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A system for the expression and release of heterologous proteins from the core of Bacillus subtilis spores.
Metal-Bound Methisazone; Novel Drugs Targeting Prophylaxis and Treatment of SARS-CoV-2, a Molecular Docking Study.
Ahmed Abdelaal Ahmed Mahmoud M Alkhatip, Michail Georgakis, Lucio R Montero Valenzuela, Mohamed Hamza, Ehab Farag, Jaqui Hodgkinson, Hisham Hosny, Ahmed M Kamal, Mohamed Wagih, Amr Naguib, Hany Yassin, Haytham Algameel, Mohamed Elayashy, Mohamed Abdelhaq, Mohamed I Younis, Hassan Mohamed, Mohammed Abdulshafi, Mohamed A Elramely
Mar 16, 2021
SARS-CoV-2 currently lacks effective first-line drug treatment. We present promising data from in silico docking studies of new Methisazone compounds (modified with calcium, Ca; iron, Fe; magnesium, Mg; manganese, Mn; or zinc...
covid-19 SARS-CoV-2 Molecular docking prophylaxis Treatment Antiviral Agents Calcium Coronavirus 3C Proteases Coronavirus Papain-Like Proteases Coronavirus RNA-Dependent RNA Polymerase Drug Design Humans Iron Magnesium manganese Metals Methisazone Models Molecular Molecular Docking Simulation Molecular Dynamics Simulation Protein Binding SARS-CoV-2 Spike Glycoprotein Coronavirus Zinc COVID-19 Drug Treatment
The orthopaedic experience of COVID-19
This literature review aims to provide an account of the changes to orthopaedics in the era of COVID-19. Herein, the authors explored the use of telemedicine in orthopaedics as well as changes in surgical protocols, screening...
Experimental and Analytical Investigation of the Response of a Triboelectric Generator Under Different Operating Conditions
This article provides experimental and theoretical studies on the effect of operating conditions on the output response of triboelectric generators. The influence of specific parameters is examined in detail, including...
Genotoxic and Anatomical Deteriorations Associated with Potentially Toxic Elements Accumulation in Water Hyacinth Grown in Drainage Water Resources
Potentially toxic elements (PTEs)-induced genotoxicity on aquatic plants is still an open question. Herein, a single clone from a population of water hyacinth covering a large distribution area of Nile River (freshwater)...
Farahat S Moghanm, Antar El-Banna, Mohamed A El-Esawi, Mohamed M Abdel-Daim, Ahmed Mosa, Khaled AA Abdelaal
Mar 11, 2020
A hybrid profit and loss sharing model using interest free-debt and equity financing
In this paper two models are contrasted whereby a corporation is seeking to finance the purchase of a merchandise from a supplier through a profit and loss sharing contract. The first mode consist of financing the purchase...
Experimental and Analytical Investigation of the Response of a Triboelectric Generator Under Different Operating Conditions
This article provides experimental and theoretical studies on the effect of operating conditions on the output response of triboelectric generators. The influence of specific parameters is examined in detail, including...
Development of Novel Isatin-Tethered Quinolines as Anti-Tubercular Agents against Multi and Extensively Drug-Resistant Mycobacterium tuberculosis.
Mohamed A Abdelrahman, Hadia Almahli, Tarfah Al-Warhi, Taghreed A Majrashi, Marwa M Abdel-Aziz, Wagdy M Eldehna, Mohamed A Said
Jan 26, 2023
We describe the design and synthesis of two isatin-tethered quinolines series (Q6a-h and Q8a-h), in connection with our research interest in developing novel isatin-bearing anti-tubercular candidates. In a previous study, a...
High-flow nasal oxygen vs. standard oxygen therapy for patients undergoing transcatheter aortic valve replacement with conscious sedation
S Scheuermann, A Tan, P Govender, M Mckie, J Pack, G Martinez, F Falter, S George, A A. Klein
Apr 14, 2023
Circulating Monocyte Chemoattractant Protein-1 and Risk of Stroke
Marios K Georgakis, Rainer Malik, Harry Björkbacka, Tiberiu A Pana, Serkalem Demissie, Colby Ayers, Mohamed A Elhadad, Myriam Fornage, Alexa S Beiser, Emelia J Benjamin, Matthijs S Boekholdt, Gunnar Engström, Christian Herder, Ron C Hoogeveen, Wolfgang Koenig, Olle Melander, Marju Orho-Melander, Alexandru Schiopu, Martin Söderholm, Nick Wareham, Christie M Ballantyne, Annette Peters, Sudha Seshadri, Phyo Kyaw Myint, Jan Nilsson, James A de Lemos, Martin Dichgans
Sep 06, 2019
Nitrogen availability prevents oxidative effects of salinity on wheat growth and photosynthesis by up-regulating the antioxidants and osmolytes metabolism, and secondary metabolite accumulation.
