Like Protease Potential Inhibitors-In Silico Quantitative Assessment.
Adam Stasiulewicz, Alicja W Maksymiuk, Mai Lan Nguyen, Barbara Bełza, Joanna I Sulkowska
Apr 13, 2021
Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) encodes the papain-like protease (PLpro). The protein not only plays an essential role in viral replication but also cleaves ubiquitin and ubiquitin-like...
covid-19 PLpro SARS-CoV-2 UCH-L1 coronavirus docking papain-like protease pharmacophore Virtual screening Animals Antiviral Agents Computer Simulation Coronavirus Papain-Like Proteases Crystallography X-Ray Databases Chemical Databases Protein Drug Evaluation Preclinical Humans Inhibitory Concentration 50 Lethal Dose 50 Ligands Mutagenicity Tests Protease Inhibitors Quantitative Structure-Activity Relationship Rats SARS-CoV-2 Ubiquitin Thiolesterase
Prognostic models for 9 month mortality in tuberculous meningitis
Le Thi Phuong Thao, A Dorothee Heemskerk, Ronald B Geskus, Nguyen Thi Hoang Mai, Dang Thi Minh Ha, Tran Thi Hong Chau, Nguyen Hoan Phu, Nguyen Van Vinh Chau, Maxine Caws, Nguyen Huu Lan, Do Dang Anh Thu, Nguyen Thuy Thuong Thuong, Jeremy Day, Jeremy J Farrar, M Estee Torok, Nguyen Duc Bang, Guy E Thwaites, Marcel Wolbers
May 02, 2018
Dynamic Prediction of Death in Patients With Tuberculous Meningitis Using Time-updated Glasgow Coma Scale and Plasma Sodium Measurements.
Le Thi Phuong Thao, Marcel Wolbers, A Dorothee Heemskerk, Nguyen Thi Hoang Mai, Dang Thi Minh Ha, Tran Thi Hong Chau, Nguyen Hoan Phu, Nguyen Van Vinh Chau, Maxine Caws, Nguyen Huu Lan, Do Dang Anh Thu, Nguyen Thuy Thuong Thuong, Jeremy Day, M Estee Torok, Nguyen Duc Bang, Guy E Thwaites, Ronald B Geskus
Apr 16, 2019
Amino acid variants of SARS-CoV-2 papain-like protease have impact on drug binding.
Agata P Perlinska, Adam Stasiulewicz, Mai Lan Nguyen, Karolina Swiderska, Mikolaj Zmudzinski, Alicja W Maksymiuk, Marcin Drag, Joanna I Sulkowska
Dec 08, 2022
The novel severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) has caused both a health and economic crisis around the world. Its papain-like protease (PLpro) is one of the protein targets utilized in designing new drugs...
The Control of Typhoid Fever in Vietnam.
Tran Vu Thieu Nga, Pham Thanh Duy, Nguyen Phu Huong Lan, Nguyen Van Vinh Chau, Stephen Baker
Apr 10, 2019
Typhoid fever, caused by Salmonella enterica serovar Typhi (S. Typhi), is a diminishing public health problem in Vietnam, and this process may represent a prototype for typhoid elimination in Asia. Here, we review typhoid...
Forager and farmer evolutionary adaptations to malaria evidenced by 7000 years of thalassemia in Southeast Asia.
Melandri Vlok, Hallie R Buckley, Justyna J Miszkiewicz, Meg M Walker, Kate Domett, Anna Willis, Hiep H Trinh, Tran T Minh, Mai Huong T Nguyen, Lan Cuong Nguyen, Hirofumi Matsumura, Tianyi Wang, Huu T Nghia, Marc F Oxenham
Mar 11, 2021
Amino acid variants of SARS-CoV-2 papain-like protease have impact on drug binding.
