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Results: 26
Early Investigational and Experimental Therapeutics for the Treatment of Hypertriglyceridemia.
Hypertriglyceridemia has been identified as a risk factor for cardiovascular disease and acute pancreatitis. To date, there are only few drug classes targeting triglyceride levels such as fibrates and ω-3 fatty acids. These...
Early Investigational and Experimental Therapeutics for the Treatment of Hypertriglyceridemia.
Hypertriglyceridemia has been identified as a risk factor for cardiovascular disease and acute pancreatitis. To date, there are only few drug classes targeting triglyceride levels such as fibrates and ω-3 fatty acids. These...
Are Students Actually Learning What You Think They Are? An Exploration Into the Educational Outcomes of Course Based Undergraduate Research Labs
It is important to understand whether students are acquiring intended educational objectives. A course-based undergraduate research experience (CURE) lab seeks to blend the logistical ease and accessibility of college courses...
course-based undergraduate research experience CURE assessment tools science education research outcomes assessment science identity science enculturation Biology Educational Assessment, Evaluation, and Research Life Sciences Physical Sciences and Mathematics
Published by: Ursinus College
The Effect of Self-Service Technologies on Customer Experiences in Banking
The surge in self-service technologies (SSTs) adoption in the banking industries across the globe has changed customers' banking experiences. Customers have developed a passion for SSTs which has affects their intentions to save...
Published by: IGI Global Scientific Publishing
Family Function and Child Adjustment Difficulties in the COVID-19 Pandemic
Sarah Foley, Farzaneh Badinlou, Karin C Brocki, Matilda A Frick, Luca Ronchi, Claire Hughes
Oct 24, 2021
To estimate specific proximal and distal effects of COVID-19-related restrictions on families on children's adjustment problems, we conducted a six-site international study. In total, 2516 parents from Australia, China, Italy...
Interactions between hippocampal activity and striatal dopamine in people at clinical high risk for psychosis
Gemma Modinos, Anja Richter, Alice Egerton, Ilaria Bonoldi, Matilda Azis, Mathilde Antoniades, Matthijs Bossong, Nicolas Crossley, Jesus Perez, James M Stone, Mattia Veronese, Fernando Zelaya, Anthony A Grace, Oliver D Howes, Paul Allen, Philip McGuire
Jun 17, 2021
Preclinical models propose that increased hippocampal activity drives subcortical dopaminergic dysfunction and leads to psychosis-like symptoms and behaviors. Here, we used multimodal neuroimaging to examine the relationship...
Impairments in goal-directed action and reversal learning in a proportion of individuals with psychosis.
Shuichi Suetani, Andrea Baker, Kelly Garner, Peter Cosgrove, Matilda Mackay-Sim, Dan Siskind, Graham K Murray, James G Scott, James P Kesby
Nov 01, 2022
Novel PLCG2 Mutation in a Patient With APLAID and Cutis Laxa.
João Farela Neves, Rainer Doffinger, Gabriela Barcena-Morales, Catarina Martins, Olivier Papapietro, Vincent Plagnol, James Curtis, Marta Martins, Dinakantha Kumararatne, Ana Isabel Cordeiro, Conceição Neves, Luis Miguel Borrego, Matilda Katan, Sergey Nejentsev
Jan 09, 2019
Background: The auto-inflammation and phospholipase Cγ2 (PLCγ2)-associated antibody deficiency and immune dysregulation (APLAID) syndrome is a rare primary immunodeficiency caused by a gain-of-function mutation S707Y in the...
APLAID IL-10 IL-1b PLCγ2 auto-inflammatory syndromes cutis laxa sensorineural deafness Amino Acid Sequence Base Sequence Cutis Laxa DNA Mutational Analysis Female Hereditary Autoinflammatory Diseases Humans Immunologic Deficiency Syndromes Infant Newborn Inflammatory Bowel Diseases Male Mutation Missense Pedigree Phospholipase C gamma Sequence Homology Amino Acid
Inhibitory control and problem solving in early childhood
Alexandra Hendry, Mary A Agyapong, Hana D'Souza, Matilda A Frick, Ana Maria Portugal, Linn Andersson Konke, Hamish Cloke, Rachael Bedford, Tim J Smith, Annette Karmiloff-Smith, Emily JH Jones, Tony Charman, Karin C Brocki
Sep 18, 2022
Low inhibitory control (IC) is sometimes associated with enhanced problem-solving amongst adults, yet for young children high IC is primarily framed as inherently better than low IC. Here, we explore associations between IC and...
