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Results: 63
Clinical applicability of the Polygenic Risk Score for breast cancer risk prediction in familial cases.
Inge MM Lakeman, Mar DM Rodríguez-Girondo, Andrew Lee, Nandi Celosse, Merel E Braspenning, Klaartje van Engelen, Irma van de Beek, Annemiek H van der Hout, Encarna B Gómez García, Arjen R Mensenkamp, Margreet Gem Ausems, Maartje J Hooning, Muriel A Adank, Antoinette Hollestelle, Marjanka K Schmidt, Christi J van Asperen, Peter Devilee
Oct 26, 2022
Clinical applicability of the Polygenic Risk Score for breast cancer risk prediction in familial cases.
Inge MM Lakeman, Mar DM Rodríguez-Girondo, Andrew Lee, Nandi Celosse, Merel E Braspenning, Klaartje van Engelen, Irma van de Beek, Annemiek H van der Hout, Encarna B Gómez García, Arjen R Mensenkamp, Margreet Gem Ausems, Maartje J Hooning, Muriel A Adank, Antoinette Hollestelle, Marjanka K Schmidt, Christi J van Asperen, Peter Devilee
Sep 27, 2022
The application of a monolithic triphenylphosphine reagent for conducting Ramirez gem-dibromoolefination reactions in flow.
The application of a monolithic form of triphenylphosphine to the Ramirez gem-dibromoolefination reaction using flow chemistry techniques is reported. A variety of gem-dibromides were synthesised in high purity and excellent...
Research on the Mediating Effect of Corporate Governance Behavior Between GEM and Governance Performance of Listed Companies on the Growth Enterprise
At the end of 2019, the sudden attack of the COVID-19 brought huge challenges to the management, operation and development of listed companies. In view of the suddenness of the epidemic, the internal governance of listed...
Published by: IGI Global Scientific Publishing
Complete loss of ATM function augments replication catastrophe induced by ATR inhibition and gemcitabine in pancreatic cancer models
Charles R. Dunlop, Yann Wallez, Timothy Isaac Johnson, Sandra Bernaldo de Quirós Fernández, Stephen T. Durant, Elaine B. Cadogan, Alan Lau, Frances M. Richards, Duncan I. Jodrell
Oct 27, 2020
Abstract: Background: Personalised medicine strategies may improve outcomes in pancreatic ductal adenocarcinoma (PDAC), but validation of predictive biomarkers is required. Having developed a clinical trial to assess the ATR...
Complete loss of ATM function augments replication catastrophe induced by ATR inhibition and gemcitabine in pancreatic cancer models
Charles R. Dunlop, Yann Wallez, Timothy Isaac Johnson, Sandra Bernaldo de Quirós Fernández, Stephen T. Durant, Elaine B. Cadogan, Alan Lau, Frances M. Richards, Duncan I. Jodrell
Feb 09, 2021
Abstract: Background: Personalised medicine strategies may improve outcomes in pancreatic ductal adenocarcinoma (PDAC), but validation of predictive biomarkers is required. Having developed a clinical trial to assess the ATR...
Complete loss of ATM function augments replication catastrophe induced by ATR inhibition and gemcitabine in pancreatic cancer models
Charles R. Dunlop, Yann Wallez, Timothy Isaac Johnson, Sandra Bernaldo de Quirós Fernández, Stephen T. Durant, Elaine B. Cadogan, Alan Lau, Frances M. Richards, Duncan I. Jodrell
Aug 03, 2021
Abstract: Background: Personalised medicine strategies may improve outcomes in pancreatic ductal adenocarcinoma (PDAC), but validation of predictive biomarkers is required. Having developed a clinical trial to assess the ATR...
Human inference beyond syllogisms
Research in psychology about reasoning has often been restricted to relatively inexpressive statements involving quantifiers (e.g. syllogisms). This is limited to situations that typically do not arise in practical settings...
Hereditary diffuse gastric cancer
Rachel S van der Post, Ingrid P Vogelaar, Fátima Carneiro, Parry Guilford, David Huntsman, Nicoline Hoogerbrugge, Carlos Caldas, Karen E Chelcun Schreiber, Richard H Hardwick, Margreet Gem Ausems, Linda Bardram, Patrick R Benusiglio, Tanya M Bisseling, Vanessa Blair, Eveline Bleiker, Alex Boussioutas, Annemieke Cats, Daniel Coit, Lynn DeGregorio, Joana Figueiredo, James M Ford, Esther Heijkoop, Rosella Hermens, Bostjan Humar, Pardeep Kaurah, Gisella Keller, Jennifer Lai, Marjolijn JL Ligtenberg, Maria O'Donovan, Carla Oliveira, Hugo Pinheiro, Krish Ragunath, Esther Rasenberg, Susan Richardson, Franco Roviello, Hans Schackert, Raquel Seruca, Amy Taylor, Anouk Ter Huurne, Marc Tischkowitz, Sheena Tjon A Joe, Benjamin van Dijck, Nicole CT van Grieken, Richard van Hillegersberg, Johanna W van Sandick, Rianne Vehof, J Han van Krieken, Rebecca C Fitzgerald
Feb 13, 2020
Germline CDH1 mutations confer a high lifetime risk of developing diffuse gastric (DGC) and lobular breast cancer (LBC). A multidisciplinary workshop was organised to discuss genetic testing, surgery, surveillance strategies...
