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A Head-Mounted Camera System Integrates Detailed Behavioral Monitoring with Multichannel Electrophysiology in Freely Moving Mice.
Breakthroughs in understanding the neural basis of natural behavior require neural recording and intervention to be paired with high-fidelity multimodal behavioral monitoring. An extensive genetic toolkit for neural circuit...
Gastrocnemius release is an effective management option for Achilles tendinopathy
PURPOSE: This systematic review aims to summarise the outcomes of gastrocnemius release in the management of Achilles Tendinopathy. METHODS: A systematic review was performed according to PRISMA guidelines. A computer-based...
Gastrocnemius Release in the Management of Chronic Plantar Fasciitis
BACKGROUND: This systematic review aims to summarize the outcomes of gastrocnemius recession in the treatment of plantar fasciitis. METHODS: A systematic review was performed according to PRISMA guidelines using the PubMed...
Management of chronic Achilles ruptures
PURPOSE: This scoping review aims to systematically map and summarise the available evidence on the management of chronic Achilles ruptures, whilst identifying prognostic factors and areas of future research. METHODS: A scoping...
Increased brain age in adults with Prader-Willi syndrome.
Adriana M Azor, James H Cole, Anthony J Holland, Maureen Dumba, Maneesh C Patel, Angelique Sadlon, Anthony P Goldstone, Katherine E Manning
Feb 15, 2019
Prader-Willi syndrome (PWS) is the most common genetic obesity syndrome, with associated learning difficulties, neuroendocrine deficits, and behavioural and psychiatric problems. As the life expectancy of individuals with PWS...
Genome-wide association analysis identifies variants associated with nonalcoholic fatty liver disease that have distinct effects on metabolic traits.
Elizabeth K Speliotes, Laura M Yerges-Armstrong, Jun Wu, Ruben Hernaez, Lauren J Kim, Cameron D Palmer, Vilmundur Gudnason, Gudny Eiriksdottir, Melissa E Garcia, Lenore J Launer, Michael A Nalls, Jeanne M Clark, Braxton D Mitchell, Alan R Shuldiner, Johannah L Butler, Marta Tomas, Udo Hoffmann, Shih-Jen Hwang, Joseph M Massaro, Christopher J O'Donnell, Dushyant V Sahani, Veikko Salomaa, Eric E Schadt, Stephen M Schwartz, David S Siscovick, NASH CRN, GIANT Consortium, MAGIC Investigators, Benjamin F Voight, J Jeffrey Carr, Mary F Feitosa, Tamara B Harris, Caroline S Fox, Albert V Smith, WH Linda Kao, Joel N Hirschhorn, Ingrid B Borecki, GOLD Consortium
Jan 23, 2018
Nonalcoholic fatty liver disease (NAFLD) clusters in families, but the only known common genetic variants influencing risk are near PNPLA3. We sought to identify additional genetic variants influencing NAFLD using genome-wide...
Adaptor Proteins Signal Transducing Adult Aged Aged 80 and over Blood Glucose Case-Control Studies Chondroitin Sulfate Proteoglycans Cohort Studies Fatty Liver Genome-Wide Association Study Humans Insulin Lectins C-Type LIPASE Male Membrane Proteins Middle Aged Mutation Missense Nerve Tissue Proteins Neurocan non-alcoholic fatty liver disease Polymorphism Single Nucleotide Quantitative Trait Loci Tomography X-Ray Computed