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Water Insecurity in Indigenous Canada
Water insecurity in Northern Indigenous communities in Canada is pervasive and complex with multiple dimensions and impacts. Yet the relevant literature is sparse, especially for Labrador. Our case study aimed to understand the...
Human pluripotent stem cells recurrently acquire and expand dominant negative P53 mutations.
Florian T Merkle, Sulagna Ghosh, Nolan Kamitaki, Jana Mitchell, Yishai Avior, Curtis Mello, Seva Kashin, Shila Mekhoubad, Dusko Ilic, Maura Charlton, Genevieve Saphier, Robert E Handsaker, Giulio Genovese, Shiran Bar, Nissim Benvenisty, Steven A McCarroll, Kevin Eggan
May 01, 2017
Alleles Cell Count Cell Differentiation Cell Division Cell Line DNA DNA Mutational Analysis Exome Genes Dominant Genes p53 Human Embryonic Stem Cells Humans Induced Pluripotent Stem Cells Loss of Heterozygosity Mosaicism Mutation Neoplasms Protein Domains selection Genetic Tumor Suppressor Protein p53
Is a matrix exponential specification suitable for the modeling of spatial correlation structures?
This paper investigates the adequacy of the matrix exponential spatial specifications (MESS) as an alternative to the widely used spatial autoregressive models (SAR). To provide as complete a picture as possible, we extend the...
Genetic disorders of thyroid development, hormone biosynthesis and signalling.
Carla Moran, Nadia Schoenmakers, W Edward Visser, Erik Schoenmakers, Maura Agostini, Krishna Chatterjee
Sep 06, 2022
Will MRI of gastrointestinal function parallel the clinical success of cine cardiac MRI?
Water Insecurity in Indigenous Canada
Water insecurity in Northern Indigenous communities in Canada is pervasive and complex with multiple dimensions and impacts. Yet the relevant literature is sparse, especially for Labrador. Our case study aimed to understand the...
Shoulder and Elbow Injury Prevention in Baseball Pitchers
Taylor Charlton
Jan 01, 0001
Shoulder and elbow injuries are extremely common in baseball pitchers due to overuse and extreme stress. To assess the risk factors for these injuries, adolescents were chosen to complete testing on strength and range of motion....
Published by: Winthrop University
Variant-specific vulnerability in metabolic connectivity and resting-state networks in behavioural variant of frontotemporal dementia.
Maura Malpetti, Giulia Carli, Arianna Sala, Chiara Cerami, Alessandra Marcone, Sandro Iannaccone, Giuseppe Magnani, Daniela Perani
Jul 10, 2020
Brain connectivity measures represent candidate biomarkers of neuronal dysfunction in neurodegenerative diseases. Previous findings suggest that the behavioural variant of frontotemporal dementia (bvFTD) and its variants (i.e....
Behavioural variant of frontotemporal dementia Brain metabolic connectivity Fluorine-18-flourodeoxiglucose positron emission tomography Aged Attention Brain Brain Mapping Cognition Connectome Female frontotemporal dementia Humans Male Memory Middle Aged Nerve Net Neuropsychological Tests Positron-Emission Tomography
Looking beneath the surface
Whilst initial anatomical studies of frontotemporal dementia focussed on cortical involvement, the relevance of subcortical structures to the pathophysiology of frontotemporal dementia has been increasingly recognized over...
The neurological and ophthalmological manifestations of SPG4-related hereditary spastic paraplegia.
Grant Guthrie, Gerald Pfeffer, Maura Bailie, Karen Bradshaw, Andrew C Browning, Rita Horvath, Patrick F Chinnery, Patrick Yu-Wai-Man
Mar 07, 2019
Statins during pregnancy
The aim of this study was to determine if there are any differences between the types of pregnancy loss experienced by women who have been prescribed a statin just before or early in pregnancy compared with those who have...
Influence of Photoplethysmogram Signal Quality on Pulse Arrival Time during Polysomnography.
Intervals of low-quality photoplethysmogram (PPG) signals might lead to significant inaccuracies in estimation of pulse arrival time (PAT) during polysomnography (PSG) studies. While PSG is considered to be a "gold standard"...
Safety of fluticasone propionate prescribed for asthma during pregnancy
Background: Asthma is commonly treated during pregnancy, yet data on the safety of asthma medicines used during pregnancy are sparse. Objective: The objective of this study was to evaluate the safety of the inhaled...
Influence of Photoplethysmogram Signal Quality on Pulse Arrival Time during Polysomnography.
Statins during pregnancy
The aim of this study was to determine if there are any differences between the types of pregnancy loss experienced by women who have been prescribed a statin just before or early in pregnancy compared with those who have...
Acquiring Wearable Photoplethysmography Data in Daily Life
The photoplethysmogram (PPG) signal is widely measured by smart watches and fitness bands for heart rate monitoring. New applications of the PPG are also emerging, such as to detect irregular heart rhythms, track infectious...
Peak Width of Skeletonized Mean Diffusivity as a Marker of Diffuse Cerebrovascular Damage
Audrey Low, Elijah Mak, James D. Stefaniak, Maura Malpetti, Nicolas Nicastro, George Savulich, Leonidas Chouliaras, Hugh S. Markus, James B. Rowe, John T. O’Brien
Apr 02, 2020
Background: The peak width of skeletonized mean diffusivity (PSMD) has been proposed as a fully automated imaging marker of relevance to cerebral small vessel disease (SVD). We assessed PSMD in relation to conventional SVD...
Brain Regional Identity and Cell Type Specificity Landscape of Human Cortical Organoid Models.
Manuela Magni, Beatrice Bossi, Paola Conforti, Maura Galimberti, Fabio Dezi, Tiziana Lischetti, Xiaoling He, Roger A Barker, Chiara Zuccato, Ira Espuny-Camacho, Elena Cattaneo
Nov 15, 2022
The default mode network is disrupted in Parkinson's disease with visual hallucinations.
Nailin Yao, Richard Shek-Kwan Chang, Charlton Cheung, Shirley Pang, Kui Kai Lau, John Suckling, James B Rowe, Kevin Yu, Henry Ka-Fung Mak, Siew-Eng Chua, Shu Leong Ho, Grainne M McAlonan
Feb 04, 2016
Living in state housing
This special issue focuses on state housing in Africa as a space of living. This topic is prompted by two factors: firstly, an empirical recognition that increasing numbers of African citizens are living in state-supported...
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