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Results: 61
How to Think Actuality? Schelling, Aristotle and the Problem of the Pure Daß
Marcela Garcia
Aug 29, 2018
In this paper, I address a problem of Schelling’s late philosophy: the relation between negative and positive philosophy, and the role of the “pure Daß” in the transition from one to the other. While the so-called transition is...
Published by: Memorial University Libraries
A horizon scan of global biological conservation issues for 2022
William J Sutherland, Philip W Atkinson, Stuart HM Butchart, Marcela Capaja, Lynn V Dicks, Erica Fleishman, Kevin J Gaston, Rosemary S Hails, Alice C Hughes, Becky Le Anstey, Xavier le Roux, Fiona A Lickorish, Luke Maggs, Noor Noor, Thomasina EE Oldfield, James E Palardy, Lloyd S Peck, Nathalie Pettorelli, Jules Pretty, Mark D Spalding, Femke H Tonneijck, Gemma Truelove, James EM Watson, Jonathan Wentworth, Jeremy D Wilson, Ann Thornton
Nov 25, 2021
How to Think Actuality? Schelling, Aristotle and the Problem of the Pure Daß
Marcela Garcia
Aug 29, 2018
In this paper, I address a problem of Schelling’s late philosophy: the relation between negative and positive philosophy, and the role of the “pure Daß” in the transition from one to the other. While the so-called transition is...
Published by: Memorial University Libraries
Experimental assessment of mating opportunities in three shorebird species
Mating opportunities may differ between closely related species, although the evidence for such variation is scant. Here we compare remating opportunities and courtship behaviour between three shorebird species: the Kentish...
A Literature Review of E-Government Research in Mexico Utilizing the PRISMA Methodology
This research aims to understand the state of the art in Mexico's e-government research field, research trends, empirical research, e-government access, adoption, and availability of online services. Through a systematic...
Published by: IGI Global Scientific Publishing
Simulation-based benchmarking of isoform quantification in single-cell RNA-seq.
Single-cell RNA-seq has the potential to facilitate isoform quantification as the confounding factor of a mixed population of cells is eliminated. However, best practice for using existing quantification methods has not been...
Experimental assessment of mating opportunities in three shorebird species
Mating opportunities may differ between closely related species, although the evidence for such variation is scant. Here we compare remating opportunities and courtship behaviour between three shorebird species: the Kentish...
Soluble silica stimulates osteogenic differentiation and gap junction communication in human dental follicle cells
Pamela Uribe, Anders Johansson, Ravin Jugdaohsingh, Jonathan J. Powell, Catarina Magnusson, Marcela Davila, Anna Westerlund, Maria Ransjö
Jun 18, 2020
Abstract: Several studies have indicated that dietary silicon (Si) is beneficial for bone homeostasis and skeletal health. Furthermore, Si-containing bioactive glass biomaterials have positive effects on bone regeneration when...
Soluble silica stimulates osteogenic differentiation and gap junction communication in human dental follicle cells.
Pamela Uribe, Anders Johansson, Ravin Jugdaohsingh, Jonathan J Powell, Catarina Magnusson, Marcela Davila, Anna Westerlund, Maria Ransjö
Jun 18, 2021
Several studies have indicated that dietary silicon (Si) is beneficial for bone homeostasis and skeletal health. Furthermore, Si-containing bioactive glass biomaterials have positive effects on bone regeneration when used for...
Clinical utility gene card for
Neringa Jurkute, Anna Majander, Richard Bowman, Marcela Votruba, Stephen Abbs, James Acheson, Guy Lenaers, Patrizia Amati-Bonneau, Mariya Moosajee, Gavin Arno, Patrick Yu-Wai-Man
May 13, 2019
Active Human and Porcine Serum Induce Competence for Genetic Transformation in the Emerging Zoonotic Pathogen Streptococcus suis.
Maria Laura Ferrando, Alex Gussak, Saskia Mentink, Marcela Fernandez Gutierrez, Peter van Baarlen, Jerry Mark Wells
Apr 16, 2021
The acquisition of novel genetic traits through natural competence is a strategy used by bacteria in microbe-rich environments where microbial competition, antibiotics, and host immune defenses threaten their survival. Here, we...
Deciphering the role of miR-71 in Echinococcus multilocularis early development in vitro.
Matías Gastón Pérez, Markus Spiliotis, Natalia Rego, Natalia Macchiaroli, Laura Kamenetzky, Nancy Holroyd, Marcela Alejandra Cucher, Klaus Brehm, Mara Cecilia Rosenzvit
Jan 13, 2020
Echinococcosis represents a major public health problem worldwide and is considered a neglected disease by the World Health Organization. The etiological agents are Echinococcus tapeworms, which display elaborate developmental...