Agata P Perlinska, Adam Stasiulewicz, Mai Lan Nguyen, Karolina Swiderska, Mikolaj Zmudzinski, Alicja W Maksymiuk, Marcin Drag, Joanna I Sulkowska
Dec 22, 2022
The novel severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) has caused both a health and economic crisis around the world. Its papain-like protease (PLpro) is one of the protein targets utilized in designing new drugs...
Invasive Non-typhoidal Salmonella Infections in Asia
Nguyen Phu Huong Lan, Tu Le Thi Phuong, Hien Nguyen Huu, Le Thuy, Alison E Mather, Se Eun Park, Florian Marks, Guy E Thwaites, Nguyen Van Vinh Chau, Corinne N Thompson, Stephen Baker
Feb 19, 2019
Invasive non-typhoidal Salmonella (iNTS) infections are now a well-described cause of morbidity and mortality in children and HIV-infected adults in sub-Saharan Africa. In contrast, the epidemiology and clinical manifestations...
Adult Aged Anti-Infective Agents Ceftriaxone Drug Therapy Combination Female Fluoroquinolones HIV Infections Hospitals Humans Logistic Models Male Middle Aged Multilocus Sequence Typing Multivariate Analysis Retrospective Studies Salmonella Infections Salmonella enterica Serogroup Sex Factors Trimethoprim Sulfamethoxazole Drug Combination Typhoid Fever Vietnam
The Impact of Corporate Social Responsibility Performance on Competitive Advantage and Business Success
This study investigates how types of corporate social responsibility (CSR) practices (economic, legal, ethical, philanthropic, and environmental) affect competitive advantage and business success in an emerging country. Data...
Published by: IGI Global Scientific Publishing
Does Inflation Affect Emissions Reduction?
Inflation and sustainable development are two important factors in the economic development of most countries. This study will use empirical analysis to examine how macroeconomic variables, including the money supply (M2)...
Published by: IGI Global Scientific Publishing
Deep Learning Forwarding in NDN With a Case Study of Ethernet LAN
In this paper, the authors propose a novel forwarding strategy based on deep learning that can adaptively route interests/data packets through ethernet links without relying on the FIB table. The experiment was conducted as a...
Published by: IGI Global Scientific Publishing
Limited contribution of non-intensive chicken farming to ESBL-producing Escherichia coli colonization in humans in Vietnam
Vinh Trung Nguyen, Dorota Jamrozy, Sébastien Matamoros, Juan J Carrique-Mas, Huynh Mai Ho, Quoc Hieu Thai, Thi Nhu Mai Nguyen, Jaap A Wagenaar, Guy Thwaites, Julian Parkhill, Constance Schultsz, Thi Hoa Ngo
Aug 20, 2019
OBJECTIVES: To investigate the risk of colonization with ESBL-producing Escherichia coli (ESBL-Ec) in humans in Vietnam associated with non-intensive chicken farming. METHODS: Faecal samples from 204 randomly selected farmers...
Whether English Proficiency and English Self-Efficacy Influence the Credibility of ChatGPT-Generated English Content of EMI Students
This study investigated whether English proficiency (EP) and English self-efficacy (ESE) influence the credibility of ChatGPT-generated English content (CCGEC) of college students in the English-medium instruction (EMI) courses....
Published by: IGI Global Scientific Publishing
Genomic surveillance for hypervirulence and multi-drug resistance in invasive Klebsiella pneumoniae from South and Southeast Asia.
Kelly L Wyres, To N T Nguyen, Margaret M C Lam, Louise M Judd, Nguyen Van Vinh Chau, David A B Dance, Margaret Ip, Abhilasha Karkey, Clare L Ling, Thyl Miliya, Paul N Newton, Nguyen Phu Huong Lan, Amphone Sengduangphachanh, Paul Turner, Balaji Veeraraghavan, Phat Voong Vinh, Manivanh Vongsouvath, Nicholas R Thomson, Stephen Baker, Kathryn E Holt
Feb 19, 2020
BACKGROUND:Klebsiella pneumoniae is a leading cause of bloodstream infection (BSI). Strains producing extended-spectrum beta-lactamases (ESBLs) or carbapenemases are considered global priority pathogens for which new treatment...
