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Recommendations for the management of secondary hypogammaglobulinaemia due to B cell targeted therapies in autoimmune rheumatic diseases.
Sonali Wijetilleka, David R Jayne, Chetan Mukhtyar, Aftab Ala, Philip D Bright, Hector Chinoy, Lorraine Harper, Majid A Kazmi, Sorena Kiani-Alikhan, Charles K Li, Siraj A Misbah, Louise Oni, Fiona E Price-Kuehne, Alan D Salama, Sarita Workman, David Wrench, Mohammed Yousuf Karim
Nov 27, 2019
OBJECTIVES: The association of B cell targeted therapies with development of hypogammaglobulinaemia and infection is increasingly recognized. Our aim was to develop consensus recommendations for immunoglobulin replacement...
IMPACT OF EMERGING GEO-INFORMATICS TECHNOLOGIES IN CITY AND REGIONAL PLANNING OF PAKISTAN
Syed Jamil Hasan Kazmi
Dec 14, 2019
Geo-informatics is a term portraying the integral role of GIS, Remote Sensing, GPS and Surveying. The magic of this wonderful set of tools timely realized by the planners in developing and developed countries. Today...
Published by: Department of History, University of Karachi
Immunoglobulin replacement for secondary immunodeficiency after B-cell targeted therapies in autoimmune rheumatic disease
Sonali Wijetilleka, Chetan Mukhtyar, David Jayne, Aftab Ala, Philip Bright, Hector Chinoy, Lorraine Harper, Majid Kazmi, Sorena Kiani-Alikhan, Charles Li, Siraj Misbah, Louise Oni, Fiona Price-Kuehne, Alan Salama, Sarita Workman, David Wrench, Mohammed Yousuf Karim
Feb 24, 2020
BACKGROUND: Consensus guidelines are not available for the use of immunoglobulin replacement therapy (IGRT) in patients developing iatrogenic secondary antibody deficiency following B-cell targeted therapy (BCTT) in autoimmune...
Information Requirements Analysis for Holonic Manufacturing Systems in a Virtual Environment
The design and development of holonic manufacturing systems requires careful, and sometimes risky, decision making to ensure that they will successfully satisfy the demands of an ever-changing market. In this paper, the authors...
Information Requirements Analysis for Holonic Manufacturing Systems in a Virtual Environment
The design and development of holonic manufacturing systems requires careful, and sometimes risky, decision making to ensure that they will successfully satisfy the demands of an ever-changing market. In this paper, the authors...
Natural Biomaterials for Cardiac Tissue Engineering
Qasim A. Majid, Annabelle T. R. Fricker, David A. Gregory, Natalia Davidenko, Olivia Hernandez Cruz, Richard J. Jabbour, Thomas J. Owen, Pooja Basnett, Barbara Lukasiewicz, Molly Stevens, Serena Best, Ruth Cameron, Sanjay Sinha, Sian E. Harding, Ipsita Roy
Nov 09, 2020
Cardiovascular diseases (CVD) constitute a major fraction of the current major global diseases and lead to about 30% of the deaths, i.e., 17.9 million deaths per year. CVD include coronary artery disease (CAD), myocardial...
Millimeter-Wave-to-Terahertz Superconducting Plasmonic Waveguides for Integrated Nanophotonics at Cryogenic Temperatures.
Samane Kalhor, Majid Ghanaatshoar, Hannah J Joyce, David A Ritchie, Kazuo Kadowaki, Kaveh Delfanazari
Sep 27, 2021
Plasmonics, as a rapidly growing research field, provides new pathways to guide and modulate highly confined light in the microwave-to-optical range of frequencies. We demonstrated a plasmonic slot waveguide, at the nanometer...
Natural Biomaterials for Cardiac Tissue Engineering
Qasim A Majid, Annabelle TR Fricker, David A Gregory, Natalia Davidenko, Olivia Hernandez Cruz, Richard J Jabbour, Thomas J Owen, Pooja Basnett, Barbara Lukasiewicz, Molly Stevens, Serena Best, Ruth Cameron, Sanjay Sinha, Sian E Harding, Ipsita Roy
Nov 23, 2020
Cardiovascular diseases (CVD) constitute a major fraction of the current major global diseases and lead to about 30% of the deaths, i.e., 17.9 million deaths per year. CVD include coronary artery disease (CAD), myocardial...