Cancer: breast Cancer: gastric Clinical genetics Diagnostics Stomach and duodenum Antigens CD Breast Neoplasms Cadherins Colorectal Neoplasms DNA Mutational Analysis Early Detection of Cancer Female Genetic Counseling Genetic Testing Germ-Line Mutation Heterozygote Humans Population Surveillance Practice Guidelines as Topic Pregnancy Stomach Neoplasms
Anti-tumour efficacy of capecitabine in a genetically engineered mouse model of pancreatic cancer.
Aurélie Courtin, Frances M Richards, Tashinga E Bapiro, Jo L Bramhall, Albrecht Neesse, Natalie Cook, Ben-Fillippo Krippendorff, David A Tuveson, Duncan I Jodrell
Feb 12, 2020
Capecitabine (CAP) is a 5-FU pro-drug approved for the treatment of several cancers and it is used in combination with gemcitabine (GEM) in the treatment of patients with pancreatic adenocarcinoma (PDAC). However, limited...
Animals Antineoplastic Combined Chemotherapy Protocols Capecitabine Carcinoma Pancreatic Ductal Cell Line Tumor Cytidine Deaminase Deoxycytidine Disease Models Animal Drug Screening Assays Antitumor Fluorouracil Mice Mice Transgenic Neoplasm Transplantation Pancreatic Neoplasms prodrugs Tissue Distribution Gemcitabine
Evaluating Free Rides and Observational Advantages in Set Visualizations
Abstract: Free rides and observational advantages occur in visualizations when they reveal facts that must be inferred from an alternative representation. Understanding whether these concepts correspond to cognitive advantages...
Published by: Springer Netherlands
Visualizing Sets with Linear Diagrams
This paper presents the first design principles that optimize the visualization of sets using linear diagrams. These principles are justified through empirical studies that evaluate the impact of graphical features on...
Crystallization processes in bi-component thin film depositions:
The kinetic Monte Carlo (KMC) method is a powerful and simple tool to simulate the growth of thin films by deposition. However, one of its major drawbacks is the artificial order induced by the use of regular lattices. An...
Sixth Annual Valentine's Day Jewelry Sale Set for Feb. 8
Winthrop University
Jan 01, 0001
The Jewelry and Metals program and GEM (Guild of Emerging Metalsmiths student organization) will host the sixth annual Valentine's Jewelry Sale on Friday, Feb. 8. The noon to 5 p.m. sale on Feb. 8 will take place in the...
Published by: Winthrop University
Fifth Annual Jewelry Sale Held Friday to Tempt Valentine Shoppers
Winthrop University
Jan 01, 0001
GEM will host the Fifth Annual Valentine's Jewelry Sale on Friday, Feb. 3, from noon-5 p.m. in Rutledge Building G20. Created by six student-artists, pieces for sale will include earrings, rings, necklaces and much more.
Published by: Winthrop University
Exploring ICCS 2016 to measure progress toward target 4.7
The objective of this report is to analyse data from the last cycle of the International Civic and Citizenship Study (ICCS 2016) (Schulz et al., 2017) in order to demonstrate its potential for monitoring specific aspects of the...
Published by: UNESCO
Holiday Art Sale Set for Nov. 14
Winthrop University
Jan 01, 0001
The Guild of Emerging Metalsmiths (GEM) and students from the Department of Fine Arts and the College of Business Administration will host the annual Holiday Art Sale on Friday, Nov. 14. The sale will take place in 114 DiGiorgio...
Published by: Winthrop University
Crystallization processes in bi-component thin film depositions:
The kinetic Monte Carlo (KMC) method is a powerful and simple tool to simulate the growth of thin films by deposition. However, one of its major drawbacks is the artificial order induced by the use of regular lattices. An...
How Children Process Reduced Forms
Reduced forms such as the pronoun he provide little information about their intended meaning compared to more elaborate descriptions such as the lead singer of Coldplay. Listeners must therefore use contextual information to...
The Lantern Vol. 41, No. 1, Fall 1974
S. L. Welles, Rebecca J. Henry, David Kenneth Roberts, Kate Swanson, Cindy Poots, Donald R. Whittaker, Gerard J. Mitchell, Jill Leauber, Clint R. Edson, Scott Wagner, Robert Simon, George Bause
Jan 01, 0001
The Fable Landscape - Clear Weather in the Valley Josephine Palooka Don't Bark Twice - It's All Right Masks Suicide Note From a Lemming The Death of Dame Sexton Come September Leaves Spruce Grove The Class...
Ursinus College Collegeville Pennsylvania Lantern Literary Magazine poetry fiction Creative Nonfiction Arts and Humanities Creative Writing fiction illustration Nonfiction poetry
Published by: Ursinus College
Effects of age-related hearing loss and hearing aid experience on sentence processing.
Margreet Vogelzang, Christiane M Thiel, Stephanie Rosemann, Jochem W Rieger, Esther Ruigendijk
May 17, 2021
Age-related hearing loss typically affects the hearing of high frequencies in older adults. Such hearing loss influences the processing of spoken language, including higher-level processing such as that of complex sentences....
The effect of oxygenate fuels on PN emissions from a highly boosted GDI engine
Felix C.P. Leach, Richard Stone, David Richardson, James W.G. Turner, Andrew Lewis, Sam Akehurst, Sarah Remmert, Steven Campbell, Roger Cracknell
Aug 01, 2018
Gasoline Direct Injection (GDI) engines are increasingly available in the market. Such engines are known to emit more Particulate Matter (PM) than their port-fuel injected predecessors. There is also a widespread use of...
Exploring ICCS 2016 to measure progress toward target 4.7
The objective of this report is to analyse data from the last cycle of the International Civic and Citizenship Study (ICCS 2016) (Schulz et al., 2017) in order to demonstrate its potential for monitoring specific aspects of the...
Published by: UNESCO
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