Published by: Genome medicine
Genomic surveillance for hypervirulence and multi-drug resistance in invasive Klebsiella pneumoniae from South and Southeast Asia.
Kelly L Wyres, To NT Nguyen, Margaret MC Lam, Louise M Judd, Nguyen Van Vinh Chau, David AB Dance, Margaret Ip, Abhilasha Karkey, Clare L Ling, Thyl Miliya, Paul N Newton, Nguyen Phu Huong Lan, Amphone Sengduangphachanh, Paul Turner, Balaji Veeraraghavan, Phat Voong Vinh, Manivanh Vongsouvath, Nicholas R Thomson, Stephen Baker, Kathryn E Holt
Mar 02, 2020
BACKGROUND: Klebsiella pneumoniae is a leading cause of bloodstream infection (BSI). Strains producing extended-spectrum beta-lactamases (ESBLs) or carbapenemases are considered global priority pathogens for which new treatment...
Anticaries and antimicrobial activities of methanolic extract from leaves of <i>Cleistocalyx operculatus</i> L.
Phuong Thi Mai Nguyen, Nadin Schultze, Christian Boger, Zeyad Alresley, Albert Bolhuis, Ulrike Lindequist
Jan 01, 2017
Objective: To investigate antimicrobial activities of methanolic extract of leaves of Cleistocalyx operculatus L. (C. operculatus) grown in Vietnam.
Methods: The methanolic extract of C. operculatus leaves was...
Methods: The methanolic extract of C. operculatus leaves was...
Anticaries and antimicrobial activities of methanolic extract from leaves of <i>Cleistocalyx operculatus</i> L.
Phuong Thi Mai Nguyen, Nadin Schultze, Christian Boger, Zeyad Alresley, Albert Bolhuis, Ulrike Lindequist
Jan 01, 2017
Objective: To investigate antimicrobial activities of methanolic extract of leaves of Cleistocalyx operculatus L. (C. operculatus) grown in Vietnam.
Methods: The methanolic extract of C. operculatus leaves was...
Methods: The methanolic extract of C. operculatus leaves was...
Erythrocytes lacking the Langereis blood group protein ABCB6 are resistant to the malaria parasite Plasmodium falciparum.
Elizabeth S Egan, Michael P Weekes, Usheer Kanjee, Jale Manzo, Ashwin Srinivasan, Christine Lomas-Francis, Connie Westhoff, Junko Takahashi, Mitsunobu Tanaka, Seishi Watanabe, Carlo Brugnara, Steven P Gygi, Yoshihiko Tani, Manoj T Duraisingh
Jun 25, 2018
The ATP-binding cassette transporter ABCB6 was recently discovered to encode the Langereis (Lan) blood group antigen. Lan null individuals are asymptomatic, and the function of ABCB6 in mature erythrocytes is not understood....
Differential prevalence and geographic distribution of hepatitis C virus genotypes in acute and chronic hepatitis C patients in Vietnam.
Chau Le Ngoc, Thanh Tran Thi Thanh, Phuong Tran Thi Lan, Trinh Nguyen Mai, Trang Nguyen Hoa, Ngoc Nghiem My, Tan Le Van, Hung Le Manh, Phuong Le Thanh, Chau Nguyen Van Vinh, Guy Thwaites, Graham Cooke, Gabrielle M Heilek, Cecilia Shikuma, Thuy Le, Stephen Baker, Motiur Rahman, VIZIONS consortium
Apr 10, 2019
BACKGROUND: The highest burden of disease from hepatitis C virus (HCV) is found in Southeast Asia, but our understanding of the epidemiology of infection in many heavily burdened countries is still limited. In particular, there...