Identification, Characterization, and Heritability of Murine Metastable Epialleles
Anastasiya Kazachenka, Tessa M Bertozzi, Marcela K Sjoberg-Herrera, Nic Walker, Joseph Gardner, Richard Gunning, Elena Pahita, Sarah Adams, David Adams, Anne C Ferguson-Smith
Nov 21, 2018
Generally repressed by epigenetic mechanisms, retrotransposons represent around 40% of the murine genome. At the Agouti viable yellow (Avy) locus, an endogenous retrovirus (ERV) of the intracisternal A particle (IAP) class...
Modulation of the potassium channel KcsA by anionic phospholipids
José A Poveda, A Marcela Giudici, M Lourdes Renart, Oscar Millet, Andrés Morales, José M González-Ros, Victoria Oakes, Simone Furini, Carmen Domene
Oct 01, 2019
The role of arginines R64 and R89 at non-annular lipid binding sites of KcsA, on the modulation of channel activity by anionic lipids has been investigated. In wild-type (WT) KcsA reconstituted into asolectin lipid membranes...
Ion channel inactivation Ion channel kinetics Membrane lipid-protein interactions molecular dynamics simulations Patch-clamp recordings /dk/atira/pure/subjectarea/asjc/1300/1304 name=Biophysics /dk/atira/pure/subjectarea/asjc/1300/1303 name=Biochemistry /dk/atira/pure/subjectarea/asjc/1300/1307 name=Cell Biology
The free energy landscape of the oncogene protein E7 of human papillomavirus type 16 reveals a complex interplay between ordered and disordered regions.
Predrag Kukic, Giuseppe Mattia Lo Piccolo, Marcela O Nogueira, Dmitri I Svergun, Michele Vendruscolo, Isabella C Felli, Roberta Pierattelli
Mar 29, 2019
Myopia disease mouse models
Katarzyna I Szczerkowska, Silvia Petrezselyova, Jiri Lindovsky, Marcela Palkova, Jan Dvorak, Peter Makovicky, Mingyan Fang, Chongyi Jiang, Lingyan Chen, Mingming Shi, Xiao Liu, Jianguo Zhang, Agnieszka Kubik-Zahorodna, Bjoern Schuster, Inken M Beck, Vendula Novosadova, Jan Prochazka, Radislav Sedlacek
Feb 24, 2020
Zinc finger 644 (Zfp644 in mouse, ZNF644 in human) gene is a transcription factor whose mutation S672G is considered a potential genetic factor of inherited high myopia. ZNF644 interacts with G9a/GLP complex, which functions as...
The genome sequence of the Norway rat, Rattus norvegicus Berkenhout 1769.
Kerstin Howe, Melinda Dwinell, Mary Shimoyama, Craig Corton, Emma Betteridge, Alexander Dove, Michael A Quail, Michelle Smith, Laura Saba, Robert W Williams, Hao Chen, Anne E Kwitek, Shane A McCarthy, Marcela Uliano-Silva, William Chow, Alan Tracey, James Torrance, Ying Sims, Richard Challis, Jonathan Threlfall, Mark Blaxter
Oct 22, 2021
We present a genome assembly from an individual male Rattus norvegicus (the Norway rat; Chordata; Mammalia; Rodentia; Muridae). The genome sequence is 2.44 gigabases in span. The majority of the assembly is scaffolded into 20...
Modulation of the potassium channel KcsA by anionic phospholipids
José A Poveda, A Marcela Giudici, M Lourdes Renart, Oscar Millet, Andrés Morales, José M González-Ros, Victoria Oakes, Simone Furini, Carmen Domene
Oct 01, 2019
The role of arginines R64 and R89 at non-annular lipid binding sites of KcsA, on the modulation of channel activity by anionic lipids has been investigated. In wild-type (WT) KcsA reconstituted into asolectin lipid membranes...
Ion channel inactivation Ion channel kinetics Membrane lipid-protein interactions molecular dynamics simulations Patch-clamp recordings /dk/atira/pure/subjectarea/asjc/1300/1304 name=Biophysics /dk/atira/pure/subjectarea/asjc/1300/1303 name=Biochemistry /dk/atira/pure/subjectarea/asjc/1300/1307 name=Cell Biology
Prediction of Early TBI Mortality Using a Machine Learning Approach in a LMIC Population
Robson Luis Amorim, Louise Makarem Oliveira, Luis Marcelo Malbouisson, Marcia Mitie Nagumo, Marcela Simoes, Leandro Miranda, Edson Bor-Seng-Shu, Andre Beer-Furlan, Almir Ferreira De Andrade, Andres M. Rubiano, Manoel Jacobsen Teixeira, Angelos G. Kolias, Wellingson Silva Paiva
Feb 07, 2020
Background: In a time when the incidence of severe traumatic brain injury (TBI) is increasing in low- to middle-income countries (LMICs), it is important to understand the behavior of predictive variables in an LMIC's...
