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Calcium imaging analysis - how far have we come?
Techniques for calcium imaging were first demonstrated in the mid-1970s, whilst tools to analyse these markers of cellular activity are still being developed and improved today. For image analysis, custom tools were developed...
classification Neural Networks Quantification denoising calcium imaging Machine Learning motion correction
Published by: F1000Research
Calcium imaging analysis - how far have we come?
Techniques for calcium imaging were first demonstrated in the mid-1970s, whilst tools to analyse these markers of cellular activity are still being developed and improved today. For image analysis, custom tools were developed...
Neurobehavioural sequelae of social deprivation in rodents revisited
TW Robbins
Apr 11, 2018
The significance of investigating effects of deprivation of social experience in rodents is reviewed in the context of the review by Robbins et al. (1996) in the Journal of Psychopharmacology (10: 39-47). The early development...
ADHD Social Isolation animal model Cognition Dopamine Hippocampus hyperactivity Prefrontal Cortex prepulse inhibition Schizophrenia Serotonin Striatum Animals Attention Deficit Disorder with Hyperactivity Behavior Animal Cognition Dopamine Hippocampus Humans Mental Disorders motivation Rodentia Schizophrenia Serotonin Social Isolation
Microelectrode Arrays for Simultaneous Electrophysiology and Advanced Optical Microscopy
Sagnik Middya, Vincenzo F. Curto, Ana Fernández‐Villegas, Miranda Robbins, Johannes Gurke, Emma J. M. Moonen, Gabriele S. Kaminski Schierle, George G. Malliaras
May 11, 2021
RESEARCH ARTICLE RESEARCH ARTICLES bioelectronics conducting polymers Electrophysiology optical microscopy
Published by: Advanced Science
Guidelines for Data Collection to Measure SDG 4.7.4 and 4.7.5
In an effort to promote robust and comparable measurements of SDG 4 in this Decade of Action as nations strive to meet education targets, the UIS has spearheaded a methodological program on learning outcomes. Drawing from the...
Published by: UNESCO Institute for Statistics
Guidelines for Data Collection to Measure SDG 4.7.4 and 4.7.5
In an effort to promote robust and comparable measurements of SDG 4 in this Decade of Action as nations strive to meet education targets, the UIS has spearheaded a methodological program on learning outcomes. Drawing from the...
Published by: UNESCO Institute for Statistics
Biofunctionalised bacterial cellulose scaffold supports the patterning and expansion of human embryonic stem cell-derived dopaminergic progenitor cells.
Miranda Robbins, Venkat Pisupati, Roberta Azzarelli, Samer I Nehme, Roger A Barker, Ljiljana Fruk, Gabriele S Kaminski Schierle
Jan 07, 2022
BACKGROUND: Stem cell-based therapies for neurodegenerative diseases like Parkinson's disease are a promising approach in regenerative medicine and are now moving towards early stage clinical trials. However, a number of...
Early identification of patients with Chagas disease at risk of developing cardiomyopathy using 2-D speckle tracking strain
Sithu Win, Monica Miranda-Schaeubinger, Ronald Gustavo Durán Saucedo, Paula Carballo Jimenez, Jorge Flores, Brandon Mercado-Saavedra, Lola Camila Telleria, Anne Raafs, Manuela Verastegui, Caryn Bern, Freddy Tinajeros, Stephane Heymans, Rachel Marcus, Robert H Gilman, Monica Mukherjee, Chagas Working Group
Jul 02, 2022
The Democracy to Come? An Enquiry Into the Vision of Blockchain-Powered E-Voting Start-Ups
This research sets out to analyze the message promoted by start-up enterprises that apply blockchain technologies for the purpose of e-voting [blockchain-powered e-voting (BPE)], and their perceived effects of this...
Miranda Imperial
Apr 23, 2021
Fossils Collected This Summer Will Be Subject of Tests
Winthrop University
Jan 01, 0001
Boyer and two environmental science majors, Tim Swartz and Ty Robbins, took a 13-day trip in June to Utah and Nevada to collect rock samples on federal lands believed to have been the site of mass extinctions. The Winthrop study...
Published by: Winthrop University
Frontotemporal dementia caused by CHMP2B mutation is characterised by neuronal lysosomal storage pathology.
Emma L Clayton, Sarah Mizielinska, James R Edgar, Troels Tolstrup Nielsen, Sarah Marshall, Frances E Norona, Miranda Robbins, Hana Damirji, Ida E Holm, Peter Johannsen, Jørgen E Nielsen, Emmanuel A Asante, John Collinge, FReJA consortium, Adrian M Isaacs
Feb 11, 2019
Mutations in the charged multivesicular body protein 2B (CHMP2B) cause frontotemporal dementia (FTD). We report that mice which express FTD-causative mutant CHMP2B at physiological levels develop a novel lysosomal storage...
CHMP2B ESCRT FTD lysosomal storage disorder lysosome Aged Aged 80 and over Animals Brain Disease Models Animal Disease Progression Endosomal Sorting Complexes Required for Transport Female frontotemporal dementia Humans Lysosomes Male Mice Transgenic Microglia Middle Aged Mutation Nerve Tissue Proteins Neurons Protein Multimerization
Poverty on a College Campus
Poverty is a reality for many individuals and families - including the college student. Unless you have experienced it yourself, it is difficult to understand. Join us for an interactive discussion on poverty: the complex and...
Published by: Winthrop University
“Unusual Greenness”
Miranda Griffin
Nov 05, 2018
The books reviewed in this essay bring together various strands of thought that center on the material and the nonhuman in the Middle Ages: the things and landscapes that furnish, ground, and transmit medieval texts, but that...
Capabilities, resources, learning and innovation
The dominant approach in economics, often referred to as neoclassical economics, gradually acquired its leading status in the years following the publication of Lionel Robbins’s (1932) famous essay on the nature and significance...
Protocol for Extraction and Electron Microscopy Visualization of Lipids in Viburnum tinus Fruit Using Cryo-Ultramicrotomy.
We recently reported that Viburnum tinus fruit generates its metallic blue color using globular lipid inclusions embedded in its epicarpal cell walls. This protocol describes steps to visualize the lipidic nature of the...
Gait pattern alterations during walking, texting and walking and texting during cognitively distractive tasks while negotiating common pedestrian obstacles
Objectives Mobile phone texting is a common daily occurrence with a paucity of research examining corresponding gait characteristics. To date, most studies have participants walk in a straight line vs. overcoming barriers and...
Two Donations to Environmental Programs Expand Opportunities for Students
Winthrop University
Jan 01, 0001
Ty Robbins, a senior environmental sciences major from Clemson, South Carolina, and Allyssa Calderhead, a senior environmental studies major living in Fort Mill, are the first two Dalton Scholarship recipients. In other...
Published by: Winthrop University
Feedback from Outcome Measures and Treatment Effectiveness, Treatment Efficiency, and Collaborative Practice
Due to recent increases in the use of feedback from outcome measures in mental health settings, we systematically reviewed evidence regarding the impact of feedback from outcome measures on treatment effectiveness, treatment...
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