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Feline Calicivirus Infection Disrupts Assembly of Cytoplasmic Stress Granules and Induces G3BP1 Cleavage.
Majid N Humoud, Nicole Doyle, Elizabeth Royall, Margaret M Willcocks, Frederic Sorgeloos, Frank van Kuppeveld, Lisa O Roberts, Ian G Goodfellow, Martijn A Langereis, Nicolas Locker
Nov 20, 2017
UNLABELLED: In response to stress such as virus infection, cells can stall translation by storing mRNAs away in cellular compartments called stress granules (SGs). This defense mechanism favors cell survival by limiting the use...
3C Viral Proteases Animals Caliciviridae Infections calicivirus Feline Carrier Proteins Cats Cysteine Endopeptidases Cytoplasmic Granules DNA Helicases Eukaryotic Initiation Factor-2 HeLa Cells Host-Pathogen Interactions Humans Mitogen-Activated Protein Kinases Phosphorylation Poly-ADP-Ribose Binding Proteins RNA Helicases RNA Recognition Motif Proteins Viral Proteins Virus Replication
Erythrocytes lacking the Langereis blood group protein ABCB6 are resistant to the malaria parasite Plasmodium falciparum.
Elizabeth S Egan, Michael P Weekes, Usheer Kanjee, Jale Manzo, Ashwin Srinivasan, Christine Lomas-Francis, Connie Westhoff, Junko Takahashi, Mitsunobu Tanaka, Seishi Watanabe, Carlo Brugnara, Steven P Gygi, Yoshihiko Tani, Manoj T Duraisingh
Jun 25, 2018
The ATP-binding cassette transporter ABCB6 was recently discovered to encode the Langereis (Lan) blood group antigen. Lan null individuals are asymptomatic, and the function of ABCB6 in mature erythrocytes is not understood....
Effect of Technological Insecurity on Performance Through Emotional Exhaustion
Martijn Jungst
Jan 01, 2022
The new digital age introduces a continuous stream of technological innovations. Yet, little is known about how these technological innovations influence workplace behavior. Drawing on the stressor-strain model, this study...
Published by: IGI Global Scientific Publishing
A Method for Rapid Ethical Deliberation in Research and Innovation Projects
There are many and diverse methods available that can help researchers, designers, developers, and engineers integrate ethics in their research and innovation projects. In practice, however, they can find this challenging. They...
Published by: IGI Global Scientific Publishing
The association between depressive symptoms in the community, non-psychiatric hospital admission and hospital outcomes
A Matthew Prina, Theodore D Cosco, Tom Dening, Aartjan Beekman, Carol Brayne, Martijn Huisman
Dec 17, 2014
High-flow nasal oxygen vs. standard oxygen therapy for patients undergoing transcatheter aortic valve replacement with conscious sedation
S Scheuermann, A Tan, P Govender, M Mckie, J Pack, G Martinez, F Falter, S George, A A. Klein
Apr 14, 2023
Discordant attributes of structural and functional brain connectivity in a two-layer multiplex network.
Several studies have suggested that functional connectivity (FC) is constrained by the underlying structural connectivity (SC) and mutually correlated. However, not many studies have focused on differences in the network...
The Effect of Leader-Member Exchange on Voice
The new digital age introduces new challenges and opportunities for leaders to engage their followers in voice behavior. Drawing on the conservation of resources theory, the objective of this paper is to examine the mediating...
Published by: IGI Global Scientific Publishing
Optimized design and assessment of whole genome tiling arrays.
Stefan Gräf, Fiona GG Nielsen, Stefan Kurtz, Martijn A Huynen, Ewan Birney, Henk Stunnenberg, Paul Flicek
Sep 23, 2019
MOTIVATION: Recent advances in microarray technologies have made it feasible to interrogate whole genomes with tiling arrays and this technique is rapidly becoming one of the most important high-throughput functional genomics...
Competitive Frontoparietal Interactions Mediate Implicit Inferences.
Frequent experience with regularities in our environment allows us to use predictive information to guide our decision process. However, contingencies in our environment are not always explicitly present and sometimes need to be...
How does fiction reading influence empathy? An experimental investigation on the role of emotional transportation
The current study investigated whether fiction experiences change empathy of the reader. Based on transportation theory, it was predicted that when people read fiction, and they are emotionally transported into the story, they...
Achieving robustness to aleatoric uncertainty with heteroscedastic Bayesian optimisation
Ryan-Rhys Griffiths, Alexander A Aldrick, Miguel Garcia-Ortegon, Vidhi Lalchand, Alpha A Lee
Nov 23, 2021
Abstract: Bayesian optimisation is a sample-efficient search methodology that holds great promise for accelerating drug and materials discovery programs. A frequently-overlooked modelling consideration in Bayesian optimisation...