Glutamatergic and dopaminergic function and the relationship to outcome in people at clinical high risk of psychosis
Oliver D Howes, Ilaria Bonoldi, Robert A McCutcheon, Matilda Azis, Mathilde Antoniades, Matthijs Bossong, Gemma Modinos, Jesus Perez, James M Stone, Barbara Santangelo, Mattia Veronese, Anthony Grace, Paul Allen, Philip K McGuire
Oct 15, 2020
Inhibitory control and problem solving in early childhood
Alexandra Hendry, Mary A Agyapong, Hana D'Souza, Matilda A Frick, Ana Maria Portugal, Linn Andersson Konke, Hamish Cloke, Rachael Bedford, Tim J Smith, Annette Karmiloff-Smith, Emily JH Jones, Tony Charman, Karin C Brocki
Jan 10, 2022
Serum metabolome associated with severity of acute traumatic brain injury.
Ilias Thomas, Alex M Dickens, Jussi P Posti, Endre Czeiter, Daniel Duberg, Tim Sinioja, Matilda Kråkström, Isabel RA Retel Helmrich, Kevin KW Wang, Andrew IR Maas, Ewout W Steyerberg, David K Menon, Olli Tenovuo, Tuulia Hyötyläinen, András Büki, Matej Orešič, CENTER-TBI Participants and Investigators
Jun 11, 2022
Complex metabolic disruption is a crucial aspect of the pathophysiology of traumatic brain injury (TBI). Associations between this and systemic metabolism and their potential prognostic value are poorly understood. Here, we...
Natural Progression of Left Ventricular Function following Anthracyclines without Cardioprotective Therapy
Ainsley Ryan Yan Bin Lee, Chun En Yau, Chen Ee Low, Jiaqi Li, Sara Moiz Tyebally, Weiqin Lin, Li-Ling Tan, Chia-Te Liao, Wei-Ting Chang, Matilda Xinwei Lee, Chieh-Yang Koo, Ching-Hui Sia
Feb 03, 2023
Serum metabolome associated with severity of acute traumatic brain injury.
Ilias Thomas, Alex M Dickens, Jussi P Posti, Endre Czeiter, Daniel Duberg, Tim Sinioja, Matilda Kråkström, Isabel RA Retel Helmrich, Kevin KW Wang, Andrew IR Maas, Ewout W Steyerberg, David Menon, Olli Tenovuo, Tuulia Hyötyläinen, András Büki, Matej Orešič, CENTER-TBI Participants and Investigators
May 10, 2022
Complex metabolic disruption is a crucial aspect of the pathophysiology of traumatic brain injury (TBI). Associations between this and systemic metabolism and their potential prognostic value are poorly understood. Here, we...
Natural Progression of Left Ventricular Function following Anthracyclines without Cardioprotective Therapy
Ainsley Ryan Yan Bin Lee, Chun En Yau, Chen Ee Low, Jiaqi Li, Sara Moiz Tyebally, Weiqin Lin, Li-Ling Tan, Chia-Te Liao, Wei-Ting Chang, Matilda Xinwei Lee, Chieh-Yang Koo, Ching-Hui Sia
Feb 21, 2023
BACKGROUND: Anthracyclines form the backbone of many systemic chemotherapy regimens but are accompanied by dose-limiting cardiotoxicity. We elucidate the progression and severity of cardiac function over time, in the absence of...
Deep brain stimulation for refractory obsessive-compulsive disorder (OCD)
Hemmings Wu, Marwan Hariz, Veerle Visser-Vandewalle, Ludvic Zrinzo, Volker A. Coenen, Sameer A. Sheth, Chris Bervoets, Matilda Naesström, Patric Blomstedt, Terry Coyne, Clement Hamani, Konstantin Slavin, Joachim K. Krauss, Kai G. Kahl, Takaomi Taira, Chencheng Zhang, Bomin Sun, Hiroki Toda, Thomas Schlaepfer, Jin Woo Chang, Jean Régis, Rick Schuurman, Michael Schulder, Paresh Doshi, Philip Mosley, Anujan Poologaindran, Gabriel Lázaro-Muñoz, Joshua Pepper, Gaston Schechtmann, Anders Fytagoridis, Daniel Huys, Antonio Gonçalves-Ferreira, Pierre-François D’Haese, Joseph Neimat, Giovanni Broggi, Osvaldo Vilela-Filho, Jürgen Voges, Ahmed Alkhani, Takeshi Nakajima, Raphaelle Richieri, Diana Djurfeldt, Philippe Fontaine, Roberto Martinez-Alvarez, Yasushi Okamura, Jennifer Chandler, Katsushige Watanabe, Juan A. Barcia, Blanca Reneses, Andres Lozano, Loes Gabriëls, Antonio De Salles, Casey H. Halpern, Keith Matthews, Joseph J. Fins, Bart Nuttin
Jan 19, 2021
Abstract: A consensus has yet to emerge whether deep brain stimulation (DBS) for treatment-refractory obsessive-compulsive disorder (OCD) can be considered an established therapy. In 2014, the World Society for Stereotactic and...
