Search
Results: 18
Heterogeneity in glucose response curves during an oral glucose tolerance test and associated cardiometabolic risk.
Adam Hulman, Rebecca K Simmons, Dorte Vistisen, Adam G Tabák, Jacqueline M Dekker, Marjan Alssema, Femke Rutters, Anitra DM Koopman, Thomas PJ Solomon, John P Kirwan, Torben Hansen, Anna Jonsson, Anette Prior Gjesing, Hans Eiberg, Arne Astrup, Oluf Pedersen, Thorkild IA Sørensen, Daniel R Witte, Kristine Færch
May 16, 2018
An Algorithm for Multi-Domain Website Classification
The web is the largest world-wide communication system of computers. The web has local, academic, commercial and government sites. As the types of websites increases in numbers, the cost and accuracy of manual classification...
Published by: IGI Global Scientific Publishing
A cross sectional study of impact and clinical risk factors of antipsychotic-induced OCD.
Marjan Biria, Fiona-Xiaofei Huang, Yulia Worbe, Naomi A Fineberg, Trevor W Robbins, Emilio Fernandez-Egea
Jun 17, 2019
Developing Non-Laboratory Cardiovascular Risk Assessment Charts and Validating Laboratory and Non-Laboratory-Based Models.
Razieh Hassannejad, Marjan Mansourian, Hamidreza Marateb, Mohammad Reza Mohebian, Thomas Andrew Gaziano, Rodney T Jackson, Emanuele Di Angelantonio, Nizal Sarrafzadegan
Jan 06, 2022
BACKGROUND: Developing simplified risk assessment model based on non-laboratory risk factors that could determine cardiovascular risk as accurately as laboratory-based one can be valuable, particularly in developing countries...
Exceptional ancient DNA preservation and fibre remains of a Sasanian saltmine sheep mummy in Chehrābād, Iran
Exceptional ancient DNA preservation and fibre remains of a Sasanian saltmine sheep mummy in Chehrābād, Iran.
Conor Rossi, Gabriela Ruß-Popa, Valeria Mattiangeli, Fionnuala McDaid, Andrew J Hare, Hossein Davoudi, Haeedeh Laleh, Zahra Lorzadeh, Roya Khazaeli, Homa Fathi, Matthew D Teasdale, Abolfazl A'ali, Thomas Stöllner, Marjan Mashkour, Kevin G Daly
Jul 16, 2021
Mummified remains have long attracted interest as a potential source of ancient DNA. However, mummification is a rare process that requires an anhydrous environment to rapidly dehydrate and preserve tissue before complete...
A Randomized Trial Directly Comparing Ventral Capsule and Anteromedial Subthalamic Nucleus Stimulation in Obsessive-Compulsive Disorder
Himanshu Tyagi, Annemieke M Apergis-Schoute, Harith Akram, Tom Foltynie, Patricia Limousin, Lynne M Drummond, Naomi A Fineberg, Keith Matthews, Marjan Jahanshahi, Trevor W Robbins, Barbara J Sahakian, Ludvic Zrinzo, Marwan Hariz, Eileen M Joyce
May 07, 2019
BACKGROUND: Deep brain stimulation (DBS) is an emerging treatment for severe obsessive-compulsive disorder (OCD). We compared the efficacy of ventral capsule/ventral striatal (VC/VS) and anteromedial subthalamic nucleus (amSTN)...
Anteromedial subthalamic nucleus DBS Deep Brain Stimulation OCD Obsessive-Compulsive Disorder Ventral internal capsule Adult Deep Brain Stimulation Double-Blind Method Female Humans Magnetic Resonance Imaging Male Middle Aged Obsessive-Compulsive Disorder Subthalamic nucleus Treatment Outcome Ventral Striatum
Salmonella enterica Serovar Typhi Lipopolysaccharide O-Antigen Modification Impact on Serum Resistance and Antibody Recognition.
Erica Kintz, Christian Heiss, Ian Black, Nicholas Donohue, Naj Brown, Mark R Davies, Parastoo Azadi, Stephen Baker, Paul M Kaye, Marjan van der Woude
Apr 10, 2019
Salmonella enterica serovar Typhi is a human-restricted Gram-negative bacterial pathogen responsible for causing an estimated 27 million cases of typhoid fever annually, leading to 217,000 deaths, and current vaccines do not...