Action information contributes to metacognitive decision-making
Abstract: Metacognitive abilities allow us to adjust ongoing behavior and modify future decisions in the absence of external feedback. Although metacognition is critical in many daily life settings, it remains unclear what...
Action information contributes to metacognitive decision-making.
Metacognitive abilities allow us to adjust ongoing behavior and modify future decisions in the absence of external feedback. Although metacognition is critical in many daily life settings, it remains unclear what information is...
Group 2 innate lymphocytes at the interface between innate and adaptive immunity.
Group 2 innate lymphoid cells (ILC2) are innate immune cells that respond rapidly to their environment through soluble inflammatory mediators and cell-to-cell interactions. As tissue-resident sentinels, ILC2 help orchestrate...
ILC2 T helper cells TH2 innate lymphoid cells type 2 response Adaptive Immunity Animals Cell Differentiation Cytokines Hormones Humans Immunity Innate Interleukins Lipids Lymphocyte Activation Lymphocyte Subsets Mice Models Immunological Neuroimmunomodulation Organ Specificity Receptors Immunologic Thymic Stromal Lymphopoietin
Air-stable photoconductive films formed from perylene bisimide gelators
Emily R. Draper, James J . Walsh, Tom O. McDonald, Martijn A. Zwijnenburg, Petra J. Cameron, Alexander J. Cowan, D. J. Adams
Jul 28, 2014
We show that amino acid-PBIs can form one-dimensional structures at high pH and then gels at low pH. Both the dried solutions and dried gels are photoconductive. Interestingly, photoconductivity of these materials requires that...
Prism Adaptation in Rehabilitation? No Additional Effects of Prism Adaptation on Neglect Recovery in the Subacute Phase Poststroke
Antonia F. Ten Brink, Johanna M a Visser-Meily, Martijn J. Schut, Mirjam Kouwenhoven, Anja L H Eijsackers, Tanja C.W. Nijboer
Dec 01, 2017
Background. Patients with neglect ignore or respond slower to contralesional stimuli. Neglect negatively influences independence in activities of daily living (ADL). Prism adaptation (PA) is one of the most frequently studied...
How does fiction reading influence empathy? An experimental investigation on the role of emotional transportation
The current study investigated whether fiction experiences change empathy of the reader. Based on transportation theory, it was predicted that when people read fiction, and they are emotionally transported into the story, they...
Depression amongst interns working in a tertiary care teaching Hospital in Maharashtra
Background: Internship is a crucial stage of medical school regarding student stress which can affect the patient care negatively. Retrieving knowledge about presence of depression is therefore important in itself and if found...
Published by: IJHS Medical Association
Green spaces, subjective health and depressed affect in middle-aged and older adults
J Mark Noordzij, Marielle A Beenackers, Joost Oude Groeniger, Erik Timmermans, Basile Chaix, Dany Doiron, Martijn Huisman, Irina Motoc, Milagros Ruiz, Rita Wissa, Mauricio Avendano, Frank J van Lenthe
Jan 29, 2021
BACKGROUND: Studies on associations between urban green space and mental health have yielded mixed results. This study examines associations of green space exposures with subjective health and depressed affect of middle-aged and...
A Model of Cloud Forensic Application With Assurance of Cloud Log
The key concepts of digital forensic investigation in cloud computing are examination and investigation. Cybercriminals target cloud-based web applications due to presence of vulnerabilities. Forensic investigation is a complex...
Published by: IGI Global Scientific Publishing
Depression amongst interns working in a tertiary care teaching Hospital in Maharashtra
Background: Internship is a crucial stage of medical school regarding student stress which can affect thepatient care negatively. Retrieving knowledge about presence of depression is therefore important in itself and iffound...
Published by: IJHS Medical Association
Improving the soundscape quality of urban areas exposed to aircraft noise by adding moving water and vegetation.
Sentiment Analysis on Movie Reviews Dataset Using Support Vector Machines and Ensemble Learning
The internet makes it easier for people to connect to each other and has become a platform to express ideas and share information with the world. The growth of the internet has indirectly led to the development of social...
Published by: IGI Global Scientific Publishing
Right sided eventration of diaphragm with clinodactyly
A. Sareen and K. Mahajan
Apr 21, 2015
Diaphragmatic hernia can be of two types-absence or deficiency of the diaphragm, or eventration resulting in elevation of a portion of the diaphragm as a result of incomplete muscularization. Complete eventration almost...
Published by: IJHS Medical Association
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