Cells of the human intestinal tract mapped across space and time
Rasa Elmentaite, Natsuhiko Kumasaka, Kenny Roberts, Aaron Fleming, Emma Dann, Hamish W. King, Vitalii Kleshchevnikov, Monika Dabrowska, Sophie Pritchard, Liam Bolt, Sara F. Vieira, Lira Mamanova, Ni Huang, Francesca Perrone, Issac Goh Kai’En, Steven N. Lisgo, Matilda Katan, Steven Leonard, Thomas R. W. Oliver, C. Elizabeth Hook, Komal Nayak, Lia S. Campos, Cecilia Domínguez Conde, Emily Stephenson, Justin Engelbert, Rachel A. Botting, Krzysztof Polanski, Stijn van Dongen, Minal Patel, Michael D. Morgan, John C. Marioni, Omer Ali Bayraktar, Kerstin B. Meyer, Xiaoling He, Roger A. Barker, Holm H. Uhlig, Krishnaa T. Mahbubani, Kourosh Saeb-Parsy, Matthias Zilbauer, Menna R. Clatworthy, Muzlifah Haniffa, Kylie R. James, Sarah A. Teichmann
Oct 01, 2021
Abstract: The cellular landscape of the human intestinal tract is dynamic throughout life, developing in utero and changing in response to functional requirements and environmental exposures. Here, to comprehensively map cell...
Cells of the human intestinal tract mapped across space and time
Rasa Elmentaite, Natsuhiko Kumasaka, Kenny Roberts, Aaron Fleming, Emma Dann, Hamish W. King, Vitalii Kleshchevnikov, Monika Dabrowska, Sophie Pritchard, Liam Bolt, Sara F. Vieira, Lira Mamanova, Ni Huang, Francesca Perrone, Issac Goh Kai’En, Steven N. Lisgo, Matilda Katan, Steven Leonard, Thomas R. W. Oliver, C. Elizabeth Hook, Komal Nayak, Lia S. Campos, Cecilia Domínguez Conde, Emily Stephenson, Justin Engelbert, Rachel A. Botting, Krzysztof Polanski, Stijn van Dongen, Minal Patel, Michael D. Morgan, John C. Marioni, Omer Ali Bayraktar, Kerstin B. Meyer, Xiaoling He, Roger A. Barker, Holm H. Uhlig, Krishnaa T. Mahbubani, Kourosh Saeb-Parsy, Matthias Zilbauer, Menna R. Clatworthy, Muzlifah Haniffa, Kylie R. James, Sarah A. Teichmann
Sep 28, 2021
Abstract: The cellular landscape of the human intestinal tract is dynamic throughout life, developing in utero and changing in response to functional requirements and environmental exposures. Here, to comprehensively map cell...
The Lantern, 2023-2024
Grace Wurzer, Naila Twyman, Owen Fazzini, Catherine Stump, Aiden Jones, Keegan McGowan, Nanditha Vinod, Olivia Cross, Tatiana Kent, Sidney Belleroche, Zach Devita-Paulson, Christopher Gerrow, Morgan Grabowski, Leyna Maio, Derek Matarazzo, Madeline O'Connor, Luke Peloquin, Ze'ev Shaheen, Hana Yolacan, Mary McNabb, Mary Lobo, Hannah Conley, Matilda Dumaine, Mairead McDermott, Abigail Prince, Livia M Nocito, Heather Reitnauer, Ashley Adam, Ryan Bernier, Erin Corcoran, Leo Cox, Julia Decamp, Izabella Entrekin, Georgia Gardner, Emily Gurganus, Amber Leech, Kelsey Lyons, Aurora McKee, Amy Smith, Miara Truog Sebouhian
Jan 01, 0001
"God," worship, and damnation in the font of my body The Men in My Life Vagabond Fishermen Unfinished Elegy Big Game Bitters On the Ferris Wheel Ruffling Feathers Haunted House Dragon in the Pond Saint Sebastian The...
