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Results: 1579
Best practices for multi-ancestry, meta-analytic transcriptome-wide association studies
Arjun Bhattacharya, Jibril B Hirbo, Dan Zhou, Wei Zhou, Jie Zheng, Masahiro Kanai, Global Biobank Meta-analysis Initiative, Bogdan Pasaniuc, Eric R Gamazon, Nancy J Cox
Dec 08, 2022
The Global Biobank Meta-analysis Initiative (GBMI), through its diversity, provides a valuable opportunity to study population-wide and ancestry-specific genetic associations. However, with multiple ascertainment strategies and...
Meta-QSAR
Ivan Olier, Noureddin Sadawi, G Richard Bickerton, Joaquin Vanschoren, Crina Grosan, Larisa Soldatova, Ross D King
Jul 07, 2020
We investigate the learning of quantitative structure activity relationships (QSARs) as a case-study of meta-learning. This application area is of the highest societal importance, as it is a key step in the development of new...
Deriving percentage study weights in multi-parameter meta-analysis models
Many meta-analysis models contain multiple parameters, for example due to multiple outcomes, multiple treatments or multiple regression coefficients. In particular, meta-regression models may contain multiple study-level...
Meta-analysis
Building a foundation of marketing theory requires developing effective ways to aggregate research results. Meta-analyses that accumulate knowledge within a research domain is an important means for summarizing research...
Meta-analysis
Building a foundation of marketing theory requires developing effective ways to aggregate research results. Meta-analyses that accumulate knowledge within a research domain is an important means for summarizing research...
Autism and the right to education in the EU
Robin van Kessel, Sebastian Walsh, Amber N. V. Ruigrok, Rosemary Holt, Anneli Yliherva, Eija Kärnä, Irma Moilanen, Eva Hjörne, Shruti Taneja Johansson, Diana Schendel, Lennart Pedersen, Meta Jørgensen, Carol Brayne, Simon Baron-Cohen, Andres Roman-Urrestarazu
Dec 10, 2020
Abstract: Introduction: The universal right to education for people with disabilities has been highlighted by the Universal Declaration on Human Rights and the Convention on the Rights of Persons with Disabilities. In this...
Dynamic meta-analysis
Gorm E Shackelford, Philip A Martin, Amelia SC Hood, Alec P Christie, Elena Kulinskaya, William J Sutherland
Feb 25, 2021
BACKGROUND: Meta-analysis is often used to make generalisations across all available evidence at the global scale. But how can these global generalisations be used for evidence-based decision making at the local scale, if the...
Genome-Wide Meta-Analysis Identifies Variants in DSCAM and PDLIM3 That Correlate with Efficacy Outcomes in Metastatic Renal Cell Carcinoma Patients Treated with Sunitinib.
Meta HM Diekstra, Jesse J Swen, Loes FM van der Zanden, Sita H Vermeulen, Epie Boven, Ron HJ Mathijssen, Koya Fukunaga, Taisei Mushiroda, Fumiya Hongo, Egbert Oosterwijk, Anne Cambon-Thomsen, Daniel Castellano, Achim Fritsch, Jesus Garcia Donas, Cristina Rodriguez-Antona, Rob Ruijtenbeek, Marius T Radu, Tim Eisen, Kerstin Junker, Max Roessler, Ulrich Jaehde, Tsuneharu Miki, Stefan Böhringer, Michiaki Kubo, Lambertus ALM Kiemeney, Henk-Jan Guchelaar
Jul 24, 2022
Individual response to sunitinib in metastatic renal cell carcinoma (mRCC) patients is highly variable. Earlier, sunitinib outcome was related to single nucleotide polymorphisms (SNPs) in CYP3A5 and ABCB1. Our aim is to provide...
Autism and the right to education in the EU
Robin van Kessel, Sebastian Walsh, Amber N V Ruigrok, Rosemary Holt, Anneli Yliherva, Eija Kärnä, Irma Moilanen, Eva Hjörne, Shruti Taneja Johansson, Diana Schendel, Lennart Pedersen, Meta Jørgensen, Carol Brayne, Simon Baron-Cohen, Andres Roman-Urrestarazu
Jan 29, 2020
Introduction:The universal right to education for people with disabilities has been highlighted by the Universal Declaration on Human Rights and the Convention on the Rights of Persons with Disabilities. In this paper, we mapped...
Sociodemographic inequities associated with participation in leisure-time physical activity in sub-Saharan Africa
Anna Louise Barr, Uttara Partap, Elizabeth H. Young, Kokou Agoudavi, Naby Balde, Gibson B. Kagaruki, Mary T. Mayige, Benjamin Longo-Mbenza, Gerald Mutungi, Omar Mwalim, Chea S. Wesseh, Silver K. Bahendeka, David Guwatudde, Jutta M. Adelin Jørgensen, Pascal Bovet, Ayesha A. Motala, Manjinder S. Sandhu
Jun 15, 2020
Abstract: Background: Leisure-time physical activity (LTPA) is an important contributor to total physical activity and the focus of many interventions promoting activity in high-income populations. Little is known about LTPA in...