Genomics of the Argentinian cholera epidemic elucidate the contrasting dynamics of epidemic and endemic Vibrio cholerae.
Matthew J Dorman, Daryl Domman, Tomás Poklepovich, Charlotte Tolley, Gisella Zolezzi, Leanne Kane, María Rosa Viñas, Marcela Panagópulo, Miriam Moroni, Norma Binsztein, María Inés Caffer, Simon Clare, Gordon Dougan, George PC Salmond, Julian Parkhill, Josefina Campos, Nicholas R Thomson
Nov 20, 2020
In order to control and eradicate epidemic cholera, we need to understand how epidemics begin, how they spread, and how they decline and eventually end. This requires extensive sampling of epidemic disease over time, alongside...
SSBP1 mutations in dominant optic atrophy with variable retinal degeneration.
Neringa Jurkute, Costin Leu, Hans-Martin Pogoda, Gavin Arno, Anthony G Robson, Gudrun Nürnberg, Janine Altmüller, Holger Thiele, Susanne Motameny, Mohammad Reza Toliat, Kate Powell, Wolfgang Höhne, Michel Michaelides, Andrew R Webster, Anthony T Moore, Matthias Hammerschmidt, Peter Nürnberg, Patrick Yu-Wai-Man, Marcela Votruba
Jul 26, 2019
OBJECTIVE: Autosomal dominant optic atrophy (ADOA) starts in early childhood with loss of visual acuity and color vision deficits. OPA1 mutations are responsible for the majority of cases, but in a portion of patients with a...
Levofloxacin induces differential effects in the transcriptome between the gut, peripheral and axial joints in the Spondyloarthritis DBA/1 mice
Susana Aideé González-Chávez, Joan S Salas-Leiva, Dayana E Salas-Leiva, Salma Marcela López-Loeza, Jasanai Sausameda-García, Erasmo Orrantia-Borunda, Rubén Burgos-Vargas, Maria Fernanda Alvarado-Jáquez, Mayra Torres-Quintana, Rubén Cuevas-Martínez, Eduardo Chaparro-Barrera, Carlos Marín-Terrazas, Gerardo Pável Espino-Solís, José Pablo Romero-López, Brian de Jesús Bernal-Alferes, César Pacheco-Tena
Feb 02, 2023
In Vivo Characterization of Linc-p21 Reveals Functional cis-Regulatory DNA Elements.
Abigail F Groff, Diana B Sanchez-Gomez, Marcela ML Soruco, Chiara Gerhardinger, A Rasim Barutcu, Eric Li, Lara Elcavage, Olivia Plana, Lluvia V Sanchez, James C Lee, Martin Sauvageau, John L Rinn
Mar 08, 2019
The Linc-p21 locus, encoding a long non-coding RNA, plays an important role in p53 signaling, cell-cycle regulation, and tumor suppression. However, despite extensive study, confusion exists regarding its mechanism of action: is...
Animals Base Sequence Cell Line Cyclin-Dependent Kinase Inhibitor p21 Enhancer Elements Genetic Gene Expression Regulation Genetic Loci High-Throughput Nucleotide Sequencing High-Throughput Screening Assays Mice Mice Knockout Myoblasts Promoter Regions Genetic RNA Long Noncoding Sequence Deletion Signal Transduction Tumor Suppressor Protein p53
Prediction of Early TBI Mortality Using a Machine Learning Approach in a LMIC Population.
Robson Luis Amorim, Louise Makarem Oliveira, Luis Marcelo Malbouisson, Marcia Mitie Nagumo, Marcela Simoes, Leandro Miranda, Edson Bor-Seng-Shu, Andre Beer-Furlan, Almir Ferreira De Andrade, Andres M Rubiano, Manoel Jacobsen Teixeira, Angelos G Kolias, Wellingson Silva Paiva
Mar 12, 2020
Background: In a time when the incidence of severe traumatic brain injury (TBI) is increasing in low- to middle-income countries (LMICs), it is important to understand the behavior of predictive variables in an LMIC's...
Published by: Frontiers in neurology
The genome sequence of the malaria mosquito, Anopheles funestus, Giles, 1900.
Diego Ayala, Ousman Akone-Ella, Pierre Kengne, Harriet Johnson, Haynes Heaton, Joanna Collins, Ksenia Krasheninnikova, Sarah Pelan, Damon-Lee Pointon, Ying Sims, James Torrance, Alan Tracey, Marcela Uliano-Silva, Katharina von Wyschetzki, Jonathan Wood, DNA Pipelines collective, Shane McCarthy, Daniel Neafsey, Alex Makunin, Mara Lawniczak
Apr 05, 2023
We present a genome assembly from an individual female Anopheles funestus (the malaria mosquito; Arthropoda; Insecta; Diptera; Culicidae). The genome sequence is 251 megabases in span. The majority of the assembly is scaffolded...
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