Ursinus College Collegeville Pennsylvania Lantern Literary Magazine poetry fiction Creative Nonfiction Visual arts Arts and Humanities Creative Writing fiction illustration Nonfiction poetry
Published by: Ursinus College
The Lantern, 2022-2023
Kate Isabel Foley, Jenna Lozzi, Emily Gurganus, Elliot Cetinski, Juliana Valerio, Morgan Grabowski, Laura Bradley, Elliott Hannam, Catherine Stump, Tyler Ways, Alessandra Armour, Emily Bradigan, Erin Corcoran, Leo Cox, Olivia Cross, Connor Donovan, Tatiana Kent, Andrew Kmett, Olivia Negro, Miles D Noecker, Leo Quinn, Emilia Reed, Ryan Savage, Ze'ev Shaheen, Amy Smith, Vanessa Worley, Aurora McKee, Evan Chartock, Matilda Dumaine, Sharon Gearhart, Yemu Huang, Sophie K. Louis, Mairead McDermott, Jordan Ulsh, Mattie Young, Emilio de Sousa, Sarah Fales, Owen Fazzini, Georgia Gardner, Christopher Gerrow, Jonny Gherman, Keegan McGowan, David McCauley, Madeline O'Connor, Hannah Conley
Jan 01, 0001
The Genie and the Scotsman Taxi Driver Savior Complex Midnight Waltz Eulogy of Caution Don't cry over spilled milk!! I am the spider The Lamb The Witch and the Shepherd Nostalgia In the Summer I Want Light I Am (Not) ...
Ursinus College Collegeville Pennsylvania Lantern Literary Magazine poetry fiction Creative Nonfiction Visual arts Arts and Humanities Creative Writing fiction illustration Nonfiction poetry
Published by: Ursinus College
Cells of the human intestinal tract mapped across space and time.
Rasa Elmentaite, Natsuhiko Kumasaka, Kenny Roberts, Aaron Fleming, Emma Dann, Hamish W King, Vitalii Kleshchevnikov, Monika Dabrowska, Sophie Pritchard, Liam Bolt, Sara F Vieira, Lira Mamanova, Ni Huang, Francesca Perrone, Issac Goh Kai'En, Steven N Lisgo, Matilda Katan, Steven Leonard, Thomas RW Oliver, C Elizabeth Hook, Komal Nayak, Lia S Campos, Cecilia Domínguez Conde, Emily Stephenson, Justin Engelbert, Rachel A Botting, Krzysztof Polanski, Stijn van Dongen, Minal Patel, Michael D Morgan, John C Marioni, Omer Ali Bayraktar, Kerstin B Meyer, Xiaoling He, Roger A Barker, Holm H Uhlig, Krishnaa T Mahbubani, Kourosh Saeb-Parsy, Matthias Zilbauer, Menna R Clatworthy, Muzlifah Haniffa, Kylie R James, Sarah A Teichmann
Sep 07, 2021
The cellular landscape of the human intestinal tract is dynamic throughout life, developing in utero and changing in response to functional requirements and environmental exposures. Here, to comprehensively map cell lineages, we...
Deep brain stimulation for refractory obsessive-compulsive disorder (OCD)
Hemmings Wu, Marwan Hariz, Veerle Visser-Vandewalle, Ludvic Zrinzo, Volker A Coenen, Sameer A Sheth, Chris Bervoets, Matilda Naesström, Patric Blomstedt, Terry Coyne, Clement Hamani, Konstantin Slavin, Joachim K Krauss, Kai G Kahl, Takaomi Taira, Chencheng Zhang, Bomin Sun, Hiroki Toda, Thomas Schlaepfer, Jin Woo Chang, Jean Régis, Rick Schuurman, Michael Schulder, Paresh Doshi, Philip Mosley, Anujan Poologaindran, Gabriel Lázaro-Muñoz, Joshua Pepper, Gaston Schechtmann, Anders Fytagoridis, Daniel Huys, Antonio Gonçalves-Ferreira, Pierre-François D'Haese, Joseph Neimat, Giovanni Broggi, Osvaldo Vilela-Filho, Jürgen Voges, Ahmed Alkhani, Takeshi Nakajima, Raphaelle Richieri, Diana Djurfeldt, Philippe Fontaine, Roberto Martinez-Alvarez, Yasushi Okamura, Jennifer Chandler, Katsushige Watanabe, Juan A Barcia, Blanca Reneses, Andres Lozano, Loes Gabriëls, Antonio De Salles, Casey H Halpern, Keith Matthews, Joseph J Fins, Bart Nuttin
Nov 09, 2020
A consensus has yet to emerge whether deep brain stimulation (DBS) for treatment-refractory obsessive-compulsive disorder (OCD) can be considered an established therapy. In 2014, the World Society for Stereotactic and Functional...
Cells of the human intestinal tract mapped across space and time.