Sociodemographic inequities associated with participation in leisure-time physical activity in sub-Saharan Africa
Anna Louise Barr, Uttara Partap, Elizabeth H. Young, Kokou Agoudavi, Naby Balde, Gibson B. Kagaruki, Mary T. Mayige, Benjamin Longo-Mbenza, Gerald Mutungi, Omar Mwalim, Chea S. Wesseh, Silver K. Bahendeka, David Guwatudde, Jutta M. Adelin Jørgensen, Pascal Bovet, Ayesha A. Motala, Manjinder S. Sandhu
Jun 15, 2021
Abstract: Background: Leisure-time physical activity (LTPA) is an important contributor to total physical activity and the focus of many interventions promoting activity in high-income populations. Little is known about LTPA in...
Implementing informative priors for heterogeneity in meta-analysis using meta-regression and pseudo data.
Kirsty M Rhodes, Rebecca M Turner, Ian R White, Dan Jackson, David J Spiegelhalter, Julian PT Higgins
Jun 18, 2018
Many meta-analyses combine results from only a small number of studies, a situation in which the between-study variance is imprecisely estimated when standard methods are applied. Bayesian meta-analysis allows incorporation of...
Sociodemographic inequities associated with participation in leisure-time physical activity in sub-Saharan Africa
Anna Louise Barr, Uttara Partap, Elizabeth H Young, Kokou Agoudavi, Naby Balde, Gibson B Kagaruki, Mary T Mayige, Benjamin Longo-Mbenza, Gerald Mutungi, Omar Mwalim, Chea S Wesseh, Silver K Bahendeka, David Guwatudde, Jutta M Adelin Jørgensen, Pascal Bovet, Ayesha A Motala, Manjinder S Sandhu
Aug 19, 2020
BACKGROUND: Leisure-time physical activity (LTPA) is an important contributor to total physical activity and the focus of many interventions promoting activity in high-income populations. Little is known about LTPA in...
Active travel equity Global physical activity questionnaire Leisure-time physical activity Mechanisation Occupational physical activity physical activity Recreation Sub-Saharan Africa urbanisation Adult Africa South of the Sahara Aged Aged 80 and over Exercise Female Health Promotion Humans Leisure Activities Male Middle Aged Odds Ratio Socioeconomic Factors Surveys and Questionnaires Young Adult
Power analysis for random-effects meta-analysis
One of the reasons for the popularity of meta-analysis is the notion that these analyses will possess more power to detect effects than individual studies. This is inevitably the case under a fixed-effect model. However, the...
Nonlinear superchiral meta-surfaces
V. K. Valev, J. J. Baumberg, B. De Clercq, N. Braz, X. Zheng, E. J. Osley, S. Vandendriessche, M. Hojeij, C. Blejean, J. Mertens, C. G. Biris, V. Volskiy, M. Ameloot, Y. Ekinci, G. A E Vandenbosch, P. A. Warburton, V. V. Moshchalkov, N. C. Panoiu, T. Verbiest
Jun 25, 2014
Circularly polarized light is incident on a nanostructured chiral meta-surface. In the nanostructured unit cells whose chirality matches that of light, superchiral light is forming and strong optical second harmonic...
Nonlinear superchiral meta-surfaces
V. K. Valev, J. J. Baumberg, B. De Clercq, N. Braz, X. Zheng, E. J. Osley, S. Vandendriessche, M. Hojeij, C. Blejean, J. Mertens, C. G. Biris, V. Volskiy, M. Ameloot, Y. Ekinci, G. A E Vandenbosch, P. A. Warburton, V. V. Moshchalkov, N. C. Panoiu, T. Verbiest
Jun 25, 2014
Circularly polarized light is incident on a nanostructured chiral meta-surface. In the nanostructured unit cells whose chirality matches that of light, superchiral light is forming and strong optical second harmonic...
Ruthenium-catalyzed meta sulfonation of 2-phenylpyridines
Ourida Saidi, J Marafie, Araminta E W Ledger, Po Man Liu, Mary F Mahon, Gabriele Kociok-Kohn, Michael K Whittlesey, Christopher G Frost
Dec 07, 2011
A selective catalytic meta sulfonation of 2-phenylpyridines was found to occur in the presence of (arene)ruthenium(II) complexes upon reaction with sulfonyl chlorides. The 2-pyridyl group facilitates the formation of a stable...
Nonlinear superchiral meta-surfaces
VK Valev, JJ Baumberg, B De Clercq, N Braz, X Zheng, EJ Osley, S Vandendriessche, M Hojeij, C Blejean, J Mertens, CG Biris, V Volskiy, M Ameloot, Y Ekinci, GAE Vandenbosch, PA Warburton, VV Moshchalkov, NC Panoiu, T Verbiest
Sep 08, 2018
Circularly polarized light is incident on a nanostructured chiral meta-surface. In the nanostructured unit cells whose chirality matches that of light, superchiral light is forming and strong optical second harmonic generation...
