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Information Requirements Analysis for Holonic Manufacturing Systems in a Virtual Environment
The design and development of holonic manufacturing systems requires careful, and sometimes risky, decision making to ensure that they will successfully satisfy the demands of an ever-changing market. In this paper, the authors...
Information Requirements Analysis for Holonic Manufacturing Systems in a Virtual Environment
The design and development of holonic manufacturing systems requires careful, and sometimes risky, decision making to ensure that they will successfully satisfy the demands of an ever-changing market. In this paper, the authors...
Attention Res-UNet
During a dermoscopy examination, accurate and automatic skin lesion detection and segmentation can assist medical experts in resecting problematic areas and decrease the risk of deaths due to skin cancer. In order to develop...
Published by: IGI Global Scientific Publishing
An Ensemble Random Forest Algorithm for Privacy Preserving Distributed Medical Data Mining
As the voluminous amount of data is generated because of inexorably widespread proliferation of electronic data maintained using the Electronic Health Records (EHRs). Medical health facilities have great potential to discern the...
Published by: IGI Global Scientific Publishing
Analysis of Cloud Bursting on Openstack Infrastructure to AWS
Cloud computing is the development of distributed and parallel computing that seeks to provide a new model of business computing by automating services and efficiently storing proprietary data. Cloud bursting is one of the cloud...
OpenStack VM infrastructure private cloud public cloud cloud burst VM container Computer and Systems Architecture Computer Sciences Digital Communications and Networking
Published by: Harrisburg University of Science and Technology
Low defect and high electrical conductivity of graphene through plasma graphene healing treatment monitored with in situ optical emission spectroscopy.
Mohammad Salehi, Parnia Bastani, Loghman Jamilpanah, Abbas Madani, Seyed Majid Mohseni, Babak Shokri
Oct 13, 2021
Fundamental studies on graphene (Gr) and its real device applications have been affected by unavoidable defects and impurities which are usually present in synthesized Gr. Therefore, post treatment methods on Gr have been an...
The contribution of leading diseases and risk factors to excess losses of healthy life in Eastern Europe
Millimeter-Wave-to-Terahertz Superconducting Plasmonic Waveguides for Integrated Nanophotonics at Cryogenic Temperatures.
Samane Kalhor, Majid Ghanaatshoar, Hannah J Joyce, David A Ritchie, Kazuo Kadowaki, Kaveh Delfanazari
Sep 27, 2021
Plasmonics, as a rapidly growing research field, provides new pathways to guide and modulate highly confined light in the microwave-to-optical range of frequencies. We demonstrated a plasmonic slot waveguide, at the nanometer...
One-year changes in brain microstructure differentiate preclinical Huntington's disease stages.
Chris Patrick Pflanz, Marina Charquero-Ballester, DS Adnan Majid, Anderson M Winkler, Emmanuel Vallée, Adam R Aron, Mark Jenkinson, Gwenaëlle Douaud
Feb 13, 2020
OBJECTIVE: To determine whether brain imaging markers of tissue microstructure can detect the effect of disease progression across the preclinical stages of Huntington's disease. METHODS: Longitudinal microstructural changes in...
Millimeter-Wave-to-Terahertz Superconducting Plasmonic Waveguides for Integrated Nanophotonics at Cryogenic Temperatures
Samane Kalhor, Majid Ghanaatshoar, Hannah J. Joyce, David A. Ritchie, Kazuo Kadowaki, Kaveh Delfanazari
Aug 02, 2021
Plasmonics, as a rapidly growing research field, provides new pathways to guide and modulate highly confined light in the microwave-to-optical range of frequencies. We demonstrated a plasmonic slot waveguide, at the nanometer...
The rK39 Antigen from an Iranian Strain of Leishmania infantum
Bibi Razieh Hosseini Farash, Mehdi Mohebali, Bahram Kazemi, Homa Hajjaran, Abdolmajid Fata, Reza Raoofian, Behnaz Akhoundi, Majid Mojarrad, Pietro Mastroeni, Mohammad Kazem Sharifi-Yazdi, Mohammad Hossein Tanipour
Mar 31, 2020
BACKGROUND: Visceral leishmaniasis (VL) is the most severe form of leishmaniasis in Iran with high mortality rates in the case of inaccurate diagnosis and treatment. This study aimed to prepare and evaluate a new rk39...