O-antigen Salmonella enterica LIPOPOLYSACCHARIDE phase variation serum resistance Animals Antibodies Bacterial Bacterial Proteins Base Sequence Disease Models Animal Female Gene Expression Regulation Bacterial Humans Immune Sera Immunization Methylation Mice O Antigens Operon Salmonella typhi Typhoid Fever
Coding and regulatory variants are associated with serum protein levels and disease.
Valur Emilsson, Valborg Gudmundsdottir, Alexander Gudjonsson, Thorarinn Jonmundsson, Brynjolfur G Jonsson, Mohd A Karim, Marjan Ilkov, James R Staley, Elias F Gudmundsson, Lenore J Launer, Jan H Lindeman, Nicholas M Morton, Thor Aspelund, John R Lamb, Lori L Jennings, Vilmundur Gudnason
Feb 26, 2022
Circulating proteins can be used to diagnose and predict disease-related outcomes. A deep serum proteome survey recently revealed close associations between serum protein networks and common disease. In the current study, 54,469...
Coding and regulatory variants are associated with serum protein levels and disease.
Valur Emilsson, Valborg Gudmundsdottir, Alexander Gudjonsson, Thorarinn Jonmundsson, Brynjolfur G Jonsson, Mohd A Karim, Marjan Ilkov, James R Staley, Elias F Gudmundsson, Lenore J Launer, Jan H Lindeman, Nicholas M Morton, Thor Aspelund, John R Lamb, Lori L Jennings, Vilmundur Gudnason
Jan 28, 2022
Circulating proteins can be used to diagnose and predict disease-related outcomes. A deep serum proteome survey recently revealed close associations between serum protein networks and common disease. In the current study, 54,469...
Proteomic, biomechanical and functional analyses define neutrophil heterogeneity in systemic lupus erythematosus.
Kathleen R Bashant, Angel M Aponte, Davide Randazzo, Paniz Rezvan Sangsari, Alexander Jt Wood, Jack A Bibby, Erin E West, Arlette Vassallo, Zerai G Manna, Martin P Playford, Natasha Jordan, Sarfaraz Hasni, Marjan Gucek, Claudia Kemper, Andrew Conway Morris, Nicole Y Morgan, Nicole Toepfner, Jochen Guck, Nehal N Mehta, Edwin R Chilvers, Charlotte Summers, Mariana J Kaplan
Aug 24, 2020
OBJECTIVES: Low-density granulocytes (LDGs) are a distinct subset of proinflammatory and vasculopathic neutrophils expanded in systemic lupus erythematosus (SLE). Neutrophil trafficking and immune function are intimately linked...
Tracking the Near Eastern origins and European dispersal of the western house mouse
Thomas Cucchi, Katerina Papayianni, Sophie Cersoy, Laetitia Aznar-Cormano, Antoine Zazzo, Régis Debruyne, Rémi Berthon, Adrian Bălășescu, Alan Simmons, François Valla, Yannis Hamilakis, Fanis Mavridis, Marjan Mashkour, Jamshid Darvish, Roohollah Siahsarvi, Fereidoun Biglari, Cameron A. Petrie, Lloyd Weeks, Alireza Sardari, Sepideh Maziar, Christiane Denys, David Orton, Emma Jenkins, Melinda Zeder, Jeremy B. Searle, Greger Larson, François Bonhomme, Jean-Christophe Auffray, Jean-Denis Vigne
May 20, 2021
Abstract: The house mouse (Mus musculus) represents the extreme of globalization of invasive mammals. However, the timing and basis of its origin and early phases of dispersal remain poorly documented. To track its...
Tracking the Near Eastern origins and European dispersal of the western house mouse.
