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Retinal regions shape human and murine Müller cell proteome profile and functionality.
Lew Kaplan, Corinne Drexler, Anna M Pfaller, Santra Brenna, Kirsten A Wunderlich, Andrea Dimitracopoulos, Juliane Merl-Pham, Maria-Theresa Perez, Ursula Schlötzer-Schrehardt, Volker Enzmann, Marijana Samardzija, Berta Puig, Peter Fuchs, Kristian Franze, Stefanie M Hauck, Antje Grosche
Nov 05, 2022
The human macula is a highly specialized retinal region with pit-like morphology and rich in cones. How Müller cells, the principal glial cell type in the retina, are adapted to this environment is still poorly understood. We...
Is Mycobacterium tuberculosis infection life long?
People with immunoreactivity to tuberculosis are thought to have lifelong asymptomatic infection and remain at risk for active tuberculosis. Marcel A Behr and colleagues argue that most of these people are no longer infected
Revisiting the timetable of tuberculosis.
Tuberculosis has a much shorter incubation period than is widely thought, say Marcel A Behr and colleagues, and this has implications for prioritising research and public health strategies
Language as a force for good in the work of Herta Müller
P Shopin
Oct 02, 2017
Herta Müller creates sophisticated metaphors to convey her vision of language and its relationship to suffering and subjugation. With reference to both her fiction and non‐fiction, this essay explores how she uses the idea of...
The Trope of Silence in the Work of Herta Müller
P Shopin
Aug 09, 2017
With reference to Herta Müller’s fiction and non-fiction, my essay explores how the trope of silence is engaged to make sense of more abstract concepts. Drawing on conceptual metaphor theory, I argue that Müller uses silence as...
Factors determining human-to-human transmissibility of zoonotic pathogens via contact.
Mathilde Richard, Sascha Knauf, Philip Lawrence, Alison E Mather, Vincent J Munster, Marcel A Müller, Derek Smith, Thijs Kuiken
Jun 12, 2020
The pandemic potential of zoonotic pathogens lies in their ability to become efficiently transmissible amongst humans. Here, we focus on contact-transmitted pathogens and discuss the factors, at the pathogen, host and...
ROBO3s
Marcel Werner, Anna Dyas, Iwan Parfentev, Geske E Schmidt, Iga K Mieczkowska, Lukas C Müller-Kirschbaum, Claudia Müller, Stefan Kalkhof, Oliver Reinhardt, Henning Urlaub, Frauke Alves, Julia Gallwas, Evangelos Prokakis, Florian Wegwitz
Oct 04, 2022
Basal-like breast cancer (BLBC) is a highly aggressive breast cancer subtype frequently associated with poor prognosis. Due to the scarcity of targeted treatment options, conventional cytotoxic chemotherapies frequently remain...
ROBO3s
Marcel Werner, Anna Dyas, Iwan Parfentev, Geske E Schmidt, Iga K Mieczkowska, Lukas C Müller-Kirschbaum, Claudia Müller, Stefan Kalkhof, Oliver Reinhardt, Henning Urlaub, Frauke Alves, Julia Gallwas, Evangelos Prokakis, Florian Wegwitz
Sep 03, 2022
Basal-like breast cancer (BLBC) is a highly aggressive breast cancer subtype frequently associated with poor prognosis. Due to the scarcity of targeted treatment options, conventional cytotoxic chemotherapies frequently remain...
Gabriel(le) et Marcel(le): La Fluidité du Genre dans Gabriel (1839) de George Sand et Madame Adonis (1888) de Rachilde
Elisa Rodriguez
Jan 01, 0001
George Sand and Rachilde, two important French female writers of the 19th c, discuss androgynous characters and borderline homosexual relationships in their works. They are part of a larger literary trend obsessed with liminal...
Rachilde George Sand 19th century Francophone literature Gender sexuality Arts and Humanities Feminist, Gender, and Sexuality Studies French and Francophone Language and Literature
Published by: Ursinus College
Quality control in oocytes by p63 is based on a spring-loaded activation mechanism on the molecular and cellular level.
Daniel Coutandin, Christian Osterburg, Ratnesh Kumar Srivastav, Manuela Sumyk, Sebastian Kehrloesser, Jakob Gebel, Marcel Tuppi, Jens Hannewald, Birgit Schäfer, Eidarus Salah, Sebastian Mathea, Uta Müller-Kuller, James Doutch, Manuel Grez, Stefan Knapp, Volker Dötsch
Nov 13, 2018
Mammalian oocytes are arrested in the dictyate stage of meiotic prophase I for long periods of time, during which the high concentration of the p53 family member TAp63α sensitizes them to DNA damage-induced apoptosis. TAp63α is...
DNA Damage E. coli biophysics Cell Biology kinetically trapped state MOUSE Oocytes p63 Quality Control spring-loaded activation structural biology Animals Apoptosis DNA Damage Female Mice Oocytes Phosphoproteins Phosphorylation Protein Multimerization Protein Processing Post-Translational Quality Control Trans-Activators
Impact of dexamethasone on SARS-CoV-2 concentration kinetics and antibody response in hospitalized COVID-19 patients
Barbara Mühlemann, Charlotte Thibeault, David Hillus, Elisa T Helbig, Lena J Lippert, Pinkus Tober-Lau, Tatjana Schwarz, Marcel A Müller, Pa-COVID-19 collaborative study group, Martin Witzenrath, Norbert Suttorp, Leif E Sander, Christian Drosten, Terry C Jones, Victor M Corman, Florian Kurth
Jul 28, 2021
OBJECTIVES: Dexamethasone has become the standard of care for severe coronavirus disease 2019 (COVID-19), but its virological impact is poorly understood. The objectives of this work were to characterize the kinetics of severe...
