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Metaphysics as a Fundamental Poise
Francisco Vicente Galán Vélez
Mar 16, 2022
Francisco Vicente Galán Vélez is a full-time professor in the philosophy department at the Universidad Iberoamericana in Mexico City. He oversaw the translation of Insight: Estudio sobre la comprensión humana, trad. Francisco...
Published by: Memorial University of Newfoundland
Metaphysics as a Fundamental Poise
Francisco Vicente Galán Vélez
Mar 16, 2022
Francisco Vicente Galán Vélez is a full-time professor in the philosophy department at the Universidad Iberoamericana in Mexico City. He oversaw the translation of Insight: Estudio sobre la comprensión humana, trad. Francisco...
Published by: Memorial University of Newfoundland
Targeting melanoma's MCL1 bias unleashes the apoptotic potential of BRAF and ERK1/2 pathway inhibitors.
Matthew J Sale, Emma Minihane, Noel R Monks, Rebecca Gilley, Frances M Richards, Kevin P Schifferli, Courtney L Andersen, Emma J Davies, Mario Aladren Vicente, Eiko Ozono, Aleksandra Markovets, Jonathan R Dry, Lisa Drew, Vikki Flemington, Theresa Proia, Duncan I Jodrell, Paul D Smith, Simon J Cook
Dec 16, 2019
BRAF and MEK1/2 inhibitors are effective in melanoma but resistance inevitably develops. Despite increasing the abundance of pro-apoptotic BIM and BMF, ERK1/2 pathway inhibition is predominantly cytostatic, reflecting residual...
Targeting melanoma's MCL1 bias unleashes the apoptotic potential of BRAF and ERK1/2 pathway inhibitors.
Matthew J Sale, Emma Minihane, Noel R Monks, Rebecca Gilley, Frances M Richards, Kevin P Schifferli, Courtney L Andersen, Emma J Davies, Mario Aladren Vicente, Eiko Ozono, Aleksandra Markovets, Jonathan R Dry, Lisa Drew, Vikki Flemington, Theresa Proia, Duncan I Jodrell, Paul D Smith, Simon J Cook
Jun 21, 2019
Targeting melanoma’s MCL1 bias unleashes the apoptotic potential of BRAF and ERK1/2 pathway inhibitors
Matthew J. Sale, Emma Minihane, Noel R. Monks, Rebecca Gilley, Frances M. Richards, Kevin P. Schifferli, Courtney L. Andersen, Emma J. Davies, Mario Aladren Vicente, Eiko Ozono, Aleksandra Markovets, Jonathan R. Dry, Lisa Drew, Vikki Flemington, Theresa Proia, Duncan I. Jodrell, Paul D. Smith, Simon J. Cook
Nov 13, 2020
Investigating Epistemic Stances in Game Play with Data Mining
In this paper, techniques of statistical computing were applied to data logs to investigate the patterns in students' play of The Fuzzy Chronicles, and how these patterns relate to learning outcomes with regards to Newtonian...
Published by: IGI Global Scientific Publishing
End-User Approach to Evaluating Costs and Benefits of Smart City Applications
As a part of an ongoing series of studies in the smart city domain from the perspective of end-users, the paper presents the results of an exploratory survey based on the cost-benefit analysis of different smart city solutions...
Published by: IGI Global Scientific Publishing
Behavioural Intention Determinants of Augmented Reality Technology Adoption in Supermarkets/Hypermarkets
In this paper, the adoption of Augmented Reality, as one of the emerging and intriguing digital technologies, has been investigated. This research uses the extended Unified Theory on Acceptance and Use of Technology framework to...
Published by: IGI Global Scientific Publishing
The Impact of Innovative Capabilities and Innovation Types on the Financial Performances of Insurance Companies
The ability to innovate is essential for achieving a competitive position, and digital innovations have become one of the main drivers of competitive advantage. The factors that affect the degree of innovation (innovation...
Published by: IGI Global Scientific Publishing
Distribution of Trapped Magnetic Flux in Superconducting Stacks Magnetised by Angled Field
Abstract: Some novel energy applications require the use of complex shapes of stacks of superconducting tapes as trapped-flux magnets. A trapped-flux magnet magnetised in a superconducting motor may experience an angled...