Genomic surveillance for hypervirulence and multi-drug resistance in invasive Klebsiella pneumoniae from South and Southeast Asia
Kelly L. Wyres, To N. T. Nguyen, Margaret M. C. Lam, Louise M. Judd, Nguyen Van Vinh Chau, David A. B. Dance, Margaret Ip, Abhilasha Karkey, Clare L. Ling, Thyl Miliya, Paul N. Newton, Nguyen Phu Huong Lan, Amphone Sengduangphachanh, Paul Turner, Balaji Veeraraghavan, Phat Voong Vinh, Manivanh Vongsouvath, Nicholas R. Thomson, Stephen Baker, Kathryn E. Holt
Jan 15, 2021
Abstract: Background: Klebsiella pneumoniae is a leading cause of bloodstream infection (BSI). Strains producing extended-spectrum beta-lactamases (ESBLs) or carbapenemases are considered global priority pathogens for which new...
Genomic surveillance for hypervirulence and multi-drug resistance in invasive Klebsiella pneumoniae from South and Southeast Asia
Kelly L. Wyres, To N. T. Nguyen, Margaret M. C. Lam, Louise M. Judd, Nguyen Van Vinh Chau, David A. B. Dance, Margaret Ip, Abhilasha Karkey, Clare L. Ling, Thyl Miliya, Paul N. Newton, Nguyen Phu Huong Lan, Amphone Sengduangphachanh, Paul Turner, Balaji Veeraraghavan, Phat Voong Vinh, Manivanh Vongsouvath, Nicholas R. Thomson, Stephen Baker, Kathryn E. Holt
Jun 06, 2020
Abstract: Background: Klebsiella pneumoniae is a leading cause of bloodstream infection (BSI). Strains producing extended-spectrum beta-lactamases (ESBLs) or carbapenemases are considered global priority pathogens for which new...
Tumour microbiomes and Fusobacterium genomics in Vietnamese colorectal cancer patients.
Hoang NH Tran, Trang Nguyen Hoang Thu, Phu Huu Nguyen, Chi Nguyen Vo, Khanh Van Doan, Chau Nguyen Ngoc Minh, Ngoc Tuan Nguyen, Van Ngoc Duc Ta, Khuong An Vu, Thanh Danh Hua, To Nguyen Thi Nguyen, Tan Trinh Van, Trung Pham Duc, Ba Lap Duong, Phuc Minh Nguyen, Vinh Chuc Hoang, Duy Thanh Pham, Guy E Thwaites, Lindsay J Hall, Daniel J Slade, Stephen Baker, Vinh Hung Tran, Hao Chung The
Nov 28, 2022
Perturbations in the gut microbiome have been associated with colorectal cancer (CRC), with the colonic overabundance of Fusobacterium nucleatum shown as the most consistent marker. Despite its significance in the promotion of...
Excess body weight and age associated with the carriage of fluoroquinolone and third-generation cephalosporin resistance genes in commensal Escherichia coli from a cohort of urban Vietnamese children.
Le Thi Quynh Nhi, Ha Thanh Tuyen, Pham Duc Trung, Tran Do Hoang Nhu, Pham Thanh Duy, Chung The Hao, Nguyen Thi Thanh Nhan, Lu Lan Vi, Hoang Thi Diem Tuyet, Tran Thi Thuy Tien, Nguyen Van Vinh Chau, Phung Khanh Lam, Guy Thwaites, Stephen Baker
Apr 10, 2019
PURPOSE: Antimicrobial-resistant bacterial infections in low- and middle-income countries (LMICs) are a well-established global health issue. We aimed to assess the prevalence of and epidemiological factors associated with the...
EBSL Vietnam Antimicrobial resistance co-selection cohort Fluoroquinolones plasmid mediated quinolone resistance third generation cephalosporins Age Factors Anti-Bacterial Agents Body Weight Carrier State Child Preschool ciprofloxacin Drug Resistance Bacterial Escherichia coli Escherichia coli Infections Feces Female Fluoroquinolones Humans Male Microbial Sensitivity Tests Prospective Studies Vietnam
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