Rasa Elmentaite, Natsuhiko Kumasaka, Kenny Roberts, Aaron Fleming, Emma Dann, Hamish W King, Vitalii Kleshchevnikov, Monika Dabrowska, Sophie Pritchard, Liam Bolt, Sara F Vieira, Lira Mamanova, Ni Huang, Francesca Perrone, Issac Goh Kai'En, Steven N Lisgo, Matilda Katan, Steven Leonard, Thomas R W Oliver, C Elizabeth Hook, Komal Nayak, Lia S Campos, Cecilia Domínguez Conde, Emily Stephenson, Justin Engelbert, Rachel A Botting, Krzysztof Polanski, Stijn van Dongen, Minal Patel, Michael D Morgan, John C Marioni, Omer Ali Bayraktar, Kerstin B Meyer, Xiaoling He, Roger A Barker, Holm H Uhlig, Krishnaa T Mahbubani, Kourosh Saeb-Parsy, Matthias Zilbauer, Menna R Clatworthy, Muzlifah Haniffa, Kylie R James, Sarah A Teichmann
Oct 10, 2021
Intestines Enteric Nervous System Lymph Nodes Epithelial Cells Fetus Animals Mice Inbred C57BL Humans Mice Crohn Disease Receptors IgG Signal Transduction aging Organogenesis Time Factors Adult Child HEALTH Female Spatio-Temporal Analysis Datasets as Topic
Published by: Nature
Cells of the human intestinal tract mapped across space and time
Rasa Elmentaite, Natsuhiko Kumasaka, Kenny Roberts, Aaron Fleming, Emma Dann, Hamish W. King, Vitalii Kleshchevnikov, Monika Dabrowska, Sophie Pritchard, Liam Bolt, Sara F. Vieira, Lira Mamanova, Ni Huang, Francesca Perrone, Issac Goh Kai’En, Steven N. Lisgo, Matilda Katan, Steven Leonard, Thomas R. W. Oliver, C. Elizabeth Hook, Komal Nayak, Lia S. Campos, Cecilia Domínguez Conde, Emily Stephenson, Justin Engelbert, Rachel A. Botting, Krzysztof Polanski, Stijn van Dongen, Minal Patel, Michael D. Morgan, John C. Marioni, Omer Ali Bayraktar, Kerstin B. Meyer, Xiaoling He, Roger A. Barker, Holm H. Uhlig, Krishnaa T. Mahbubani, Kourosh Saeb-Parsy, Matthias Zilbauer, Menna R. Clatworthy, Muzlifah Haniffa, Kylie R. James, Sarah A. Teichmann
Sep 09, 2021
Abstract: The cellular landscape of the human intestinal tract is dynamic throughout life, developing in utero and changing in response to functional requirements and environmental exposures. Here, to comprehensively map cell...
Predicting and elucidating the etiology of fatty liver disease
Naeimeh Atabaki-Pasdar, Mattias Ohlsson, Ana Viñuela, Francesca Frau, Hugo Pomares-Millan, Mark Haid, Angus G Jones, E Louise Thomas, Robert W Koivula, Azra Kurbasic, Pascal M Mutie, Hugo Fitipaldi, Juan Fernandez, Adem Y Dawed, Giuseppe N Giordano, Ian M Forgie, Timothy J McDonald, Femke Rutters, Henna Cederberg, Elizaveta Chabanova, Matilda Dale, Federico De Masi, Cecilia Engel Thomas, Kristine H Allin, Tue H Hansen, Alison Heggie, Mun-Gwan Hong, Petra JM Elders, Gwen Kennedy, Tarja Kokkola, Helle Krogh Pedersen, Anubha Mahajan, Donna McEvoy, Francois Pattou, Violeta Raverdy, Ragna S Häussler, Sapna Sharma, Henrik S Thomsen, Jagadish Vangipurapu, Henrik Vestergaard, Leen M 't Hart, Jerzy Adamski, Petra B Musholt, Soren Brage, Søren Brunak, Emmanouil Dermitzakis, Gary Frost, Torben Hansen, Markku Laakso, Oluf Pedersen, Martin Ridderstråle, Hartmut Ruetten, Andrew T Hattersley, Mark Walker, Joline WJ Beulens, Andrea Mari, Jochen M Schwenk, Ramneek Gupta, Mark I McCarthy, Ewan R Pearson, Jimmy D Bell, Imre Pavo, Paul W Franks
Jun 09, 2020
BACKGROUND: Non-alcoholic fatty liver disease (NAFLD) is highly prevalent and causes serious health complications in individuals with and without type 2 diabetes (T2D). Early diagnosis of NAFLD is important, as this can help...
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