Thomas Cucchi, Katerina Papayianni, Sophie Cersoy, Laetitia Aznar-Cormano, Antoine Zazzo, Régis Debruyne, Rémi Berthon, Adrian Bălășescu, Alan Simmons, François Valla, Yannis Hamilakis, Fanis Mavridis, Marjan Mashkour, Jamshid Darvish, Roohollah Siahsarvi, Fereidoun Biglari, Cameron A Petrie, Lloyd Weeks, Alireza Sardari, Sepideh Maziar, Christiane Denys, David Orton, Emma Jenkins, Melinda Zeder, Jeremy B Searle, Greger Larson, François Bonhomme, Jean-Christophe Auffray, Jean-Denis Vigne
Jul 06, 2020
The house mouse (Mus musculus) represents the extreme of globalization of invasive mammals. However, the timing and basis of its origin and early phases of dispersal remain poorly documented. To track its synanthropisation and...
Proteomic, biomechanical and functional analyses define neutrophil heterogeneity in systemic lupus erythematosus
Kathleen R Bashant, Angel M Aponte, Davide Randazzo, Paniz Rezvan Sangsari, Alexander Jt Wood, Jack A Bibby, Erin E West, Arlette Vassallo, Zerai G Manna, Martin P Playford, Natasha Jordan, Sarfaraz Hasni, Marjan Gucek, Claudia Kemper, Andrew Conway Morris, Nicole Y Morgan, Nicole Toepfner, Jochen Guck, Nehal N Mehta, Edwin R Chilvers, Charlotte Summers, Mariana J Kaplan
Sep 30, 2020
Glycoproteomic Analysis of the Aortic Extracellular Matrix in Marfan Patients.
Xiaoke Yin 殷晓科, Shaynah Wanga, Adam L Fellows, Javier Barallobre-Barreiro, Ruifang Lu, Hongorzul Davaapil, Romy Franken, Marika Fava, Ferheen Baig, Philipp Skroblin, Qiuru Xing, David R Koolbergen, Maarten Groenink, Aeilko H Zwinderman, Ron Balm, Carlie JM de Vries, Barbara JM Mulder, Rosa Viner, Marjan Jahangiri, Dieter P Reinhardt, Sanjay Sinha, Vivian de Waard, Manuel Mayr
Jul 25, 2019
OBJECTIVE: Marfan syndrome (MFS) is caused by mutations in FBN1 (fibrillin-1), an extracellular matrix (ECM) component, which is modified post-translationally by glycosylation. This study aimed to characterize the glycoproteome...
A cellular census of human lungs identifies novel cell states in health and in asthma.
Felipe A Vieira Braga, Gozde Kar, Marijn Berg, Orestes A Carpaij, Krzysztof Polanski, Lukas M Simon, Sharon Brouwer, Tomás Gomes, Laura Hesse, Jian Jiang, Eirini S Fasouli, Mirjana Efremova, Roser Vento-Tormo, Carlos Talavera-López, Marnix R Jonker, Karen Affleck, Subarna Palit, Paulina M Strzelecka, Helen V Firth, Krishnaa T Mahbubani, Ana Cvejic, Kerstin B Meyer, Kourosh Saeb-Parsy, Marjan Luinge, Corry-Anke Brandsma, Wim Timens, Ilias Angelidis, Maximilian Strunz, Gerard H Koppelman, Antoon J van Oosterhout, Herbert B Schiller, Fabian J Theis, Maarten van den Berge, Martijn C Nawijn, Sarah A Teichmann
May 03, 2019
Ancient goat genomes reveal mosaic domestication in the Fertile Crescent.
Kevin G Daly, Pierpaolo Maisano Delser, Victoria E Mullin, Amelie Scheu, Valeria Mattiangeli, Matthew D Teasdale, Andrew J Hare, Joachim Burger, Marta Pereira Verdugo, Matthew J Collins, Ron Kehati, Cevdet Merih Erek, Guy Bar-Oz, François Pompanon, Tristan Cumer, Canan Çakırlar, Azadeh Fatemeh Mohaseb, Delphine Decruyenaere, Hossein Davoudi, Özlem Çevik, Gary Rollefson, Jean-Denis Vigne, Roya Khazaeli, Homa Fathi, Sanaz Beizaee Doost, Roghayeh Rahimi Sorkhani, Ali Akbar Vahdati, Eberhard W Sauer, Hossein Azizi Kharanaghi, Sepideh Maziar, Boris Gasparian, Ron Pinhasi, Louise Martin, David Orton, Benjamin S Arbuckle, Norbert Benecke, Andrea Manica, Liora Kolska Horwitz, Marjan Mashkour, Daniel G Bradley
Nov 29, 2018
Current genetic data are equivocal as to whether goat domestication occurred multiple times or was a singular process. We generated genomic data from 83 ancient goats (51 with genome-wide coverage) from Paleolithic to Medieval...