Heat extraction from HTS tape stacks applied in a superconducting motor in different cooling conditions
Lukasz Tomkow, Nikolay Mineev, Anis Smara, Vicente Climente-Alarcon, Bartek A. Glowacki
Jun 19, 2020
Abstract: The heat is generated inside the stack of superconducting tapes mounted on the surface of the electrical machine rotor during its operation and magnetization. Cooling of such stack presents challenges because of the...
HPG pore
BACKGROUND: The use of nanopore technologies is expected to spread in the future because they are portable and can sequence long fragments of DNA molecules without prior amplification. The first nanopore sequencer available, the...
Mapping the expression of transient receptor potential channels across murine placental development
Katrien De Clercq, Vicente Pérez-García, Rieta Van Bree, Federica Pollastro, Karen Peeraer, Thomas Voets, Joris Vriens
Jun 26, 2021
Nestin(+) cells direct inflammatory cell migration in atherosclerosis.
Raquel Del Toro, Raphael Chèvre, Cristina Rodríguez, Antonio Ordóñez, José Martínez-González, Vicente Andrés, Simón Méndez-Ferrer
Aug 23, 2016
Decidualisation and placentation defects are a major cause of age-related reproductive decline.
Laura Woods, Vicente Perez-Garcia, Jens Kieckbusch, Xiaoqiu Wang, Francesco DeMayo, Francesco Colucci, Myriam Hemberger
Dec 17, 2018
Distribution of Trapped Magnetic Flux in Superconducting Stacks Magnetised by Angled Field
Abstract: Some novel energy applications require the use of complex shapes of stacks of superconducting tapes as trapped-flux magnets. A trapped-flux magnet magnetised in a superconducting motor may experience an angled...
Cryo-EM structure of metazoan TRAPPIII, the multi-subunit complex that activates the GTPase Rab1.
The TRAPP complexes are nucleotide exchange factors that play essential roles in membrane traffic and autophagy. TRAPPII activates Rab11, and TRAPPIII activates Rab1, with the two complexes sharing a core of small subunits that...
Mapping the expression of transient receptor potential channels across murine placental development.
Katrien De Clercq, Vicente Pérez-García, Rieta Van Bree, Federica Pollastro, Karen Peeraer, Thomas Voets, Joris Vriens
Jul 07, 2021
placental development Primary trophoblast cells TRP channels trophoblast stem cells Animals Calcium Channels Calcium Signaling Cell Differentiation Cell Proliferation Female Gene Expression Regulation Mice Mice Inbred C57BL Mouse embryonic stem cells Placenta Placentation Pregnancy Stem Cells TRPV Cation Channels Transient Receptor Potential Channels Trophoblasts
Descriptive and Quasi-Experimental Studies about Moral Emotions, Online Empathy, Anger Management, and Their Relations with Key Competencies in Primary Education.
BACKGROUND: Antisocial behaviours make social interactions difficult among students. Moral emotions, online empathy, and anger management are social and emotional variables related to prosocial and antisocial behaviours and...
Frequency-dependent demagnetisation rate of a shielded HTS tape stack
Lukasz Tomkow, Vicente Climente-Alarcon, Nikolay Mineev, Anis Smara, Bartek A. Glowacki
Jun 19, 2020
Abstract: This work presents results of investigation of crossed-field demagnetization in 2G high temperature superconducting stacks at temperatures in the range of 77 - 20 K and in a variable frequency, corresponding to the...
Ars moriendi
Mario O. D’Souza
Mar 14, 2018
I first found out that I have cancer, and the level of its severity and advanced stage,on the 11th of July, 2017. I had some symptoms like shortness of breath andfatigue, but I attributed them to a pill that I was taking, and...
Published by: Memorial University of Newfoundland
G. William Bouldin, More Than a Businessman
Mario M. Gutierrez
Apr 01, 2020
When the average person thinks about African American history, the two major historical subjects that possibly comes to their mind are slavery and the civil rights movement. I believe this is the case because African American...
Published by: Digital Commons @ Texas A&M University-San Antonio
Myosin-Like Proteins in S. cerevisiae: Multifunctional, Structural Components of the Nuclear Envelope
Mario Niepel
Jan 01, 0001
The nuclear envelope (NE) separates the genetic material from the rest of the cell, delimits and defines the nucleus, organizes the intranuclear architecture and serves as a regulator for multiple nuclear processes. In all...
Nuclear Envelope Mlp proteins nuclear transport nuclear pore complex Yeast spindle pole body Life Sciences
Published by: Rockefeller University
Horizontal gene transfer in human pathogens.
Mario Juhas
Jul 23, 2013
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