Natural Biomaterials for Cardiac Tissue Engineering
Qasim A. Majid, Annabelle T. R. Fricker, David A. Gregory, Natalia Davidenko, Olivia Hernandez Cruz, Richard J. Jabbour, Thomas J. Owen, Pooja Basnett, Barbara Lukasiewicz, Molly Stevens, Serena Best, Ruth Cameron, Sanjay Sinha, Sian E. Harding, Ipsita Roy
Nov 09, 2020
Cardiovascular diseases (CVD) constitute a major fraction of the current major global diseases and lead to about 30% of the deaths, i.e., 17.9 million deaths per year. CVD include coronary artery disease (CAD), myocardial...
Active Terahertz Modulator and Slow Light Metamaterial Devices with Hybrid Graphene–Superconductor Photonic Integrated Circuits
Samane Kalhor, Stephen J. Kindness, Robert Wallis, Harvey E. Beere, Majid Ghanaatshoar, Riccardo Degl′Innocenti, Michael J. Kelly, Stephan Hofmann, Hannah J. Joyce, David A. Ritchie, Kaveh Delfanazari
Nov 12, 2021
Metamaterial photonic integrated circuits with arrays of hybrid graphene–superconductor coupled split-ring resonators (SRR) capable of modulating and slowing down terahertz (THz) light are introduced and proposed. The hybrid...
Modelling the Evolution of Pore Structure during the Disintegration of Pharmaceutical Tablets.
Mithushan Soundaranathan, Mohammed Al-Sharabi, Thomas Sweijen, Prince Bawuah, J Axel Zeitler, S Majid Hassanizadeh, Kendal Pitt, Blair F Johnston, Daniel Markl
Mar 28, 2023
Pharmaceutical tablet disintegration is a critical process for dissolving and enabling the absorption of the drug substance into the blood stream. The tablet disintegration process consists of multiple connected and...
Published by: Pharmaceutics
Natural Biomaterials for Cardiac Tissue Engineering
Qasim A Majid, Annabelle TR Fricker, David A Gregory, Natalia Davidenko, Olivia Hernandez Cruz, Richard J Jabbour, Thomas J Owen, Pooja Basnett, Barbara Lukasiewicz, Molly Stevens, Serena Best, Ruth Cameron, Sanjay Sinha, Sian E Harding, Ipsita Roy
Nov 23, 2020
Cardiovascular diseases (CVD) constitute a major fraction of the current major global diseases and lead to about 30% of the deaths, i.e., 17.9 million deaths per year. CVD include coronary artery disease (CAD), myocardial...
Feline Calicivirus Infection Disrupts Assembly of Cytoplasmic Stress Granules and Induces G3BP1 Cleavage.
Majid N Humoud, Nicole Doyle, Elizabeth Royall, Margaret M Willcocks, Frederic Sorgeloos, Frank van Kuppeveld, Lisa O Roberts, Ian G Goodfellow, Martijn A Langereis, Nicolas Locker
Nov 20, 2017
UNLABELLED: In response to stress such as virus infection, cells can stall translation by storing mRNAs away in cellular compartments called stress granules (SGs). This defense mechanism favors cell survival by limiting the use...
3C Viral Proteases Animals Caliciviridae Infections calicivirus Feline Carrier Proteins Cats Cysteine Endopeptidases Cytoplasmic Granules DNA Helicases Eukaryotic Initiation Factor-2 HeLa Cells Host-Pathogen Interactions Humans Mitogen-Activated Protein Kinases Phosphorylation Poly-ADP-Ribose Binding Proteins RNA Helicases RNA Recognition Motif Proteins Viral Proteins Virus Replication
Active Terahertz Modulator and Slow Light Metamaterial Devices with Hybrid Graphene-Superconductor Photonic Integrated Circuits.