Antibody COVID-19 Nucleic Acid Testing Coronavirus disease 2019 (COVID-19) Dexamethasone Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) Viral concentration Anti-Inflammatory Agents Antibodies Viral covid-19 Dexamethasone Hospitalization Humans Immunoglobulin A Immunoglobulin G Kinetics Prospective Studies RNA Viral Respiratory System SARS-CoV-2 Seroconversion Viral Load COVID-19 Drug Treatment
If You're Happy, I'm Happy
An increasing body of research has addressed what a tourism experience is and how it should best be measured and managed. One conclusion has been to recommend observational methods such as facial expression analysis. The chapter...
Business and Management Hospitality Travel and Tourism Management Hospitality Travel & Tourism Management Social Sciences and Humanities Media and Communications
Published by: IGI Global Scientific Publishing
IL-33 deficiency causes persistent inflammation and severe neurodegeneration in retinal detachment.
Josy Augustine, Sofia Pavlou, Imran Ali, Kevin Harkin, Ema Ozaki, Matthew Campbell, Alan W Stitt, Heping Xu, Mei Chen
Jan 20, 2020
BACKGROUND: Interleukin-33 (IL-33) belongs to the IL-1 cytokine family and resides in the nuclei of various cell types. In the neural retina, IL-33 is predominately expressed in Müller cells although its role in health and...
Mammalian deltavirus without hepadnavirus coinfection in the neotropical rodent Proechimys semispinosus.
Sofia Paraskevopoulou, Fabian Pirzer, Nora Goldmann, Julian Schmid, Victor Max Corman, Lina Theresa Gottula, Simon Schroeder, Andrea Rasche, Doreen Muth, Jan Felix Drexler, Alexander Christoph Heni, Georg Joachim Eibner, Rachel A Page, Terry C Jones, Marcel A Müller, Simone Sommer, Dieter Glebe, Christian Drosten
Jul 14, 2020
Hepatitis delta virus (HDV) is a human hepatitis-causing RNA virus, unrelated to any other taxonomic group of RNA viruses. Its occurrence as a satellite virus of hepatitis B virus (HBV) is a singular case in animal virology for...
A new look at duality for the symbiotic branching model
The symbiotic branching model is a spatial population model describing the dynamics of two interacting types that can only branch if both types are present. A classical result for the underlying stochastic partial...
A new look at duality for the symbiotic branching model
The symbiotic branching model is a spatial population model describing the dynamics of two interacting types that can only branch if both types are present. A classical result for the underlying stochastic partial...
The Grizzly, February 16, 1979
Jack Hauler, Thomas A. Reilly, Kevin Ludwig, Gary Aaronson, William T. Parsons, Mark Woodland, Kathy McSharry, Jay Repko, James Wilson, Michael Newman, Wesley Emmons, Frank Shannon, Rick Morris, David Garner
Jan 01, 0001
Fraternity Pledging Under College Scrutiny College Bowl: A Positive Note Middle States, Course Evaluation Approved By Faculty Men's Campus Council Explores Centralized Mail Pledging Begins Basic Assumption Letters to the...
Ursinus College Collegeville Pennsylvania newspaper fraternities pledging Intercollegiate College Bowl Theft Men's Campus Council Mail Dorm hours sex William J. Phillips prize French Club Mignon Bozorth skiing Audio equipment Joyce Henry Tim Todd baseball Basketball Swimming cultural history Higher Education Liberal Studies Social History United States History
Published by: Ursinus College
Anti-decubitus bed mattress may interfere with cerebrovascular pressure reactivity measures due to induced ICP and ABP cyclic peaks.
Tas Jeanette, Borg Melisa, Smielewski Peter, Czosnyka Marek, Beqiri Erta, Ercole Ari, Aries Marcel
Jan 29, 2020
Severe traumatic brain injury (TBI) patients are monitored with continuous arterial blood pressure (ABP) and intracranial pressure (ICP). The pressure reactivity index (PRx) is a frequently used correlation coefficient between...
A phase transition for preferential attachment models with additive fitness
Preferential attachment models form a popular class of growing networks, where Preferential attachment models form a popular class of growing networks, where incoming vertices are preferably connected to vertices with high...
Fluctuations in a general preferential attachment model via Stein's method
We consider a class of dynamic random graphs known as preferential attachment models, where the probability that a new vertex connects to an older vertex is proportional to a sublinear function of the indegree of the older...
Xavier Tilliette on Revelation as the Measure of Reason
Tyler Tritten
Apr 05, 2022
Xavier Tilliette, born in Sommes, France in 1921, passed away on 10 December 2018 at the age of 97. Although he first gained notoriety for his many studies of Schelling, he has also published numerous books and articles on...
Published by: Memorial University Libraries
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