High-flow nasal oxygen vs. standard oxygen therapy for patients undergoing transcatheter aortic valve replacement with conscious sedation
S Scheuermann, A Tan, P Govender, M Mckie, J Pack, G Martinez, F Falter, S George, A A. Klein
Apr 14, 2023
Millimeter-Wave-to-Terahertz Superconducting Plasmonic Waveguides for Integrated Nanophotonics at Cryogenic Temperatures
Samane Kalhor, Majid Ghanaatshoar, Hannah J. Joyce, David A. Ritchie, Kazuo Kadowaki, Kaveh Delfanazari
Aug 02, 2021
Plasmonics, as a rapidly growing research field, provides new pathways to guide and modulate highly confined light in the microwave-to-optical range of frequencies. We demonstrated a plasmonic slot waveguide, at the nanometer...
A Phase 2a cohort expansion study to assess the safety, tolerability, and preliminary efficacy of CXD101 in patients with advanced solid-organ cancer expressing HR23B or lymphoma
Stephen W. Booth, Toby A. Eyre, John Whittaker, Leticia Campo, Lai Mun Wang, Elizabeth Soilleux, Daniel Royston, Gabrielle Rees, Murali Kesavan, Catherine Hildyard, Farasat Kazmi, Nick La Thangue, David Kerr, Mark R. Middleton, Graham P. Collins
Jul 28, 2021
Diffusion-weighted magnetic resonance imaging to assess diffuse renal pathology
Anna Caroli, Moritz Schneider, Iris Friedli, Alexandra Ljimani, Sophie De Seigneux, Peter Boor, Latha Gullapudi, Isma Kazmi, Iosif A Mendichovszky, Mike Notohamiprodjo, Nicholas M Selby, Harriet C Thoeny, Nicolas Grenier, Jean-Paul Vallée
Sep 20, 2018
A Phase 2a cohort expansion study to assess the safety, tolerability, and preliminary efficacy of CXD101 in patients with advanced solid-organ cancer expressing HR23B or lymphoma.
Stephen W Booth, Toby A Eyre, John Whittaker, Leticia Campo, Lai Mun Wang, Elizabeth Soilleux, Daniel Royston, Gabrielle Rees, Murali Kesavan, Catherine Hildyard, Farasat Kazmi, Nick La Thangue, David Kerr, Mark R Middleton, Graham P Collins
Sep 24, 2021
BACKGROUND: This Phase 2a dose expansion study was performed to assess the safety, tolerability and preliminary efficacy of the maximum tolerated dose of the oral histone de-acetylase (HDAC) inhibitor CXD101 in patients with...
Attention Res-UNet
During a dermoscopy examination, accurate and automatic skin lesion detection and segmentation can assist medical experts in resecting problematic areas and decrease the risk of deaths due to skin cancer. In order to develop...
Published by: IGI Global Scientific Publishing
Analysis of Cloud Bursting on Openstack Infrastructure to AWS
Cloud computing is the development of distributed and parallel computing that seeks to provide a new model of business computing by automating services and efficiently storing proprietary data. Cloud bursting is one of the cloud...
OpenStack VM infrastructure private cloud public cloud cloud burst VM container Computer and Systems Architecture Computer Sciences Digital Communications and Networking
Published by: Harrisburg University of Science and Technology
An Ensemble Random Forest Algorithm for Privacy Preserving Distributed Medical Data Mining
As the voluminous amount of data is generated because of inexorably widespread proliferation of electronic data maintained using the Electronic Health Records (EHRs). Medical health facilities have great potential to discern the...
Published by: IGI Global Scientific Publishing
Achieving robustness to aleatoric uncertainty with heteroscedastic Bayesian optimisation
Ryan-Rhys Griffiths, Alexander A Aldrick, Miguel Garcia-Ortegon, Vidhi Lalchand, Alpha A Lee
Nov 23, 2021
Abstract: Bayesian optimisation is a sample-efficient search methodology that holds great promise for accelerating drug and materials discovery programs. A frequently-overlooked modelling consideration in Bayesian optimisation...
Low defect and high electrical conductivity of graphene through plasma graphene healing treatment monitored with in situ optical emission spectroscopy.