Samane Kalhor, Stephen J Kindness, Robert Wallis, Harvey E Beere, Majid Ghanaatshoar, Riccardo Degl'Innocenti, Michael J Kelly, Stephan Hofmann, Hannah J Joyce, David A Ritchie, Kaveh Delfanazari
Jan 10, 2022
Metamaterial photonic integrated circuits with arrays of hybrid graphene-superconductor coupled split-ring resonators (SRR) capable of modulating and slowing down terahertz (THz) light are introduced and proposed. The hybrid...
The obesity transition
Lindsay M Jaacks, Stefanie Vandevijvere, An Pan, Craig J McGowan, Chelsea Wallace, Fumiaki Imamura, Dariush Mozaffarian, Boyd Swinburn, Majid Ezzati
Feb 07, 2019
The global prevalence of obesity has increased substantially over the past 40 years, from less than 1% in 1975, to 6-8% in 2016, among girls and boys, and from 3% to 11% among men and from 6% to 15% among women over the same...
Immunoglobulin replacement for secondary immunodeficiency after B-cell targeted therapies in autoimmune rheumatic disease
Sonali Wijetilleka, Chetan Mukhtyar, David Jayne, Aftab Ala, Philip Bright, Hector Chinoy, Lorraine Harper, Majid Kazmi, Sorena Kiani-Alikhan, Charles Li, Siraj Misbah, Louise Oni, Fiona Price-Kuehne, Alan Salama, Sarita Workman, David Wrench, Mohammed Yousuf Karim
Feb 24, 2020
BACKGROUND: Consensus guidelines are not available for the use of immunoglobulin replacement therapy (IGRT) in patients developing iatrogenic secondary antibody deficiency following B-cell targeted therapy (BCTT) in autoimmune...
Mitochondrial damage contributes to Pseudomonas aeruginosa activation of the inflammasome and is downregulated by autophagy.
Majid Sakhi Jabir, Lee Hopkins, Neil D Ritchie, Ihsan Ullah, Hannah K Bayes, Dong Li, Panagiotis Tourlomousis, Alison Lupton, Daniel Puleston, Anna Katharina Simon, Clare Bryant, Thomas J Evans
Jul 16, 2018
The nucleotide-binding domain, leucine-rich repeat containing family caspase recruitment domain containing 4 (NLRC4) inflammasome can be activated by pathogenic bacteria via products translocated through the microbial type III...
AIM2 absent in melanoma 2 ATG autophagy related ATPIF1 ATPase inhibitory factor 1 BID BH3 interacting domain death agonist BMDM bone marrow-derived macrophages BrdU 5-bromo-2-deoxyuridine CASP caspase DNA detection GFP green fluorescent protein IL1B interleukin 1 β LC3B microtubule-associated protein 1 light chain 3 β LDH lactate dehydrogenase LPS lipopolysaccharide MT-CO1 mitochondrially encoded cytochrome c oxidase I Mito-TEMPO (2-(2 2 6 6-tetramethylpiperidin-1-oxyl-4-ylamino)-2-oxoethyl)triphenylphosphonium chloride NAc N-acetylcysteine NAIP NLR family apoptosis inhibitor NGS normal goat serum NLR proteins NLR nucleotide-binding domain leucine-rich repeat containing NLRC4 NLR family CARD domain containing 4 NLRP3 NLR family pyrin domain containing 3 PBS phosphate-buffered saline PINK1 PTEN induced putative kinase 1 Rn18s 18S rRNA T3SS type III secretion system TNF Tumor Necrosis Factor TUBB5 tubulin β 5 class I Three-MA 3-methyladenine Vav vav 1 oncogene Infection mitophagy mtDNA mitochondrial DNA type III secretion system Animals Apoptosis Regulatory Proteins Autophagy Bone Marrow Cells Calcium-Binding Proteins DNA Mitochondrial DNA-Binding Proteins Down-Regulation Female HEK293 Cells Humans Inflammasomes MACROPHAGES Mice Inbred C57BL Mitochondria mitophagy Protein Binding Pseudomonas Infections Pseudomonas aeruginosa Reactive Oxygen Species
Recommendations for the management of secondary hypogammaglobulinaemia due to B cell targeted therapies in autoimmune rheumatic diseases.