Ruthenium-catalyzed meta sulfonation of 2-phenylpyridines
Ourida Saidi, J Marafie, Araminta E W Ledger, Po Man Liu, Mary F Mahon, Gabriele Kociok-Kohn, Michael K Whittlesey, Christopher G Frost
Dec 07, 2011
A selective catalytic meta sulfonation of 2-phenylpyridines was found to occur in the presence of (arene)ruthenium(II) complexes upon reaction with sulfonyl chlorides. The 2-pyridyl group facilitates the formation of a stable...
A Comparative Study of Meta-Heuristic and Conventional Search in Optimization of Multi-Dimensional Feature Selection
Algorithmic – based search approach is ineffective at addressing the problem of multi-dimensional feature selection for document categorization. This study proposes the use of meta heuristic based search approach for optimal...
Published by: IGI Global Scientific Publishing
Cerebellar atrophy in neurodegeneration-a meta-analysis.
Helena M Gellersen, Christine C Guo, Claire O'Callaghan, Rachel H Tan, Saber Sami, Michael Hornberger
Dec 01, 2017
INTRODUCTION: The cerebellum has strong cortical and subcortical connectivity, but is rarely taken into account for clinical diagnosis in many neurodegenerative conditions, particularly in the absence of clinical ataxia. The...
Adjusting trial results for biases in meta-analysis
KM Rhodes, J Savović, R Elbers, HE Jones, JPT Higgins, JAC Sterne, NJ Welton, RM Turner
Jan 27, 2020
Flaws in the conduct of randomized trials can lead to biased estimation of the intervention effect. Methods for adjustment of within-trial biases in meta-analysis include the use of empirical evidence from an external collection...
Meta-Parametric Design
Parametric modelling software often maintains an explicit history of design development in the form of a graph. However, as the graph increases in complexity it quickly becomes inflexible and unsuitable for exploring a wide...
Predicting rice phenotypes with meta and multi-target learning
Abstract: The features in some machine learning datasets can naturally be divided into groups. This is the case with genomic data, where features can be grouped by chromosome. In many applications it is common for these...
Meta-analysis of genome-wide association studies in African Americans provides insights into the genetic architecture of type 2 diabetes.
Maggie CY Ng, Daniel Shriner, Brian H Chen, Jiang Li, Wei-Min Chen, Xiuqing Guo, Jiankang Liu, Suzette J Bielinski, Lisa R Yanek, Michael A Nalls, Mary E Comeau, Laura J Rasmussen-Torvik, Richard A Jensen, Daniel S Evans, Yan V Sun, Ping An, Sanjay R Patel, Yingchang Lu, Jirong Long, Loren L Armstrong, Lynne Wagenknecht, Lingyao Yang, Beverly M Snively, Nicholette D Palmer, Poorva Mudgal, Carl D Langefeld, Keith L Keene, Barry I Freedman, Josyf C Mychaleckyj, Uma Nayak, Leslie J Raffel, Mark O Goodarzi, Y-D Ida Chen, Herman A Taylor, Adolfo Correa, Mario Sims, David Couper, James S Pankow, Eric Boerwinkle, Adebowale Adeyemo, Ayo Doumatey, Guanjie Chen, Rasika A Mathias, Dhananjay Vaidya, Andrew B Singleton, Alan B Zonderman, Robert P Igo, John R Sedor, FIND Consortium, Edmond K Kabagambe, David S Siscovick, Barbara McKnight, Kenneth Rice, Yongmei Liu, Wen-Chi Hsueh, Wei Zhao, Lawrence F Bielak, Aldi Kraja, Michael A Province, Erwin P Bottinger, Omri Gottesman, Qiuyin Cai, Wei Zheng, William J Blot, William L Lowe, Jennifer A Pacheco, Dana C Crawford, eMERGE Consortium, DIAGRAM Consortium, Elin Grundberg, MuTHER Consortium, Stephen S Rich, M Geoffrey Hayes, Xiao-Ou Shu, Ruth JF Loos, Ingrid B Borecki, Patricia A Peyser, Steven R Cummings, Bruce M Psaty, Myriam Fornage, Sudha K Iyengar, Michele K Evans, Diane M Becker, WH Linda Kao, James G Wilson, Jerome I Rotter, Michèle M Sale, Simin Liu, Charles N Rotimi, Donald W Bowden, MEta-analysis of type 2 DIabetes in African Americans Consortium
May 08, 2018
Type 2 diabetes (T2D) is more prevalent in African Americans than in Europeans. However, little is known about the genetic risk in African Americans despite the recent identification of more than 70 T2D loci primarily by...
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