Mechanism of efficient double-strand break repair by a long non-coding RNA.
Roopa Thapar,
Jing L Wang,
Michal Hammel,
Ruiqiong Ye,
Ke Liang,
Chengcao Sun,
Ales Hnizda,
Shikang Liang,
Su S Maw,
Linda Lee,
Heather Villarreal,
Isaac Forrester,
Shujuan Fang,
Miaw-Sheue Tsai,
Tom L Blundell,
Anthony J Davis,
Chunru Lin,
Susan P Lees-Miller,
Terence R Strick,
John A Tainer
Nov 30, 2020
Mechanistic studies in DNA repair have focused on roles of multi-protein DNA complexes, so how long non-coding RNAs (lncRNAs) regulate DNA repair is less well understood. Yet, lncRNA LINP1 is over-expressed in multiple cancers...