Mohammad Salehi, Parnia Bastani, Loghman Jamilpanah, Abbas Madani, Seyed Majid Mohseni, Babak Shokri
Oct 13, 2021
Fundamental studies on graphene (Gr) and its real device applications have been affected by unavoidable defects and impurities which are usually present in synthesized Gr. Therefore, post treatment methods on Gr have been an...
Active Terahertz Modulator and Slow Light Metamaterial Devices with Hybrid Graphene–Superconductor Photonic Integrated Circuits
Samane Kalhor, Stephen J. Kindness, Robert Wallis, Harvey E. Beere, Majid Ghanaatshoar, Riccardo Degl′Innocenti, Michael J. Kelly, Stephan Hofmann, Hannah J. Joyce, David A. Ritchie, Kaveh Delfanazari
Nov 12, 2021
Metamaterial photonic integrated circuits with arrays of hybrid graphene–superconductor coupled split-ring resonators (SRR) capable of modulating and slowing down terahertz (THz) light are introduced and proposed. The hybrid...
A Phase 2a cohort expansion study to assess the safety, tolerability, and preliminary efficacy of CXD101 in patients with advanced solid-organ cancer expressing HR23B or lymphoma.
Stephen W Booth, Toby A Eyre, John Whittaker, Leticia Campo, Lai Mun Wang, Elizabeth Soilleux, Daniel Royston, Gabrielle Rees, Murali Kesavan, Catherine Hildyard, Farasat Kazmi, Nick La Thangue, David Kerr, Mark R Middleton, Graham P Collins
Aug 26, 2021
Background
This Phase 2a dose expansion study was performed to assess the safety, tolerability and preliminary efficacy of the maximum tolerated dose of the oral histone de-acetylase (HDAC) inhibitor CXD101 in patients...
Published by: BMC cancer
Active Terahertz Modulator and Slow Light Metamaterial Devices with Hybrid Graphene-Superconductor Photonic Integrated Circuits.
Samane Kalhor, Stephen J Kindness, Robert Wallis, Harvey E Beere, Majid Ghanaatshoar, Riccardo Degl'Innocenti, Michael J Kelly, Stephan Hofmann, Hannah J Joyce, David A Ritchie, Kaveh Delfanazari
Jan 10, 2022
Metamaterial photonic integrated circuits with arrays of hybrid graphene-superconductor coupled split-ring resonators (SRR) capable of modulating and slowing down terahertz (THz) light are introduced and proposed. The hybrid...
Feline Calicivirus Infection Disrupts Assembly of Cytoplasmic Stress Granules and Induces G3BP1 Cleavage.
Majid N Humoud, Nicole Doyle, Elizabeth Royall, Margaret M Willcocks, Frederic Sorgeloos, Frank van Kuppeveld, Lisa O Roberts, Ian G Goodfellow, Martijn A Langereis, Nicolas Locker
Nov 20, 2017
UNLABELLED: In response to stress such as virus infection, cells can stall translation by storing mRNAs away in cellular compartments called stress granules (SGs). This defense mechanism favors cell survival by limiting the use...
3C Viral Proteases Animals Caliciviridae Infections calicivirus Feline Carrier Proteins Cats Cysteine Endopeptidases Cytoplasmic Granules DNA Helicases Eukaryotic Initiation Factor-2 HeLa Cells Host-Pathogen Interactions Humans Mitogen-Activated Protein Kinases Phosphorylation Poly-ADP-Ribose Binding Proteins RNA Helicases RNA Recognition Motif Proteins Viral Proteins Virus Replication
The contribution of leading diseases and risk factors to excess losses of healthy life in Eastern Europe
A Model of Cloud Forensic Application With Assurance of Cloud Log
The key concepts of digital forensic investigation in cloud computing are examination and investigation. Cybercriminals target cloud-based web applications due to presence of vulnerabilities. Forensic investigation is a complex...
Published by: IGI Global Scientific Publishing
Depression amongst interns working in a tertiary care teaching Hospital in Maharashtra
Background: Internship is a crucial stage of medical school regarding student stress which can affect thepatient care negatively. Retrieving knowledge about presence of depression is therefore important in itself and iffound...
Published by: IJHS Medical Association
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