Sonali Wijetilleka, David R Jayne, Chetan Mukhtyar, Aftab Ala, Philip D Bright, Hector Chinoy, Lorraine Harper, Majid A Kazmi, Sorena Kiani-Alikhan, Charles K Li, Siraj A Misbah, Louise Oni, Fiona E Price-Kuehne, Alan D Salama, Sarita Workman, David Wrench, Mohammed Yousuf Karim
Nov 27, 2019
OBJECTIVES: The association of B cell targeted therapies with development of hypogammaglobulinaemia and infection is increasingly recognized. Our aim was to develop consensus recommendations for immunoglobulin replacement...
Potential of Non-Coding RNA as Biomarkers for Progressive Supranuclear Palsy.
Fabio A Simoes, Greig Joilin, Oliver Peters, Luisa-Sophie Schneider, Josef Priller, Eike Jakob Spruth, Ina Vogt, Okka Kimmich, Annika Spottke, Daniel C Hoffmann, Björn Falkenburger, Moritz Brandt, Johannes Prudlo, Kathrin Brockmann, Franca Laura Fries, James B Rowe, Alistair Church, Gesine Respondek, Sarah F Newbury, P Nigel Leigh, Huw R Morris, Günter U Höglinger, Majid Hafezparast
Jan 10, 2023
Objective markers for the neurodegenerative disorder progressive supranuclear palsy (PSP) are needed to provide a timely diagnosis with greater certainty. Non-coding RNA (ncRNA), including microRNA, piwi-interacting RNA, and...
Potential of Non-Coding RNA as Biomarkers for Progressive Supranuclear Palsy.
Fabio A Simoes, Greig Joilin, Oliver Peters, Luisa-Sophie Schneider, Josef Priller, Eike Jakob Spruth, Ina Vogt, Okka Kimmich, Annika Spottke, Daniel C Hoffmann, Björn Falkenburger, Moritz Brandt, Johannes Prudlo, Kathrin Brockmann, Franca Laura Fries, James B Rowe, Alistair Church, Gesine Respondek, Sarah F Newbury, P Nigel Leigh, Huw R Morris, Günter U Höglinger, Majid Hafezparast
Dec 08, 2022
Mutations in ELAC2 associated with hypertrophic cardiomyopathy impair mitochondrial tRNA 3'-end processing.
Makenzie Saoura, Christopher A Powell, Robert Kopajtich, Ahmad Alahmad, Haya H Al-Balool, Buthaina Albash, Majid Alfadhel, Charlotte L Alston, Enrico Bertini, Penelope E Bonnen, Drago Bratkovic, Rosalba Carrozzo, Maria A Donati, Michela Di Nottia, Daniele Ghezzi, Amy Goldstein, Eric Haan, Rita Horvath, Joanne Hughes, Federica Invernizzi, Eleonora Lamantea, Benjamin Lucas, Kyla-Gaye Pinnock, Maria Pujantell, Shamima Rahman, Pedro Rebelo-Guiomar, Saikat Santra, Daniela Verrigni, Robert McFarland, Holger Prokisch, Robert W Taylor, Louis Levinger, Michal Minczuk
May 31, 2019
Mitochondria RNA RNase Z Cardiomyopathy mitochondrial disease Alleles Amino Acid Substitution Biomarkers Cardiomyopathy Hypertrophic Cohort Studies Enzyme Activation Female Gene Expression Genes Mitochondrial Genetic Association Studies Genetic Predisposition to Disease Genotype Humans Infant Kinetics Male Mutation Neoplasm Proteins Phenotype Protein Conformation Protein Interaction Domains and Motifs RNA processing Post-Transcriptional RNA Transfer Structure-Activity Relationship Substrate Specificity
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