Mohammad Abass Ahanger, Cheng Qin, Naheeda Begum, Qi Maodong, Xu Xue Dong, Mohamed El-Esawi, Mohamed A El-Sheikh, Abdulrahman A Alatar, Lixin Zhang
Nov 09, 2020
A hybrid profit and loss sharing model using interest free-debt and equity financing
In this paper two models are contrasted whereby a corporation is seeking to finance the purchase of a merchandise from a supplier through a profit and loss sharing contract. The first mode consist of financing the purchase...
Interoperability as a Key Enabler for Manufacturing in the Cloud
The emerging cloud paradigm has a prominent effect on manufacturing. The move from hardware bound systems to requirements based service
provision is enabling the transition to cloud manufacturing. A networked manufacturing...
provision is enabling the transition to cloud manufacturing. A networked manufacturing...
Solving a large-scale crew pairing problem
Airline companies seek to solve the problem of determining an assignment of crews to a pre-determined flight schedule with minimum total cost, called the Crew Pairing Problem (CPP). Most of the existing studies focus on the CPP...
Evaluation of Laparoscopy Virtual Reality Training on the Improvement of Trainees' Surgical Skills.
Mohamed Elessawy, Mohamed Mabrouk, Thorsten Heilmann, Marion Weigel, Mohamed Zidan, Ghada Abu-Sheasha, Andre Farrokh, Dirk Bauerschlag, Nicolai Maass, Mohamed Ibrahim, Dina Kamel
Feb 03, 2021
Background and objectives: The primary objective was to evaluate the benefit of training with virtual reality simulation. The secondary objective was to describe the short-term skill acquisition obtained by simulation training...
Solving a large-scale crew pairing problem
Airline companies seek to solve the problem of determining an assignment of crews to a pre-determined flight schedule with minimum total cost, called the Crew Pairing Problem (CPP). Most of the existing studies focus on the CPP...
Dynamic structure mediates halophilic adaptation of a DNA polymerase from the deep-sea brines of the Red Sea.
Masateru Takahashi, Etsuko Takahashi, Luay I Joudeh, Monica Marini, Gobind Das, Mohamed M Elshenawy, Anastassja Akal, Kosuke Sakashita, Intikhab Alam, Muhammad Tehseen, Mohamed A Sobhy, Ulrich Stingl, Jasmeen S Merzaban, Enzo Di Fabrizio, Samir M Hamdan
Nov 05, 2018
The deep-sea brines of the Red Sea are remote and unexplored environments characterized by high temperatures, anoxic water, and elevated concentrations of salt and heavy metals. This environment provides a rare system to study...
Achieving robustness to aleatoric uncertainty with heteroscedastic Bayesian optimisation
Ryan-Rhys Griffiths, Alexander A Aldrick, Miguel Garcia-Ortegon, Vidhi Lalchand, Alpha A Lee
Nov 23, 2021
Abstract: Bayesian optimisation is a sample-efficient search methodology that holds great promise for accelerating drug and materials discovery programs. A frequently-overlooked modelling consideration in Bayesian optimisation...
Interoperability as a Key Enabler for Manufacturing in the Cloud
The emerging cloud paradigm has a prominent effect on manufacturing. The move from hardware bound systems to requirements based service
provision is enabling the transition to cloud manufacturing. A networked manufacturing...
provision is enabling the transition to cloud manufacturing. A networked manufacturing...
Thirteenth Annual ENBDC Workshop
The thirteenth annual workshop of the European Network for Breast Development and Cancer (ENBDC) Laboratories Annual Workshop took place on the 28-30 April 2022 in Weggis, Switzerland and focused on methods in mammary gland...
A Model of Cloud Forensic Application With Assurance of Cloud Log
The key concepts of digital forensic investigation in cloud computing are examination and investigation. Cybercriminals target cloud-based web applications due to presence of vulnerabilities. Forensic investigation is a complex...
Published by: IGI Global Scientific Publishing
Depression amongst interns working in a tertiary care teaching Hospital in Maharashtra
Background: Internship is a crucial stage of medical school regarding student stress which can affect thepatient care negatively. Retrieving knowledge about presence of depression is therefore important in itself and iffound...
Published by: IJHS Medical Association
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