Multi-ancestry sleep-by-SNP interaction analysis in 126,926 individuals reveals lipid loci stratified by sleep duration.
Raymond Noordam, Maxime M Bos, Heming Wang, Thomas W Winkler, Amy R Bentley, Tuomas O Kilpeläinen, Paul S de Vries, Yun Ju Sung, Karen Schwander, Brian E Cade, Alisa Manning, Hugues Aschard, Michael R Brown, Han Chen, Nora Franceschini, Solomon K Musani, Melissa Richard, Dina Vojinovic, Stella Aslibekyan, Traci M Bartz, Lisa de Las Fuentes, Mary Feitosa, Andrea R Horimoto, Marjan Ilkov, Minjung Kho, Aldi Kraja, Changwei Li, Elise Lim, Yongmei Liu, Dennis O Mook-Kanamori, Tuomo Rankinen, Salman M Tajuddin, Ashley van der Spek, Zhe Wang, Jonathan Marten, Vincent Laville, Maris Alver, Evangelos Evangelou, Maria E Graff, Meian He, Brigitte Kühnel, Leo-Pekka Lyytikäinen, Pedro Marques-Vidal, Ilja M Nolte, Nicholette D Palmer, Rainer Rauramaa, Xiao-Ou Shu, Harold Snieder, Stefan Weiss, Wanqing Wen, Lisa R Yanek, Correa Adolfo, Christie Ballantyne, Larry Bielak, Nienke R Biermasz, Eric Boerwinkle, Niki Dimou, Gudny Eiriksdottir, Chuan Gao, Sina A Gharib, Daniel J Gottlieb, José Haba-Rubio, Tamara B Harris, Sami Heikkinen, Raphaël Heinzer, James E Hixson, Georg Homuth, M Arfan Ikram, Pirjo Komulainen, Jose E Krieger, Jiwon Lee, Jingmin Liu, Kurt K Lohman, Annemarie I Luik, Reedik Mägi, Lisa W Martin, Thomas Meitinger, Andres Metspalu, Yuri Milaneschi, Mike A Nalls, Jeff O'Connell, Annette Peters, Patricia Peyser, Olli T Raitakari, Alex P Reiner, Patrick CN Rensen, Treva K Rice, Stephen S Rich, Till Roenneberg, Jerome I Rotter, Pamela J Schreiner, James Shikany, Stephen S Sidney, Mario Sims, Colleen M Sitlani, Tamar Sofer, Konstantin Strauch, Morris A Swertz, Kent D Taylor, André G Uitterlinden, Cornelia M van Duijn, Henry Völzke, Melanie Waldenberger, Robert B Wallance, Ko Willems van Dijk, Caizheng Yu, Alan B Zonderman, Diane M Becker, Paul Elliott, Tõnu Esko, Christian Gieger, Hans J Grabe, Timo A Lakka, Terho Lehtimäki, Kari E North, Brenda WJH Penninx, Peter Vollenweider, Lynne E Wagenknecht, Tangchun Wu, Yong-Bing Xiang, Wei Zheng, Donna K Arnett, Claude Bouchard, Michele K Evans, Vilmundur Gudnason, Sharon Kardia, Tanika N Kelly, Stephen B Kritchevsky, Ruth JF Loos, Alexandre C Pereira, Mike Province, Bruce M Psaty, Charles Rotimi, Xiaofeng Zhu, Najaf Amin, L Adrienne Cupples, Myriam Fornage, Ervin F Fox, Xiuqing Guo, W James Gauderman, Kenneth Rice, Charles Kooperberg, Patricia B Munroe, Ching-Ti Liu, Alanna C Morrison, Dabeeru C Rao, Diana van Heemst, Susan Redline
Feb 07, 2020
Both short and long sleep are associated with an adverse lipid profile, likely through different biological pathways. To elucidate the biology of sleep-associated adverse lipid profile, we conduct multi-ancestry genome-wide...